World's first CRISPR gene-edited babies claimed by Chinese researcher as success
6 years, 4 months ago

World's first CRISPR gene-edited babies claimed by Chinese researcher as success

Firstpost  

Society will decide what to do next in terms of allowing or forbidding such science: Researcher. It’s “unconscionable … an experiment on human beings that is not morally or ethically defensible,” said Dr Kiran Musunuru, a University of Pennsylvania gene editing expert and editor of a genetics journal. It’s a big deal.” However, one famed geneticist, Harvard University’s George Church, defended attempting gene editing for HIV, which he called “a major and growing public health threat.” “I think this is justifiable,” Church said of that goal. The study’s intended purpose The Chinese researcher said he practiced editing mice, monkey and human embryos in the lab for several years and has applied for patents on his methods. He sought and received approval for his project from Shenzhen Harmonicare Women’s and Children’s Hospital, which is not one of the four hospitals that He said provided embryos for his research or the pregnancy attempts.

China Research Gene Rice Editing Chinese Human Shenzhen Hiv Embryos Gene Editing Researcher Deem Chinese Researcher  twin  babies  china  geneedited  researcher  chinese  success  worlds  editing  claimed  embryos  research  human  pregnancy  called  gene  crispr  hiv

History of this topic

The controversial scientist He Jiankui hasn’t given up on gene-edited babies
1 month ago

The controversial scientist He Jiankui hasn’t given up on gene-edited babies

The Economist  

T he world was shocked in 2018 when He Jiankui, a Chinese biophysicist, announced that he had helped to produce two girls whose genetic code he had edited when they had been embryos. Scientists around the world condemned the work as wildly premature and possibly dangerous—the Chinese authorities agreed and Dr He was imprisoned for three years. And he still …

Ethical guideline issued for genome editing
8 months, 2 weeks ago

Ethical guideline issued for genome editing

China Daily  

China has issued a set of ethical rules on human genome editing, reiterating a strict ban on altering germ cells and embryos and clarifying standard ethical practices for gene editing research. "At present, any clinical research involving germline genome editing is irresponsible and not permitted," it said. Regarding clinical research involving genome editing of somatic cells — which are cells …

Guideline sets ethical rules for human genome editing research
8 months, 2 weeks ago

Guideline sets ethical rules for human genome editing research

China Daily  

China on Wednesday released a guideline that lays out a set of ethical rules for human genome editing research. Regarding clinical research involving genome editing of somatic cells — which are cells in the body other than sperm and egg cells, it said that such research should be aimed at preventing or treating diseases and should be carried out after …

Disgraced Chinese scientist He Jiankui who was jailed in 2019 for genetically editing human babies is back in the lab - and claims he's 'proud' of his past work
11 months, 3 weeks ago

Disgraced Chinese scientist He Jiankui who was jailed in 2019 for genetically editing human babies is back in the lab - and claims he's 'proud' of his past work

Daily Mail  

A disgraced Chinese scientist who was jailed for genetically editing human babies reveals he has returned to genetic research. He Jiankui has announced he has returned to the lab after being jailed for genetically editing human babies Dr He says that he intends to develop gene editing techniques for the treatment of rare diseases such as Duchenne muscular dystrophy and …

For man behind gene-edited babies, a rocky return to science
2 years ago

For man behind gene-edited babies, a rocky return to science

Associated Press  

Five years ago, scientist He Jiankui shocked his peers and the world with claims that he created the first genetically edited babies. Given He’s ambition,“I wouldn’t be surprised that a few years down the line if the opportunity arises, that he would go back” to that sort of work, said Dr. Samira Kiani, a genetic engineer and researcher at the …

Documentary spurs a new look at the case of the first gene-edited babies
2 years, 3 months ago

Documentary spurs a new look at the case of the first gene-edited babies

Salon  

In the four years since an experiment by disgraced scientist He Jiankui resulted in the birth of the first babies with edited genes, numerous articles, books and international commissions have reflected on whether and how heritable genome editing – that is, modifying genes that will be passed on to the next generation – should proceed. Creation of the 'CRISPR babies' …

