49ers seek their 7th straight win against the Seahawks
Associated PressSeattle at San Francisco Sunday, 4:05 p.m. EST, Fox BetMGM NFL odds: 49ers by 6 1/2. 49ers player to watch QB Brock Purdy threw for 353 yards and two TDs last week against Tampa Bay and had his 13th career game with a rating of at least 115. Key injuries The Seahawks activated RT Abe Lucas off the PUP list this week, and he is expected to play for the first time since injuring his knee last season.. TEs Noah Fant and Brady Russell are also out for Seattle.. Seahawks C Connor Williams decided to retire this week and will be replaced in the lineup by Olu Oluwatimi.. San Francisco T Trent Williams, TE George Kittle and DE Nick Bosa are all questionable.. DE Yetur Gross-Matos is expected to return from IR this week for the 49ers.. Niners P Mitch Wishnowsky will miss the game and be replaced by Pat O’Donnell. The 49ers are second in the NFL in averaging 7.05 yards per play on first down.. San Francisco is second in the NFL with 45 plays from scrimmage for at least 20 yards and is tied for third best with 26 allowed.. San Francisco’s George Kittle leads all TEs with seven TD catches.. Niners RB Christian McCaffrey had 107 yards from scrimmage in his season debut last week. He had 39 yards rushing on 13 carries and caught six passes for 68 yards.. McCaffrey’s 56 games with at least 100 yards from scrimmage are tied with New Orleans’ Alvin Kamara for the most of any active player.. San Francisco K Jake Moody missed three FGs last week before kicking the game-winner from 44 yards on the final play.