Fourth shot of Covid vaccine is NOT enough to prevent 'lots of infections' from Omicron
2 years, 11 months ago

Fourth shot of Covid vaccine is NOT enough to prevent 'lots of infections' from Omicron

Daily Mail  

Even a fourth dose of a Covid vaccine isn't enough to stop people getting infected with Omicron, according to the preliminary results of a trial. The fourth dose of the Covid vaccine is less effective on the Omicron variant and provides only limited defence, a preliminary study in Israel has found Israel was the first country in the world to roll out boosters last year and became one of the only nations in the world to start dishing out fourth jabs last month to combat Omicron. UK EXTENDS PFIZER'S SHELF LIFE AMID SLOWING BOOSTER ROLLOUT Health chiefs in the UK have extended the shelf life of Pfizer's Covid jabs over fears millions of injections would have to be binned. Professor Andrew Hayward, a member of the UK Government's Scientific Advisory Group for Emergencies, said Covid jabs should be rolled out like flu vaccines in the future.

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History of this topic

A German man who received 217 COVID vaccinations becomes focus of new immunisation research
9 months, 2 weeks ago

A German man who received 217 COVID vaccinations becomes focus of new immunisation research

ABC  

In short: German researchers have studied the immune response of a 62-year-old man who they say had received more than 200 COVID shots for "private reasons" within the space of 29 months. German researchers have studied the immune response of a 62-year-old man who they say had received more than 200 COVID shots for "private reasons" within the space of …

Nearly 10,000 died from COVID-19 last month, fueled by holiday gatherings and new variant, WHO says
11 months, 2 weeks ago

Nearly 10,000 died from COVID-19 last month, fueled by holiday gatherings and new variant, WHO says

Associated Press  

GENEVA — The head of the U.N. health agency said Wednesday holiday gatherings and the spread of the most prominent variant globally led to increased transmission of COVID-19 last month. Tedros Adhanom Ghebreyesus said nearly 10,000 deaths were reported in December, while hospital admissions during the month jumped 42% in nearly 50 countries — mostly in Europe and the Americas …

New COVID-19 vaccines available in Australia: Millions urged to get a booster as cases rise
1 year ago

New COVID-19 vaccines available in Australia: Millions urged to get a booster as cases rise

Daily Mail  

New COVID-19 vaccines targeting the current Omicron variant of the virus are available in community pharmacies throughout Australia. Pharmacy Guild of Australia National President Trent Twomey says the new vaccine available on Monday is targeted at the strain of the virus which is currently circulating among the population. 'With COVID-19 cases on the rise, it is important anyone who is …

Next round of COVID-19 shots in fall will target latest omicron strain
1 year, 6 months ago

Next round of COVID-19 shots in fall will target latest omicron strain

Associated Press  

NEW YORK — The next round of COVID-19 vaccines will target one of the latest versions of the coronavirus, the Food and Drug Administration said Friday. The agency told vaccine makers to provide protection against just one omicron strain, known as XBB.1.5. The three U.S. companies that make COVID-19 shots said this week they had geared up to make the …

FDA advisers endorse updating COVID vaccines to target latest omicron strain
1 year, 6 months ago

FDA advisers endorse updating COVID vaccines to target latest omicron strain

Associated Press  

The COVID-19 vaccines are on track for a big recipe change this fall. Today’s vaccines still contain the original coronavirus strain, the one that started the pandemic — even though that was long ago supplanted by mutated versions as the virus rapidly evolves. While infections have declined, the virus could be a real concern next winter, FDA’s vaccine chief Dr. …

FDA advisers back updated COVID shots for fall vaccinations
1 year, 6 months ago

FDA advisers back updated COVID shots for fall vaccinations

NPR  

FDA advisers back updated COVID shots for fall vaccinations Enlarge this image toggle caption Esteban Felix/AP Esteban Felix/AP A panel of expert advisers to the Food and Drug Administration voted unanimously Thursday to recommend that the COVID-19 vaccine be updated to target emerging subvariants of omicron. The COVID shot that's currently available is known as a "bivalent" vaccine because it …

COVID fourth dose might not work if…, expert on how to tackle new variant surge
1 year, 8 months ago

