WHO Solidarity Trials find Remdesivir, HCQ, HIV drug, interferon ineffective in treating COVID-19
4 years, 2 months ago

WHO Solidarity Trials find Remdesivir, HCQ, HIV drug, interferon ineffective in treating COVID-19

Firstpost  

The WHO’s Solidarity Therapeutics Trial was conducted in 11,266 adult patients in 405 hospitals across more than 30 countries. The World Health Organization’s Solidarity trial is the world’s largest ongoing randomized control trial of potential COVID-19 therapeutics. Based on data collected from the trial, the WHO has released an interim report of patients’ responses to repurposed drugs for COVID-19 treatment. These permissions could now change basis the Solidarity trial findings, which includes 11,266 patients hospitalized with COVID-19, spread across 30 countries. According to a report by Reuters, data from a US study of remdesivir lead by Gilead showed the use of the treatment cut COVID-19 recovery time by five days in a trial comprising 1,062 patients.

Solidarity Trial Drugs Trials Patients Drug Reuters Interferon Hcq Remdesivir Lopinavir  remdesivir  trial  ineffective  drug  hcq  treating  data  patients  interferon  solidarity  hiv  drugs  study  covid19  trials  studies

History of this topic

FDA revokes authorization for key anti-COVID drug, a blow for vulnerable Americans
1 year, 10 months ago

FDA revokes authorization for key anti-COVID drug, a blow for vulnerable Americans

LA Times  

A two-shot dose of Evusheld at a University of Washington Medicine clinic in Seattle. For her patients, she said, “it was kind of like being told the seat belts in your car won’t work anymore, and we’re not going to be able to replace them with anything.” In recent months, nine new subvariants of the dominant Omicron strain have proven …

VINCOV-19, country’s first anti-dote for COVID, ready for phase 3 trials, market authorisation
2 years, 2 months ago

VINCOV-19, country’s first anti-dote for COVID, ready for phase 3 trials, market authorisation

The Hindu  

The University of Hyderabad and CSIR-Centre for Cellular & Molecular Biology in collaboration with VINS Bioproducts Limited, an immunological company based here, have announced the successful completion of phase 2 clinical trials of ‘VINCOV-19’, touted to be the country’s first antidote and a cure against SARS-CoV-2 virus. VINCOV-19 is now ready for market authorisation and for simultaneous phase 3 clinical …

Man who was in medically induced coma hails Covid drug trial for survival
2 years, 6 months ago

Man who was in medically induced coma hails Covid drug trial for survival

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. His wife enrolled him in the Recovery trial for dexmethasone, which is now estimated to …

WHO recommends Pfizer's pill Paxlovid for mild Covid cases
2 years, 8 months ago

WHO recommends Pfizer's pill Paxlovid for mild Covid cases

India Today  

The World Health Organisation has strongly recommended nirmatrelvir and ritonavir, sold under the name Paxlovid, for mild and moderate Covid-19 patients at highest risk of hospital admission. Pfizer’s oral antiviral drug is strongly recommended for patients with non-severe Covid-19 who are at highest risk of developing severe disease and hospitalisation, such as unvaccinated, older, or immunosuppressed patients. The global health …

Health Matters: Dear Drug Regulator, Silence is Not Always Golden, Esp on WHO Pausing Covaxin Supply
2 years, 8 months ago

Health Matters: Dear Drug Regulator, Silence is Not Always Golden, Esp on WHO Pausing Covaxin Supply

News 18  

On April 2, the World Health Organization suspended the supply of Bharat Biotech’s Covaxin through the UN agencies after finding issues with the “good manufacturing practices”. For the past 15 days, not only health journalists, but even commoners who got Covaxin jabs are hoping to hear from the country’s drug regulatory agency – Central Drugs Standard Control Organization. Eventually, the …

Health Matters: Don't Feel Guilty About Not Finding Remdesivir for Your Loved One. It Hardly Works
2 years, 11 months ago

Health Matters: Don't Feel Guilty About Not Finding Remdesivir for Your Loved One. It Hardly Works