A Bold Effort to Cure HIV—Using Crispr
2 years, 5 months ago

A Bold Effort to Cure HIV—Using Crispr

Wired  

In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to snip the AIDS-causing virus out of his cells. “What we’re trying to do is return the cell to a near-normal state,” says Daniel Dornbusch, CEO of Excision BioTherapeutics, the San Francisco-based biotech company that’s running the trial. “HIV is a …

CRISPR gene editing can cause unwanted changes in human embryos, study finds
4 years, 4 months ago

CRISPR gene editing can cause unwanted changes in human embryos, study finds

Firstpost  

Instead of addressing genetic mutations, the CRISPR-Cas9 technology appeared to wreak genetic havoc in about half the specimens that the researchers examined A powerful gene-editing tool called CRISPR-Cas9, which this month nabbed the Nobel Prize in Chemistry for two female scientists, can cause serious side effects in the cells of human embryos, prompting them to discard large chunks of their …

Lab tests show risks of using CRISPR gene editing on embryos
4 years, 4 months ago

Lab tests show risks of using CRISPR gene editing on embryos

The Independent  

For free real time breaking news alerts sent straight to your inbox sign up to our breaking news emails Sign up to our free breaking news emails Sign up to our free breaking news emails SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy A lab experiment aimed at …

Lab tests show risks of using CRISPR gene editing on embryos
4 years, 4 months ago

Lab tests show risks of using CRISPR gene editing on embryos

Associated Press  

A lab experiment aimed at fixing defective DNA in human embryos shows what can go wrong with this type of gene editing and why leading scientists say it’s too unsafe to try. “If our results had been known two years ago, I doubt that anyone would have gone ahead” and tried it on embryos intended for pregnancy, said biologist Dieter …

Too Soon to Give Green Signal to Techniques of Genome Editing for Human Embryo, Say Scientists
4 years, 6 months ago

Too Soon to Give Green Signal to Techniques of Genome Editing for Human Embryo, Say Scientists

News 18  

Techniques to genetically-edit human embryos should not be used until they are proved to be reliable and safe, an international commission said Thursday, in the wake of a scandal over gene-modified babies in China two years ago. Experts from the commission of the US National Academy of Medicine, US National Academy of Sciences, and Britain’s Royal Society said heritable genome …

Still too soon to try altering human embryo DNA, panel says
4 years, 6 months ago

Still too soon to try altering human embryo DNA, panel says

Associated Press  

It’s still too soon to try to make genetically edited babies because the science isn’t advanced enough to ensure safety, says an international panel of experts who also mapped a pathway for any countries that want to consider it. If drugs or gene therapy after birth can treat a disease, “then it doesn’t make sense to me to layer the …

It’s still too soon to try altering the DNA of human embryos, scientific panel says
4 years, 6 months ago

It’s still too soon to try altering the DNA of human embryos, scientific panel says

LA Times  

It’s still too soon to try to genetically edited human embryos because the science isn’t advanced enough to ensure safety, according to a report by an international panel of experts who also mapped a pathway for any countries that want to consider it. Thursday’s report comes nearly two years after a Chinese scientist shocked the world by revealing he’d helped …

Chinese researcher He Jiankui, who genetically edited babies, jailed for 3 years
5 years, 2 months ago

Chinese researcher He Jiankui, who genetically edited babies, jailed for 3 years

India TV News  

Chinese researcher He Jiankui, who shocked the world by announcing the birth of first genetically edited babies, was jailed on Monday for three years along with two others with lesser sentence for illegal medical practice by a court in southern China. He, who was also fined USD 430,000, claimed in November 2018 that the world's first genetically edited babies were …

World's first genetically altered babies born in China, scientist claims
5 years, 2 months ago

World's first genetically altered babies born in China, scientist claims

The Independent  

For free real time breaking news alerts sent straight to your inbox sign up to our breaking news emails Sign up to our free breaking news emails Sign up to our free breaking news emails SIGN UP I would like to be emailed about offers, events and updates from The Independent. “Gene editing itself is experimental and is still associated …

Chinese scientist who created genetically-edited babies gets fined, 3 years in prison
5 years, 2 months ago

Chinese scientist who created genetically-edited babies gets fined, 3 years in prison