COVID fourth dose might not work if…, expert on how to tackle new variant surge

Live Mint  

The COVID-19 pandemic has brought about many challenges, one of which is the emergence of new variants of the virus that can evade immunity conferred by existing vaccines. While booster doses can still reduce the severity of the disease, experts are of the opinion that it may be time for governments to start thinking about second-generation vaccines. And, one of …

CDC signs off on additional Covid-19 booster doses for certain people
1 year, 8 months ago

CDC signs off on additional Covid-19 booster doses for certain people

CNN  

CNN — The US Centers for Disease Control and Prevention updated its recommendations on the Covid-19 vaccines on Wednesday to allow another dose of the bivalent booster for people who are 65 and older or who have weakened immune systems and who “want the option of added protection” against the coronavirus. The move aligns with Tuesday’s US Food and Drug …

‘Study on covid vaccines’ efficacy soon’
1 year, 8 months ago

‘Study on covid vaccines’ efficacy soon’

Live Mint  

New Delhi: The National Institute of Virology plans to conduct a study to determine the efficacy of vaccines with covid variants. Asked if there’s a need for a 4th dose, Yadav said in an interview, “Before we talk about 4th dose, we should enhance coverage of 3rd precautionary dose to enhance the immune response.” Only about 228.7 million Indians have …

Australian adults will be able to get fifth dose of COVID-19 vaccine later this month
1 year, 10 months ago

Australian adults will be able to get fifth dose of COVID-19 vaccine later this month

ABC  

Australian adults will be able to get a fifth dose of the COVID-19 vaccine within a fortnight, after the federal government accepted advice from its expert vaccine advisory body. Key points: From February 20, people 18 and over who have not had a COVID-19 vaccine or positive case in the last six months are eligible for another shot Uptake of …

No need for fourth dose of COVID-19 vaccine given current evidence, says Dr Raman Gangakhedkar
1 year, 11 months ago

No need for fourth dose of COVID-19 vaccine given current evidence, says Dr Raman Gangakhedkar

Firstpost  

Pune: Dr Raman Gangakhedkar, former head of epidemiology and communicable diseases at the Indian Council of Medical Research, on Tuesday, discounted the need to take the fourth dose of COVID-19 vaccine given the current evidence regarding the coronavirus and variants. “Looking at the current evidence, it is not that big that there is any need for the fourth dose of …

4th COVID vaccine not needed: Expert
1 year, 11 months ago

4th COVID vaccine not needed: Expert

Live Mint  

Given the available information regarding the coronavirus and its variants, Dr. Raman Gangakhedkar, the former director of epidemiology and communicable diseases at the Indian Council of Medical Research, has questioned the need for the fourth dose of the COVID-19 vaccine. Dr. Gangakhedkar noted on the sidelines of a function on January 24 that, if a person received a third dosage …

Fourth Covid vaccine unwarranted right now but increased surveillance needed: experts
1 year, 11 months ago

Fourth Covid vaccine unwarranted right now but increased surveillance needed: experts

Deccan Chronicle  

NEW DELHI: Several countries are administering a third and even fourth Covid booster shot but India, where many fully vaccinated individuals have not taken even one, is not there yet, say experts while stressing on the need for a structured and systematic response. If that infection did not trigger enough Omicron-specific immunity none of the vaccines currently available in India …

Omicron BF.7: Is mixing Covid vaccines more effective against the new subvariant? What experts say
2 years ago

Omicron BF.7: Is mixing Covid vaccines more effective against the new subvariant? What experts say

Hindustan Times  

Amid rising cases of Omicron BF.7 in China and other parts of the world, there has been concerns of a fresh wave triggered by the subvariant in India in the coming months. However, mixing the vaccines has no side effects rather it can boost the immunity and give multiple ways to our immune system to identify the offending virus and …

COVID-19: no need for scaremongering, precautions needed, say health experts
2 years ago

COVID-19: no need for scaremongering, precautions needed, say health experts

The Hindu  

Even as the Central and State governments have called for a general alert over a possible rise in COVID-19 cases, public health experts have warned against scaremongering over COVID-19. Public health experts point out that as the new virus variants coming into circulation are the sub variants of Omicron, which in itself was less lethal than Delta, there was no …

Op-Ed: You might need a COVID booster yearly. But this virus is still nothing like the flu
2 years, 3 months ago

Op-Ed: You might need a COVID booster yearly. But this virus is still nothing like the flu

