One shot of vaccine may be enough for COVID-19 survivors, studies suggest
LA TimesFor people who have bared their arms for a two-dose COVID-19 vaccine, the message from public health officials has been clear: Get the second shot if you want full protection. “This has been rumored for a long time, that people with preexisting disease only need a single dose to get really long-lasting immunity,” said Dr. George Rutherford, an infectious disease epidemiologist at UC San Francisco. A preliminary version of those findings prompted Dr. Francis Collins, director of the National Institutes of Health, to observe that “the results raise the possibility that one dose might be enough for someone who’s been infected with SARS-CoV-2 and already generated antibodies against the virus.” However, he added in a blog post, “much more research is needed — and I am definitely not suggesting a change in the current recommendations right now.” The New York scientists also found that people who had previously been infected tended to have more symptoms after their first shot compared with their never-infected peers. “It will also be up to the expert advisors at FDA and Centers for Disease Control and Prevention to decide.” Rutherford said it’s possible such a move might be coming, but that the CDC “has got a lot on its plate.” Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security, said that while the evidence is growing, the CDC “is very cautious” and may be waiting for more research before supporting the change. “If you can spare all those people a second dose, that’s more doses for the rest of the world and also a quicker rollout of first doses in this country,” Adalja said.