Why is it so difficult to lose weight? ‘Fat cells’ may be the reason

We all know how challenging it is to lose weight – countless hours of dieting and exercising. Studies suggest that even after weight loss, fat cells retain a “memory” of obesity. “But we don’t know.” Some genetic changes in human fat cells do not go away even after weight loss. Representational image/Pixabay Professor Henriette Kirchner, University of Lubeck, described the findings as “very plausible.” She told the UK daily, “I’m convinced it plays an important role in the yo-yo effect after dieting…The researchers show convincingly that the memory becomes harder to erase the longer you were obese.” Weight regain is common among individuals who lose weight through dieting or after using weight-loss treatments like Wegovy, especially when these interventions are stopped. The result is yo-yo dieting.” Understanding how fat cells retain the memory of obesity could pave the way for improved treatments, offering hope to millions struggling to manage their weight effectively.