LA Times  

Should everyone eligible get the new Omicron-specific COVID booster? In San Francisco, when talking to families of vaccinated individuals who died, I’ve often learned that the patient rushed to get their first two shots after the vaccine was authorized in December 2020 but had not received a booster despite third shots being greenlit last fall. Even with increased population immunity, …

Can you catch Covid twice? How likely you are to catch the virus again
2 years, 3 months ago

Can you catch Covid twice? How likely you are to catch the virus again

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Danny Altmann, a professor of immunology at Imperial College London, told The Guardian, Omicron is …

UK approves second 'bivalent' booster for Omicron, original COVID strain
2 years, 3 months ago

UK approves second 'bivalent' booster for Omicron, original COVID strain

India Today  

The UK health authorities on Saturday approved a second “bivalent” vaccine to be used as a booster vaccine to target both the Omicron and the original strain of COVID-19. In each dose of the booster vaccine called “Comirnaty bivalent Original/Omicron”, half of the vaccine targets the original virus strain and the other half targets Omicron. “The clinical trial of the …

Omicron-specific boosters are here: How effective will these vaccines be in the fight against COVID-19?
2 years, 3 months ago

Omicron-specific boosters are here: How effective will these vaccines be in the fight against COVID-19?

Firstpost  

The new booster shots — one by Moderna and another from Pfizer-BioNTech – are specifically tailored to combat the two most recent and contagious Omicron subvariants, BA4 and BA5 On 31 August 2022, the Food and Drug Administration authorised the use of updated COVID-19 booster shots that are specifically tailored to combat the two most recent and contagious Omicron subvariants, …

US CDC endorses updated Covid boosters, shots to begin soon
2 years, 3 months ago

US CDC endorses updated Covid boosters, shots to begin soon

India Today  

The US Centers for Disease Control and Prevention on Thursday endorsed updated Covid-19 boosters, opening the way for a fall vaccination campaign that could blunt a winter surge if enough Americans roll up their sleeves. The CDC’s advisers struggled with who should get the new boosters and when because only a similarly tweaked vaccine, not the exact recipe, has been …

CDC endorses updated COVID boosters, shots to begin soon
2 years, 3 months ago

CDC endorses updated COVID boosters, shots to begin soon

Associated Press  

The Centers for Disease Control and Prevention on Thursday endorsed updated COIVD-19 boosters, opening the way for a fall vaccination campaign that could blunt a winter surge if enough Americans roll up their sleeves. “I think they’re going to be an effective tool for disease prevention this fall and into the winter,” said CDC adviser Dr. Matthew Daley of Kaiser …

CDC Recommends Updated COVID-19 Vaccine Boosters Targeting Omicron Strains
2 years, 3 months ago

CDC Recommends Updated COVID-19 Vaccine Boosters Targeting Omicron Strains

Huff Post  

LOADING ERROR LOADING New COVID-19 boosters that target today’s most common omicron strains are set to begin soon after the Centers for Disease Control and Prevention endorsed the updated shots Thursday. The decision by CDC Director Rochelle Walensky came shortly after the agency’s advisers said if enough people roll up their sleeves, the shots could blunt a winter surge. The …

EU regulator clears tweaked versions of COVID vaccines
2 years, 3 months ago

EU regulator clears tweaked versions of COVID vaccines

Associated Press  

LONDON — The European Medicines Agency has recommended the authorization of two coronavirus vaccines made by Pfizer-BioNTech and Moderna Inc., tweaked to include protection against an early version of the omicron variant. In a statement on Thursday, the EU drug regulator said the two messenger RNA boosters offered protection both against the original version of COVID-19 and the omicron subvariant …

EMA approves updated Pfizer, Moderna Covid vaccines to fight Omicron variant
2 years, 3 months ago

EMA approves updated Pfizer, Moderna Covid vaccines to fight Omicron variant

NL Times  

The European Medicines Agency gave a positive recommendation to authorize the modified versions of the Covid-19 vaccines from Pfizer/BioNTech and Moderna, which should provide better protect against the Omicron variant of the virus, the European Union's medicines watchdog said on Thursday. The committee judged that the modified vaccines provide a strong immune response against both the original variant, and the …

U.S. authorizes updated COVID-19 boosters targeting newest variants
2 years, 3 months ago

