Study explains how the immune system reacts differently to Alzheimer's inflammation than regular infections

Brain inflammation, while an important aspect of the immune response, plays a negative effect on Alzheimer's disease. {{^userSubscribed}} {{^usCountry}} {{/usCountry}} {{#usCountry}} {{/usCountry}} {{/userSubscribed}} {{^userSubscribed}} {{^usCountry}} {{/usCountry}} {{#usCountry}} {{/usCountry}} {{/userSubscribed}} New research reveals key differences in how the brain's immune system responds to the disease compared to a bacterial infection. {{^usCountry}} {{/usCountry}} How immune system responds The study focuses on how immune cells react to amyloid-beta plaques, a hallmark of Alzheimer's, and how this immune response differs from the reaction to bacterial toxins. {{^userSubscribed}} {{^usCountry}} {{/usCountry}} {{#usCountry}} {{/usCountry}} {{/userSubscribed}} {{^userSubscribed}} {{^usCountry}} {{/usCountry}} {{#usCountry}} {{/usCountry}} {{/userSubscribed}} "Our findings reveal a crucial distinction in how the brain's immune system reacts to a bacterial infection versus Ab clumps," said Dey. "The slower, more sustained immune activation by large Ab aggregates may contribute to the chronic inflammation seen in Alzheimer's disease."