Science for all newsletter
3 weeks, 5 days ago

Science for all newsletter

The Hindu  

Scientists may have unlocked a new milestone in cancer treatment. An individual who received CAR T-cell therapy has been in remission for 18 years without requiring any other treatments, researchers reported in Nature Medicine on February 17. CAR T-cell therapy uses genetically altered immune cells to target cancer cells and destroy them. CAR T-cell therapy works by ‘upgrading’ these T cells to not miss any cancer cells. The authors of the newly published study have expressed belief that 18 years may be the longest yet an individual has been cancer-free after receiving CAR T-cell therapy.

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Indian biotech firm pioneers CAR-T cell therapy for cancer treatment
1 week, 5 days ago

Indian biotech firm pioneers CAR-T cell therapy for cancer treatment

India Today  

Delhi-based startup Cellogen Therapeutics has secured regulatory approval for the patent of the world's first indigenously developed Bi-Specific 3rd Generation Chimeric Antigen Receptor T cells. CAR-T cell therapy has been largely dominated by Western countries, with treatment costs exceeding $400,000 per patient. Dr. Tanveer Ahmad, lead researcher and expert in CAR-T cell therapy, highlighted the innovation’s significance: "Our Bi-Specific 3rd …

India's first homegrown CAR-T cell therapy shows 73% success rate against cancer
Trending News
2 weeks ago

India's first homegrown CAR-T cell therapy shows 73% success rate against cancer

India Today  

After over a year of approval by India's drug regulator, researchers from the Indian Institute of Technology Bombay and the Tata Memorial Hospital, Mumbai, have published the clinical trial data of NexCAR19 - India's first indigenous Car-T cell therapy. CAR-T cell therapy is a type of immunotherapy for cancer treatment in which the patient's immune cells or T cells are …

Study of CAR T-Cell therapy trial in India, in leukaemia patients, shows 73% response rate
2 weeks ago

Study of CAR T-Cell therapy trial in India, in leukaemia patients, shows 73% response rate

The Hindu  

A study published in The Lancet Haematology has reported a 73% response rate for CAR T-cell therapy among patients with certain blood cancers. These cells help to prevent a relapse,” said Hasmukh Jain, professor of medical oncology at Tata Memorial Hospital Addressing treatment gaps In cases where B-cell tumours return after remission or do not respond to initial treatment, treatment …

India’s blood cancer gene therapy shows 73% response rate in clinical trials: Report
2 weeks ago

India’s blood cancer gene therapy shows 73% response rate in clinical trials: Report

Hindustan Times  

An indigenously developed gene therapy for specific blood cancers has shown a 73 per cent response rate among patients in India, according to results of clinical trials published in The Lancet Haematology journal. 'CAR T-cell therapy', the treatment involves modifying genes in one's T-cells -- a type of immune cells -- to help fight cancer. Known as 'CAR T-cell therapy', …

Engineering medicine: The future of CAR-T and CRISPR technologies
1 month, 1 week ago

Engineering medicine: The future of CAR-T and CRISPR technologies

The Hindu  

The fourth industrial revolution marked by the fusion of technologies is blurring the lines between the physical, digital and biological worlds. On December 8, 2023, the United States’ Food and Drug Administration approved of a gene therapy treatment for transfusion dependent beta-thalassemia and sickle cell anaemia patients — a decision that will revolutionise medicine and change countless lives. CAR-T Cell …

India working on developing cheap treatment for blood cancer in children
3 months, 2 weeks ago

India working on developing cheap treatment for blood cancer in children

India Today  

India is taking a major step towards making CAR-T cell therapy, a cutting-edge cancer treatment for certain types of blood cancers, affordable and accessible to its citizens. Under the central government’s National Biopharma Mission, supported by the Biotechnology Industry Research Assistance Council, researchers at Tata Memorial Centre, Mumbai, have started the country's first clinical trial for this advanced therapy in …

Radical CAR-T cancer therapy’s risk of causing cancer is small
8 months, 4 weeks ago

Radical CAR-T cancer therapy’s risk of causing cancer is small

The Hindu  

In the last few decades, scientists have finally learned to harness the immune system to successfully treat cancer. Car-T therapy, short for “chimeric antigen receptor T-cell”, is a cutting-edge treatment that reprogrammes a patient’s immune cells to fight their cancer. Initially, the FDA mentioned that it had observed 20 cases where patients developed new immune-cell cancers, such as lymphomas or …

Two doctors, a battle, and a victory against cancer: Behind India’s low-cost CAR T-cell therapy
1 year ago

