Could mosquitoes deliver vaccines against malaria?
2 days, 17 hours ago

Could mosquitoes deliver vaccines against malaria?

Al Jazeera  

Scientists have engineered the pests to provide enhanced immunity to the disease they transmit, according to a new study. Their scientists say they have successfully engineered mosquitoes to deliver vaccines that could potentially provide significantly enhanced immunity against malaria. In the clinical trial, the research team used mosquitoes carrying the modified parasite to deliver the vaccine via bites, mirroring the natural transmission of malaria. The first trial tested an injectable malaria vaccine derived from a genetically modified parasite known as PfSPZ GA1. This was the first significant clinical trial using mosquitoes as a direct vaccine delivery system with genetically modified parasites.

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History of this topic

Fighting mosquito menace with repellents, vaccines
4 months, 2 weeks ago

Fighting mosquito menace with repellents, vaccines

The Hindu  

Since 2007, WHO has called April 15 World Malaria Day to highlight the need for continued investment and sustained political commitment to malaria prevention and control. In 1902, Sir Ronald Ross received the Nobel Prize in Physiology/Medicine for having shown how malaria was transmitted by the bite of Anopheles mosquitoes infecting a human patient in Hyderabad suffering from malaria. The …

‘New era’ in malaria control begins with vaccination campaign for children in Ivory Coast
5 months, 1 week ago

‘New era’ in malaria control begins with vaccination campaign for children in Ivory Coast

The Independent  

For free real time breaking news alerts sent straight to your inbox sign up to our breaking news emails Sign up to our free breaking news emails Sign up to our free breaking news emails SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy The first affordable malaria vaccine …

New malaria vaccine delivered for the first time
6 months, 4 weeks ago

New malaria vaccine delivered for the first time

NPR  

New malaria vaccine delivered for the first time toggle caption Yasuyoshi Chiba/AFP via Getty Images The Central African Republic is the first country to receive thousands of doses of a new malaria vaccine first recommended by the World Health Organization last October. “Now our priority is for the vaccines to reach every child at risk.” Sponsor Message "As a malaria …

Two new malaria vaccines are being rolled out across Africa — how they work and what they promise
7 months, 4 weeks ago

Two new malaria vaccines are being rolled out across Africa — how they work and what they promise

The Hindu  

Malaria incidents are on the rise. Among children aged 5 and 17 months who received 4 doses of RTS,S, the vaccine prevented about 30% of them from developing severe malaria. Since 2019 more than 2 million children in Ghana, Kenya and Malawi have been vaccinated with the RTS,S malaria vaccine. The world’s largest vaccine manufacturer, the Serum Institute of India, …

Could new vaccines end malaria in Africa?
10 months, 1 week ago

Could new vaccines end malaria in Africa?

Al Jazeera  

A decades-long pursuit to disarm mosquitoes has produced new vaccines. In trials carried out between 2009 and 2011 across seven African countries, the RTS,S vaccine prevented infants from developing malaria for at least three years after the first vaccination. It is the number two cause of toddler deaths in Africa after respiratory illnesses – nearly half a million children die …

A Bill Gates-tied mosquito project is not responsible for recent US malaria cases
54 years, 11 months ago

A Bill Gates-tied mosquito project is not responsible for recent US malaria cases

Associated Press  

CLAIM: Rare malaria cases reported in Florida and Texas recently were caused by a disease-control initiative backed by Bill Gates that involved releasing genetically modified mosquitoes in the U.S. AP’S ASSESSMENT: False. One tweet reads: “Malaria has been detected in Florida and Texas, CONVENIENTLY two states where Bill Gates was experimenting with GMO mosquitoes.” “JOIN THE DOTS - Bill Gates …

Promising new malaria vaccine for kids approved in Ghana
1 year, 8 months ago

Promising new malaria vaccine for kids approved in Ghana

The Independent  

For free real time breaking news alerts sent straight to your inbox sign up to our breaking news emails Sign up to our free breaking news emails Please enter a valid email address Please enter a valid email address SIGN UP I would like to be emailed about offers, events and updates from The Independent. Please try again later {{ …

SCIENCE NOTEBOOK | Finally! A safe and effective vaccine against malaria
1 year, 10 months ago

SCIENCE NOTEBOOK | Finally! A safe and effective vaccine against malaria

The Hindu  

Published : Jan 26, 2023 10:25 IST FOR decades scientists had tried different approaches to develop an effective malaria vaccine without much success. Researchers at the Center for Vaccine Development and Global Health of the University of Maryland School of Medicine recently demonstrated that a three-dose regimen of a vaccine called Plasmodium falciparum sporozoite was safe and efficacious when tested …

Antibody treatment tested as a new tool against malaria: Research
2 years, 1 month ago

Antibody treatment tested as a new tool against malaria: Research

Hindustan Times  

Research in Africa found a one-time dose of an experimental drug protected adults against malaria for at least six months, the latest approach in the fight against the mosquito-borne disease. Malaria killed more than 620,000 people in 2020 and sickened 241 million, mainly children under 5 in Africa. The new study tested a very different approach — giving people a …

Antibody treatment tested as new tool against malaria
2 years, 1 month ago

Antibody treatment tested as new tool against malaria

The Hindu  

Research in Africa found a one-time dose of an experimental drug protected adults against malaria for at least six months, the latest approach in the fight against the mosquito-borne disease. The new study tested a very different approach — giving people a big dose of lab-made malaria-fighting antibodies instead of depending on the immune system to make enough of those …

