ICMR may remove plasma therapy from Covid-19 treatment guidelines
4 years, 2 months ago

ICMR may remove plasma therapy from Covid-19 treatment guidelines

Live Mint  

New Delhi: The government is planning to delete convalescent plasma therapy from the national guidelines for covid-19 treatment after the Indian Council of Medical Research’s clinical trial showed that the therapy did not significantly benefit patients suffering from the disease, ICMR DG Balram Bhargava said on Tuesday. ICMR, which is the government’s apex bio-medical research agency, had conducted a 464 patient multi-centre study, and in September results showed that the therapy did not really help beat covid-19. Bhargava also said that the task force is discussion whether remdesivir and hydroxychloroquine can be removed from the clinical management guidelines, or continue to be included, after a recently released pre-print of World Health Organization Solidarity Trial showed that four repurposed dugs —hydroxychorloquine, remdesivir, interferon-B and lopinavir — did not help in treating covid-19 patients either. Convalescent plasma therapy and hydroxychloroquine in particular have seen significant controversies in India during the pandemic, with private hospitals accused of charging steep fees for the plasma therapy and multiple trials showing that hydroxychloroquine posed a risk for patients with cardiac conditions while not providing much benefit.

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History of this topic

Studies show XBB.1.16 is not clinically more severe
1 year, 8 months ago

Studies show XBB.1.16 is not clinically more severe

Hindustan Times  

The XBB.1.16 sub-variant of the Omicron strain of the SARS-CoV-2 virus that causes Covid does not exhibit higher clinical severity according to preliminary results from laboratory studies being conducted in the country to know disease characteristics, according to people familiar with the matter. According to the World Health Organisation, mutations at position 478 of the SARS-CoV-2 spike protein have been …

FDA revokes authorization for key anti-COVID drug, a blow for vulnerable Americans
1 year, 10 months ago

FDA revokes authorization for key anti-COVID drug, a blow for vulnerable Americans

LA Times  

A two-shot dose of Evusheld at a University of Washington Medicine clinic in Seattle. For her patients, she said, “it was kind of like being told the seat belts in your car won’t work anymore, and we’re not going to be able to replace them with anything.” In recent months, nine new subvariants of the dominant Omicron strain have proven …

‘Erroneous’: Centre dismisses Covid vaccine's ‘multiple side effects’ report
1 year, 11 months ago

‘Erroneous’: Centre dismisses Covid vaccine's ‘multiple side effects’ report

Hindustan Times  

Union ministry of health and family welfare on Tuesday dismissed media reports regarding the Indian Council of Medical Research and Central Drugs Standard Control Organisation admitting to ‘multiple side-effects Covid-19 vaccines'. Terming the report “erroneous”, the ministry said that ICMR has only provided a list of benefits and drawbacks of the Covid-19 vaccine. Read| Centre unlikely to procure more Covid …

Expert Bodies like ICMR Best Judges, Says Delhi High Court on Plea to Allow Homoeopathy for Mild Covid
2 years, 1 month ago

Expert Bodies like ICMR Best Judges, Says Delhi High Court on Plea to Allow Homoeopathy for Mild Covid

News 18  

The Delhi High Court on Tuesday observed that expert statutory bodies like the Indian Council for Medical Research are the “best judges” to decide and approve “medical protocols” in treating mild Covid-19 cases. The court was hearing a Public Interest Litigation filed by two doctors in 2020 seeking directions to the ministry of AYUSH for allowing homoeopathic medicines Arsenicum album …

New COVID-19 treatment rules: India cuts down use of Remdesivir, Tocilizumab, multivitamins, steroids
2 years, 11 months ago

New COVID-19 treatment rules: India cuts down use of Remdesivir, Tocilizumab, multivitamins, steroids

Firstpost  

According to the new guidelines, Remdesivir may be considered only in patients who have completed 10 days since the start of the symptoms and require supplemental oxygen. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with COVID-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the …

