Antibody from common cold reacts to COVID infection: Study
3 years, 6 months ago

Antibody from common cold reacts to COVID infection: Study

India TV News  

US researchers have identified that a special type of antibody is produced in patients who've had Covid-19 as well as common colds, an advance that may be the starting point for broader-acting vaccines. The study, by a team from the Scripps Research Institute, found that the cross-reactive antibody is produced by a memory B cell -- an essential part of the immune system. "We were able to determine that this type of cross-reactive antibody is likely produced by a memory B cell that's initially exposed to a coronavirus that causes the common cold, and is then recalled during a Covid-19 infection," said senior author Raiees Andrabi, an investigator from the varsity's Department of Immunology and Microbiology. Our identification of a cross-reactive antibody against SARS-CoV-2 and the more common coronaviruses is a promising development on the way to a broad-acting vaccine or therapy," Burton noted.

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History of this topic

'Coldspots' discovered in Covid virus, may help antibodies fight future variants: Study
1 year, 10 months ago

'Coldspots' discovered in Covid virus, may help antibodies fight future variants: Study

India TV News  

Scientists have discovered regions on the coronavirus which do not change, or 'coldspots', and that antibodies specific for these coldspots may help fight future coronaviruses, according to a new study. According to the study, sieving through over 10 million coronavirus sequences, two PhD students at the Institute for Research in Biomedicine, Switzerland and affiliated with the Università della Svizzera italiana, …

Multipronged vaccine protects against COVID virus family members — even some still in hiding
2 years, 5 months ago

Multipronged vaccine protects against COVID virus family members — even some still in hiding

LA Times  

Researchers at Caltech have devised an experimental vaccine that targets an array of coronaviruses and variants in a single shot. “We’ve had three pandemics or epidemics in the past 20 years: first SARS, then MERS, then SARS-CoV-2,” said Caltech biochemist Pamela Bjorkman, who led the new work. More outbreaks sparked by “spillover events” are inevitable, she said, and “we want …

Chinese scientists design cocktail antibody to treat, prevent COVID-19
2 years, 9 months ago

Chinese scientists design cocktail antibody to treat, prevent COVID-19

China Daily  

BEIJING -- Chinese scientists designed a cocktail antibody that can deliver a one-two punch to the coronavirus that causes COVID-19. The researchers from Capital Medical University and Chinese Academy of Sciences developed the bispecific human monoclonal antibody against SARS-CoV-2, combining a noncompeting pair of human neutralizing antibodies, namely B38 and H4, to target two antigens, thus blocking the virus from …

Common cold T cells may offer protection against Covid-19: UK study
2 years, 11 months ago

Common cold T cells may offer protection against Covid-19: UK study

India Today  

People with higher levels of T cells from common cold coronaviruses are less likely to become infected with SARS-CoV-2, the strain which causes Covid-19, according to a new UK study led by Indian-origin researchers on Monday. Our study provides the clearest evidence to date that T cells induced by common cold coronaviruses play a protective role against SARS-CoV-2 infection. These …

T-cells from common colds can provide protection against COVID-19 - study
2 years, 11 months ago

T-cells from common colds can provide protection against COVID-19 - study

Live Mint  

High levels of T-cells from common cold coronaviruses can provide protection against COVID-19, an Imperial College London study published on Monday has found, which could inform approaches for second-generation vaccines. Immunity against COVID-19 is a complex picture, and while there is evidence of waning antibody levels six months after vaccination, T-cells are also believed to play a vital role in …

Scientist develop new protein-based Covid vaccine that doesn't need cold storage
3 years, 1 month ago

Scientist develop new protein-based Covid vaccine that doesn't need cold storage

Hindustan Times  

Scientists have developed a new protein-based vaccine candidate for COVID-19 that they say is much easier to produce and does not need refrigeration. The research team at Boston Children's Hospital, US, noted that currently available Covid vaccines require cold storage and sophisticated manufacturing capacity, which makes it difficult to produce and distribute them widely, especially in less developed countries. The …

The Race Is On to Develop a Vaccine Against Every Coronavirus
3 years, 1 month ago