News 18  

It was dinner time when she called for help. They don’t want to use it, but keep it.” Much before the outbreak of second wave, in November 2020, the World Health Organization issued a conditional recommendation against the use of Remdesivir in hospitalised patients, regardless of disease severity saying “there is currently no evidence that Remdesivir improves survival and other …

New COVID-19 treatment rules: India cuts down use of Remdesivir, Tocilizumab, multivitamins, steroids
2 years, 11 months ago

New COVID-19 treatment rules: India cuts down use of Remdesivir, Tocilizumab, multivitamins, steroids

Firstpost  

According to the new guidelines, Remdesivir may be considered only in patients who have completed 10 days since the start of the symptoms and require supplemental oxygen. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with COVID-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the …

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment
2 years, 11 months ago

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment

News 18  

India has cut down on the use of the experimental drug Remdesivir and immunosuppressive drug Tocilizumab for the treatment of Covid-19. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with Covid-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the overuse of steroids, the protocol for …

WHO adds new drugs to COVID treatments amid Omicron surge
2 years, 11 months ago

WHO adds new drugs to COVID treatments amid Omicron surge

Al Jazeera  

Latest recommendations prompt new calls for patent waivers to allow more people access to treatments. The drug baricitinib, which is also used to treat rheumatoid arthritis, is “strongly recommended” for patients with severe or critical COVID-19, in combination with corticosteroids, the UN agency’s panel of international experts said in the guidelines which were published by the British Medical Journal on …

A shot in the arm: The Hindu Editorial on new modes of COVID-19 treatment
3 years ago

A shot in the arm: The Hindu Editorial on new modes of COVID-19 treatment

The Hindu  

If full vaccination using any COVID-19 vaccine greatly reduces a person’s risk of progressing to severe disease and death, then the move by the U.S. FDA to grant emergency-use authorisation to two oral antiviral drugs for certain categories of people who are likely to become severely ill provides a much-needed fillip to fight the disease. Unlike in the case of …

Merck's Covid-19 pill Molnupiravir found to reduce hospitalisation, death risks
3 years ago

Merck's Covid-19 pill Molnupiravir found to reduce hospitalisation, death risks

India Today  

As Covid-19 cases peak across the world including the US and the UK, Molnupiravir, an oral drug developed by Merck, could act as a counter. In the phase-III clinical trials, the drug was found to reduce the risk of hospitalisation and death in at-risk, unvaccinated adults, Molnupiravir is an oral, small-molecule antiviral prodrug that is active against severe acute respiratory …

Merck’s COVID pill shows lower efficacy in updated study
3 years ago

Merck’s COVID pill shows lower efficacy in updated study

Al Jazeera  

Drugmaker says final analysis of trial results showed molnupiravir led to 30 percent reduction in hospitalisations and deaths, compared with about 50 percent in interim study. Drugmaker Merck’s experimental COVID-19 pill is significantly less effective in slashing hospitalisations and deaths than previously reported, the company has said, following the release of a full analysis of trial results. The United States-based …

EU regulator recommends Merck’s COVID-19 pill for emergency use
3 years, 1 month ago

EU regulator recommends Merck’s COVID-19 pill for emergency use

Al Jazeera  

The European Union’s medicines watchdog has advised its member states they can use a potentially groundbreaking COVID-19 antiviral pill in emergency situations triggered by soaring infection rates, ahead of the treatment’s formal approval across the bloc. Molnupiravir, which is produced by Merck and Ridgeback Biotherapeutics, can be given within five days of first symptoms to treat adults who do not …

Pfizer says COVID-19 pill cut hospital, death risk by 90%
3 years, 1 month ago

Pfizer says COVID-19 pill cut hospital, death risk by 90%

Associated Press  

WASHINGTON — Pfizer Inc. said Friday that its experimental antiviral pill for COVID-19 cut rates of hospitalization and death by nearly 90% in high-risk adults, as the drugmaker joined the race for an easy-to-use medication to treat the coronavirus. Competitor Merck’s COVID-19 pill is already under review at the Food and Drug Administration after showing strong initial results, and on …