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment
2 years, 11 months ago

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment

News 18  

India has cut down on the use of the experimental drug Remdesivir and immunosuppressive drug Tocilizumab for the treatment of Covid-19. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with Covid-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the overuse of steroids, the protocol for …

What you should know about treating Covid-19
3 years ago

What you should know about treating Covid-19

Live Mint  

Within a few weeks, the US could have access to the first antiviral pills to treat Covid-19, either from Pfizer Inc. or Merck & Co. and partner Ridgeback Biotherapeutics LP. Doctors say an initial step is to monitor symptoms to determine whether infected people could be considered at low or high risk for developing severe disease. Patients who don’t respond …

2 Indian Firms Seek Regulator Nod to Cease Trials of anti-Covid Pill Molnupiravir on 'Moderate' Patients
3 years, 2 months ago

2 Indian Firms Seek Regulator Nod to Cease Trials of anti-Covid Pill Molnupiravir on 'Moderate' Patients

News 18  

Two pharmaceutical companies have sought permission from India’s drug regulator to discontinue the phase III trials of American firm Merck & Co’s experimental antiviral drug molnupiravir in moderate Covid-19 patients, a government document shows, though one of the two manufacturers told News18.com that the “results have come out exceedingly well” in mild cases. Aurobindo Pharma and MSN Laboratories have presented …

Why HCQ and Ivermectin were removed from India's Covid-19 treatment protocol
3 years, 3 months ago

Why HCQ and Ivermectin were removed from India's Covid-19 treatment protocol

India Today  

The Indian Council of Medical Research and the National Task Force on Covid-19 have dropped the use of Ivermectin and Hydroxychloroquine drugs from their revised guidelines for the treatment of the infection. “HCQ may be considered for removal from guideline, with recommendation to use with caution only in clinical trial setting,” said the document titled ‘considerations for exclusion of Ivermectin …

Use of plasma therapy for Covid may cause adverse events: Study
3 years, 3 months ago

Use of plasma therapy for Covid may cause adverse events: Study

Hindustan Times  

Even with doubtful efficacy, antibody-rich plasma from recovered Covid-19 patients continued to be used for the treatment of those suffering from the infection during the second wave of the pandemic, with people queuing up at plasma banks and looking for donors online. But a recent Canadian study published in the journal Nature has shown that not only did plasma therapy …

Antibody cocktail treatment can help Covid patients recover faster, reduces mortality: BMC
3 years, 5 months ago

Antibody cocktail treatment can help Covid patients recover faster, reduces mortality: BMC

India Today  

The Brihanmumbai Municipal Corporation on Monday said that antibody cocktail treatment can help Covid-19 patients recover faster and reduces mortality rate. The civic body's claim is based on an experiment of antibody cocktail conducted by Mumbai's Seven Hills hospital on 200 patients. ANTIBODY COCKTAIL FOR COVID-19 TREATMENT In order to successfully treat the affected patients and to alleviate the strain …

ICMR to Conduct Clinical Trial for Evaluation of Covid Therapy with Oxford University
3 years, 5 months ago

ICMR to Conduct Clinical Trial for Evaluation of Covid Therapy with Oxford University

News 18  

The Indian Council of Medical Research has proposed to conduct a clinical trial for ‘randomised evaluation of COVID-19 therapy’ along with the University of Oxford and an expression of intent for participation in it has been sought from hospitals. The trial — ‘India-UK RECOVERY ’ — will be a multi-centre, adaptive platform trial on Covid patients, ICMR said on Friday. …

Monoclonal antibody treatment for COVID-19 could be a game changer
3 years, 6 months ago

Monoclonal antibody treatment for COVID-19 could be a game changer

The Hindu  

Monoclonal antibody treatment is now seen as a relatively effective and safer alternative in treating COVID-19 patients, with doctors stating that, as with any other drug, timing is very important for the administration of the therapy that’s touted as a game changer. “Monoclonal antibody treatment could prove to be a game changer in times to come if used at the …