Firstpost  

His work had resulted in a third genetically edited baby, who had been undisclosed till earlier this week, by Chinese media. A court in China on Monday sentenced He Jiankui, the researcher who shocked the global scientific community when he claimed that he had created the world’s first genetically edited babies, to three years in prison for carrying out “illegal …

Scientist who edited babies’ genes sentenced to prison
5 years, 2 months ago

Scientist who edited babies’ genes sentenced to prison

Live Mint  

The Chinese scientist who created the world’s first genetically altered babies has been sentenced to three years in prison and a lifelong ban from working in reproductive technology, state media reported on Monday. He Jiankui, a Shenzhen researcher who drew widespread condemnation when he revealed his experiment last year, will also have to pay a 3 million yuan fine, said …

Chinese court sentences 'gene-editing' scientist to three years in prison
5 years, 2 months ago

Chinese court sentences 'gene-editing' scientist to three years in prison

The Hindu  

A Chinese court sentenced the scientist who created the world's first “gene-edited” babies to three years in prison on December 30, according to the official Xinhua media. The editing process, which he calls gene surgery, “worked safely as intended” and the girls are “as healthy as any other babies”, he said in one video. He did not provide any written …

Never-seen-before extracts from 'outrageous' research of disgraced scientist He Jiankui
5 years, 3 months ago

Never-seen-before extracts from 'outrageous' research of disgraced scientist He Jiankui

Daily Mail  

He Jiankui, the disgraced scientist who was internationally condemned for gene-editing twin girls, may have put the health of the children at risk by adding unintended mutations into their genetic code. Dr Vassena adds: 'The idea that editing-derived embryos may one day be able to 'control the HIV epidemic,' as the authors claim, is preposterous. 'It's almost like not editing …

CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows
5 years, 6 months ago

CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows

NPR  

CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows Enlarge this image MOLEKUUL/SCIENCE PHOTO LIBRARY/Getty Images/Science Photo Libra MOLEKUUL/SCIENCE PHOTO LIBRARY/Getty Images/Science Photo Libra There's been a lot of excitement lately that the powerful gene-editing technique CRISPR could offer a new way to treat health problems ranging from cancer to blindness. Chinese scientists have published …

Scientists Attempt Controversial Experiment To Edit DNA In Human Sperm Using CRISPR
5 years, 7 months ago

Scientists Attempt Controversial Experiment To Edit DNA In Human Sperm Using CRISPR

NPR  

Scientists Attempt Controversial Experiment To Edit DNA In Human Sperm Using CRISPR Enlarge this image toggle caption Elias Williams for NPR Elias Williams for NPR First it was human embryos. "It doesn't matter whether you're manipulating the embryo or you're manipulating the sperm," says Françoise Baylis, a bioethicist at Dalhousie University in Canada, who is advising the World Health Organization …

The World Health Organization Says No More Gene-Edited Babies
55 years, 2 months ago

The World Health Organization Says No More Gene-Edited Babies

Wired  

The world’s largest public health authority has weighed in with the most authoritative statement yet on the use of Crispr to alter the DNA of human babies. Eight months after a rogue Chinese scientist revealed he had secretly created the world’s first gene-edited children, the World Health Organization is asking countries to put a stop to any experiments that would …

HIV cure using gene editing shows promise in animal testing
5 years, 8 months ago

HIV cure using gene editing shows promise in animal testing

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Clinical trials for the gene-editing component of the cure could start as early as next …

A Russian Biologist Wants To Create More Gene-Edited Babies
5 years, 9 months ago

A Russian Biologist Wants To Create More Gene-Edited Babies

NPR  

A Russian Biologist Wants To Create More Gene-Edited Babies Enlarge this image toggle caption Gregor Fischer/picture alliance via Getty Images Gregor Fischer/picture alliance via Getty Images A Russian scientist says he wants to create more genetically modified babies, flouting international objections that such a step would be premature, unethical and irresponsible. We demonstrated it's safe to use," says Rebrikov, who …

Controversial gene-edited Chinese twins at greater risk of death in later life
5 years, 9 months ago

