Using the body’s own defences to fight cancer: new research offers a clue from COVID-19
The HinduCancer, often called the “emperor of all maladies,” remains a formidable adversary despite decades of scientific progress. Cancer cells often reprogramme the body’s immune system to protect themselves from detection and destruction, much like a thief bribing a security guard to look the other way. Unlike regular monocytes, I-NCMs possess a unique receptor, CCR2, which acts like a specialised antenna to detect signals emitted by certain types of cancer cells or inflamed tissues. Natural killer cells are a vital component of the immune system, directly targeting and eliminating abnormal-appearing cells, such as cancer cells or virus-infected cells. The Northwestern University study highlights the potential of using I-NCMs in treating cancer metastasis, independent of adaptive components of the immune system like T cells and B cells.