Nipah virus: Experimental antiviral drug shows promise
5 years, 9 months ago

Nipah virus: Experimental antiviral drug shows promise

The Hindu  

In a new study published last month, researchers from the National Institutes of Health, U.S., have shown that Remdesivir was able to treat four African green monkeys which were given a lethal dose of Nipah virus. Eight monkeys were inoculated with a lethal dose of Nipah virus Bangladesh strain, and, 24 hours later, four of them were treated intravenously with the drug for 12 consecutive days. Dr. de Wit explains, “We know from patients with Nipah virus that they also often develop this disease of the brain when they are infected. Because the genome is an essential part of the virus, the virus cannot replicate itself very well in the presence of the drug, and there is less damage to organs and thus less severe disease.” “Right now, there are two promising antiviral treatments against Nipah virus that could be used in humans soon. These two treatments could thus be tested in Nipah virus patients in the context of a clinical trial,” explains Dr de Wit.

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History of this topic

Ebola could be cured with a pill, an experiment on monkeys shows
2 weeks ago

Ebola could be cured with a pill, an experiment on monkeys shows

India Today  

Scientists are trying to develop a more practical and affordable treatment for Ebola. "We're really trying to come up with something that was more practical, easier to use, that could be used to help prevent, control, and contain outbreaks," Thomas Geisbert, a virologist at The University of Texas Medical Branch at Galveston, who led the new study, published in Science …

Ebola-infected monkeys cured with a pill, raising hopes for humans: study
2 weeks, 3 days ago

Ebola-infected monkeys cured with a pill, raising hopes for humans: study

Raw Story  

by Issam AHMED Monkeys infected with Ebola can be cured with a pill, according to a new study out Friday that could pave the way for more practical, affordable treatments in humans. "We're really trying to come up with something that was more practical, easier to use, that could be used to help prevent, control, and contain outbreaks," Thomas Geisbert, …

Oxford scientists launch first human vaccine trials for deadly Nipah virus
1 year, 2 months ago

Oxford scientists launch first human vaccine trials for deadly Nipah virus

The Hindu  

Scientists at the University of Oxford in the U.K. have launched first-in-human vaccine trials for the deadly Nipah virus which impacts many Asian countries, including India. "Nipah virus was first identified in 1998, and yet 25 years on the global health community still has no approved vaccines or treatments for this devastating disease," said the trial's Principal Investigator, Brian Angus, …

Human vaccine trials begin in UK for brain swelling Nipah Virus
1 year, 2 months ago

Human vaccine trials begin in UK for brain swelling Nipah Virus

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy The University of Oxford has launched a new clinical trial to …

Human testing of first Nipah virus vaccine begins
1 year, 2 months ago

Human testing of first Nipah virus vaccine begins

India Today  

After successful preclinical trials of a vaccine candidate, called ChAdOx1 NiV, for the brain-swelling Nipah virus, it has entered the human testing phase. Conducted by the University of Oxford with 52 participants, the human trial will assess safety and immune response in individuals aged 18 to 55, a spokesperson for the University's Pandemic Sciences Institute told news agency Reuters. While …

Nipah virus outbreak: Watch out for these 3 risk factors
1 year, 6 months ago

Nipah virus outbreak: Watch out for these 3 risk factors

Hindustan Times  

For the third time in five years, the brain-damaging Nipah virus has surfaced again in the Kozhikode district of Kerala, leading the state health department to declare a health alert after two “unnatural” deaths were reported, followed by four high-risk contact cases with a 9-year-old on ventilator support. Nipah virus outbreak: Watch out for these 3 risk factors In an …

What is Nipah Virus? Symptoms, diagnosis and treatment
1 year, 6 months ago

What is Nipah Virus? Symptoms, diagnosis and treatment

India Today  

Nipah virus has once again been detected in Kerala's Kozhikode district, marking the third occurrence of the virus in the area since 2018. According to the World Health Organisation, Nipah Virus is defined as a zoonotic illness transmitted from animals to humans and can also be spread through contaminated food or direct person-to-person contact. NIPAH VIRUS SIGNS AND SYMPTOMS: Human …

Nipah: Using sticks to find a fatal virus with pandemic potential : Short Wave
2 years, 2 months ago

Nipah: Using sticks to find a fatal virus with pandemic potential : Short Wave

NPR  

Nipah: Using sticks to find a fatal virus with pandemic potential Enlarge this image toggle caption Fatima Tuj Johora for NPR Fatima Tuj Johora for NPR The Nipah virus is on the World Health Organization's short list of diseases that have pandemic potential and therefore post the greatest public health risk. With the Nipah virus came encephalitis — swelling of …

Ebola virus can lurk in the brain and re-emerge years after recovery to cause fatal disease, study finds
3 years, 1 month ago

Ebola virus can lurk in the brain and re-emerge years after recovery to cause fatal disease, study finds

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. “We found that about 20 per cent of monkeys that survived lethal Ebola virus exposure …

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease
3 years, 6 months ago

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease

Firstpost  

Nipah virus or, which was first identified during an outbreak in Kampung Sungai Nipah, Malaysia in 1998, is primarily a zoonotic disease carried by fruit bats of the Pteropodidae family Indian state of Kerala, which has seen a previous outbreak of Nipah virus in 2018 and stray cases going back to as far as 2001, has again reported a case …

