Scientifically Speaking | The emergence of Omicron was expected
Hindustan TimesResearchers have been saying for months that as long as one part of the world remains unprotected from SARS-CoV-2 infection, there is an opportunity for new variants to emerge. Omicron is a new variant of concern first identified in Botswana and reported to the World Health Organization by South Africa last week. But variants can also emerge over time as a result of rapid spread through many people instead of in one person.” There have been multiple, well-documented cases of SARS-CoV-2 variants emerging in immunosuppressed patients. Gupta’s team tracked mutations in an immunosuppressed patient with persistent SARS-CoV-2 infection over 101 days and found that the number of mutations exploded after convalescent plasma therapy. A feature that these variants share with Delta and with Omicron is the large number of mutations that result in changes in the spike protein.