Antibody tests for Covid-19 wrong half the time, CDC says
CNNCNN — Antibody tests used to determine if people have been infected in the past with Covid-19 might be wrong up to half the time, the US Centers for Disease Control and Prevention said in new guidance posted on its website. “Serologic test results should not be used to make decisions about returning persons to the workplace.” Health officials or health care providers who are using antibody tests need to use the most accurate test they can find and might need to test people twice, the CDC said in the new guidance. “It cannot be assumed that individuals with truly positive antibody test results are protected from future infection,” the CDC says in the updated guidelines. “Serologic testing should not be used to determine immune status in individuals until the presence, durability, and duration of immunity is established.” The new CDC guidelines echo advice from groups such as the University of Minnesota, which cautions against using antibody tests to make policy decisions. “Alternatively, the same test in a population with an antibody prevalence exceeding 52% will yield a positive predictive greater than 95%, meaning that less than one in 20 people testing positive will have a false positive test result.” Get CNN Health's weekly newsletter Sign up here to get The Results Are In with Dr. Sanjay Gupta every Tuesday from the CNN Health team.