‘Breakthrough’: WHO hails steroid treatment for coronavirus
4 years, 6 months ago

‘Breakthrough’: WHO hails steroid treatment for coronavirus

Al Jazeera  

UK study shows dexamethasone reduces deaths by about 30 percent in critical COVID patients, some US doctors sceptical. The World Health Organization plans to update its guidelines on treating people stricken with coronavirus to reflect results of a clinical trial that showed a cheap, common steroid could help save critically ill patients. ‘Best piece of news’ Britain’s health minister on Wednesday hailed the use of the steroid for treating coronavirus patients as the “best news” so far during the outbreak. “I just wait to see the real data, see if it’s peer-reviewed and gets published.” University of Washington professor of medicine Dr Mark Wurfel urged the researchers to release the data before official publication. “That would be very, very helpful in terms of helping us align our patient populations with theirs and decide whether it’s appropriate to apply this therapy to our patients,” said Wurfel.

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History of this topic

High-dose Covid treatment less effective in India than Europe: Lancet study
1 year, 1 month ago

High-dose Covid treatment less effective in India than Europe: Lancet study

Hindustan Times  

A higher dose of the steroid drug, dexamethasone, may have less beneficial effects for COVID-19 patients in India as compared with those in Europe, according to a study published in The Lancet Regional Health - Southeast Asia journal. The study looked at how well a strong dose of dexamethasone worked for COVID-19 patients. The team, including researchers from Copenhagen University …

Mumbai: Doctors flag indiscriminate use of steroids, antibiotics in Covid-19 treatment
3 years, 8 months ago

Mumbai: Doctors flag indiscriminate use of steroids, antibiotics in Covid-19 treatment

Hindustan Times  

A 43-year-old man from Andheri was prescribed a cocktail of antibiotics, antiviral, and steroids on his first consultation with a local physician when he developed symptoms and was suspected of Covid-19. Indiscriminate use “Starting patients on steroids early is harmful for them,” said infectious disease expert Dr Tanu Singhal from Kokilaben Dhirubhai Ambani Hospital where the 43-year-old man and the …

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists
4 years, 1 month ago

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists

News 18  

Most adults with moderate-to-severe COVID-19 have a suppressed immune response against the novel coronavirus rather than life-threatening hyper-inflammation, according to a study which suggests steroids such as dexamethasone should be reserved for the sickest patients. According to the research, published in the journal Science Advances, fewer than 5 per cent of the COVID-19 patients, including some of the sickest individuals, …

Covid-19 deaths aren’t rising as fast in Europe and US, despite soaring new infections. That doesn’t mean the virus is less deadly
4 years, 2 months ago

Covid-19 deaths aren’t rising as fast in Europe and US, despite soaring new infections. That doesn’t mean the virus is less deadly

CNN  

CNN — Europe is drowning in the second wave of the coronavirus epidemic. “Our current estimate is that the infection fatality rate is going up a little bit, but it hasn’t come up to anywhere near where we were and that’s unlikely to change dramatically unless we see a really surprising increase in the numbers of deaths.” Oke has been …

Treat coronavirus early to save patients’ lives, SARS veteran urges
4 years, 2 months ago

Treat coronavirus early to save patients’ lives, SARS veteran urges

Live Mint  

Hong Kong’s top pandemic doctor sees a way out of intensive care for thousands of Covid-19 patients: keeping them from entering in the first place. Yuen said he wasn’t surprised by the results of the WHO’s study because the drugs weren’t administered soon after patients became ill. “No antiviral will work if given late,” he said. “We need early cocktail …

WHO: Study finds four drugs that have little to no effect on coronavirus, including remdesivir
4 years, 2 months ago

WHO: Study finds four drugs that have little to no effect on coronavirus, including remdesivir

India Today  

The World Health Organisation announced Friday the long-awaited results of its six-month “Solidarity Therapeutics Trial” that endeavored to see if existing drugs might have an effect on the coronavirus. What the study found The study, which was not peer-reviewed, found that four treatments tested - remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon - had “ little or no effect" on whether or …

Steroids to Covid-19 Patients Who Don't Require Oxygen May Increase Severity: PGIMER
4 years, 3 months ago

