How Much Should You Be Paid to Be Infected With Covid-19? Researchers Debate Ethics
3 years, 11 months ago

How Much Should You Be Paid to Be Infected With Covid-19? Researchers Debate Ethics

News 18  

Healthy people volunteering to be infected with SARS-CoV-2, in order to help scientists better understand how to tackle the virus, should receive payment if it is determined that these studies are otherwise ethical to proceed, new research suggests. The researchers assessed the ethics of paying participants to take part in the so-called ‘Human Infection Challenge Studies’ and said that they do not necessarily endorse the use of HICS for Covid-19. “Our work was spurred by concerns that payment for SARS-CoV-2 HICS might require a novel ethical framework, which we ultimately determined to be unfounded,” said lead author Holly Fernandez Lynch from the University of Pennsylvania. “Payment for HICS participation should be treated like payment in other clinical studies involving healthy participants,” Lynch added. For the study, published in the journal American Journal of Bioethics, the research team created a framework for scientists to follow in order to ethically assess payments for people taking part in HICS.

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History of this topic

No extra money for Long Covid research will "set patients back"
1 month ago

No extra money for Long Covid research will "set patients back"

Dutch News  

Patient organisations have said they are worried MPs will vote against a €21 million investment in clinical research into Long Covid symptoms on Thursday. PostCovidNL and Long Covid Nederland said the additional money is needed to provide a scientific base for treatment with existing medications which can alleviate the symptoms of some 500,000 sufferers in the short term. But PostCovid …

Unlike clinical trials, new Covid-19 study needed only a few volunteers
3 years, 4 months ago

Unlike clinical trials, new Covid-19 study needed only a few volunteers

Live Mint  

Medical studies often use thousands of volunteers. Researchers in the U.K. have deliberately infected 30 volunteers with the virus that causes Covid-19, in the first human challenge study of the disease. The volunteers are under 24-hour study in a hospital residential facility, allowing the researchers to, among other things, measure their viral load twice daily in the nose and throat, …

UK Study That Will Infect Volunteers With Covid-19 Approved
3 years, 10 months ago

UK Study That Will Infect Volunteers With Covid-19 Approved

News 18  

A study which will expose volunteers to the coronavirus is to begin in Britain within a month after it gained approval from the country’s clinical ethics body, the government said on Wednesday. “While there has been very positive progress in vaccine development, we want to find the best and most effective vaccines for use over the longer term,” Business Secretary …

Should People Be Compensated For Getting A COVID-19 Vaccine?
3 years, 11 months ago

Should People Be Compensated For Getting A COVID-19 Vaccine?

NPR  

Should People Be Compensated For Getting A COVID-19 Vaccine? URI BERLINER, BYLINE: Robert Litan worries that appeals from politicians and celebrities that implore people to get vaccinated, they won't be enough, so cash payouts should be a Plan B. Litan, an economist affiliated with the Brookings Institution, says that could be what it takes to reach herd immunity. BERLINER: He's …

Centre announced $120 million grant for coronavirus vaccine research: Harsh Vardhan
4 years, 1 month ago

Centre announced $120 million grant for coronavirus vaccine research: Harsh Vardhan

India Today  

The government has announced a $120 million grant for coronavirus vaccine research, Union health minister Harsh Vardhan said during the 8th BRICS STI ministerial meeting on Friday. Our govt has announced USD 120 million grant for COVID-19 vaccine research. The grant doesn't cover actual cost of vaccine & its distribution expenses which will be made available as & when a …

Activists urge ’Big Pharma’ to be transparent on COVID-19 vaccine costs
4 years, 2 months ago

Activists urge ’Big Pharma’ to be transparent on COVID-19 vaccine costs

Live Mint  

Activists called on pharmaceutical companies on Thursday to be transparent about the costs and terms of providing COVID-19 vaccines, saying they must be available and affordable for all. French drugmaker Sanofi and Britain's GlaxoSmithKline said on Wednesday they would supply 200 million doses of their COVID-19 candidate vaccine to the global COVAX vaccine facility backed by the World Health Organization …

U.K. Preparing COVID-19 Vaccine Trials That Deliberately Expose Study Subjects
4 years, 2 months ago