Remember Donald Trump-touted hydroxychloroquine? Study in India backs it as Covid-19 cure
3 years, 6 months ago

Remember Donald Trump-touted hydroxychloroquine? Study in India backs it as Covid-19 cure

India Today  

Hydroxychloroquine, the malaria drug touted as a magical Covid-19 cure by former US President Donald Trump last year, has been found effective in a prophylactic study published in the Journal of The Association of Physicians of India last week. The study said, “hen adjusted for other risk factors, HCQ dose as per government recommendations, 2-3, 4-5, 6 or more weeks …

Does India's trial and error approach to fighting mutating coronavirus need course correction?
3 years, 7 months ago

Does India's trial and error approach to fighting mutating coronavirus need course correction?

India Today  

The second wave continues to wreak havoc in India with over 4,500 deaths recorded in a day on Wednesday. The Indian Council of Medical Research decision came within days of a study published in The Lancet that suggested plasma therapy did not improve survival or other pre-specified clinical outcomes in patients. Interestingly, similar data from ICMR's own trials was released …

Delete and control: On ICMR's dropping of plasma therapy
3 years, 7 months ago

Delete and control: On ICMR's dropping of plasma therapy

The Hindu  

The Indian Council of Medical Research has finally dropped its espousal of convalescent plasma therapy as treatment for moderate COVID-19 in its latest guidelines. Last year, the ICMR, in one of the definitive clinical trials in the world, demonstrated that CPT neither saved lives nor improved patient outcomes but was equivocal about it in public. This gave leeway to some …

Top medical experts welcome move to remove plasma therapy from COVID-19 treatment
3 years, 7 months ago

Top medical experts welcome move to remove plasma therapy from COVID-19 treatment

Deccan Chronicle  

New Delhi: Several top medical experts have welcomed the Indian Council of Medical Research 's updated advisory released on Monday dropping the use of convalescent plasma from recommended treatment protocols for COVID-19. Sir Ganga Ram Hospital chairman Dr DS Rana said plasma therapy has failed to change the "course of mortality" and asserted that some scientists are also of the …

Not enough evidence to prove plasma therapy works: Top ICMR scientist on why India changed treatment protocol
3 years, 7 months ago

Not enough evidence to prove plasma therapy works: Top ICMR scientist on why India changed treatment protocol

India Today  

The Centre on Monday revised the clinical guidance for Covid-19 treatment, dropping the off-label use of convalescent plasma from the treatment protocol for adult patients. Dr Samiran Panda, Indian Council of Medical Research scientist who was also a part of the panel that dropped plasma therapy from Covid-19 management guidelines, told India Today that the decision was taken since anecdotal …

Why government has dropped plasma therapy for Covid-19
3 years, 7 months ago

Why government has dropped plasma therapy for Covid-19

India Today  

India has officially removed the use of convalescent plasma, popularly known as the plasma therapy, on Covid-19 patients from its clinical management guidelines for the disease. The previous guidelines allowed “off label” use of plasma therapy on Covid-19 patients during moderate stage within seven days of the onset of symptoms. WHY GOVERNMENT DROPPED PLASMA THERAPY Many a time, the prescription …

Found Ineffective, Plasma Therapy No Longer Recommended For Covid-19 Treatment
3 years, 7 months ago

Found Ineffective, Plasma Therapy No Longer Recommended For Covid-19 Treatment

News 18  

Days after various studies and expert panels suggested that plasma therapy on Covid-19 patients was found ineffective in reducing the progression to severe disease or death, the treatment protocol has been dropped from the clinical management guidelines, sources said. In the letter, which was also marked to ICMR chief Balram Bhargava and AIIMS Director Randeep Guleria, public health professionals alleged …

Govt removes plasma therapy as treatment for Covid-19 among adults
3 years, 7 months ago

