Plasma therapy not effective, likely to be dropped from clinical management guidelines on Covid-19
3 years, 7 months ago

Plasma therapy not effective, likely to be dropped from clinical management guidelines on Covid-19

India Today  

Plasma therapy on Covid-19 patients has not been found effective in reducing the progression to severe disease or death and is likely to be dropped from the clinical management guidelines, sources said. In the letter, which was also marked to ICMR chief Balram Bhargava and AIIMS Director Randeep Guleria, public health professionals alleged that the current guidelines on plasma therapy are not based on existing evidence and pointed out some very early evidence that indicates a possible association between emergence of variants with “lower susceptibility to neutralising antibodies in immunosuppressed" people given plasma therapy. "We are writing to you as concerned clinicians, public health professionals and scientists from India about the irrational and non-scientific use of convalescent plasma for Covid-19 in the country. The health professionals added that the PlasmAr trial in Argentina concluded that there is no significant difference in “clinical status or overall mortality between patients treated with convalescent plasma and those who received placebo”.

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