Molnupiravir: UK authorizes Merck/Ridgeback Biotherapeutics’ antiviral to treat mild-to-moderate Covid-19
3 years, 1 month ago

Molnupiravir: UK authorizes Merck/Ridgeback Biotherapeutics’ antiviral to treat mild-to-moderate Covid-19

CNN  

CNN — The UK Medicines and Healthcare Products Regulatory Agency said Thursday it had authorized Merck and Ridgeback Biotherapeutics’ oral antiviral, molnupiravir, to treat mild-to-moderate Covid-19 in adults at risk for severe illness. The companies have sought US Food and Drug Administration emergency use authorization for the drug, and the FDA said it will convene its Antimicrobial Drugs Advisory Committee …

UK approves Merck’s antiviral COVID-19 pill in world first move
3 years, 1 month ago

UK approves Merck’s antiviral COVID-19 pill in world first move

Al Jazeera  

Merck’s molnupiravir to be given to recently-infected COVID-19 patients twice a day, for five days. The United Kingdom has become the first country in the world to approve a potentially game-changing COVID-19 antiviral pill jointly developed by Merck and Ridgeback Biotherapeutics. Merck’s molnupiravir has been closely watched since data last month showed it could halve the chances of dying or …

Merck seeks FDA emergency use authorization for experimental antiviral Covid-19 treatment molnupiravir
3 years, 2 months ago

Merck seeks FDA emergency use authorization for experimental antiviral Covid-19 treatment molnupiravir

CNN  

CNN — Merck said Monday it is seeking US Food and Drug Administration emergency use authorization for its experimental antiviral Covid-19 treatment, molnupiravir. “At the interim analysis, molnupiravir reduced the risk of hospitalization or death by approximately 50%; 7.3% of patients who received molnupiravir were either hospitalized or died through Day 29 following randomization, compared with 14.1% of placebo-treated patients,” …

Merck seeks US authorisation for pill to treat COVID
3 years, 2 months ago

Merck seeks US authorisation for pill to treat COVID

Al Jazeera  

US pharmaceutical giant submits request for FDA approval for molnupiravir pill to treat mild-to-moderate COVID-19 cases. US pharmaceutical company Merck has requested emergency authorisation for its experimental pill to treat mild-to-moderate cases of COVID-19, in what would add a promising, new tool to the global fight against the virus. Merck submitted the application for molnupiravir, which it said earlier this …

2 Indian Firms Seek Regulator Nod to Cease Trials of anti-Covid Pill Molnupiravir on 'Moderate' Patients
3 years, 2 months ago

2 Indian Firms Seek Regulator Nod to Cease Trials of anti-Covid Pill Molnupiravir on 'Moderate' Patients

News 18  

Two pharmaceutical companies have sought permission from India’s drug regulator to discontinue the phase III trials of American firm Merck & Co’s experimental antiviral drug molnupiravir in moderate Covid-19 patients, a government document shows, though one of the two manufacturers told News18.com that the “results have come out exceedingly well” in mild cases. Aurobindo Pharma and MSN Laboratories have presented …

EXPLAINED: A Pill You Can Pop At Home To Beat Covid. Here's Why Merck's Antiviral Drug Is Raising Hopes
3 years, 2 months ago

EXPLAINED: A Pill You Can Pop At Home To Beat Covid. Here's Why Merck's Antiviral Drug Is Raising Hopes

News 18  

The global death toll from Covid-19 is said to now have crossed 5 million even as the pandemic’s end is yet to appear within sight. Merck, which has partnered the US-based Ridgeback Biotherapeutics for the development of the drug, said that Phase-3 trials showed that it “significantly reduced the risk of hospitalisation or death… in at risk, non-hospitalised adult patients …

Explained | Molnupiravir, Merck’s new drug to treat COVID-19
3 years, 2 months ago