Govt removes plasma therapy as treatment for Covid-19 among adults

India Today  

A government-appointed task force on Covid-19 on Monday removed plasma therapy from the treatment protocol for adult Covid-19 patients. In the revised clinical guidelines for management of adult Covid-19 patients, use of convalescent plasma therapy has been removed even as an 'off label treatment. Until now, India's Covid-19 treatment protocol allowed 'off label' use of convalescent plasma therapy but only …

COVID-19: Plasma therapy not found effective, likely to be dropped from clinical management guidelines
3 years, 7 months ago

COVID-19: Plasma therapy not found effective, likely to be dropped from clinical management guidelines

Firstpost  

The present guidelines allows ‘off label’ use of plasma therapy at the stage of early moderate disease, that is, within seven days of the onset of symptoms New Delhi: Plasma therapy on COVID-19 patients has not been found effective in reducing the progression to severe disease or death and is likely to be dropped from the clinical management guidelines, sources …

Plasma therapy not effective, likely to be dropped from clinical management guidelines on Covid-19
3 years, 7 months ago

Plasma therapy not effective, likely to be dropped from clinical management guidelines on Covid-19

India Today  

Plasma therapy on Covid-19 patients has not been found effective in reducing the progression to severe disease or death and is likely to be dropped from the clinical management guidelines, sources said. In the letter, which was also marked to ICMR chief Balram Bhargava and AIIMS Director Randeep Guleria, public health professionals alleged that the current guidelines on plasma therapy …

Stop irrational use of plasma, may develop more virulent strains of Covid, warn experts
3 years, 7 months ago

Stop irrational use of plasma, may develop more virulent strains of Covid, warn experts

India Today  

A group of doctors, public health officials and experts have written to the Centre’s principal scientific advisor along with the AIIMS chief and ICMR chief, raising concerns over the “irrational and non-scientific use of convalescent plasma for Covid-19”. The letter addressed to Principal Scientific Advisor Dr Vijay Raghavan says, “We are writing to you as concerned clinicians, public health professionals …

WHO to restart Covid drug trial with focus on immune responses
3 years, 7 months ago

WHO to restart Covid drug trial with focus on immune responses

India TV News  

The World Health Organization is set to restart an international clinical trial of three existing drugs that can save the lives of people hospitalised with Covid-19. The latest trial will test three drugs that dampen inflammation -- Infliximab, Imatinib and Artesunate. And we need to study drugs that we can deliver in a broad group of countries," added Rottingen, who …

Do not use 'miracle cure' ivermectin on COVID-19 patients says WHO
3 years, 8 months ago

Do not use 'miracle cure' ivermectin on COVID-19 patients says WHO

Firstpost  

The World Health Organization said Wednesday that ivermectin — touted by some on social media as a Covid-19 “miracle cure” — should not be used to treat coronavirus patients. The WHO said: “We recommend not to use ivermectin in patients with Covid-19 except in the context of a clinical trial.” Facebook posts and articles endorsing ivermectin have proliferated in Brazil, …

Scientific disinterest: The Hindu Editorial on Union Health Minister’s presence at Coronil promotion event
3 years, 10 months ago

Scientific disinterest: The Hindu Editorial on Union Health Minister’s presence at Coronil promotion event

The Hindu  

The presence of Union Health Minister Harsh Vardhan at a press conference to promote Coronil, an Ayurvedic pill promoted by Baba Ramdev’s Patanjali Ayurved, is objectionable on more than one count. Dr Vardhan, alongside Cabinet colleague Nitin Gadkari, was at a press conference with Baba Ramdev and other promoters of Patanjali to announce a scientific publication describing the efficacy of …

Coronavirus | Clinical trials indicate India’s vaccines will be effective against COVID-19 variants: ICMR
3 years, 10 months ago

Coronavirus | Clinical trials indicate India’s vaccines will be effective against COVID-19 variants: ICMR

