
Op-Ed: New COVID variants like BA.5 are dominating us — we can do more to prevent this
LA TimesIt takes a lot for a COVID-19 variant to become dominant throughout most of the world. In the last weeks BA.5 became the dominant COVID variant in the United States, according to the Centers for Disease Control and Prevention, the cause of nearly 54% of new cases, growing exponentially here since late April. The reason why BA.5 is a standout is predominantly linked to its property of “immune escape.” That is, multiple distinct mutations from prior Omicron variants have blunted our immune response to it. BA.5 doesn’t completely evade our defenses — there is some cross-immunity that is enabled by vaccines and prior infections, reflected in sustained protection from the most severe COVID illness. The transition from Omicron BA.1, first picked up spreading in late November 2021, to BA.5 now, with many other Omicron subvariants in between, is quite rapid and unlike the first year of the pandemic when there were no substantive new versions of the virus seen.
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