U.S. authorizes updated COVID-19 boosters targeting newest variants

LA Times  

The U.S. on Wednesday authorized its first update to COVID-19 vaccines, booster doses that target today’s most common Omicron strains. “Give a clear, forward-looking set of expectations.” Here’s the rub: The original vaccines still offer strong protection against severe disease and death from COVID-19 for most generally healthy people, especially if they got that important first booster dose. First, FDA …

US approves updated COVID boosters targeting Omicron variants
2 years, 3 months ago

US approves updated COVID boosters targeting Omicron variants

Al Jazeera  

Drugmaker Pfizer said it has doses ready to ship and can deliver up to 15 million shots by the end of next week. The United States has authorised booster doses of the COVID-19 vaccines that target the most common Omicron strain, and shots could be available within days. “You’ll see me at the front of the line,” FDA vaccine chief …

Tweaked COVID boosters are close, but how much will they help?
2 years, 4 months ago

Tweaked COVID boosters are close, but how much will they help?

LA Times  

Pre-loaded syringes are ready for use at a school in New Orleans. Dr. Peter Marks, the FDA’s vaccine chief, said Thursday that once authorized, the tweaked boosters could help right away — while BA.5 infections still are too high — and hopefully blunt yet another winter surge. To evaluate the combo shots, the FDA is using data from human testing …

Pfizer COVID vaccine 73% effective in children aged between 6 months and 4 years
2 years, 4 months ago

Pfizer COVID vaccine 73% effective in children aged between 6 months and 4 years

Live Mint  

Pfizer said that its COVID vaccine is 73.2% effective in the age group of 6 months to 4 years. The updated data released on Tuesday showed 13 children had COVID-19, at least seven days after receiving a third dose of the Pfizer-BioNTech COVID-19 vaccine, compared with 21 cases in those who received a placebo. The companies also said they were …

Pfizer seeks OK of COVID booster that targets Omicron
2 years, 4 months ago

Pfizer seeks OK of COVID booster that targets Omicron

LA Times  

A health worker administers a dose of Pfizer’s Comirnaty COVID-19 vaccine in Reading, Pa. Pfizer has asked U.S. regulators to authorize its combination COVID-19 shot that adds protection against Omicron subvariants. Pfizer asked U.S. regulators Monday to authorize its combination COVID-19 vaccine that adds protection against Omicron subvariants, a key step toward opening a fall booster campaign. The U.S. has …

WHO expert on hurdle in tracking new variants, reducing risk of long Covid
2 years, 4 months ago

WHO expert on hurdle in tracking new variants, reducing risk of long Covid

Hindustan Times  

The World Health Organization has been facing hurdles in tracking known and detecting new coronavirus variants amid reduced surveillance, testing and sequencing globally, a top expert has said days after WHO chief Dr Tedros Adhanom Ghebreyesus warned that “living with Covid” does not mean “living with mounting deaths”. As of August 14, the world health body had registered 587 million …

As Australia passes another COVID peak, what comes after Omicron remains a mystery
2 years, 4 months ago

As Australia passes another COVID peak, what comes after Omicron remains a mystery

ABC  

Omicron has dominated COVID-19 cases since it was detected last November, but scientists say it's unlikely to be the last variant we grapple with. "I would like to think that as the level of general immunity across the globe increases just through vaccination and infection, that that basic level of immunity would still mean that we're less likely to have …

White House urges caution on COVID variants, pushes boosters
2 years, 5 months ago

White House urges caution on COVID variants, pushes boosters

Associated Press  

WASHINGTON — The Biden administration is calling on people to exercise renewed caution about COVID-19, emphasizing the importance of getting booster shots for those who are eligible and wearing masks indoors as two new highly transmissible variants are spreading rapidly across the country. “If you’re over 50 and you haven’t gotten the shot this year, you should go get a …

Will Americans have the right COVID-19 vaccine this fall? Maybe
2 years, 5 months ago

Will Americans have the right COVID-19 vaccine this fall? Maybe

LA Times  

A man walks underneath the marquee of the Alex Theatre in Glendale. Determining which recipe should go into those doses to induce optimal protection — the vaccine’s “composition” — is an exercise in educated guesswork. Getting a timely and accurate fix on all this “is truly a challenge, and it is science at its hardest,” Dr. Peter Marks, the U.S. …

