Scientists identify antibodies that can block Omicron variant of Covid-19
3 years ago

Scientists identify antibodies that can block Omicron variant of Covid-19

India Today  

Scientists have identified antibodies that neutralise Omicron and other variants of coronavirus by targeting areas that remain essentially unchanged as the virus mutates. "This finding tells us that by focusing on antibodies that target these highly conserved sites on the spike protein, there is a way to overcome the virus' continual evolution," said David Veesler, an associate professor at the University of Washington School of Medicine in the US. The Omicron variant has an unusually high number of 37 mutations in the spike protein, which the virus uses to enter and infect the human cells. "The main questions we were trying to answer were: how has this constellation of mutations in the spike protein of the Omicron variant affected its ability to bind to cells and to evade the immune system's antibody responses," Veesler said. They found the Omicron variant spike protein was able to bind 2.4 times better than spike protein found in the virus isolated at the very beginning of the pandemic.

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