Steroids to Covid-19 Patients Who Don't Require Oxygen May Increase Severity: PGIMER

News 18  

The Post Graduate Institute of Medical Education and Research, Chandigarh has noted that the seriousness of the COVID patients coming to hospitals has surged recently. One of the reasons observed behind the surge is the indiscriminate use of steroids in the cases of COVID-19 at an initial stage, the institute stated on Thursday. “It has been observed by experts here …

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients
4 years, 3 months ago

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients

NPR  

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients Enlarge this image toggle caption Nati Harnik/AP Nati Harnik/AP Editor's note: Since we published this story, Trump's physician said that the president has completed his treatment for COVID-19. The steroid, dexamethasone, is now part of the "standard of care" for COVID-19, said Dr. Celine Gounder, assistant professor …

Dexamethasone: What is the new life-saving coronavirus drug?
4 years, 3 months ago

Dexamethasone: What is the new life-saving coronavirus drug?

The Independent  

Sign up to our free Living Well email for advice on living a happier, healthier and longer life Live your life healthier and happier with our free weekly Living Well newsletter Live your life healthier and happier with our free weekly Living Well newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. …

Medical Experts Raise Questions About Severity Of Trump's COVID-19 Infection
4 years, 3 months ago

Medical Experts Raise Questions About Severity Of Trump's COVID-19 Infection

Huff Post  

LOADING ERROR LOADING - Doctors not involved in treating President Donald Trump for COVID-19 said the fact that he has been started on dexamethasone - a generic steroid widely used in other diseases to reduce inflammation - is evidence his case is severe. “What I heard in the news conference description suggested the President has more severe illness than the …

Steroids can be lifesaving for a few seriously ill COVID-19 patients, new studies suggests
4 years, 4 months ago

Steroids can be lifesaving for a few seriously ill COVID-19 patients, new studies suggests

Firstpost  

WHO warned against indiscriminate use of steroids, emphasizing that patients who are not severely ill are unlikely to benefit and may suffer side effects. International clinical trials published Wednesday confirm the hope that cheap, widely available steroid drugs can help seriously ill patients survive COVID-19, the illness caused by the coronavirus. Based on the new evidence, the World Health Organization …

Steroids Confirmed To Help Severely Ill Coronavirus Patients
4 years, 4 months ago

Steroids Confirmed To Help Severely Ill Coronavirus Patients

News 18  

New studies confirm that multiple types of steroids improve survival for severely ill COVID-19 patients, cementing the cheap drugs as a standard of care. An analysis of pooled results from seven studies, led by the World Health Organization and published Wednesday by the Journal of the American Medical Association, found that steroids reduced the risk of death in the first …

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients
4 years, 4 months ago

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients

NPR  

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients Enlarge this image toggle caption Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Three new studies strongly support using inexpensive and widely available drugs to treat people who are seriously ill with COVID-19. Sponsor Message "Giving steroids to COVID-19 could have been …

Coronavirus: Hydroxychloroquine trialled over better treatments
4 years, 6 months ago

Coronavirus: Hydroxychloroquine trialled over better treatments

Daily Mail  

More than 1,200 studies looking at treatment and prevention of coronavirus are often too small to provide conclusive results and are focusing too much on one potential therapy, a new analysis reveals. Commissioned by STAT News, the report found that one in every six clinical trials studied the anti-malaria drugs hydroxychloroquine or chloroquine despite thin evidence that either are effective …

Centre includes includes dexamethasone drug in COVID-19 treatment protocol for moderate to severe cases
4 years, 6 months ago

Centre includes includes dexamethasone drug in COVID-19 treatment protocol for moderate to severe cases

Firstpost  

The updated protocol includes the advice to use dexamethasone as an alternative choice to methylprednisolone for managing moderate to severe cases of COVID-19. New Delhi: An inexpensive, widely used steroid dexamethasone was included in the treatment protocols for COVID-19 patients in moderate to severe stages of illness among other therapeutic measures by the Union health ministry on Saturday. According to …

Health ministry approves use of dexamethasone for coronavirus treatment
4 years, 6 months ago

