Pfizer says bivalent booster increases antibodies for Omicron variants
2 years, 2 months ago

Pfizer says bivalent booster increases antibodies for Omicron variants

LA Times  

Pfizer Inc. and its German vaccine partner BioNTech said their new COVID-19 booster designed to target the dominant Omicron subvariant produced more antibodies against the intended strains than did the original version of the shot. Pfizer and BioNTech plan to release additional data on the COVID-19 shots in the coming weeks to measure immune responses one month after administration of the new bivalent booster, which also targets the original coronavirus strain. “While we expect more mature immune-response data from the clinical trial of our Omicron BA.4/BA.5-adapted bivalent vaccine in the coming weeks, we are pleased to see encouraging responses just one week after vaccination in younger and older adults,” Pfizer Chief Executive Albert Bourla said in the statement. “These early data suggest that our bivalent vaccine is anticipated to provide better protection against currently circulating variants than the original vaccine, and potentially help to curb future surges in cases this winter.” The vaccine partners studied two cohorts that had been given the new vaccine: one comprised those ages 18 to 55, the other those 55 and up.

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History of this topic

FDA advisers urge targeting JN.1 strain in recipe for fall’s COVID vaccines
6 months, 2 weeks ago

FDA advisers urge targeting JN.1 strain in recipe for fall’s COVID vaccines

Associated Press  

WASHINGTON — Government advisers Wednesday said it’s time to update the recipe for the COVID-19 vaccines Americans will receive in the fall -- targeting a version of the ever-evolving coronavirus called JN.1. But just a few months later, numerous offshoots of JN.1 already are on the rise, prompting Moderna and Pfizer to also test a slightly different vaccine formula targeting …

New COVID-19 vaccines available in Australia: Millions urged to get a booster as cases rise
1 year ago

New COVID-19 vaccines available in Australia: Millions urged to get a booster as cases rise

Daily Mail  

New COVID-19 vaccines targeting the current Omicron variant of the virus are available in community pharmacies throughout Australia. Pharmacy Guild of Australia National President Trent Twomey says the new vaccine available on Monday is targeted at the strain of the virus which is currently circulating among the population. 'With COVID-19 cases on the rise, it is important anyone who is …

What To Know About New COVID Boosters And Who Is Eligible
1 year, 3 months ago

What To Know About New COVID Boosters And Who Is Eligible

Huff Post  

aire images via Getty Images “The vaccines are our single best method to protect ourselves from COVID, to protect our friends, family, loved ones, classmates, co-workers, etcetera, from COVID,” said Dr. S. Wesley Long. the way to think about these new COVID vaccines is it’s really like the annual flu shot,” Long said. “The recommendation from CDC’s advisory committee will …

US FDA authorizes Pfizer-BioNTech, Moderna's updated Covid shots
1 year, 3 months ago

US FDA authorizes Pfizer-BioNTech, Moderna's updated Covid shots

India Today  

The U.S. Food and Drug Administration on Monday authorized updated Covid-19 vaccines from Pfizer/BioNTech and Moderna that target a recently circulating Omicron variant of the coronavirus, paving the way for the launch later this week of a fall vaccination campaign. Pfizer and Moderna said their updated vaccines, which target the XBB.1.5 subvariant of the virus, were expected to be available …

CBS News poll finds less concern about new COVID variants now than with Omicron
1 year, 3 months ago

CBS News poll finds less concern about new COVID variants now than with Omicron

CBS News  

Despite a recent rise in COVID cases and new variants, most Americans aren't concerned about getting COVID. There is less concern specifically about new variants today than there was about the Omicron variant as it was emerging in late 2021. As has long been the case with the coronavirus, concern, attention and action are all connected: 40% report following news …

U.S. approves updated COVID vaccines to rev up protection this fall
1 year, 3 months ago

U.S. approves updated COVID vaccines to rev up protection this fall

The Hindu  

The U.S. approved updated COVID-19 vaccines Monday, hoping to rev up protection against the latest coronavirus strains and blunt any surge this fall and winter. It’s part of a shift to treat fall updates of the COVID-19 vaccine much like getting a yearly flu shot. “Vaccination remains critical to public health and continued protection against serious consequences of COVID-19, including …

US approves updated COVID vaccines to rev up protection this fall
1 year, 3 months ago

