Utrecht researchers find new treatment for intubated Covid-19 patients
4 years, 1 month ago

Utrecht researchers find new treatment for intubated Covid-19 patients

NL Times  

Researchers found that existing medicine Tocilizumab, used for rheumatoid arthritis, can shorten the length of time seriously ill Covid-19 patients have to be intubated and in intensive care. Doctor and microbiologist at the Utrecht hospital Marc Bonten called it "really good news" for patients, speaking to ANP. "It is precisely for the group of seriously ill people in intensive care that we have not often seen a new treatment proven to be effective. "We think that patients with Covid-19 who come to intensive care are not so much sick from the virus itself, but from the overreaction of the immune system to the virus."

Intensive Care Utrecht  study  researchers  umc  intubated  system  intensive  utrecht  patients  covid19  seriously  treatment  care

History of this topic

Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study
2 years, 10 months ago

Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study

Hindustan Times  

An anti-inflammatory drug normally used to treat rheumatoid arthritis reduces the risk of death when given to hospitalised patients with severe Covid-19, according to a study led by researchers at the University of Oxford. Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study The benefit of baricitinib is in addition to those of dexamethasone and tocilizumab, two other …

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment
2 years, 11 months ago

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment

News 18  

India has cut down on the use of the experimental drug Remdesivir and immunosuppressive drug Tocilizumab for the treatment of Covid-19. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with Covid-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the overuse of steroids, the protocol for …

Lessons from COVID-19
3 years, 8 months ago

Lessons from COVID-19

The Hindu  

The SARS-CoV-2 pandemic was declared by the World Health Organization on March 11, 2020. It is important that lack of benefit of these drugs reported in well-conducted clinical trials should be translated into clinical practice by healthcare professionals managing COVID-19 patients. More recently, we have emerging evidence that two interleukin-6 receptor blocking drugs benefit COVID-19 patients, including enhanced benefit when …

Timely treatment with tocilizumab likely to improve clinical outcomes in severe COVID-19 patients, finds study
4 years, 2 months ago

Timely treatment with tocilizumab likely to improve clinical outcomes in severe COVID-19 patients, finds study

Firstpost  

The drug is already approved and is used for the treatment of rheumatoid arthritis, an autoimmune disease that leads to joint inflammation and pain Patients with severe COVID-19 are likely to have short-term mortality rates between 35 percent to 62 percent, according to a study published in the journal JAMA Internal Medicine. A group of researchers at US’ Birmingham and …

Antibody Drug Itolizumab Lowers Risk of Death in Elderly Covid-19 Patients, Says Cuban Study
4 years, 5 months ago

Antibody Drug Itolizumab Lowers Risk of Death in Elderly Covid-19 Patients, Says Cuban Study

News 18  

An antibody drug already being used against the coronavirus in Cuba decreased the risk of intensive care admission and death among nursing home residents with moderate COVID-19, according to a small study conducted in the island nation. Researchers, including from Cuba's Center of Molecular Immunology, which developed itolizumab, said timely use of the drug in combination with standard therapy helped …

Coronavirus | No evidence yet that itolizumab, tocilizumab reduces deaths: ICMR head
4 years, 5 months ago

Coronavirus | No evidence yet that itolizumab, tocilizumab reduces deaths: ICMR head

The Hindu  

There is yet no evidence from trials that itolizumab and tocilizumab, two drugs, one of which has been developed by Bengaluru-based Biocon Biologics, reduce death in severely ill coronavirus patients, Director-General of the ICMR Balram Bhargava said at a Health Ministry press briefing on Tuesday. Biocon’s COVID-19 drug tested on too few patients to reliably conclude on benefits, say experts …

COVID-19 treatments: Which drugs, therapies are proven to work, and which ones don’t?
4 years, 6 months ago

COVID-19 treatments: Which drugs, therapies are proven to work, and which ones don’t?

Firstpost  

We have made amazing progress in the treatment of COVID-19. Ritonavir increases the level of Lopinavir in the blood so the lopinavir/ritonavir combination was tested in a randomized controlled clinical trial for COVID-19. Steroids – yes for almost all COVID-19 patients When a synthetic steroid hormone, called dexamethasone, was given to patients with COVID-19 the drug decreased 28-day mortality by …

California doctor says arthritis drug improved coronavirus patients' symptoms within 72 hours
4 years, 8 months ago

California doctor says arthritis drug improved coronavirus patients' symptoms within 72 hours

Daily Mail  

Dr Imran Sharief, a pulmonologist from California, gave tocilizumab, a drug used to treat rheumatoid arthritis, to severely ill COVID-19 patients A California physician says a rheumatoid arthritis drug could be an effective treatment for coronavirus. Dr Imran Sharief, a pulmonologist based in Santa Ana, told Fox News that he treated COVID-19 patients on ventilators with tocilizumab, sold under the …

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