Health ministry approves use of dexamethasone for coronavirus treatment

India Today  

The Union Ministry of Health and Family Welfare on Saturday issued an updated clinical management protocol for managing the novel coronavirus cases. Keeping pace with evolving knowledge about Covid-19, especially in terms of effective drugs, the change by the health ministry was made after considering the latest available evidence and expert consultation. The guidance document has also been made available …

Dutch pharma sees dexametasone demand rising after Covid-19 treatment study
4 years, 6 months ago

Dutch pharma sees dexametasone demand rising after Covid-19 treatment study

NL Times  

A spike in demand for anti-inflammatory steroid dexamethasone could send prices of the drug higher after researchers at Oxford University showed it could provide relief to some Covid-19 patients. A drug price comparison tool provided by the Dutch government shows that dexamethasone costs about 11 cents per day for tablets, while in liquid form for use intravenously, prices start at …

Doctor’s Note: Can dexamethasone treat COVID-19?
4 years, 6 months ago

Doctor’s Note: Can dexamethasone treat COVID-19?

Al Jazeera  

With the coronavirus pandemic tightening its grip on the world and economies grinding to a standstill, the race is on to find a vaccine. In March, the World Health Organization announced a large global trial, called Solidarity, to find out whether any existing drugs can treat infections caused by COVID-19. What we do know about patients that suffer the worst …

Dexamethasone: US doctors cast doubt on UK’s coronavirus ‘breakthrough’
4 years, 6 months ago

Dexamethasone: US doctors cast doubt on UK’s coronavirus ‘breakthrough’

The Independent  

Sign up to our free weekly IndyTech newsletter delivered straight to your inbox Sign up to our free IndyTech newsletter Sign up to our free IndyTech newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. Professor Peter Horby of Oxford University said the Recovery Trial project findings show the drug would, on …

Dexamethasone | WHO says more understanding needed on steroid
4 years, 6 months ago

Dexamethasone | WHO says more understanding needed on steroid

The Hindu  

The emergencies chief of the World Health Organization welcomed the news this week that dexamethasone, a cheap steroid, was shown in a British trial to reduce deaths among patients critically ill with the coronavirus, but said it was too soon to change how patients are treated. “It’s one of the breakthroughs we’re going to need to effectively deal with COVID-19, …

WHO moves to update Covid-19 guidance after ’major breakthrough’ in drug study
4 years, 6 months ago

WHO moves to update Covid-19 guidance after ’major breakthrough’ in drug study

Live Mint  

The World Health Organization said it was moving to update its guidelines on treating people stricken with Covid-19 to reflect results of a clinical trial that showed a cheap, common steroid can help save critically ill patients. Trial results announced on Tuesday by researchers in Britain showed dexamethasone, used since the 1960s to reduce inflammation in diseases such as arthritis, …

Steroid dexamethasone approved for use in COVID-19 treatment in U.K.
4 years, 6 months ago

Steroid dexamethasone approved for use in COVID-19 treatment in U.K.

The Hindu  

The U.K. government on Wednesday authorised the State-funded National Health Service to use steroid, the world’s first coronavirus treatment proven to reduce the risk of death among severely ill patients. The Department of Health said the cheap and widely available anti-inflammatory steroid has been immediately approved to treat all hospitalised COVID-19 patients requiring oxygen, including those on ventilators, after an …

Dexamethasone shows promise in treatment of severely ill COVID-19 patients: All you need to know about the steroid drug
4 years, 6 months ago

Dexamethasone shows promise in treatment of severely ill COVID-19 patients: All you need to know about the steroid drug

Firstpost  

The Oxford University announced that dexamethasone, a common steroid drug, has shown promise in the treatment of severely ill COVID-19 patients by improving their survival rate by at least 20 percent The Oxford University announced that dexamethasone, a common steroid drug, has shown promise in the treatment of severely ill COVID-19 patients by improving their survival rate by at least …

COVID-19 'RECOVERY' Trial: Dexamethasone found life-saving in seriously-ill patients in preliminary tests
4 years, 6 months ago

COVID-19 'RECOVERY' Trial: Dexamethasone found life-saving in seriously-ill patients in preliminary tests

