Multivariant Covid vaccine booster shows promise, early data suggests
Deccan ChronicleLondon: A COVID-19 vaccine booster aimed at tackling multiple coronavirus variants shows promise in inducing a comprehensive immune response, early data suggests. The initial phase one clinical data shows the vaccine has strong levels of neutralising antibodies, similar to approved mRNA vaccines, but at up to a 10-fold lower dose in the first 10 individuals. "These initial data with samRNA Covid programme strongly support its unique approach of CD8+ T cell priming and potent neutralising antibody generation with a dose of samRNA potentially up to 10-fold lower than that required for first generation mRNA vaccines," said Professor Andrew Ustianowski from the University of Manchester. According to Allen, the vaccine will generate an immune state that may offer more robust clinical protection against current and future SARS-CoV-2 variants and be a first step towards developing a pan-coronavirus vaccine.