US approves updated COVID vaccines to rev up protection this fall

Associated Press  

WASHINGTON — The U.S. approved updated COVID-19 vaccines Monday, hoping to rev up protection against the latest coronavirus strains and blunt any surge this fall and winter. It’s part of a shift to treat fall updates of the COVID-19 vaccine much like getting a yearly flu shot. “Vaccination remains critical to public health and continued protection against serious consequences of …

Should you get the new COVID booster? The CDC is about to decide
1 year, 3 months ago

Should you get the new COVID booster? The CDC is about to decide

LA Times  

A nurse prepares a syringe of a COVID-19 vaccine. The CDC’s vaccine advisors will soon decide whether to recommend the latest COVID-19 boosters only for frail, older, sick and immunocompromised people or to offer it to everyone over 6 months of age. “I don’t plan to get it myself,” said Dr. Paul Offit, the director of the Vaccine Education Center …

FDA approves updated COVID vaccines to rev up protection this fall
1 year, 3 months ago

FDA approves updated COVID vaccines to rev up protection this fall

LA Times  

Single-dose vials of Pfizer’s updated COVID vaccine for adults, which was approved by U.S. regulators on Monday. The U.S. approved updated COVID-19 vaccines Monday, hoping to rev up protection against the latest coronavirus strains and blunt any surge this fall and winter. “Vaccination remains critical to public health and continued protection against serious consequences of COVID-19, including hospitalization and death,” …

FDA vaccine adviser Dr Paul Offit says healthy young people don't need another Covid booster - despite new BA.2.86 variant pushing virus rates up
1 year, 3 months ago

FDA vaccine adviser Dr Paul Offit says healthy young people don't need another Covid booster - despite new BA.2.86 variant pushing virus rates up

Daily Mail  

Most Americans don't need another Covid booster shot, according to one of the Food and Drug Administration's top vaccine advisers. Dr Paul Offit, an internationally recognized vaccines expert, said healthy young people did not need to get the updated Covid booster this fall He added: 'Boosting otherwise healthy young people is a low-risk, low-reward strategy. Dr Offit, who is based …

Moderna says updated COVID vaccine is effective against ‘highly-mutated’ BA.2.86 variant
1 year, 3 months ago

Moderna says updated COVID vaccine is effective against ‘highly-mutated’ BA.2.86 variant

Hindustan Times  

Moderna on Wednesday said clinical trial data showed its updated COVID-19 vaccine will likely be effective against the highly-mutated BA.2.86 subvariant of the coronavirus that has raised fears of a resurgence of infections. The Omicron offshoot carries more than 35 mutations in key portions of the virus compared with XBB.1.5, the dominant variant through most of 2023 and the target …

Next round of COVID-19 shots in fall will target latest omicron strain
1 year, 6 months ago

Next round of COVID-19 shots in fall will target latest omicron strain

Associated Press  

NEW YORK — The next round of COVID-19 vaccines will target one of the latest versions of the coronavirus, the Food and Drug Administration said Friday. The agency told vaccine makers to provide protection against just one omicron strain, known as XBB.1.5. The three U.S. companies that make COVID-19 shots said this week they had geared up to make the …

FDA advisers endorse updating COVID vaccines to target latest omicron strain
1 year, 6 months ago

FDA advisers endorse updating COVID vaccines to target latest omicron strain

Associated Press  

The COVID-19 vaccines are on track for a big recipe change this fall. Today’s vaccines still contain the original coronavirus strain, the one that started the pandemic — even though that was long ago supplanted by mutated versions as the virus rapidly evolves. While infections have declined, the virus could be a real concern next winter, FDA’s vaccine chief Dr. …

COVID vaccine should be updated to target XBB strain, FDA committee says
1 year, 6 months ago

COVID vaccine should be updated to target XBB strain, FDA committee says

LA Times  

Commuters with and without face masks walk through Union Station in Los Angeles in December. The unanimous recommendation from the Food and Drug Administration’s vaccine advisory committee follows that of agency staff, who in a memo acknowledged that while older vaccine formulas can still help stave off severe disease, “protection wanes with time and is reduced against subsequent waves of …

An FDA panel meets about which COVID strains the U.S. will target with vaccines
1 year, 6 months ago

