Origins of virus responsible for Covid-19 traced to horseshoe bats
2 years, 10 months ago

Origins of virus responsible for Covid-19 traced to horseshoe bats

The Independent  

Get the free Morning Headlines email for news from our reporters across the world Sign up to our free Morning Headlines email Sign up to our free Morning Headlines email SIGN UP I would like to be emailed about offers, events and updates from The Independent. It is clear that recombination is a defining feature of SARS-related coronaviruses and essential to account for when examining the viruses’ evolution Spyros Lytras SARS-related coronaviruses, which include SARS-CoV-2, are dispersed over a large geographical area across China and South East Asia. Professor David L Robertson, senior author on the study, said: “Our analysis highlights the need for dramatically more wildlife sampling to pinpoint the exact origins of SARS-CoV-2 and understand more fully the risk of infection of humans by viruses like these across China and South East Asia. “The finding of bat coronaviruses that can so readily use the human – and other mammals’ – ACE2 receptor without having to undergo any significant evolutionary change underscores the inevitability of future spillovers.” The new research analysed a wide distribution of related viruses in bats, with shared markers of viral recombination suggesting that SARS-CoV-2 ancestors were frequently transmitting amongst bats species, with the virus changing and recombining over time as host bats were infected with two coronaviruses at once. “It is clear that recombination is a defining feature of SARS-related coronaviruses and essential to account for when examining the viruses’ evolution.” Scientists said that more research is needed to pinpoint the exact origins of SARS-CoV-2’s progenitor to help prepare for the future.

History of this topic

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