Explained | Molnupiravir, Merck’s new drug to treat COVID-19

The Hindu  

Why is there much excitement about molnupiravir, the investigational new drug for COVID-19? Pharmaceutical major Merck and Ridgeback Biotherapeutics announced via a press release on October 1 the early results from Phase-3 trials that its anti-viral drug molnupiravir halved the chances of hospitalisation in COVID-19 patients with mild or moderate disease. Several noted clinicians have said that these are promising …

Merck’s Molnupiravir, Glenmark’s Nasal Spray, Zydus' Antibody Cocktail: 20+ Drugs in Pipeline for Covid
3 years, 2 months ago

Merck’s Molnupiravir, Glenmark’s Nasal Spray, Zydus' Antibody Cocktail: 20+ Drugs in Pipeline for Covid

News 18  

Merck’s Molnupiravir, Zydus’ antibody cocktail and Glenmark’s nasal spray are among more than 20 new drugs in different stages of drug trials or approvals in India to treat Covid-19. “As the world needs Covid-19 vaccines, the world also needs proven and effective Covid-19 therapies,” Lahariya said. List of Drugs in the Pipeline US pharma giant Merck and Ridgeback Biotherapeutics’ oral …

Merck Covid pill: What would an antiviral pill mean for the fight against Covid-19?
3 years, 2 months ago

Merck Covid pill: What would an antiviral pill mean for the fight against Covid-19?

CNN  

CNN — Merck and Ridgeback Biotherapeutics announced on Friday early result that indicate their experimental oral antiviral drug molnupiravir might halve the risk of death or hospitalization from Covid-19. But Merck says it will seek authorization from the US Food and Drug Administration, and if it’s granted, the drug could be the first antiviral treatment available orally to fight Covid-19. …

Merck says COVID-19 pill cuts risk of death, hospitalization
3 years, 2 months ago

Merck says COVID-19 pill cuts risk of death, hospitalization

Associated Press  

WASHINGTON — In a potential leap forward in the global fight against the pandemic, drugmaker Merck said Friday that its experimental pill for people sick with COVID-19 reduced hospitalizations and deaths by half. Merck and its partner Ridgeback Biotherapeutics said early results showed patients who received the drug, molnupiravir, within five days of COVID-19 symptoms had about half the rate …

Merck says its experimental pill cuts COVID-19 hospitalizations and deaths by half
3 years, 2 months ago

Merck says its experimental pill cuts COVID-19 hospitalizations and deaths by half

LA Times  

Drugmaker Merck says its experimental COVID-19 pill reduced hospitalizations and deaths by half in newly infected people. Drugmaker Merck said Friday that its experimental antiviral pill cuts rates of severe disease and death in half for newly diagnosed COVID-19 patients at high risk of becoming seriously ill. Health experts from Dr. Anthony Fauci on down have long called for a …

WHO to trial malaria, arthritis drugs as COVID treatments
3 years, 4 months ago

WHO to trial malaria, arthritis drugs as COVID treatments

Al Jazeera  

Three drugs will be added to the UN agency’s global trial to test their efficacy in patients hospitalised with COVID-19. The World Health Organization will test three new drugs as potential treatments for people in hospital with severe COVID-19 as it expands its global trial to 52 countries. Artesunate is currently used for severe malaria, imatinib for certain cancers, and …

WHO Tests 3 Drugs for Treating Coronavirus Infection
3 years, 4 months ago

WHO Tests 3 Drugs for Treating Coronavirus Infection

News 18  

The World Health Organization says it will soon test three drugs used for other diseases to see if they might help patients sickened by the coronavirus. In a statement on Wednesday, the U.N. health agency says the three drugs would be adopted into the next phase of its ongoing global research into identifying potential treatments for COVID-19. The drugs were …

US to spend $3.2B on treatments for COVID-19, other viruses
3 years, 6 months ago

US to spend $3.2B on treatments for COVID-19, other viruses

Associated Press  

WASHINGTON — The United States is devoting $3.2 billion to speed development of antiviral pills to treat COVID-19 and other dangerous viruses that could turn into pandemics. The new program will invest in “accelerating things that are already in progress” for COVID-19 but also would work to come up with treatments for other viruses, said Dr. Anthony Fauci, the nation’s …