An FDA panel meets about which COVID strains the U.S. will target with vaccines

NPR  

An FDA panel meets about which COVID strains the U.S. will target with vaccines An advisory committee to the Food and Drug Administration meets to discuss the COVID strains that vaccines in the U.S. will target this fall. ARI SHAPIRO, HOST: Updated COVID vaccines are coming this fall, and they'll likely target a variant that's circulating now. HUANG: Yeah, you …

FDA advisers back updated COVID shots for fall vaccinations
1 year, 6 months ago

FDA advisers back updated COVID shots for fall vaccinations

NPR  

FDA advisers back updated COVID shots for fall vaccinations Enlarge this image toggle caption Esteban Felix/AP Esteban Felix/AP A panel of expert advisers to the Food and Drug Administration voted unanimously Thursday to recommend that the COVID-19 vaccine be updated to target emerging subvariants of omicron. The COVID shot that's currently available is known as a "bivalent" vaccine because it …

Extra COVID-19 booster now open to some high-risk Americans
1 year, 8 months ago

Extra COVID-19 booster now open to some high-risk Americans

Associated Press  

WASHINGTON — Older Americans and people with weak immune systems can get an extra COVID-19 booster dose this spring. From now on, anyone getting a Pfizer or Moderna dose — whether it’s a booster or their first-ever vaccination — will get an updated version rather than the outdated original shots. People 65 or older who already had one Pfizer or …

CDC signs off on additional Covid-19 booster doses for certain people
1 year, 8 months ago

CDC signs off on additional Covid-19 booster doses for certain people

CNN  

CNN — The US Centers for Disease Control and Prevention updated its recommendations on the Covid-19 vaccines on Wednesday to allow another dose of the bivalent booster for people who are 65 and older or who have weakened immune systems and who “want the option of added protection” against the coronavirus. The move aligns with Tuesday’s US Food and Drug …

Extra spring COVID booster cleared for certain Americans
1 year, 8 months ago

Extra spring COVID booster cleared for certain Americans

LA Times  

On Tuesday, regulators cleared another booster dose for older adults and people with weak immune systems so they can shore up protection this spring. U.S. regulators on Tuesday cleared another COVID-19 booster dose for older adults and people with weak immune systems so they can shore up protection this spring — while taking steps to make the vaccinations simpler for …

Pfizer Bivalent Vaccine Reduces Covid-related Death Risk by 68 Pc in Older People: Study
1 year, 8 months ago

Pfizer Bivalent Vaccine Reduces Covid-related Death Risk by 68 Pc in Older People: Study

News 18  

Vulnerable people aged 65 years and over receiving the Pfizer bivalent mRNA vaccine booster dose showed 72 per cent lower risk of Covid-related hospitalisation and 68 per cent lower risk of Covid-related death, according to a new study published in the journal The Lancet Infectious Diseases. Israel has prioritised bivalent mRNA booster vaccines for people at high risk of severe …

The COVID virus has mutated so much since 2019 that some experts say it should be renamed SARS-CoV-3
1 year, 8 months ago

The COVID virus has mutated so much since 2019 that some experts say it should be renamed SARS-CoV-3

Salon  

On Monday, April 10, President Joe Biden signed a bill that immediately terminated the COVID-19 national emergency, first enacted in 2020 as the SARS-CoV-2 virus gripped the country. "This virus remains unstable — it has not settled into a predictable pattern, which means surveillance systems need to be sensitive to pick up the early signs of another surge." Related Pandemic …

No need for booster vaccine against coronavirus this spring, experts decide
1 year, 9 months ago

No need for booster vaccine against coronavirus this spring, experts decide

Dutch News  

Coronavirus experts have advised against another round of vaccinations this spring because there is enough immunity in the population from previous vaccines or infections. The advisers will decide later in the year whether there should be another booster round in the autumn, when the peak season for coronavirus infections begins. Doctors should still be able to prescribe a vaccine for …

No need for booster vaccine against coronavirus this spring, experts decide
1 year, 9 months ago

No need for booster vaccine against coronavirus this spring, experts decide

Dutch News  

Coronavirus experts have advised against another round of vaccinations this spring because there is enough immunity in the population from previous vaccines or infections. The advisers will decide later in the year whether there should be another booster round in the autumn, when the peak season for coronavirus infections begins. Doctors should still be able to prescribe a vaccine for …