The Hindu  

Indian Council of Medical Research Director General Dr Balram Bhargava has said interim results of the ongoing clinical trials indicated that the indigenous Covid-19 vaccines would be effective against the mutated virus strains reported from the United Kingdom, South Africa and Brazil. In the case of the variants from South Africa and Brazil, efforts were on to isolate the mutated …

Study shows Covid-19 evolved during treatment, convalescent plasma therapy patients had UK mutant
3 years, 10 months ago

Study shows Covid-19 evolved during treatment, convalescent plasma therapy patients had UK mutant

India Today  

A recent study has revealed that the dominant variant of the novel coronavirus or Covid-19 that emerged in patients after the convalescent plasma therapy possessed a mutation that is also present in the one first discovered in the UK. ".data reveal strong selection on SARS-CoV-2 during convalescent plasma therapy associated with the emergence of viral variants with evidence of reduced …

Bharat Biotech, SII Approach DCGI for Using Covid Vaccine on Those Using Blood Thinners: ICMR DG
3 years, 10 months ago

Bharat Biotech, SII Approach DCGI for Using Covid Vaccine on Those Using Blood Thinners: ICMR DG

News 18  

ICMR chief Balram Bhargava on Thursday said COVID-19 vaccine manufacturers–Bharat Biotech and Serum Institute–have approached the country's drugs regulator to make changes in the fact sheet to permit the use of the vaccine on people using blood thinners. The relative contraindication regarding blood thinners is mentioned in the fact sheet of both the vaccines, Covaxin and Covishield, he said. Oxford …

Covishield and Covaxin safe for patients on blood thinners: ICMR chief
3 years, 10 months ago

Covishield and Covaxin safe for patients on blood thinners: ICMR chief

Live Mint  

Both the covid-19 vaccines Covishield and Covaxin approved for emergency use in India are safe for patients on blood thinners, Indian Council of Medical Research’s Director General Balram Bhargava said on Thursday. The ICMR chief said that the health ministry has written to the drug controller general of India and both the vaccine manufacturers to correct the factsheet that has …

Coronavirus | ICMR warns against indiscriminate use of convalescent plasma therapy
4 years, 1 month ago

Coronavirus | ICMR warns against indiscriminate use of convalescent plasma therapy

The Hindu  

The Indian Council of Medical Research has warned against indiscriminate use of convalescent plasma therapy for treating COVID-19. On Wednesday, it released report of an open-label phase II multicentre randomised controlled trial conducted across 39 public and private hospitals on the use of CPT in management of cases with moderate infection. The report concluded that the therapy “did not lead …

Indiscriminate Use of Convalescent Plasma Therapy in Covid Patients Not Advisable, Warns ICMR
4 years, 1 month ago

Indiscriminate Use of Convalescent Plasma Therapy in Covid Patients Not Advisable, Warns ICMR

News 18  

The country's apex health research body, ICMR, has issued an advisory statingthat indiscriminate use of convalescent plasma therapy in coronavirus infected patients is not advisable. In an "Evidence Based Advisory to address Inappropriate Use of Convalescent Plasma in COVID-19 Patients", the Indian Council of Medical Research said that a potential donor for convalescent plasma should have sufficient concentration of antibody …

Indiscriminate Use of Plasma Therapy Not Advisable: ICMR
4 years, 1 month ago

Indiscriminate Use of Plasma Therapy Not Advisable: ICMR

The Quint  

Experts in India have long called out the lack of evidence to support this treatment. Speaking to FIT, Dr Sumit Ray, Senior consultant of Critical Care Medicine, Holy Family Hospital, said, “The theoretical benefit of plasma therapy is in helping boost immunity if not enough is developed in the patient. But, the problem with COVID-19 is not of an inadequate …

