Scientists derive a way to synthesise nano-particles using eggshells for drug delivery

New studies suggest that nanoparticles in eggshells have better physical and biological properties than synthetically derived ones. Researchers feel eggshell-derived nanoparticles may be suitable for use in humans as they have tested biocompatibility of calcium phosphate cement made from eggshells as dental implants in preliminary studies in humans. “Apart from their ability to deliver the antibiotic, eggshell derived apatite nanoparticles also showed higher amount of bovine serum albumin protein delivery, which means they may be employed for delivering growth factors for bone regeneration”, Prof. Sampath Kumar, who led the team, told India Science Wire. In addition to drug delivery, the presence of ions like strontium, magnesium, fluoride and sodium in small amounts in these nanoparticles makes them potentially useful as graft materials for bone regeneration. “Preliminary clinical studies with six patients have indicated clinical efficacy of eggshell derived cements in treating bone defects, demonstrating complete resorption with new bone formation”, Kumar said.