Biden administration will spend $3.2 billion on development of antiviral pills for treating COVID-19
3 years, 6 months ago

Biden administration will spend $3.2 billion on development of antiviral pills for treating COVID-19

Daily Mail  

The Biden administration is devoting $3.2 billion to help develop antiviral pills to treat COVID-19, officials said on Thursday. The U.S. government has committed $3.2 billion to help develop antiviral pills to treat COVID-19, officials including Dr Anthony Fauci announced on Thursday Several pills are in development that will be used to minimize symptoms of the virus early on in …

U.S. to spend $3.2 billion on treatments for COVID-19 and other viral diseases
3 years, 6 months ago

U.S. to spend $3.2 billion on treatments for COVID-19 and other viral diseases

LA Times  

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, speaks May 11 at a hearing on Capitol Hill. The new program will invest in “accelerating things that are already in progress” for COVID-19 but also would work to come up with treatments for other viral conditions, said Dr. Anthony Fauci, the nation’s top infectious disease expert. …

Govt Issues Advisory for Rational Use of Remdesivir in Covid-19 Treatment
3 years, 6 months ago

Govt Issues Advisory for Rational Use of Remdesivir in Covid-19 Treatment

News 18  

The government on Monday issued an advisory for rational use of Remdesivir in COVID-19 treatment, underlining that the anti-viral drug must be advised by senior faculty members directly involved in the patient's care. To stop the misuse of Remdesivir, the government further recommended that if the drug is to be advised or ordered during odd hours, it should be done …

No evidence of Remdesivir's effectiveness, might be dropped as COVID-19 treatment: Dr DS Rana
3 years, 7 months ago

No evidence of Remdesivir's effectiveness, might be dropped as COVID-19 treatment: Dr DS Rana

Firstpost  

Ganga Ram hospital Chairperson Dr DS Rana said, “Medicines that do not have any activity to work, will have to be discontinued.” Ganga Ram hospital Chairperson Dr DS Rana on Tuesday said that Remdesivir is also being considered to be dropped from COVID-19 treatment soon as there is no evidence of its effectiveness in treating COVID-19 patients. While talking to …

Remdesivir Sale To Be Shifted To Chennai Nehru Indoor Stadium
3 years, 7 months ago

Remdesivir Sale To Be Shifted To Chennai Nehru Indoor Stadium

The Quint  

Chief Minister MK Stalin recently announced that the government will open Remdesivir counters at Madurai, Coimbatore, Trichy and Tirunelveli to address the state-wide shortage of the anti viral drug. In its submissions to the Madras HC, the state government added that it had received 250,000 vials of Remdesivir so far and the minimum requirement in the state was 20,000 vials …

Coronavirus Fact Check: Is Remdesivir life saving drug in COVID19, can it be given to patients at home?
3 years, 7 months ago

Coronavirus Fact Check: Is Remdesivir life saving drug in COVID19, can it be given to patients at home?

India TV News  

During COVID 19 second wave in India, a number of people are seen hunting for oxygen cylinders, ICU beds and many more medical facilities across the country. Know all about it here: According to an infographic video shared by PIB fact check, a verified Twitter account by the government of India to counter misinformation on govt. Meanwhile, India recorded 362,727 …

WHO to restart Covid drug trial with focus on immune responses
3 years, 7 months ago

WHO to restart Covid drug trial with focus on immune responses

India TV News  

The World Health Organization is set to restart an international clinical trial of three existing drugs that can save the lives of people hospitalised with Covid-19. The latest trial will test three drugs that dampen inflammation -- Infliximab, Imatinib and Artesunate. And we need to study drugs that we can deliver in a broad group of countries," added Rottingen, who …

What Widespread Recommendation of Remdesivir for COVID-19 and Its Shortage Teach Us
3 years, 7 months ago

What Widespread Recommendation of Remdesivir for COVID-19 and Its Shortage Teach Us