Dutch Covid medicine made from blood plasma ready for use
4 years, 1 month ago

Dutch Covid medicine made from blood plasma ready for use

NL Times  

Blood bank Sanquin and plasma producer Sanquin Plasma Products produced 4 thousand doses of Covid-19 antibody treatment made from the blood plasma of recovered patients. The plasma medicine will first go towards preventing coronavirus infections in people with weakened immune systems, such as cancer patients and people who have just undergone an organ transplant. Minister Hugo de Jonge of Public …

Treatment Protocols Being Reassessed 10 Months into Covid-19 Pandemic, Focus on Aspirin as Potential Drug
4 years, 1 month ago

Treatment Protocols Being Reassessed 10 Months into Covid-19 Pandemic, Focus on Aspirin as Potential Drug

News 18  

“From today, aspirin will be investigated in the world’s largest clinical trial of treatments for patients hospitalised with COVID-19. The Randomised Evaluation of COVid-19 therapy trial is taking place in 176 hospital sites across the UK, and has so far recruited over 16,000 patients,” read the RECOVERY Trial’s web information page on Aspirin. This is the newest entrant in the …

The plasma dead end?
4 years, 2 months ago

The plasma dead end?

India Today  

Since ILBS Hospital, in New Delhi, inaugurated its plasma bank in early July, requests have poured in ceaselessly. Many examples of adverse reactions and the inability of plasma treatment to reduce Covid mortality have been recorded in the ICMR’s PLACID trial too. As a result, the ICMR has announced the possibility of removing convalescent plasma therapy as one of the …

Plasma Therapy Doesn't Reduce COVID Mortality: ICMR Study in BMJ
4 years, 2 months ago

Plasma Therapy Doesn't Reduce COVID Mortality: ICMR Study in BMJ

The Quint  

In India, the treatment first made news in mid-April when a patient in Delhi received experimental plasma therapy and was weaned off from ventilator support. Delhi’s Max Hospital gave a 49-year-old male COVID-19 patient plasma treatment on compassionate grounds. In the experimental treatment, antibodies from the blood of patients who have recovered from coronavirus are given to those battling the …

’Plasma therapy has saved lives of many including mine’: Jain on ICMR’s decision
4 years, 2 months ago

’Plasma therapy has saved lives of many including mine’: Jain on ICMR’s decision

Live Mint  

Delhi health minister Satyender Jain on Wednesday said that plasma therapy treatment has saved lives of many from the novel coronavirus in the past months, after the Indian Council of Medical Research on Tuesday said that it considers removing it from Covid-19 national treatment protocol. "Lives of more than 2000 people, including mine, have been saved through plasma therapy, so …

Mumbai local trains to allow women travellers from today; Centre mulls removing plasma therapy as treatment
4 years, 2 months ago

Mumbai local trains to allow women travellers from today; Centre mulls removing plasma therapy as treatment

Firstpost  

Currently only those engaged in frontline duties and falling in the essential staff category of the Maharashtra government are allowed to travel in the local trains run by Central Railway and Western Railway As daily coronavirus cases in India dropped below 50,000 for the first time in nearly three months, Railway minister Piyush Goyal announced that women passengers will be …

The Rise & Fall of Plasma Therapy as COVID-19 Treatment in India
4 years, 2 months ago

The Rise & Fall of Plasma Therapy as COVID-19 Treatment in India

The Quint  

On a daily basis, one gets at least two to three messages of desperate family members searching for a plasma donor for their loved ones battling COVID-19. Delhi set up a plasma bank in June to cater to the increasing demand of COVID-19 patients, with several states following the example. In June, the Union Health Ministry, in their clinical guidelines …

Remdesivir useless in covid fight: WHO
4 years, 2 months ago

Remdesivir useless in covid fight: WHO

Live Mint  

A World Health Organization trial of Gilead Sciences Inc.’s remdesivir, the antiviral drug used to treat US President Donald Trump, showed little or no effect on the survival rates of covid patients, a result that is in variance with the trial reports of the drugmaker. The WHO trial, which also studied the effect of hydroxychloroquine, a combination of HIV drugs …