The Race Is On to Develop a Vaccine Against Every Coronavirus

Wired  

On October 21, the Centers for Disease Control and Prevention gave most of the US population permission to get a Covid vaccine booster—a shot in such high demand that 10 million people somehow obtained it in advance of that approval in an effort to feel a little safer. In a fistful of papers and preprints published in the past six …

Covid-19 vaccines may protect against other coronaviruses: Study
3 years, 2 months ago

Covid-19 vaccines may protect against other coronaviruses: Study

India Today  

Covid-19 vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses, according to a study. The study found that plasma from humans who had been vaccinated against SARS-CoV-2 produced antibodies that were cross-reactive, or provided protection, against SARS-CoV-1 and the common cold coronavirus. Mice that had been immunised with Covid-19 vaccines and later were exposed to the …

SARS-CoV-2 antibodies remain stable, even increase 7 months after infection: Study
3 years, 4 months ago

SARS-CoV-2 antibodies remain stable, even increase 7 months after infection: Study

Deccan Chronicle  

Barcelona: According to a recent study in a cohort of healthcare workers, the levels of IgG antibodies against SARS-CoV-2 Spike protein remained stable, or even increased, seven months after the infection. The results, published in the journal 'Nature Communications', also supported the idea that pre-existing antibodies against common cold coronaviruses could protect against COVID-19. With this goal in mind, the …

Potent, Stable Antibodies to Block SARS-CoV-2, Variants Developed
3 years, 4 months ago

Potent, Stable Antibodies to Block SARS-CoV-2, Variants Developed

News 18  

Researchers have developed highly potent and stable antibodies from the blood of alpacas which can efficiently block SARS-CoV-2, the virus that causes COVID-19, and its dangerous new variants. The researchers from the Max Planck Institute for Biophysical Chemistry in Germany noted that these mini-antibodies bind and neutralise the virus up to 1,000 times better than previously developed such antibodies. “For …

New universal coronavirus vaccine may help prevent future pandemics
3 years, 6 months ago

New universal coronavirus vaccine may help prevent future pandemics

India TV News  

Scientists have developed a universal vaccine that protected mice not just against COVID-19 but also other coronaviruses while triggering the immune system to fight off a dangerous variant. To prevent a future coronavirus pandemic, the team designed the vaccine to provide protection from the current SARS-CoV-2 coronavirus and a group of coronaviruses known to make the jump from animals to …

Coronavirus variants can evade antibodies by spreading via super-cells: Study
3 years, 6 months ago

Coronavirus variants can evade antibodies by spreading via super-cells: Study

India Today  

The antibodies we create after we’re infected with a virus or vaccinated against it can be very powerful. A virus typically spreads within our bodies by entering a cell and using it as a factory to create copies of itself, which then burst out and find new cells to infect. The study by Alex Sigal and colleagues tested two coronavirus …

Nasal spray designed from engineered antibody could treat Covid-19, boost efficacy: Report
3 years, 6 months ago

Nasal spray designed from engineered antibody could treat Covid-19, boost efficacy: Report

India Today  

As the second wave of Covid-19 recedes, countries are rushing to vaccinate their people to protect vulnerable groups with some experts anticipating a third wave of the pandemic. A study published in journal Nature stated that nasal spray of a designer antibody offers strong protection against variants of coronavirus in mice. The engineered antibody managed to reduce the amount of …

Vaccines boost natural immunity against Covid-19: Study
3 years, 6 months ago

Vaccines boost natural immunity against Covid-19: Study

India Today  

Vaccination boosts the natural immunity in people infected with the novel coronavirus so much that they are likely to be protected even from the emerging variants, according to a study. Data from their follow-ups show that, over time, antibodies produced by the immune system's memory B cells got better at neutralising SARS-CoV-2, the virus that causes Covid-19. READ: Second dose …

Unique Antibody Produced During Common Cold Reacts to Covid-19 Infection, Study Reveals
3 years, 6 months ago

Unique Antibody Produced During Common Cold Reacts to Covid-19 Infection, Study Reveals

News 18  

US researchers have identified that a special type of antibody is produced in patients who’ve had Covid-19 as well as common colds, an advance that may be the starting point for broader-acting vaccines. The study, by a team from the Scripps Research Institute, found that the cross-reactive antibody is produced by a memory B cell — an essential part of …