Controversial gene-edited Chinese twins at greater risk of death in later life

Daily Mail  

The genetic mutation introduced into two babies by a Chinese scientist in 2018 may be associated with a 21 per cent higher chance of early death in later life. As the CCR5 gene codes for a protein involved in many body functions, researchers say that there could be many different possible reasons for the risk of early death. Scroll down …

2 Chinese Babies With Edited Genes May Face Higher Risk Of Premature Death
5 years, 9 months ago

2 Chinese Babies With Edited Genes May Face Higher Risk Of Premature Death

NPR  

2 Chinese Babies With Edited Genes May Face Higher Risk Of Premature Death Enlarge this image toggle caption Anthony Kwan/Bloomberg/Getty Images Anthony Kwan/Bloomberg/Getty Images There are new concerns about the world's first genetically modified babies. "I think we should always be concerned about unanticipated consequences of any new technology, not just gene-editing and embryos," says George Church, a professor of …

Why is China laying down gene editing rules?
5 years, 9 months ago

Why is China laying down gene editing rules?

The Hindu  

The story so far: In a bid to make babies immune to infection by the human immunodeficiency virus, He Jiankui, a researcher from the Southern University of Science and Technology in Shenzhen, China, used a clinically untested gene editing tool to modify a particular gene. The CRISPR-Cas9 gene editing tool thus has two components — a short RNA sequence that …

Scientists asked disgraced Chinese scientist He Jiankui for help gene-editing human embryos
5 years, 9 months ago

Scientists asked disgraced Chinese scientist He Jiankui for help gene-editing human embryos

Daily Mail  

A fertility clinic in Dubai asked disgraced scientist He Jiankui for help in controversial experiments modifying the genes of human embryos. Jennifer Doudna, a University of California, Berkeley, co-inventor of the CRISPR gene-editing tool that He Jiankui used, said that she has heard of others who want to edit embryos William Hurlbut of Stanford University speaks to reporters during the …

China draws up tighter rules on human gene and embryo trials
5 years, 11 months ago

China draws up tighter rules on human gene and embryo trials

The Hindu  

China’s top legislature will consider tougher rules on research involving human genes and embryos, the first such move since a Chinese scientist sparked controversy last year by announcing he had made the world’s first “gene-edited” babies. Under the draft laws sent to China’s legislature for review on Saturday, medical and human trials would face closer scrutiny and stricter requirements, such …

Chinese scientists defend implanting human gene into monkeys’ brains
5 years, 11 months ago

Chinese scientists defend implanting human gene into monkeys’ brains

CNN  

Hong Kong CNN — A Chinese researcher who sparked improved cognitive function in monkeys by implanting human genes into their brains has defended his experiment, which has divided the scientific community. In Su’s 2019 study, 11 rhesus monkeys were successfully implanted with copies of the human MCPH1 gene, an important marker for “brain development and brain evolution.” Analysis of the …

Another scientist is editing genes in human embryos, but ethically this time
6 years, 1 month ago

Another scientist is editing genes in human embryos, but ethically this time

Firstpost  

So far, the Columbia University scientist has allowed modified embryos to live no longer than one day. While the Columbia University scientist, Dr Dieter Egli, isn’t creating any genetically-modified babies or implanting these gene-edited embryos into mothers, he admits that the ultimate goal of his future research is probably just that. Egli is a developmental biologist currently working on genetically-modified …

US Nobel laureate aware of gene-edited baby kept the news from authorities, public
6 years, 1 month ago

US Nobel laureate aware of gene-edited baby kept the news from authorities, public

Firstpost  

The Nobel-winner remained an adviser to Jiankui’s company for 8 months after he knew of the study. Emails obtained by The Associated Press under a public records request show that Nobel Prize winner Craig Mello of the University of Massachusetts learned about the pregnancy last April from He in a message titled “Success!” “I’m glad for you, but I’d rather …

China's second gene-edited foetus could now be 12 to 14 weeks old: US physician
6 years, 2 months ago

China's second gene-edited foetus could now be 12 to 14 weeks old: US physician

Firstpost  

Chinese scientist He Jiankui had revealed that he had successfully altered the DNA of twin girls. The second woman carrying a gene-edited foetus in China could now be 12 to 14 weeks into her pregnancy, according to a US physician in close contact with the researcher who claimed to have created the world’s first genetically-modified babies last year. William Hurlbut, …