Experts say there are a number of factors to weigh up about getting a fourth dose of a COVID-19
2 years, 5 months ago

Experts say there are a number of factors to weigh up about getting a fourth dose of a COVID-19

ABC  

Another 7.5 million Australians are becoming eligible for a fourth COVID-19 vaccine as new Omicron sub-variants drive higher case numbers and hospitalisations around the country. "There's going to be a lot of transmission over winter and there's going to be a lot of hospitalisation, so I would say, on balance, get vaccinated now if you're concerned," Dr Trauer said. Nathan …

COVID-19 fourth-dose boosters offered for all people over 30
2 years, 5 months ago

COVID-19 fourth-dose boosters offered for all people over 30

ABC  

The nation's expert vaccine advisory body has recommended that anyone older than 50 receive a fourth dose of the COVID-19 vaccine. Key points: ATAGI has recommended people over 50 receive a fourth dose of the COVID vaccine ATAGI has recommended people over 50 receive a fourth dose of the COVID vaccine People aged 30 to 49 may choose to have …

Can new Omicron subvariants evade vaccine immunity?
2 years, 5 months ago

Can new Omicron subvariants evade vaccine immunity?

Al Jazeera  

Dr Khan on why COVID cases are rising and what we know about how past infections and vaccines interact with Omicron BA.4 and BA.5. The uptick in new COVID cases and hospital admissions is thought to be driven largely by new subvariants of the Omicron variant of SARS-CoV-2, known as BA.4 and BA.5. The European Centre for Disease Prevention and …

Tweaked COVID boosters in US must target newer omicron types
2 years, 5 months ago

Tweaked COVID boosters in US must target newer omicron types

Associated Press  

U.S. regulators told COVID-19 vaccine makers Thursday that any booster shots tweaked for the fall will have to add protection against the newest omicron relatives. And the current Pfizer and Moderna vaccines still offer strong protection against COVID-19’s worst outcomes as long as people have gotten already recommended boosters. The FDA’s decision comes after its scientific advisers earlier this week …

FDA advisers recommend updating COVID booster shots for fall
2 years, 5 months ago

FDA advisers recommend updating COVID booster shots for fall

Associated Press  

At least some U.S. adults may get updated COVID-19 shots this fall, as government advisers voted Tuesday that it’s time to tweak booster doses to better match the most recent virus variants. Their combination shots, what scientists call “bivalent” vaccines, substantially boosted levels of antibodies capable of fighting that variant, more than simply giving another dose of today’s vaccine. Marks …

FDA advisors recommend updating COVID booster shot formula for fall
2 years, 5 months ago

FDA advisors recommend updating COVID booster shot formula for fall

LA Times  

Advisors to the Food and Drug Administration are recommending that some U.S. adults get a modified COVID-19 booster shot this fall that better matches the recent variants. Some U.S. adults are a step closer to getting updated COVID-19 boosters this fall, as government advisors voted Tuesday that it’s time to tweak the shots to better match the most recent virus …

When Will It Be Time For Another COVID Booster? Here's What Experts Think.
2 years, 6 months ago

When Will It Be Time For Another COVID Booster? Here's What Experts Think.

Huff Post  

LOADING ERROR LOADING We’ve seen second COVID-19 boosters recommended for older adults and people with underlying health conditions — but what about the general population? Immunocompromised individuals and older people’s antibody levels wane earlier, which makes these people strong candidates for booster doses, said Arjun Venkatesh, a Yale Medicine emergency medicine doctor and associate professor at Yale School of Medicine. …

Covid Vaccines For Children Under-Five Received US FDA Nod
2 years, 6 months ago

Covid Vaccines For Children Under-Five Received US FDA Nod

News 18  

A panel of experts convened by the US Food and Drug Administration unanimously recommended Covid-19 vaccines Wednesday for children under five, the final age group awaiting immunization in most countries. Opening the discussion, senior FDA scientist Peter Marks said that despite studies showing the majority of children have now been infected with the coronavirus, the high rate of hospitalizations among …

