
Scientists unlock how Zika virus hijacks our skin to be a "mosquito magnet"
SalonZika, a mosquito-borne virus first identified in 1947 in a Rhesus macaque monkey, continues to perplex scientists in many ways nearly 80 years later. A new study published in Communications Biology shows that Zika causes metabolic changes in human skin that transform it from a barrier to a magnet for mosquitoes, furthering the scientific community’s understanding of the virus. “Our findings show that Zika virus isn’t just passively transmitted, but it actively manipulates human biology to ensure its survival,” Dr. Noushin Emami, co-lead author of the paper, said in a media statement. “As Zika cases rise and Aedes mosquitoes expand their range, understanding the mechanisms by which they gain a transmission advantage could unlock new strategies for combating arboviruses,” Emami said. “We showed that ANKLE2 is really important for accelerating Zika virus replication in human cells, in a broad range of human cells, so liver neurons and even placental cells, which are all tissues that Zika virus can infect,” Shah said.
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