Nipah scare: How it spreads, past outbreaks, what to watch out for
5 years, 9 months ago

Nipah scare: How it spreads, past outbreaks, what to watch out for

India TV News  

Nipah scare: How it spreads, past outbreaks, what to watch out for In the absence of a vaccine, the only way to reduce or prevent infection in people is by raising awareness of the risk factors and educating people about the measures they can take to reduce exposure to the Nipah virus. During later outbreaks in Bangladesh and India, the …

Nipah scare: How a Malaysian doctor discovered the deadly virus
5 years, 9 months ago

Nipah scare: How a Malaysian doctor discovered the deadly virus

India TV News  

The Nipah is an RNA virus, which was first discovered as a zoonotic pathogen after a 1999 outbreak involving severe respiratory illness in pigs and encephalitic disease in humans. The nomenclature of Nipah virus, or NiV, originated from Sungai Nipah, a village in the Malaysian Peninsula where pig farmers became ill with encephalitis. In 1999, pig farmers in Malaysia's Sungai …

Nipah kills one more in Kerala's Kozhikode as death toll rises to 17; victim had tested negative for virus on first occasion
6 years, 9 months ago

Nipah kills one more in Kerala's Kozhikode as death toll rises to 17; victim had tested negative for virus on first occasion

Firstpost  

With the death toll rising to 17, one more person who contracted the Nipah Virus infection passed away in Khozikode, Kerala on 1 June. The Nipah virus killed one more person in Kerala’s Kozhikode district on Friday, taking the death toll to 17, reports said. Nipah virus infection is a newly emerging zoonosis that causes severe disease in both animals …

Nipah virus: High hopes on Australian drug
6 years, 10 months ago

Nipah virus: High hopes on Australian drug

Deccan Chronicle  

KOZHIKODE: The death of three more persons in two days has again set the NiV alarm bell ringing. The mortality rate is too high compared to NiV-hit Malaysia, Bangladesh and Siliguri which underlines that the virus here is the most virulent. "The mortality rate in India and Bangladesh for NiV is around 75 per cent, compared to the 40 percent …

Nipah virus: India seeks Austraila's help as death toll reaches 12, asks for antibody to test 'neutralisation' of virus
6 years, 10 months ago

Nipah virus: India seeks Austraila's help as death toll reaches 12, asks for antibody to test 'neutralisation' of virus

Firstpost  

In the wake of Nipah virus cases in Kerala, the Indian Council for Medical Research has written to the Queensland government in Australia asking it to provide an antibody developed to test if it can “neutralise” the virus in humans. New Delhi: In the wake of Nipah virus cases in Kerala, the Indian Council for Medical Research has written to …

Nipah virus outbreak kills 10 in India
6 years, 10 months ago

Nipah virus outbreak kills 10 in India

Al Jazeera  

No vaccine available for deadly infection carried by fruit bats, as 12 tested positive in southern state of Kerala. A virus carried by fruit bats has killed at least 10 people in India’s southern state of Kerala, health and government officials said. K K Shailaja, Kerala state health minister, said on Tuesday that 10 people died of the virus and …

Nipah kills three; Kerala, Centre take steps to tackle virus
6 years, 10 months ago

Nipah kills three; Kerala, Centre take steps to tackle virus

The Quint  

Kozhikode/New Delhi, May 21 After three lives lost to Nipah virus and eight battling the disease in Kerala's Kozhikode district, both the state and the Central governments on Monday took comprehensive measures to contain the outbreak of the rare virus. To strengthen Kerala government's fight against the virus, the Central government on Monday assured the state of all support and …

Experimental Drug Effective Fighting Ebola During Monkey Trial
9 years, 11 months ago

Experimental Drug Effective Fighting Ebola During Monkey Trial

Slate  

While the Ebola epidemic in West Africa and beyond has begun to wane, the race to find a drug to help fight, or prevent, another outbreak continues. On Wednesday, a new study, while far from being conclusive, gave reason for optimism, as an experimental drug saved the lives of monkeys infected with the same strain of the virus that has …

Experimental Drug Saves Monkeys Stricken With Ebola
10 years, 7 months ago

Experimental Drug Saves Monkeys Stricken With Ebola

NPR  

Experimental Drug Saves Monkeys Stricken With Ebola Enlarge this image toggle caption Public Health Agency of Canada/Nature Public Health Agency of Canada/Nature Scientists are reporting strong evidence that the experimental Ebola drug ZMapp may be effective for treating victims of the devastating disease. Sponsor Message The development of ZMapp and its success in treating monkeys at an advanced stage of …

NIH to launch Ebola vaccine trials in humans
10 years, 7 months ago

NIH to launch Ebola vaccine trials in humans

LA Times  

The National Institutes of Health has announced the first clinical trial of a vaccine to protect healthy people from infection by the Ebola virus, which is responsible for an estimated 1,550 deaths throughout West Africa. NIH director Francis Collins on Thursday called the human safety trials, which are to start next week in Bethesda, Md., the latest in a series …

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