Moderna says updated COVID shot boosts omicron protection
2 years, 6 months ago

Moderna says updated COVID shot boosts omicron protection

Associated Press  

Moderna’s experimental COVID-19 vaccine that combines its original shot with protection against the omicron variant appears to work, the company announced Wednesday. Moderna’s preliminary study results show people given the combination shot experienced a higher boost in omicron-fighting antibodies than if they just got a fourth dose of the original vaccine. They’re still providing strong protection against severe disease, hospitalization …

Omicron infection better at upping immunity than boosters, claims study
2 years, 7 months ago

Omicron infection better at upping immunity than boosters, claims study

India Today  

As coronavirus continues to infect people across the world, the latest trends in India show that hospitalisation rates are very low and the recovery is faster. A new study now reveals that Omicron infections produced even better immune responses than a booster shot in vaccinated people. The study conducted by vaccine maker BioNTech SE and the University of Washington reassures …

Fourth Covid-19 vaccine dose provides strong immunity boost: UK study
2 years, 7 months ago

Fourth Covid-19 vaccine dose provides strong immunity boost: UK study

India TV News  

A fourth dose of the Pfizer or Moderna COVID-19 vaccine is safe and boosts antibody levels, even higher than that of a third dose, according to the latest results from a nationwide study in the UK. The findings, published in The Lancet Infectious Disease journal, show that fourth dose mRNA booster vaccines for COVID-19 are well-tolerated in people who received …

Low Number of Covid-19 Cases Now as India Chose Right Vaccine, Says Serum Institute's Poonawalla
2 years, 8 months ago

Low Number of Covid-19 Cases Now as India Chose Right Vaccine, Says Serum Institute's Poonawalla

News 18  

Serum Institute of India CEO Adar Poonawalla on Monday said the low number of COVID-19 cases at the moment was because the country chose the right vaccine. They are having internal discussions and a policy on booster dose may be announced soon.” All other countries are doing it and it was now time for India to have a look at …

Fourth COVID-19 vaccine shots are available, but only for certain groups of people. Here's who is eligible
2 years, 8 months ago

Fourth COVID-19 vaccine shots are available, but only for certain groups of people. Here's who is eligible

ABC  

Some groups of people will be able to receive their fourth — and in some cases, their fifth — dose of a COVID-19 vaccination. The Australian Technical Advisory Group on Immunisation has recommended an additional vaccine dose for the following groups: Anyone aged 65 years and older People who live in aged care or disability care facilities People aged 16 …

Booster dose of COVID-19 vaccine needed to fight against Omicron, says study
2 years, 8 months ago

Booster dose of COVID-19 vaccine needed to fight against Omicron, says study

Firstpost  

New Delhi: Neutralising antibody levels waned after six months in those who were fully vaccinated against the coronavirus with Covishield, Covaxin and a mix of both — Covishield as the first dose and Covaxin as the second dose with regard to Omicron variant, a study done by the National Institute of Virology in Pune has indicated. The heterologous vaccination regimen …

Covid-19: US FDA approves another Pfizer, Moderna booster dose for age 50 and up
2 years, 8 months ago

Covid-19: US FDA approves another Pfizer, Moderna booster dose for age 50 and up

India Today  

US regulators on Tuesday authorized another COVID-19 booster for people age 50 and older, a step to offer extra protection for the most vulnerable in case the coronavirus rebounds. The Food and Drug Administration's decision opens a fourth dose of the Pfizer or Moderna vaccines to those people at least four months after their previous booster. Pfizer had asked the …

US regulators approve 2nd COVID booster for those aged 50 and up
2 years, 8 months ago

US regulators approve 2nd COVID booster for those aged 50 and up

Al Jazeera  

US has seen a small uptick in new COVID-19 cases during the past week, raising concern that infections could surge again. Regulators in the United States have authorised another COVID-19 booster shot for people aged 50 and older, amid concerns that coronavirus infections may begin rising again due to waning immunity to Omicron variants. “Based on an analysis of emerging …

'Perfect storm': Experts warn against removing Covid curbs across world
2 years, 9 months ago

'Perfect storm': Experts warn against removing Covid curbs across world

India Today  

Covid-19 is again surging in Western Europe due to a "perfect storm" of governments lifting restrictions, waning immunity and the more contagious BA.2 Omicron subvariant, experts said Monday. Lawrence Young, a virologist at Britain's University of Warwick, said the rising cases in Europe were due to a combination -- "a perfect storm" -- of three factors: the lifting of restrictions, …

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