Firstpost  

As part of the Recovery trial, a range of potential treatments is being tested in consenting COVID-19 patients admitted to NHS hospitals in the UK. “This is the most important trial result for COVID-19 so far,” Chris Whitty, England’s Chief Medical Officer, said on Twitter about the findings of the UK-led clinical trial known as ‘RECOVERY’. “This is the first …

Dexamethasone: A magical Corona drug that you should take only on prescription
4 years, 6 months ago

Dexamethasone: A magical Corona drug that you should take only on prescription

India Today  

Before a Covid-19 specific drug formula is found, a magical cure has been found to treat novel coronavirus infection. The researchers administered dexamethasone to around 2,100 patients in hospitals and compared their recovery with another set of over 4,300 patients who were not given the drug. They found dexamethasone to be a life-saving drug for Covid-19 patients. The researchers at …

How dexamethasone might lead researchers to better COVID-19 treatments
4 years, 6 months ago

How dexamethasone might lead researchers to better COVID-19 treatments

LA Times  

The steroid drug dexamethasone can be lifesaving for patients with severe COVID-19. In preliminary clinical trial results announced Tuesday, patients on mechanical ventilators who were treated with the steroid dexamethasone were 35% less likely to die of COVID-19 than their counterparts who got standard care without the drug. A medication like dexamethasone is a “blunt instrument,” said Dr. Steven J. …

Dexamethasone could be the miracle drug to reduce COVID-19 mortality rate
4 years, 6 months ago

Dexamethasone could be the miracle drug to reduce COVID-19 mortality rate

Deccan Chronicle  

New Delhi: For countries battling high mortality rate due to the coronavirus pandemic, steroid Dexamethasone can be a boon, as researchers in England have claimed that it can reduce COVID-19 deaths by one-third in severely ill hospitalised patients. The chief investigators of the randomised evaluation of COVID -19 therapy trial said low-cost Dexamethasone reduces death by up to one-third in …

Dexamethasone: UK approves NHS use of life-saving drug for severely ill coronavirus patients
4 years, 6 months ago

Dexamethasone: UK approves NHS use of life-saving drug for severely ill coronavirus patients

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy The government has authorised the use of a drug which has …

Indian doctors express cautious endorsement for dexamethasone for COVID-19
4 years, 6 months ago

Indian doctors express cautious endorsement for dexamethasone for COVID-19

The Hindu  

Indian doctors have said the reported success of dexamethasone — an inexpensive steroid that retails for less than ₹10 for 10 ml and is made by several Indian manufacturers — at curing COVID-19 patients on ventilators is good news for India. Scientists administering the WHO-administered RECOVERY trial — the largest global clinical trial — that is checking the ability of …

Major COVID-19 breakthrough: A cheap Dexamethasone drug 'reduces risk of death in ventilated patients'
4 years, 6 months ago

Major COVID-19 breakthrough: A cheap Dexamethasone drug 'reduces risk of death in ventilated patients'

India TV News  

A cheap, widely available steroid called dexamethasone reduced deaths by up to one third in severely ill hospitalized patients. “Dexamethasone must now be rolled out and accessed by thousands of critically ill patients around the world,” said Cammack, who had no role in the study. Researchers estimated that the drug would prevent one death for every eight patients treated while …

Coronavirus | Dexamethasone reduces deaths from COVID-19, say researchers in U.K.
4 years, 6 months ago

Coronavirus | Dexamethasone reduces deaths from COVID-19, say researchers in U.K.

The Hindu  

Researchers in the U.K. say they have the first evidence that a drug can improve COVID-19 survival: A steroid called dexamethasone reduced deaths by up to one third in severely ill hospitalised patients. The study is a large, strict test that randomly assigned 2,104 patients to get the drug and compared them with 4,321 patients getting only usual care. “The …

Coronavirus: £5 steroid dexamethasone 'reduces risk of death'
4 years, 6 months ago

Coronavirus: £5 steroid dexamethasone 'reduces risk of death'

