Omicron: Vaccines May Partially Work Against New Variant, Ex-ICMR Scientist Dr Gangakhedkar Says
News 18Amid growing concerns over Omicron, former Indian Council of Medical Research scientist Dr Raman Gangakhedkar told News18 that vaccines may provide only partial protection against the new ‘heavily mutated’ variant of SARS-CoV-2. “Everyone must make efforts to protect themselves against the virus and not provide an opportunity for the virus to enter, replicate and thus mutate further inside their body.” Each time the virus reproduces, it involves a risk of producing more faulty copies that have mutations, he said while insisting that “Indians must take both doses of vaccine as an urgency.” A new coronavirus variant — B.1.1.529, officially named Omicron by the World Health Organisation — is known to carry 50 mutations overall, including more than 30 on the spike protein alone. “But here spike proteins are different which may reduce the effectiveness of vaccines and vaccines may provide partial protection.” Changes in Spike Protein May Ease Monitoring While there is a fear related to the changes in spike protein as the mutations are “large in number”, Gangakhedkar, who retired from ICMR last June said “the surveillance benefit is the difference between Omicron and other variants can be spotted from the RT-PCR test itself. Hence only 2 out of three genes will be positive,” he explained while adding that “all the positive samples where only 2 genes are found should be sent for genome sequencing instead of sending all samples.” The new strain has been red-flagged by scientists due to an alarmingly high number of mutations, expecting that the heavy mutations might make the virus more resistant to vaccines, increase transmissibility and lead to more severe symptoms.