SARS-CoV-2 may be at root of mysterious hepatitis in kids: Report
2 years, 7 months ago

SARS-CoV-2 may be at root of mysterious hepatitis in kids: Report

India Today  

SARS-CoV-2 coronavirus could be causing the mysterious cases of severe hepatitis in hundreds of young children around the world, researchers suggest. According to a report posted on Saturday on medRxiv ahead of peer review, children with Covid-19 are at significantly increased risk for liver dysfunction afterward. If that were true, they theorize, then lingering particles of the coronavirus in the gastrointestinal tract in these children could be priming the immune system to over-react to adenovirus-41F with high amounts of inflammatory proteins that ultimately damage the liver. "We suggest that children with acute hepatitis be investigated for SARS-CoV-2 persistence in stool" and for other signals that the liver damage is happening because the spike protein of the coronavirus is a "superantigen" that over-sensitizes the immune system, they said.

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History of this topic

CDC probing 109 liver illnesses in kids, including 5 deaths
2 years, 7 months ago

CDC probing 109 liver illnesses in kids, including 5 deaths

Associated Press  

NEW YORK — U.S. health officials are looking into more than 100 possible cases of a mysterious and severe liver disease in children, including five deaths. In the U.S., most of the children were toddlers, nearly all were hospitalized and eight received liver transplants “It’s still a very rare occurrence,” Butler said. “A majority of these cases have recovered and …

Mysterious pediatric liver disease found in Minnesota
2 years, 7 months ago

Mysterious pediatric liver disease found in Minnesota

Associated Press  

MINNEAPOLIS — The Minnesota Department of Health said it’s investigating several severe cases of hepatitis among children and has reported the cases to the Centers for Disease Control and Prevention. The CDC continues to investigate cases of the sudden liver disease in nearly 200 children that has health authorities in several countries racing to find answers. “Why this kid had …

Explained | The mysterious hepatitis outbreak among children around the world
2 years, 7 months ago

Explained | The mysterious hepatitis outbreak among children around the world

The Hindu  

The story so far: More than ten countries across the globe, including the U.S., the U.K., Japan, Spain, Israel, and France have reported an uptick in the number of cases of acute hepatitis observed in young children. The earliest known cases of hepatitis infection of unknown origin were reported in the U.S. in October 2021, the country’s Centres for Disease …

CDC releases new clinical details in cases of unusual hepatitis in children
2 years, 7 months ago

CDC releases new clinical details in cases of unusual hepatitis in children

CNN  

CNN — The US Centers of Disease Control and Prevention continues to investigate cases of acute hepatitis with unknown causes among children and released new clinical details about some of the cases on Friday. All patients received negative test results for hepatitis viruses A, B, and C, and several other causes of pediatric hepatitis and infections were ruled out. The …

Why kids across Canada, US and Europe are suffering from hepatitis? Experts answer
2 years, 7 months ago

Why kids across Canada, US and Europe are suffering from hepatitis? Experts answer

India TV News  

Health officials are racing to investigate the sudden surge in cases of hepatitis or liver inflammation among young children in Canada, the US and several countries in Europe. "That gives rise to the possibility that this might be an unusual or mutated adenovirus," said Prof Deirdre Kelly, an expert in paediatric hepatology at Birmingham Women's & Children's Hospital. One particular …

What’s behind mysterious rise in liver disease among children?
2 years, 7 months ago

What’s behind mysterious rise in liver disease among children?

Al Jazeera  

As health experts investigate a surge in cases of hepatitis among children, Dr Khan explains the symptoms to look out for. Health experts around the world are investigating a rise in the number of cases of hepatitis, or liver inflammation, in children. More unusual still, these cases are not linked to any of the five typical strains of hepatitis – …

EXPLAINED: Scientists Investigate Hepatitis Outbreak in Children in Europe, US
2 years, 7 months ago

EXPLAINED: Scientists Investigate Hepatitis Outbreak in Children in Europe, US

News 18  

Health authorities around the world are investigating a mysterious increase in severe cases of hepatitis – inflammation of the liver – in young children. The other concern was that the cases were not linked to the typical viruses usually linked to the condition – hepatitis A, B, C, D and E. “This is still a very low number of cases, …