WHO Solidarity Trials find Remdesivir, HCQ, HIV drug, interferon ineffective in treating COVID-19
4 years, 2 months ago

WHO Solidarity Trials find Remdesivir, HCQ, HIV drug, interferon ineffective in treating COVID-19

Firstpost  

The WHO’s Solidarity Therapeutics Trial was conducted in 11,266 adult patients in 405 hospitals across more than 30 countries. The World Health Organization’s Solidarity trial is the world’s largest ongoing randomized control trial of potential COVID-19 therapeutics. Based on data collected from the trial, the WHO has released an interim report of patients’ responses to repurposed drugs for COVID-19 treatment. …

WHO trial results show remdesivir has little or no effect for covid-19 patients
4 years, 2 months ago

WHO trial results show remdesivir has little or no effect for covid-19 patients

Live Mint  

Interim results from the World Health Organization’s solidarity trial showed that Gilead Sciences Inc’s remdesivir showed little or no effect for covid-19 patients, a result which was significantly different from the positive results shown by Gilead’s own trial. “These remdesivir, hydroxychloroquine, lopinavir and interferon regimens appeared to have little or no effect on hospitalized covid-19 patients, as indicated by overall …

Coronavirus | Repurposed drugs did not cut down mortality, says WHO
4 years, 2 months ago

Coronavirus | Repurposed drugs did not cut down mortality, says WHO

The Hindu  

Interim results from the Solidarity Therapeutics Trial, coordinated by the World Health Organization, have indicated that remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon regimens appeared to have little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalised patients as per information released by the World Health Organisation. Speaking exclusively to The Hindu, about the outcome Prof. K …

WHO trial finds remdesivir has little effect on COVID-19
4 years, 2 months ago

WHO trial finds remdesivir has little effect on COVID-19

Al Jazeera  

Early results from large, randomised trial suggest antiviral does little to reduce mortality rates or time in hospital. A World Health Organization trial using four drugs including the antiviral remdesivir in the hospital treatment of COVID-19 has found the repurposed medicines have little to no effect on the length of time patients spend in hospital or their survival. “These Remdesivir, …

Hydroxycloroquine does not help with Covid mortality; Improves ICU risk
4 years, 2 months ago

Hydroxycloroquine does not help with Covid mortality; Improves ICU risk

NL Times  

Hydroxychloroquine, a malaria drug often used to treat Covid-19, does not have a noticeable effect on the mortality rate of the coronavirus, according to a study by 14 Dutch hospitals. The hospitals analyzed 1,064 Covid-19 patients in 14 hospitals, 189 of whom were treated with hydroxychloroquine, 377 were treated with chloroquine, and 498 were not treated with either of the …

Anti-malaria drug hydroxychloroquine ineffective against coronavirus, reveal UK RECOVERY Trials
4 years, 2 months ago

Anti-malaria drug hydroxychloroquine ineffective against coronavirus, reveal UK RECOVERY Trials

Firstpost  

The results of the study, published by NEJM, showed that COVID-19 patients who did not need mechanical ventilation to begin with had a higher likelihood of needing ventilation or dying when they were put on hydroxychloroquine Hydroxychloroquine is no better than usual care in reducing the chances of death in COVID-19 patients, suggest the results of RECOVERY Trials published Thursday …

DCGI Nod to Phase-1 Human Trials of 'Antisera' with Potential to Treat Covid-19
4 years, 2 months ago

DCGI Nod to Phase-1 Human Trials of 'Antisera' with Potential to Treat Covid-19

News 18  

The Drugs Controller General of India has given permission for conducting Phase-1 human clinical trial for an "antisera" that was developed by injecting inactivated SARS-CoV-2 in horses and can be a potential treatment for COVID-19, ICMR officials said on Tuesday. "With Biological E Limited we have developed an horse 'antisera' and we have just got clearance for conducting clinical trials …

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