U.K. Preparing COVID-19 Vaccine Trials That Deliberately Expose Study Subjects

NPR  

Preparing COVID-19 Vaccine Trials That Deliberately Expose Study Subjects Enlarge this image toggle caption Kirsty O'Connor/PA Images via Getty Images Kirsty O'Connor/PA Images via Getty Images Updated at 9:00 a.m. ET Researchers in Britain are preparing to start a controversial COVID-19 "human challenge" study in which dozens of healthy volunteers will be exposed to live coronavirus in an effort to …

Infecting volunteers with coronavirus may be one way to test potential vaccines. But there are risks
4 years, 2 months ago

Infecting volunteers with coronavirus may be one way to test potential vaccines. But there are risks

ABC  

Researchers are considering using "human challenge studies" to accelerate COVID-19 vaccine research and development. However, if the first vaccines fail, or turn out to be only moderately effective, challenge studies could be used to select the next most promising candidates for future field trials. Members of WHO's science group agreed on a number of technical requirements for COVID-19 challenge studies …

US eyes controversial human challenge trials for COVID-19 vaccine
4 years, 4 months ago

US eyes controversial human challenge trials for COVID-19 vaccine

Al Jazeera  

The synthetic strain would be used in studies where patients are purposely infected to test a vaccine’s efficacy. US government scientists have begun efforts to manufacture a strain of the novel coronavirus that could be used in human challenge trials of vaccines, a controversial type of study in which healthy volunteers would be vaccinated and then intentionally infected with the …

ICMR's COVID-19 vaccine symposium saw experts discuss challenge trials, vaccine distribution, preparedness
4 years, 5 months ago

ICMR's COVID-19 vaccine symposium saw experts discuss challenge trials, vaccine distribution, preparedness

Firstpost  

Many experts outlined that big investments in trials and vaccine development need to be accompanied by big investments in science. The Indian Council of Medical Research hosted an international symposium on 30 July, bringing global health and vaccine experts under one roof to discuss science & ethics around COVID-19 vaccines. “Our collaborations with both GAVI and WHO will enable not …

Human Challenge Trial Neither Essential Nor Ethically Justified at This Time, Says US Expert Anthony Fauci
4 years, 5 months ago

Human Challenge Trial Neither Essential Nor Ethically Justified at This Time, Says US Expert Anthony Fauci

News 18  

Human challenge trials to test Covid-19 vaccines are not necessary at this time as randomised controlled trials are quite feasible owing to the high incidence of the infectious disease, said Dr Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases in the US. These factors have led us to conclude that human challenge trials are not essential …

Infecting willing volunteers with Covid-19 might speed up the race for a vaccine. But it could be risky. (Opinion)
4 years, 5 months ago

Infecting willing volunteers with Covid-19 might speed up the race for a vaccine. But it could be risky. (Opinion)

CNN  

Editor’s Note: Robert Klitzman is a professor of psychiatry and director of the masters in bioethics program at Columbia University. So-called “human challenge” or “controlled infection” trials have also been proposed, which would allow researchers to intentionally expose all participants to the virus to assess the experimental vaccine’s effect more quickly. While proponents of controlled infection trials argue that participants …

WHO backs COVID-19 vaccine trials that deliberately infect participants
4 years, 7 months ago

WHO backs COVID-19 vaccine trials that deliberately infect participants

The Hindu  

In new guidelines issued on May 6, the World Health Organization has said that well-designed human challenge studies could not only accelerate coronavirus vaccine development but also make it more likely that the vaccines ultimately deployed will be far more effective. Around 30 Indian attempts at COVID-19 vaccine, says Principal Scientific Adviser In human challenge studies, healthy participants are first …

Vaccine research: Thousands of people want to be exposed to Covid-19 for science
4 years, 7 months ago

Vaccine research: Thousands of people want to be exposed to Covid-19 for science

CNN  

CNN — Abie Rohrig had just turned 18 when he told his mom he would be donating a kidney to save a stranger’s life. Co-authored by Nir Eyal of Rutgers, Marc Lipsitch of Harvard, and Peter Smith of the London School of Hygiene & Tropical Medicine, the piece concluded that while a human challenge study would not be without risks, …

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