Hepatitis cases in children might be linked to adenovirus, UK health officials report
2 years, 7 months ago

Hepatitis cases in children might be linked to adenovirus, UK health officials report

CNN  

CNN — Health officials in the UK have released new details in their ongoing investigation of an unusual series of hepatitis cases in children. “There may be a cofactor causing a normal adenovirus to produce a more severe clinical presentation in young children,” the UK health agency said in its technical briefing Monday, “such as increased susceptibility due to reduced …

CDC issues health advisory about acute hepatitis in children
2 years, 8 months ago

CDC issues health advisory about acute hepatitis in children

CNN  

CNN — An investigation continues into cases of acute hepatitis with unknown causes among children who had adenovirus infections. In a health advisory Thursday, the US Centers for Disease Control and Prevention alerted health care providers and public health authorities to the investigation and recommended that providers consider adenovirus testing in children with hepatitis when the cause is unknown, adding …

Why the CDC issued an alert on liver damage in children
2 years, 8 months ago

Why the CDC issued an alert on liver damage in children

NPR  

Why the CDC issued an alert on liver damage in children Enlarge this image toggle caption Kevin C. Cox/Getty Images Kevin C. Cox/Getty Images Researchers are investigating a possible connection between children infected with hepatitis and adenoviruses and liver damage in children. According to the advisory, a cluster of kids in an Alabama children's hospital developed liver damage — liver …

What's the 'mystery' liver disease that's making kids in the US, Europe sick?
2 years, 8 months ago

What's the 'mystery' liver disease that's making kids in the US, Europe sick?

Firstpost  

Even though some children have tested positive for SARS-CoV-2 and adenoviruses, health officials are still looking for a genetic characterisation of the viruses to determine any potential associations between cases Children in several countries, including the US and the UK, are coming down with a mysterious liver disease that has led health officials to investigate its origins. The World Health …

Drug that may treat serious COVID-19 complication in children identified
2 years, 10 months ago

Drug that may treat serious COVID-19 complication in children identified

Deccan Chronicle  

Washington: Scientists have identified a promising drug candidate for the treatment of a rare but severe, and potentially life-threatening condition in children infected with the SARS-CoV-2 virus, that causes COVID-19. "Working collaboratively, we have been able to demonstrate that viral particles that remain in the gut long after COVID-19 infection can instigate MIS-C," said David Walt, senior author of the …

Covid-19: Are we detecting coronavirus the right way? New researches pose questions
4 years, 2 months ago

Covid-19: Are we detecting coronavirus the right way? New researches pose questions

India Today  

Is Covid-19 only a respiratory illness? What scientists have found is that a fairly large number of Covid-19 patients have complaints of gut dysbiosis - a medical term used to describe microbial imbalance - after reporting negative in the SARS-CoV-2 coronavirus test and long after showing initial respiratory symptoms for the pandemic illness. That Covid-19 could equally be a gastrointestinal …

Watch | COVID-19 and children
4 years, 3 months ago

Watch | COVID-19 and children

The Hindu  

The COVID-19 pandemic has kept paediatricians busy with worried parents seeking advice for the best possible way to protect children from SARS-CoV-2. A recent study by Researchers at Massachusetts General Hospital and Mass General Hospital for Children has found that infected children have a viral load comparable with adults in ICUs for COVID-19 treatment. A study published in The Lancet …

Children Play Larger Role in Community Spread of Covid-19, Finds New Study
4 years, 4 months ago

Children Play Larger Role in Community Spread of Covid-19, Finds New Study

News 18  

New York: While most studies have stressed that children are not the harbingers of Covid-19, a comprehensive study now claims that children play a larger role in the community spread of the novel coronavirus than previously thought. In the Mass General Hospital for Children study, 51 per cent of children with acute SARS-CoV-2 infection came from low-income communities compared to …

High virus in kids with Covid-19, but are they contagious?
4 years, 4 months ago

High virus in kids with Covid-19, but are they contagious?

Hindustan Times  

Coronavirus disease rarely sickens children, and when it does, it usually causes mild disease. But a new study indicates that infected children with mild and moderate disease carry as much virus as adults, sparking debate on whether they can potentially spread infection as easily as adults. Infected children with mild and moderate disease carry as much virus as adults, a …

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