India working on developing cheap treatment for blood cancer in children
1 week, 3 days ago

India working on developing cheap treatment for blood cancer in children

India Today  

India is taking a major step towards making CAR-T cell therapy, a cutting-edge cancer treatment for certain types of blood cancers, affordable and accessible to its citizens. Under the central government’s National Biopharma Mission, supported by the Biotechnology Industry Research Assistance Council, researchers at Tata Memorial Centre, Mumbai, have started the country's first clinical trial for this advanced therapy in pediatric population. INDIA'S FIRST CLINICAL TRIAL FOR AFFORDABLE CAR-T CELL THERAPY The trial focusses on treating children with a type of blood cancer called relapsed/refractory B-cell Acute Lymphoblastic Leukemia, which does not respond to standard treatments. "BIRAC's support through NBM has been instrumental in bringing indigenously developed CAR-T therapy to India for children, significantly reducing costs, advancing clinical research, and improving patient outcomes," said Dr Raj K Shirumalla, Mission Director of National Biopharma Mission, in an exclusive interview with India Today Digital.

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History of this topic

Crafted in Indian labs, NexCAR19 takes India to next level in cancer care
8 months, 1 week ago

Crafted in Indian labs, NexCAR19 takes India to next level in cancer care

The Hindu  

Alka Dwivedi, is striving to develop patient-focused therapy for cancer. This leads her to join Rahul Purwar, a Professor at the Indian Institute of Technology Bombay, who is working on developing affordable CAR-T cell therapy in India. Clinical trials After successfully developing CAR-T cell therapy, the team had to approach the Central Drugs Standard Control Organization for clinical trial approval. …

President to inaugurate indigenous cancer therapy at IIT Bombay
8 months, 2 weeks ago

President to inaugurate indigenous cancer therapy at IIT Bombay

Hindustan Times  

Mumbai: President Droupadi Murmu is set to inaugurate India’s pioneering CAR T-Cell therapy for advanced blood cancer treatment at the Indian Institute of Technology Bombay, Powai campus on April 4. President Droupadi Murmu CAR T-Cell therapy, a live drug, is a personalised treatment. Led by Dr. Gaurav Narula, a paediatric hematologist-oncologist at Tata Hospital, and Dr. Rahul Purwar, a faculty …

Two doctors, a battle, and a victory against cancer: Behind India’s low-cost CAR T-cell therapy
9 months, 3 weeks ago

Two doctors, a battle, and a victory against cancer: Behind India’s low-cost CAR T-cell therapy

Hindustan Times  

It began with a simple Google search. “I stumbled upon Purwar’s CAR T-cell PowerPoint while preparing for my own research paper on the subject and wrote to him,” says Dr Narula. “Keeping in mind ongoing research, trials and clinical evidence abroad, my idea was to have a CAR T-cell therapy that would cause long-term cancer remission,” says Dr Narula. Dr …

German firm Miltenyi Biotec opens office, plans Cell and Gene Therapy CoE
9 months, 3 weeks ago

German firm Miltenyi Biotec opens office, plans Cell and Gene Therapy CoE

The Hindu  

German firm Miltenyi Biotec on Tuesday announced the launch of operations in India with the opening of an office in Hyderabad and further plans to invest in a first-of-its-kind Cell and Gene Therapy centre of excellence for Indian academia and industry. Scientists, researchers, industry experts and clinicians can get classroom to hands-on training on cell and gene therapy approaches, from …

Explained | Why CAR T-cell therapy is cancer treatment’s next moonshot
1 year, 10 months ago

Explained | Why CAR T-cell therapy is cancer treatment’s next moonshot

The Hindu  

February 08, 2023 01:30 pm | Updated 02:02 pm IST The story so far: The three major forms of treatment for any cancer are surgery, radiotherapy, and systemic therapy. Unlike chemotherapy or immunotherapy, which require mass-produced injectable or oral medication, CAR T-cell therapies use a patient’s own cells. In CAR T-cell therapy, the patient’s blood is drawn to harvest T-cells …

Providing affordable cancer treatment in India paramount: Physician
1 year, 11 months ago

Providing affordable cancer treatment in India paramount: Physician

The Hindu  

Renowned cancer physician and author Siddhartha Mukherjee on Tuesday said one of the very important goals for him and his team is to make Chimeric Antigen Receptor T-cell therapy affordable in India. Mr. Mukherjee, who is a cancer physician at Columbia University, along with Biocon chairperson Kiran Mazumdar-Shaw and 5AM Ventures managing partner Kush Paramar, has co-funded Bengaluru-based start-up Immuneel …

Cell treatment that 'resets' immune system gives 250,000 British blood cancer patients new hope
1 year, 11 months ago

Cell treatment that 'resets' immune system gives 250,000 British blood cancer patients new hope

Daily Mail  

Patients with common yet hard-to-treat blood cancer could benefit from treatment that reprogrammes the immune system to fight the disease. TRIAL SUCCESS: Robin Edwards, 66, with his two grandchildren 'I can't say I'm cured, but there's no sign of cancer at the moment,' said Mr Edwards after his successful CAR-T-cell therapy Blood cancers affect cells in the blood and include …

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