Chinese scientist behind gene-edited baby study gets fired for illegal actions
6 years, 2 months ago

Chinese scientist behind gene-edited baby study gets fired for illegal actions

Firstpost  

Experts expressed their hope that the report was just the beginning, & more action would be taken. A Chinese scientist who created what he said were the world’s first “gene-edited” babies evaded oversight and broke ethical boundaries in a quest for fame and fortune, state media said on Monday, as his former university said he had been fired. He had …

Gene-edited babies were illegal, say Chinese authorities
6 years, 2 months ago

Gene-edited babies were illegal, say Chinese authorities

CNN  

CNN — Authorities in China say experiments which led to the birth of the world’s first gene-edited babies broke the country’s laws, state-run Xinhua news reported Monday. On Monday, investigators from Guangdong Province Health Commission said that “the case has been initially identified as an explicitly state-banned human embryo-editing activity for reproductive purposes conducted by He Jiankui,” Xinhua reported. The …

Gene-edited babies: Chinese scientist was told ‘not to proceed’
6 years, 2 months ago

Gene-edited babies: Chinese scientist was told ‘not to proceed’

CNN  

CNN — As 2018 drew to a close, one scientist unveiled research that entered a new era of science. Everyone he talked to – which was not many people – had said “don’t go there,” “don’t do it,” explained Robin Lovell-Badge of the UK research facility the Francis Crick Institute, who organized the scientific summit in Hong Kong during which …

Scientists in China are losing touch with patients of gene editing trials: Report
6 years, 2 months ago

Scientists in China are losing touch with patients of gene editing trials: Report

Firstpost  

China has asked hospitals, universities to submit reports on all gene-editing trials since 2013. The technology that powered this boost, a tool called CRISPR-Cas 9 to edit DNA inside living cells, has come under fire from a recent controversy from one such researcher, He Jiankui, whose study led to the birth of twin girls “Lulu and Nana”, who Jiankui claims …

Chinese scientists who edited human genes have lost touch with the patients whose DNA they tweaked
6 years, 2 months ago

Chinese scientists who edited human genes have lost touch with the patients whose DNA they tweaked

Daily Mail  

Chinese scientists who edited human genes have lost touch with the patients they treated, according to a new Wall Street Journal report. The scientific community is concerned about ethics and unintended consequences just weeks after another Chinese scientist claimed he modified the DNA of twin girls to make them resistant to AIDS - and that he is working on another …

Experts urge oversight of experiments
6 years, 3 months ago

Experts urge oversight of experiments

China Daily  

Genetics research, conceptual artwork. CHINA DAILY Scientists, researchers say gene editing project was unnecessary, irresponsible The world urgently needs better international oversight of genome editing in human embryos, and to clarify the boundaries for related research, according to an editorial published in the journal Science on Friday. "To maintain the public's trust that someday genome editing will be able to …

Experts urge oversight of experiments
6 years, 3 months ago

Experts urge oversight of experiments

China Daily  

Genetics research, conceptual artwork. CHINA DAILY Scientists, researchers say gene editing project was unnecessary, irresponsible The world urgently needs better international oversight of genome editing in human embryos, and to clarify the boundaries for related research, according to an editorial published in the journal Science on Friday. "To maintain the public's trust that someday genome editing will be able to …

Even China Roundly Condemns Editing the Genes of Babies
6 years, 3 months ago

Even China Roundly Condemns Editing the Genes of Babies

Wired  

The birth of Lulu and Nana—the first two babies believed to be born with Crispr-edited DNA—has triggered soul-searching in China as tech innovators, scientific researchers, and government bureaucrats reconcile conflicting values. On Weibo, a popular Chinese platform, 1.9 billion people viewed the hashtag “First Case of Gene-Edited HIV Immune Babies.” He’s research seemed to fit the script of the “China …

Chinese gene-editing scientist is missing amid rumours of arrest
6 years, 3 months ago

Chinese gene-editing scientist is missing amid rumours of arrest

Daily Mail  

The whereabouts of Chinese scientist He Jiankui, who claims to have created the world's first gene-edited babies, remain unknown amid rumours that he has been arrested. Reports claimed He was placed under effective house arrest in Shenzhen after making an appearance at the Second International Summit on Human Genome Editing in Hong Kong last Wednesday. His whereabouts remain unknown after …

Could anyone have stopped gene-edited babies experiment?
6 years, 3 months ago

Could anyone have stopped gene-edited babies experiment?