COVID19: Antibody from common cold reacts to infection, says researchers
3 years, 6 months ago

COVID19: Antibody from common cold reacts to infection, says researchers

India TV News  

US researchers have identified that a special type of antibody is produced in patients who've had Covid-19 as well as common colds, an advance that may be the starting point for broader-acting vaccines. The study, by a team from the Scripps Research Institute, found that the cross-reactive antibody is produced by a memory B cell -- an essential part of …

Coronavirus variants from Brazil, South Africa are less susceptible to antibodies, says study
3 years, 8 months ago

Coronavirus variants from Brazil, South Africa are less susceptible to antibodies, says study

India TV News  

Variant forms of the novel coronavirus which were first reported in South Africa and Brazil are less efficiently inhibited by antibodies from recovered patients and vaccinated individuals, a new study confirms. "This is worrisome because the rapid spread of variants that might not be efficiently inhibited by antibodies could undermine our current vaccination strategy," said Stefan Pohlmann, a co-author of …

Covid-19 Vaccine-induced Antibodies Less Effective Against Some Coronavirus Variants: Study
3 years, 9 months ago

Covid-19 Vaccine-induced Antibodies Less Effective Against Some Coronavirus Variants: Study

News 18  

Antibodies raised by some COVID-19 vaccines are less effective at neutralising new, circulating variants of the novel coronavirus such as the ones first reported in the UK, South Africa and Brazil, according to a new study. The research, published in the journal Cell, noted that the neutralising antibodies induced by the Pfizer and Moderna COVID-19 vaccines were less effective against …

World is in need of a universal coronavirus vaccine, warn scientists
3 years, 10 months ago

World is in need of a universal coronavirus vaccine, warn scientists

Firstpost  

The prestigious journal Science on Thursday published an editorial calling for a global effort to develop a universal coronavirus vaccine that would remain effective against other members of the same virus family that might cross over to humans. “Modern agricultural practices, viral evolution, and relentless human encroachment on the natural environment mean there is an increased risk of people encountering …

Immune system of recovered COVID-19 patients may evolve to fight coronavirus variants: Study
3 years, 11 months ago

Immune system of recovered COVID-19 patients may evolve to fight coronavirus variants: Study

The Hindu  

People who recover from COVID-19 are protected against the novel coronavirus for at least six months, and likely much longer, according to a study which says the immune system evolves long after the infection and may block even mutant forms of the virus. According to the scientists, including those from Rockefeller University in the U.S., the study provides the "strongest …

COVID-19 immunity lasts for six months, longer after infection finds new study
3 years, 11 months ago

COVID-19 immunity lasts for six months, longer after infection finds new study

Firstpost  

People who recover from COVID-19 are protected against the novel coronavirus for at least six months, and likely much longer, according to a study which says the immune system evolves long after the infection and may block even mutant forms of the virus such as the South African variant. Since the novel coronavirus replicates in the cells of the lungs, …

Coronavirus vaccine: Lancet study suggests Sinovac candidate is safe and effective in phase I and II trials
4 years, 1 month ago

Coronavirus vaccine: Lancet study suggests Sinovac candidate is safe and effective in phase I and II trials

Firstpost  

CoronaVac is an inactivated vaccine that had earlier shown positive results in mice, primates and rats by producing neutralising antibodies against SARS-CoV-2 It’s been almost a year now since the first case of COVID-19 was reported in Wuhan, China and, in all likelihood, no vaccine before this would have had a faster development. The results In phase I, from the …

Coronavirus immunity can last more than six months, study suggests
4 years, 1 month ago

Coronavirus immunity can last more than six months, study suggests

CNN  

CNN — Early research suggests immunity to the coronavirus that causes Covid-19 can last for at least six months – and possibly much longer, perhaps even years, when all components of the body’s immune memory are taken into consideration. “B cell memory to some other infections has been observed to be long-lived, including 60+ years after smallpox vaccination, or 90+ …

Pre-existing antibodies may protect some people against novel coronavirus, says study
4 years, 1 month ago

Pre-existing antibodies may protect some people against novel coronavirus, says study