Daily Mail  

Prime Minister Boris Johnson today hailed the 'biggest breakthrough yet' in the UK's coronavirus fight as officials announced they have found a drug that could save up to a third of critically-ill Covid-19 patients. In other coronavirus developments in Britain today: Two women travelling to New Zealand to visit a dying parent tested positive for Covid-19, ending the country's 24-day …

Coronavirus pandemic claims a new type of victims: Prestigious medical journals — The Lancet and New England Journal of Medicine
4 years, 6 months ago

Coronavirus pandemic claims a new type of victims: Prestigious medical journals — The Lancet and New England Journal of Medicine

Firstpost  

Journals used to take many months, or a year, to scrutinize and edit a complicated study, now peer review may be condensed to as little as 48 hours. “The problem with trust is that it’s too easy to lose and too hard to get back,” said Dr Jerome Kassirer, former editor-in-chief of the New England Journal of Medicine, which published …

Dexamethasone reduces death risk in severe COVID-19 cases: Trial
4 years, 6 months ago

Dexamethasone reduces death risk in severe COVID-19 cases: Trial

Al Jazeera  

Steroid cuts risk of death by a third for patients on ventilators, by a fifth for those on oxygen, researchers say. “Based on these results, one death would be prevented by treatment of around 8 ventilated patients or around 25 patients requiring oxygen alone,” a University of Oxford statement said. Dexamethasone is inexpensive, on the shelf, and can be used …

Steroid drug: A ‘breakthrough’ in the fight against coronavirus?
4 years, 6 months ago

Steroid drug: A ‘breakthrough’ in the fight against coronavirus?

Al Jazeera  

UK has approved the drug use in the state-run health service and stockpiled 200,000 courses of the treatment. A cheap and widely-used steroid called dexamethasone has become the first drug shown to be able to save lives among COVID-19 patients in what scientists said is a “major breakthrough” in the coronavirus pandemic. “This is a result that shows that if …

Dexamethasone can improve COVID-19 survival, study shows
4 years, 6 months ago

Dexamethasone can improve COVID-19 survival, study shows

LA Times  

In a development that could dramatically shrink the death toll of the COVID-19 pandemic, British researchers have found that a cheap and readily available steroid prevented more than a third of the sickest patients from dying. If people are tempted to use it inappropriately, it “will cause much sicker patients,” said Dr. Steven J. O’Day, director of regional research at …

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients
4 years, 6 months ago

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients

NPR  

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients toggle caption John Minchillo/AP A low-cost anti-inflammatory drug appears to reduce the risk of death in patients with COVID-19. Sponsor Message "Dexamethasone reduced deaths by one-third in ventilated patients," according to a news release from the RECOVERY trial organizers, "and by one fifth in other patients receiving oxygen only." …

Coronavirus | Authors pull controversial Lancet study flagging hydroxychloroquine risks
4 years, 7 months ago

Coronavirus | Authors pull controversial Lancet study flagging hydroxychloroquine risks

The Hindu  

The Lancet on Thursday retracted a study that raised safety fears over the use of a drug favoured by President Donald Trump to treat COVID-19, after the paper's authors said they could no longer vouch for its underlying data. It was soon followed by the withdrawal of another coronavirus paper in the New England Journal of Medicine that was not …

Coronavirus | Hydroxychloroquine clinical trials will resume, says WHO
4 years, 7 months ago

Coronavirus | Hydroxychloroquine clinical trials will resume, says WHO

The Hindu  

The World Health Organisation said on Wednesday that clinical trials of the drug hydroxychloroquine will resume, after having been suspended pending a safety review in the search for coronavirus treatments. Concerns about data British medical journal The Lancet said on Tuesday that it had concerns about data behind an influential article that found that HCQ increased the risk of death …

Coronavirus UK: FTSE drops again as it slumps due to gloomy prospects for new drugs
4 years, 8 months ago

Coronavirus UK: FTSE drops again as it slumps due to gloomy prospects for new drugs

Daily Mail  

Stock markets fell today after a promising drug that experts hoped would become a breakthrough treatment for coronavirus flopped in its first key trial. Gilead also said that trends in the data suggest a potential benefit for remdesivir, 'particularly among patients treated early in disease'. Gilead is testing remdesivir in multiple trials, with results from a study involving 400 patients …

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