News 18  

Soon after the start of the second wave of COVID-19 pandemic in India, the images of people standing in long queues outside the chemist stores/pharmacies across India, were all over the newspapers. Though clinical trials have not found Remdesivir beneficial in COVID-19 treatment; however, clinicians in India and even the national COVID-19 task force and expert groups in India continue …

Doctors divided over use but scramble for Remdesivir continues
3 years, 7 months ago

Doctors divided over use but scramble for Remdesivir continues

The Hindu  

The scramble for Remdesivir, the anti-viral drug used in COVID-19 management, is increasing by the day even as doctors are divided on its use. Private Hospitals and Nursing Homes Association president H.M. Prasanna said that the helpline set up by the government is of little use. Manjunath, nodal officer for labs and testing in the State’s COVID-19 task force, said …

'Not a Life-Saving Drug': ICMR Suggests Safe Use of Remdesivir in Covid-19
3 years, 8 months ago

'Not a Life-Saving Drug': ICMR Suggests Safe Use of Remdesivir in Covid-19

News 18  

The Indian Council of Medical Research on Tuesday shared some suggestions for rational and safe use of Remdesivir in Covid-19 as the demand for the medicine has increased for treating coronavirus patients especially in Covid-hit states including Maharashtra, Delhi, Karnataka and others. Remdesivir is one of the investigational drugs approved for emergency use in treating hospitalized Covid-19 patients. Suggestion for …

Remdesivir Not Magic Bullet, Does Not Reduce Covid-19 Mortality: AIIMS Chief Randeep Guleria
3 years, 8 months ago

Remdesivir Not Magic Bullet, Does Not Reduce Covid-19 Mortality: AIIMS Chief Randeep Guleria

News 18  

Amid a steep spike in COVID-19 cases leading to increased demand for medicines for treating coronavirus, top health experts in the government on Monday said anti-viral drug remdesivir is "not a magic bullet" and does not reduce mortality. Addressing the media, AIIMS Director Dr Randeep Guleria said remdesivir should only be given to patients hospitalised with moderate illness, who had …

Amid Covid Spurt, Medicos Advice People To Use Remdesivir Judiciously and Only in a Hospital Setting
3 years, 8 months ago

Amid Covid Spurt, Medicos Advice People To Use Remdesivir Judiciously and Only in a Hospital Setting

News 18  

Amid a fight to acquire Remdesivir for ailing Covid-19 patients, a group of medical experts, professionals, and task-forces have stated that the injection can only be used inside a hospital setting. Maharashtra’s Covid-19 Task Force member Dr. Shashank Joshi took to Twitter to put out a statement saying that Remdesivir is not a ‘life-saving’ drug. The statement also made it …

Why Indian doctors prescribe Remdesivir for Covid-19 despite negative global medical view
3 years, 8 months ago

Why Indian doctors prescribe Remdesivir for Covid-19 despite negative global medical view

India Today  

While a cacophony has broken out over the shortage of Remdesivir injections across the country, international health experts are wondering why it is so widely being prescribed in India. Dr Aviral Vatsa of the National Health Services Scotland said, “The UK guidelines, the Stanford US guidelines or even WHO guidelines have clearly said that there is no clear evidence any …

No evidence of Remdesivir's effectiveness in treating Covid patients: WHO
3 years, 8 months ago

No evidence of Remdesivir's effectiveness in treating Covid patients: WHO

India Today  

Amid the surge in demand for antiviral drug Remdesivir, the World Health Organization has said that there is still no evidence to suggest that the drug is useful in treating hospitalised Covid-19 patients. WHO's Chief Scientist Dr Soumya Swaminathan and its Technical Lead on Covid, Dr Maria Van Kerkhove on Monday told India Today TV that results from five clinical …

Do not use 'miracle cure' ivermectin on COVID-19 patients says WHO
3 years, 8 months ago

Do not use 'miracle cure' ivermectin on COVID-19 patients says WHO

Firstpost  

The World Health Organization said Wednesday that ivermectin — touted by some on social media as a Covid-19 “miracle cure” — should not be used to treat coronavirus patients. The WHO said: “We recommend not to use ivermectin in patients with Covid-19 except in the context of a clinical trial.” Facebook posts and articles endorsing ivermectin have proliferated in Brazil, …