India TV News  

Scientists have found that some antibodies, created by the immune system during infection with common cold coronaviruses, can also target the COVID-19 causing SARS-CoV-2, and may confer a degree of protection against the new virus. "Our results show that children are much more likely to have these cross-reactive antibodies than adults," said Kevin Ng, lead author of the study from …

Coronavirus vaccine: Oxford trial is ‘safe’ and produces immune reaction, first study results show
4 years, 5 months ago

Coronavirus vaccine: Oxford trial is ‘safe’ and produces immune reaction, first study results show

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Please enter a valid email address Please enter a valid email address SIGN UP I would like to be emailed about offers, events and updates from The Independent. Please try again later {{ /verifyErrors }} The coronavirus …

Potent SARS-CoV-2 neutralising antibody gene IGHV3-53 may help develop COVID-19 vaccine
4 years, 5 months ago

Potent SARS-CoV-2 neutralising antibody gene IGHV3-53 may help develop COVID-19 vaccine

Firstpost  

The outer layer of the SARS-CoV-2 virus contains a spike protein, also called S protein which helps the virus bind to the ACE-2 receptor cells More than 13 million people have been infected with COVID-19 infection across the globe, of which over seven million people have recovered. How antibodies work against the novel coronavirus The outer layer of the SARS-CoV-2 …

Forget antibodies, scientists look towards T-cells in the immune system to fight Coronavirus infection
4 years, 5 months ago

Forget antibodies, scientists look towards T-cells in the immune system to fight Coronavirus infection

Firstpost  

There is evidence that T-cells developed after exposure to other coronaviruses that cause the common cold could help fight off SARS-CoV-2. “There is mounting evidence that people exposed to the virus have a transient antibody response, or have a T cell response in spite of a minor or absent antibody response,” Dr Alessandro Sette, professor and member of the La …

Antibodies acquired after coronavirus infection won't be effective for very long: Study
4 years, 6 months ago

Antibodies acquired after coronavirus infection won't be effective for very long: Study

Firstpost  

The results offer a strong note of caution against the idea of ‘immunity certificates’ for people who have recovered from COVID-19. Antibodies — protective proteins made in response to an infection — may last only two to three months, especially in people who never showed symptoms while they were infected. Several studies have now shown that most people who are …

Antibodies against coronavirus start to decrease in 2-3 months, study finds
4 years, 6 months ago

Antibodies against coronavirus start to decrease in 2-3 months, study finds

The Hindu  

A few countries, including the U.K., were toying with the idea of issuing some form of a certificate to people who have been infected with novel coronavirus and recovered subsequently, as such people were assumed to be resistant to reinfection. “We observed that IgG levels and neutralizing antibodies in a high proportion of individuals who recovered from SARS-CoV-2 infection start …

Antibodies from recovered COVID-19 patients show powerful protection against SARS-CoV-2 infection
4 years, 6 months ago

Antibodies from recovered COVID-19 patients show powerful protection against SARS-CoV-2 infection

Firstpost  

Scientists have long suspected that antibodies in the blood of COVID-19 patients that have successfully fought the infection and recovered could provide powerful protection against SARS-CoV-2 – the coronavirus that causes COVID-19. “The discovery of these very potent antibodies represents an extremely rapid response to a totally new pathogen,” co-senior author Dennis Burton, the James and Jessie Minor Chair in …

Nearly 160 coronavirus vaccines are in the works. Here’s a closer look at the science
4 years, 6 months ago

Nearly 160 coronavirus vaccines are in the works. Here’s a closer look at the science

LA Times  

Vials used to prepare syringes in a safety study of a potential coronavirus vaccine developed by the National Institutes of Health and Moderna Inc. Live attenuated virus vaccine Developed in 1937 by virologist Max Theiler to create a yellow fever vaccine, this protocol takes a live virus and introduces it to mice, chicken embryos or other non-human species. Because the …

Coronavirus: New vaccine in development using decades-old methods
4 years, 6 months ago

Coronavirus: New vaccine in development using decades-old methods

NL Times  

A team at Amsterdam UMC are using vaccines developed in 1927 to try to coax the human immune system into attacking the novel coronavirus SARS-CoV-2. According to the medical center, the new vaccine is aimed at producing antibodies which attach to protein protrusions, or spikes, present on each individual virion. The research team, which is working in collaboration with biotech …

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