Protein-based booster shots help fight Omicron
1 year, 10 months ago

Protein-based booster shots help fight Omicron

China Daily  

A woman receives a booster dose in Chaoyang district of Beijing on July 13, 2022. China has recently rolled out two protein-based COVID-19 vaccines to serve as booster shots against Omicron subvariants, bringing new weapons to China's fight against mutated strains of the virus. The two vaccines are also recommended as a booster for those inoculated with three inactivated vaccines, …

Australian adults will be able to get fifth dose of COVID-19 vaccine later this month
1 year, 10 months ago

Australian adults will be able to get fifth dose of COVID-19 vaccine later this month

ABC  

Australian adults will be able to get a fifth dose of the COVID-19 vaccine within a fortnight, after the federal government accepted advice from its expert vaccine advisory body. Key points: From February 20, people 18 and over who have not had a COVID-19 vaccine or positive case in the last six months are eligible for another shot Uptake of …

FDA advisers set to consider one-and-done annual covid booster plan
1 year, 10 months ago

FDA advisers set to consider one-and-done annual covid booster plan

Live Mint  

The message has come through loud and clear that Americans have already had enough of frequent Covid shots. The new strategy would require health officials to meet each year to review which strains of the virus should be included in the shots, just as they do with flu, for use in September. “I don’t think that we can chase after …

FDA’s advisors back plan to simplify COVID-19 vaccinations
1 year, 10 months ago

FDA’s advisors back plan to simplify COVID-19 vaccinations

LA Times  

Syringes with COVDI-19 vaccines are prepared at a free public clinic in Lynwood last year. “We’re still protected against severe disease, thank goodness,” even after the latest Omicron strains cropped up, said FDA advisor Dr. Paul Offit, a vaccine expert at Children’s Hospital of Philadelphia. The first step: The FDA advisory panel voted unanimously that people should get the same …

FDA proposes once-a-year COVID-19 shots for most Americans
1 year, 11 months ago

FDA proposes once-a-year COVID-19 shots for most Americans

LA Times  

U.S. health officials are proposing a simplified approach to COVID-19 vaccinations for most adults and children. That baseline of protection should be enough to move to an annual booster against the latest strains in circulation and make COVID-19 vaccinations more like the yearly flu shot, according to the agency. FDA scientists and vaccine companies would study vaccination, infection rates and …

FDA vaccine advisers ‘disappointed’ and ‘angry’ that early data about new Covid-19 booster shot wasn’t presented for review last year
1 year, 11 months ago

FDA vaccine advisers ‘disappointed’ and ‘angry’ that early data about new Covid-19 booster shot wasn’t presented for review last year

CNN  

CNN — Some vaccine advisers to the federal government say they’re “disappointed” and “angry” that government scientists and the pharmaceutical company Moderna didn’t present a set of infection data on the company’s new Covid-19 booster during meetings last year when the advisers discussed whether the shot should be authorized and made available to the public. Video Ad Feedback 'Outrageous': Bernie …

India Saw Over 294 Omicron Variants in 2022, Not One Could Survive Here; Booster Shot Wise Call: INSACOG Co-Chair
1 year, 11 months ago

India Saw Over 294 Omicron Variants in 2022, Not One Could Survive Here; Booster Shot Wise Call: INSACOG Co-Chair

News 18  

Around 300 sub-variants of Omicron were detected in India last year, but not one was able to establish itself here as a variant of concern, the co-chair of India’s coronavirus genomic surveillance programme told News18.com. Practically, India has witnessed almost every variant of Omicron, but none of those was able to establish itself in India, while the variants caused havoc …

First real-world data show Omicron booster kept seniors out of hospitals
1 year, 11 months ago

First real-world data show Omicron booster kept seniors out of hospitals

LA Times  

Vials of Pfizer and BioNTech’s Omicron-targeting COVID-19 vaccine are seen on a production line at a manufacturing facility in Kalamazoo, Mich. In the first real-world test of vaccine boosters specially designed to protect against the Omicron variant, Israeli researchers have found that people 65 and older who got an updated jab were 81% less likely to be hospitalized with COVID-19 …

'Consider 2nd Booster': A Request Given to Mansukh Mandaviya During Covid-19 Meeting with Doctors
1 year, 11 months ago

'Consider 2nd Booster': A Request Given to Mansukh Mandaviya During Covid-19 Meeting with Doctors

News 18  

Union health minister Mansukh Mandaviya has been urged to consider a second booster dose for Covid-19, especially for healthcare workers and frontline workers. According to a Deutsche Welle article published in January, a study conducted in Israel suggested that fourth dose of the coronavirus vaccine does not offer significant protection from the Omicron variant. Sarah Fortune, John LaPorte Given Professor …

Omicron boosters for the youngest children are here. Will they make a difference?
1 year, 11 months ago

Omicron boosters for the youngest children are here. Will they make a difference?