Associated Press  

HONG KONG — Early last year, a little-known Chinese researcher turned up at an elite meeting in Berkeley, California, where scientists and ethicists were discussing a technology that had shaken the field to its core — an emerging tool for “editing” genes, the strings of DNA that form the blueprint of life. U.S. National Institutes of Health Director Francis Collins …

Gene editing experts discuss whether controversy is rushing the still-young technology
6 years, 3 months ago

Gene editing experts discuss whether controversy is rushing the still-young technology

Firstpost  

A Chinese scientist’s stunning claim he has pioneered the world’s first genetically modified baby has suddenly made the eternal debate over ethics and emerging scientific capabilities pressing and real. “It’s obvious that everything that is technically feasible is not ethically desirable,” said Cynthia Fleury, a member of the French Ethics Committee. “Trying to rush the technology” The concern of the …

What are the ethics of baby gene-editing?
6 years, 3 months ago

What are the ethics of baby gene-editing?

India Today  

Paris, Dec 1 A Chinese scientist's stunning claim he has pioneered the world's first genetically modified baby has suddenly made the eternal debate over ethics and emerging scientific capabilities pressing and real. "It's obvious that everything that is technically feasible is not ethically desirable," said Cynthia Fleury, a member of the French Ethics Committee. "Trying to rush the technology forwards, …

‘Extremely abominable’: Chinese gene-editing scientist faces law
6 years, 3 months ago

‘Extremely abominable’: Chinese gene-editing scientist faces law

Al Jazeera  

China condemns the work of He Jiankui as institutions distance themselves from the academic who gene-edited twin girls. Xi said genetically engineering the DNA of twin girls so they would not develop HIV, breached scientific ethics, adding that gene-editing of human embryos for reproduction purposes was “explicitly banned” in China. China’s National Health Commission said He’s activities would be investigated …

The scientist, the twins and the experiment that geneticists say went too far
6 years, 3 months ago

The scientist, the twins and the experiment that geneticists say went too far

CNN  

Hong Kong CNN — Humanity was reluctantly dragged into a new era this week. “I see it as one of those moments that happens once every few decades,” said William Hurlbut, Senior Research Scholar at Stanford University Medical Center’s Department of Neurobiology. When one audience member at the summit asked whether He had thought about how the girls would see …

CRISPR: The genetic editing tool that holds promise & peril
6 years, 3 months ago

CRISPR: The genetic editing tool that holds promise & peril

Live Mint  

Chinese researcher He Jiankui has claimed that he used CRISPR to produce the world’s first “designer babies”. Jiankui said he used CRISPR—Clustered Regularly Interspaced Short Palindromic Repeats—to alter the genes of a pair of twins while they were embryos to make the babies resistant to HIV, the virus that causes AIDS. In 2017, a US science and medicine advisory group …

Science conference slams 'deeply disturbing' baby gene-editing claim
6 years, 3 months ago

Science conference slams 'deeply disturbing' baby gene-editing claim

India Today  

Hong Kong, Nov 29 A scientist who upended a Hong Kong conference with his claim to have created the world's first genetically-edited babies cancelled a fresh talk and was heavily criticised by organisers Thursday, who labelled him as irresponsible. He Jiankui had told a packed biomedical conference Wednesday he was "proud" to have successfully altered the DNA of twin girls …

China suspends He Jiankui’s research activities
6 years, 3 months ago

China suspends He Jiankui’s research activities

CNN  

Hong Kong CNN — China has suspended the research activities of the scientists who claimed to have created the world’s first gene-edited babies, state-run Xinhua news reported Thursday. “The gene-edited twins matter reported by the media has brazenly violated Chinese laws and regulations and breached the science ethics bottom line, which is both shocking and unacceptable,” said Xu Nanping, vice …

Discover Related