Antibody treatment tested as new tool against malaria
2 years, 1 month ago

Antibody treatment tested as new tool against malaria

LA Times  

Research in Africa found a one-time dose of an experimental drug protected adults against malaria for at least six months, the latest approach in the fight against the mosquito-borne disease. The new study tested a very different approach — giving people a big dose of lab-made malaria-fighting antibodies instead of depending on the immune system to make enough of the …

Explained: How scientists engineered mosquitoes that cannot spread malaria – Firstpost
2 years, 2 months ago

Explained: How scientists engineered mosquitoes that cannot spread malaria – Firstpost

Firstpost  

The genetically modified mosquitos have the ability to slow the growth of malaria-causing parasites in their gut, an innovation that can help prevent transmission of the disease to humans The world of science is reaching new heights. Genetically modified mosquitoes have the ability to slow the growth of malaria-causing parasites in their gut, an innovation that can help prevent transmission …

Scientists engineer mosquitoes that can't spread malaria
2 years, 3 months ago

Scientists engineer mosquitoes that can't spread malaria

The Hindu  

Scientists have genetically modified mosquitoes with the ability to slow the growth of malaria-causing parasites in their gut, an advance that can help prevent transmission of the disease to humans. "Delaying the parasite's growth in the mosquito has opened many more opportunities to block malaria transmission from mosquitoes to humans," said study co-first author, Astrid Hoermann. "Gene drive is one …

Radboud University researchers may have a vaccine that fights the spread of malaria
2 years, 4 months ago

Radboud University researchers may have a vaccine that fights the spread of malaria

NL Times  

Researchers at the Radboud University Medical Center in Nijmegen think they have developed a vaccine that combats the spread of malaria. If an Anopheles mosquito bites a person who has taken the vaccine, and draws a blood meal from them, the malaria parasites in that mosquito are rendered harmless, according to clinical research. A single injection would be enough to …

Malaria Breakthrough! Know symptoms, treatment, prevention and control of mosquito caused disease
2 years, 9 months ago

Malaria Breakthrough! Know symptoms, treatment, prevention and control of mosquito caused disease

India TV News  

Summers are back and so are the mosquitoes and Malaria! Infection with malaria parasites may result in a wide variety of symptoms, ranging from very mild symptoms to severe disease and sometimes, even death. Symptoms of Malaria Shivering and chills High fever Headache Nausea and vomiting Sweating and tiredness Abdominal pain Muscle pain Body aches Weakness In the case of …

Fighting mosquito-borne diseases: work in progress
3 years, 1 month ago

Fighting mosquito-borne diseases: work in progress

The Hindu  

Mosquito-borne diseases have been a scourge for thousands of years, with huge armies defeated, and economies shattered. We were therefore relieved to read reports announcing an effective malaria vaccine, following clinical trials in Burkina Faso conducted by the University of Oxford, the Serum Institute of India and others. A vaccine against dengue, DENGVAXIA, from Sanofi Pasteur, is approved in several …

Africa welcomes new malaria vaccine as a ‘game-changer’
3 years, 2 months ago

Africa welcomes new malaria vaccine as a ‘game-changer’

Associated Press  

LAGOS, Nigeria — African health officials are optimistic that the world’s first malaria vaccine endorsed by the World Health Organization will “dramatically change” the way the continent of 1.3 billion people fights the disease. The Africa CDC director also congratulated the three African countries that participated in the clinical trials for the malaria vaccine, which he said shows “African leadership …

UN endorses world’s 1st malaria vaccine as ‘historic moment’
3 years, 2 months ago

UN endorses world’s 1st malaria vaccine as ‘historic moment’

Associated Press  

LONDON — The World Health Organization on Wednesday endorsed the world’s first malaria vaccine and said it should be given to children across Africa in the hope that it will spur stalled efforts to curb the spread of the parasitic disease. “So obviously if they’ve been vaccinated, they will still be protected.” In recent years, little significant progress has been …

African children to be vaccinated against malaria after WHO issues historic approval
3 years, 2 months ago

African children to be vaccinated against malaria after WHO issues historic approval

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. The long-awaited malaria vaccine for children is a breakthrough for science, child health and malaria …

World Health Organization recommends first anti-malarial vaccine
3 years, 2 months ago

World Health Organization recommends first anti-malarial vaccine

The Hindu  

In a historic move, the World Health Organization on Wednesday endorsed the first anti-malarial vaccine, as mankind enters a key turning point in a battle waged relentlessly over decades between man and mosquito, the vector. The long-awaited malaria vaccine for children is a breakthrough for science, child health and malaria control… Using this vaccine on top of existing tools to …

Question Corner: Can some mosquitoes cause more malaria transmission?
3 years, 11 months ago

Question Corner: Can some mosquitoes cause more malaria transmission?

The Hindu  

According to the World Health Organization, in 2019, there were an estimated 229 million cases of malaria worldwide and the number of malaria deaths stood at 4,09,000. A new study has shown that if a mosquito has multiple bouts of blood meal, it can shorten the incubation period of the parasites and increase the malaria transmission potential. It also makes …

Scientists Map Out Immune Cells in Mosquitoes to Find Out How They Fight off Malaria
4 years, 3 months ago

Scientists Map Out Immune Cells in Mosquitoes to Find Out How They Fight off Malaria

News 18  

Scientists have created the first full map of mosquito immune cells and found a new type of cell that could have a role in how mosquitos are able to fight off malaria. The findings, published in the journal Science, could help scientists uncover new ways of preventing mosquitos from spreading the malaria parasite to people and break the chain of …

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