LA Times  

Updated COVID-19 booster shots are now available for the youngest children in California, a welcome development for officials hoping to augment vaccine coverage and head off a viral resurgence this winter. “We’re always concerned with lower vaccination rates among children,” said Los Angeles County Public Health Director Barbara Ferrer, “in particular because, as we’ve seen, some children will still get …

New Omicron sub-variant is mild: Doctors
2 years ago

New Omicron sub-variant is mild: Doctors

Deccan Chronicle  

HYDERABAD: The Omicron sub-variant BF.7 wave will be milder than those caused by previous variants, according to city doctors, and there is no cause to fear with people having developed strong immunity both due to the Covid vaccine and numerous variants spreading in communities. Given the threat of the new variant that is quickly spreading in China and its projected …

Your Best Shot at Fighting Covid: 28% Have Already Taken Booster Dose, Finds Survey
2 years ago

Your Best Shot at Fighting Covid: 28% Have Already Taken Booster Dose, Finds Survey

News 18  

Amid government’s reminders for vaccine boosters in the wake of the Covid uptick in China, 28% of those surveyed by Localcircles said that they “have already taken the booster dose". However, 53% said that they “have not taken the booster dose and do not have any plans of taking it either". After the Centre’s meeting on Wednesday, Niti Aayog’s VK …

COVID-19: no need for scaremongering, precautions needed, say health experts
2 years ago

COVID-19: no need for scaremongering, precautions needed, say health experts

The Hindu  

Even as the Central and State governments have called for a general alert over a possible rise in COVID-19 cases, public health experts have warned against scaremongering over COVID-19. Public health experts point out that as the new virus variants coming into circulation are the sub variants of Omicron, which in itself was less lethal than Delta, there was no …

FDA clears updated COVID-19 vaccines for kids under age 5
2 years ago

FDA clears updated COVID-19 vaccines for kids under age 5

LA Times  

Nora Burlingame, 3, is held by her mother, Dina Burlingame, as she celebrates with nurse Luann Majeed after getting a dose of COVID-19 vaccine in June. U.S. regulators on Thursday cleared doses of the updated COVID-19 vaccines for children younger than 5. The FDA decided that: • Children under age 6 who’ve already gotten two original doses of Moderna’s COVID-19 …

Pfizer asks FDA to clear updated COVID shot for kids under 5
2 years ago

Pfizer asks FDA to clear updated COVID shot for kids under 5

LA Times  

A nurse in Seattle gives a dose of Pfizer’s original COVID-19 vaccine shot to a 20-month-old child in June. Pfizer is asking U.S. regulators to authorize its updated COVID-19 vaccine for the initial series of shots for children under age 5. Pfizer is asking U.S. regulators to authorize its updated COVID-19 vaccine for children under age 5 — not as …

As COVID-19 spikes in California, booster shots could make all the difference
2 years ago

As COVID-19 spikes in California, booster shots could make all the difference

LA Times  

With coronavirus cases and hospitalizations rising in Los Angeles County, officials are voicing new confidence in the effectiveness of the updated COVID-19 booster shot. New data has found that the updated COVID-19 vaccines offer “significant additional protection” against symptomatic infection in people who were previously vaccinated or boosted with the older formula. “We have seen very low uptake of the …

US renews push for COVID boosters as data show they protect
2 years, 1 month ago

US renews push for COVID boosters as data show they protect

Associated Press  

Americans who got the updated COVID-19 booster shots are better protected against symptomatic infection than those who haven’t — at least for now, U.S. health officials said Tuesday. Speaking at a White House briefing expected to be his last before he retires from the government at the end of year, Fauci said what “may be the final message I give …

Pfizer booster spurs immune response to new Omicron subvariants
2 years, 1 month ago