Two doctors, a battle, and a victory against cancer: Behind India’s low-cost CAR T-cell therapy

Hindustan Times  

It began with a simple Google search. “I stumbled upon Purwar’s CAR T-cell PowerPoint while preparing for my own research paper on the subject and wrote to him,” says Dr Narula. “Keeping in mind ongoing research, trials and clinical evidence abroad, my idea was to have a CAR T-cell therapy that would cause long-term cancer remission,” says Dr Narula. Dr …

Novel treatment shows promise against rare cancer in kids
1 year, 11 months ago

Novel treatment shows promise against rare cancer in kids

Associated Press  

A novel treatment using supercharged immune cells appears to work against tumors in children with a rare kind of cancer, researchers reported Wednesday. “Those kids were all destined to die without that therapy,” said University of Pennsylvania’s Dr. Carl June, a pioneer of CAR-T therapy who was not involved in the new research. Many of the children had a side …

Novel treatment shows promise against rare cancer in kids
1 year, 11 months ago

Novel treatment shows promise against rare cancer in kids

LA Times  

A typical neuroblastoma tumor is seen under a microscope. In a new study, a novel treatment called CAR-T cell therapy appeared to work against tumors in children with the rare kind of cancer. A novel treatment using supercharged immune cells appears to work against tumors in children with a rare kind of cancer, researchers reported Wednesday. “Those kids were all …

Explained | Why CAR T-cell therapy is cancer treatment’s next moonshot
2 years, 1 month ago

Explained | Why CAR T-cell therapy is cancer treatment’s next moonshot

The Hindu  

February 08, 2023 01:30 pm | Updated 02:02 pm IST The story so far: The three major forms of treatment for any cancer are surgery, radiotherapy, and systemic therapy. Unlike chemotherapy or immunotherapy, which require mass-produced injectable or oral medication, CAR T-cell therapies use a patient’s own cells. In CAR T-cell therapy, the patient’s blood is drawn to harvest T-cells …

Cell treatment that 'resets' immune system gives 250,000 British blood cancer patients new hope
2 years, 3 months ago

Cell treatment that 'resets' immune system gives 250,000 British blood cancer patients new hope

Daily Mail  

Patients with common yet hard-to-treat blood cancer could benefit from treatment that reprogrammes the immune system to fight the disease. TRIAL SUCCESS: Robin Edwards, 66, with his two grandchildren 'I can't say I'm cured, but there's no sign of cancer at the moment,' said Mr Edwards after his successful CAR-T-cell therapy Blood cancers affect cells in the blood and include …

CAR-T revolution: Radical new cancer cure offers better efficiency, one-and-done solution
5 years, 5 months ago

CAR-T revolution: Radical new cancer cure offers better efficiency, one-and-done solution

Firstpost  

An unexpected early morning phone call from the hospital is never good news. Birzer’s cancer had grown, and fast — first during one type of chemotherapy, then through a second. What if we could genetically engineer a patient’s own immune cells to spot and fight cancer, as a sort of “best hits” of genetic therapy and immunotherapy? One of Birzer’s …

WHAT IS CAR-T CELL THERAPY?
6 years, 2 months ago

WHAT IS CAR-T CELL THERAPY?

Daily Mail  

CAR-T cell therapies are available on the NHS for children and people up to 25 with B cell acute lymphoblastic leukaemia. The treatments involve taking a specific immune cell - known as T cells - from a patient's blood. NICE - which provides guidance for the NHS - also recommends CAR-T therapy for adults with diffuse large B-cell lymphoma and …

US approves breakthrough leukaemia treatment that 'weaponises' blood cells to attack cancer
7 years, 7 months ago

US approves breakthrough leukaemia treatment that 'weaponises' blood cells to attack cancer

The Independent  

Sign up to our free Living Well email for advice on living a happier, healthier and longer life Live your life healthier and happier with our free weekly Living Well newsletter Live your life healthier and happier with our free weekly Living Well newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. …

Leukaemia breakthrough CAR-T uses children's own blood cells to attack cancer
7 years, 7 months ago

Leukaemia breakthrough CAR-T uses children's own blood cells to attack cancer

ABC  

A breakthrough treatment that genetically engineers patients' own blood cells into an army of assassins to destroy childhood leukemia has been approved by US officials, opening a new era in cancer care. Key points: One-off treatments are made specifically for each patient and cost $600,000 Scientists are trying to make similar therapies for more common tumours such as brain, breast …

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