The disease-resistant patients exposing Covid-19's weak spots
3 years, 10 months ago

The disease-resistant patients exposing Covid-19's weak spots

BBC  

The disease-resistant patients exposing Covid-19's weak spots Ying Tang/Getty Images There are some people whose bodies have reacted differently to Covid-19 compared to the rest of the population Some people are unusually resilient to the coronavirus, so scientists are now searching their genes and blood in the hope of finding the pandemic's Achilles' heel. "The idea is to try and …

Study shows Covid-19 evolved during treatment, convalescent plasma therapy patients had UK mutant
3 years, 10 months ago

Study shows Covid-19 evolved during treatment, convalescent plasma therapy patients had UK mutant

India Today  

A recent study has revealed that the dominant variant of the novel coronavirus or Covid-19 that emerged in patients after the convalescent plasma therapy possessed a mutation that is also present in the one first discovered in the UK. ".data reveal strong selection on SARS-CoV-2 during convalescent plasma therapy associated with the emergence of viral variants with evidence of reduced …

UK scientists trial instant immunity antibody drug treatment for COVID-19
3 years, 11 months ago

UK scientists trial instant immunity antibody drug treatment for COVID-19

India TV News  

Scientists in the UK have begun trials of innovative antibody drug treatments that they hope could provide instant protection against COVID-19. The University College London Hospitals NHS Trust said that the researchers in the Storm Chase study believe a Long Acting AntiBody known as AZD7442, developed by AstraZeneca, may offer immediate and long-term protection to people who have been recently …

UK Scientists Trial Instant Immunity Antibody Drug Treatment for Coronavirus
3 years, 11 months ago

UK Scientists Trial Instant Immunity Antibody Drug Treatment for Coronavirus

News 18  

Scientists in the UK have begun trials of innovative antibody drug treatments that they hope could provide instant protection against COVID-19. The University College London Hospitals NHS Trust said that the researchers in the Storm Chase study believe a Long Acting AntiBody known as AZD7442, developed by AstraZeneca, may offer immediate and long-term protection to people who have been recently …

COVID-19 patients are being treated with drugs such as itolizumab even though there is insufficient evidence on their efficacy against the disease
4 years ago

COVID-19 patients are being treated with drugs such as itolizumab even though there is insufficient evidence on their efficacy against the disease

The Hindu  

THE COVID-19 caseload continues to rise in India, with State governments, including those of Delhi and the industrial hub Maharashtra, signalling that their States are experiencing new waves of the pandemic. It has been confirmed that during the clinical phase II trial for the drug itolizumab —which is manufactured and marketed by Biocon Biologics, a subsidiary of Biocon Limited, founded …

Trial comprising single Covid patient with genetic disorder shows remdesivir's benefits: Study
4 years ago

Trial comprising single Covid patient with genetic disorder shows remdesivir's benefits: Study

India Today  

Gilead's antiviral drug remdesivir could be highly effective against coronavirus, a study conducted by British scientists has found. The study, published in the journal Nature Communications involved a single Covid-19 patient with XLA, a rare genetic disorder. Nicholas Matheso, a co-author of the study, told news agency Reuters, "Our patient's unusual condition gave us a rare insight into the effectiveness …

Coronavirus pandemic: WHO advises doctors not to use Gilead’s Remdesivir for Covid-19 treatment
4 years, 1 month ago

Coronavirus pandemic: WHO advises doctors not to use Gilead’s Remdesivir for Covid-19 treatment

Hindustan Times  

The World Health Organization recommended against using Gilead Sciences Inc.’s remdesivir to treat hospitalized Covid-19 patients less than a month after U.S. regulators granted the drug a speedy approval. “But personally, our view in our industry is to use the better controlled studies to evaluate the benefits of medicines.” ‘Relatively High Cost’ The FDA originally granted emergency use authorization to …

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