Pfizer booster spurs immune response to new Omicron subvariants

LA Times  

Pfizer’s updated boosters aren’t an exact match to the newest Omicron subvariants, but lab tests suggest they may offer some cross-protection, the company says. Pfizer said this week that its updated COVID-19 booster may offer some protection against newly emerging Omicron subvariants, even though it’s not an exact match to them. Americans have been reluctant to get the updated boosters …

Pfizer study says updated COVID boosters rev up antibody protection
2 years, 1 month ago

Pfizer study says updated COVID boosters rev up antibody protection

LA Times  

Booster shots of the Pfizer COVID-19 vaccine sit ready to be used at a vaccine clinic in Townshend, Vt. Pfizer’s updated COVID-19 booster significantly revved up adults’ virus-fighting antibodies, the company said Friday, releasing early findings from a rigorous study of the new shots. Pfizer said people 55 and older who got the Omicron-targeting booster had four-fold higher antibody levels …

New Omicron Variants Not Causing Significant Rise in Hospitalisations, Say Experts
2 years, 1 month ago

New Omicron Variants Not Causing Significant Rise in Hospitalisations, Say Experts

News 18  

The new variants of Omicron, XXB and BQ.1, have not led to any significant rise in coronavirus infections and hospitalisations in Maharashtra, experts have said. Dr Anita Mathew, Infectious Disease Specialist at Fortis Hospital, Mulund, said many of the new patients are asymptomatic. The department had also cautioned that coronavirus cases could rise during winter and the festive season, citing …

How Pfizer plans to sell its Covid vaccine back to YOU with a 10,000% markup
2 years, 1 month ago

How Pfizer plans to sell its Covid vaccine back to YOU with a 10,000% markup

Daily Mail  

Pfizer has been accused of 'daylight robbery' after it emerged the company plans to sell its Covid shot with an estimated 10,000 percent markup in the US next year — despite enjoying extraordinary surges in profits during the pandemic. Dr Ugur Sahin, the brains behind the Covid shot and CEO of Pfizer's German partner BioNTech, is among nine 'vaccine billionaires' …

New bivalent Covid vaccines DON'T give people better immunity, studies show
2 years, 1 month ago

New bivalent Covid vaccines DON'T give people better immunity, studies show

Daily Mail  

The new bivalent Covid vaccines are no more effective than the original shots, according to two new studies. In both studies, people who had already been triple vaccinated were given either a standard Covid shot or an updated bivalent booster. President Joe Biden got his updated booster yesterday — his fifth shot to date — in the latest White House …

Covid booster shot campaign opens to everyone 12 and up
2 years, 1 month ago

Covid booster shot campaign opens to everyone 12 and up

NL Times  

Everyone aged 12 and older can now make an appointment for a repeat vaccination against the coronavirus, the RIVM and GGD reported. That means that everyone who qualifies for the booster shot can get one at a vaccination location. People aged 12 and older can get the repeat vaccination if it has been at least three months since their previous …

Covid boosters available to everyone in their thirties and older
2 years, 2 months ago

Covid boosters available to everyone in their thirties and older

NL Times  

People who were born in 1992 or earlier can now make an appointment for another Covid-19 booster shot, the RIVM said. It also includes those people who were born in the last week of October, as well as November and December of 1992, and are thus still 29 years of age. Last week the vaccine appointments began to open up …

EMA gives positive advice over Covid-19 vaccines for children from 6 months
2 years, 2 months ago

EMA gives positive advice over Covid-19 vaccines for children from 6 months

NL Times  

The European Medicines Agency advised the European Commission to approve the Covid-19 vaccines produced by Pfizer and Moderna for use in children from six months old. Currently, Pfizer's vaccine is only allowed for children once they reach five years of age, and the Moderna vaccine can be given to children as young as six years old. Children from six months …

Updated COVID boosters are now available for kids. Here’s how to get them
2 years, 2 months ago

Updated COVID boosters are now available for kids. Here’s how to get them

LA Times  

Felix Johnstone, of Altadena, with mother Caitlin Johnstone, right, receives a child’s dose of the Pfizer-BioNTech COVID-19 vaccine from registered nurse Shirley Alfonso at Eugene A. Obregon Park in Los Angeles on Nov. 3, 2021. “As is true of the other COVID-19 vaccine and booster doses, the updated boosters were designed to protect individuals from the worst outcomes of COVID-19, …

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