Why the coronavirus variant in South Africa has put a damper on vaccines – and why many are still hopeful
4 years, 1 month ago

Why the coronavirus variant in South Africa has put a damper on vaccines – and why many are still hopeful

CNN  

CNN — A roller coaster of research has stoked concerns that a coronavirus variant first linked to South Africa could be resistant to vaccines and raise the bar for herd immunity. On Sunday, health officials in South Africa announced a temporary hold on the rollout of the Oxford/AstraZeneca vaccine after a study suggested it offered “minimal protection” against mild-to-moderate Covid-19 due to the variant, the University of Oxford said. “Across all geographies, across all variants, we see 85% protection” against severe disease, Dr. Mathai Mammen, the company’s global head of research and development, previously told CNN. Oxford’s announcement this week said that neutralization activity against B.1.351 was “substantially reduced when compared with the original strain of the coronavirus.” Similar results have been seen, albeit to varying degrees, across “almost every one of the vaccines that have been studied against this variant in different ways, either in the laboratory or in clinical studies,” Dr. Salim Abdool Karim, the chair of the South African government’s coronavirus advisory panel, previously told CNN. “When you look at the studies done in labs, there was less neutralizing activity against the South Africa strain,” vaccine expert Dr. Paul Offit told CNN after Novavax and Johnson & Johnson shared their results.

History of this topic

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