Did you get COVID but never feel sick? New study hints at why
1 year, 5 months ago

Did you get COVID but never feel sick? New study hints at why

LA Times  

Commuters with and without face masks walk through Los Angeles Union Station on Dec. 6, 2022. “This is the first time where, in a really rigorous and robust way, anybody has shown that there is a clear, definitive genetic underpinning to asymptomatic disease — not all asymptomatic disease, but some subset of people who stay asymptomatic,” said UC San Francisco neurology professor Jill Hollenbach, a co-author of the study. Significantly, the scientists found that people who had a particular version of a gene — called HLA-B*15:01 — were more than twice as likely to remain asymptomatic compared with those who didn’t, Hollenbach said. And if a person had two copies of the HLA-B*15:01 version of this gene — one from each parent — “they were 8½ times more likely to have remained asymptomatic,” Hollenbach said. “But for whatever reason, the previous immunity that’s mediated by B*15:01 is particularly effective and gives people this chance to become infected with SARS-CoV-2 without having any symptoms at all,” Hollenbach said.

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History of this topic

‘Long colds’ just as common as long Covid, say researchers
1 year, 3 months ago

‘Long colds’ just as common as long Covid, say researchers

The Telegraph  

Experts looked at data from 10,203 people taking part in the Covidence UK study into coronavirus in the population and found 1,343 had suffered a Covid infection and 472 a respiratory infection that tested negative for Covid. “Our findings shine a light not only on the impact of long Covid on people’s lives, but also other respiratory infections,” Giulia Vivaldi, …

Had Covid but never felt sick? Scientists think they've finally cracked the secret of the 'super-dodgers'
1 year, 5 months ago

Had Covid but never felt sick? Scientists think they've finally cracked the secret of the 'super-dodgers'

Daily Mail  

*** Have you still never had Covid? Email [email protected] Scientists think they have finally cracked the secret of why some people who got Covid never became ill. And the answer lies in their genes. Nasim Forooghi, 46, a cardiac research nurse at St Bartholomew's Hospital in Central London, was heavily involved in research tracking Covid among frontline staff – a …

You know those folks who had COVID but no symptoms? A new study offers an explanation
1 year, 5 months ago

You know those folks who had COVID but no symptoms? A new study offers an explanation

NPR  

You know those folks who had COVID but no symptoms? A new study offers an explanation Enlarge this image toggle caption CNRI / Science Source CNRI / Science Source Do you know someone who tested positive for COVID but never felt a darn thing? Bone marrow donors were key to the study Jill Hollenbach, an immunologist at the University of …

US study finds 1 in 10 get long COVID after omicron, starts identifying key symptoms
1 year, 7 months ago

US study finds 1 in 10 get long COVID after omicron, starts identifying key symptoms

Associated Press  

WASHINGTON — About 10% of people appear to suffer long COVID after an omicron infection, a lower estimate than earlier in the pandemic, according to a study of nearly 10,000 Americans that aims to help unravel the mysterious condition. Early findings from the National Institutes of Health’s study highlight a dozen symptoms that most distinguish long COVID, the catchall term …

Study finds long COVID symptoms 'on par' with influenza in vaccinated population, but infectious diseases expert raises concerns
1 year, 8 months ago

Study finds long COVID symptoms 'on par' with influenza in vaccinated population, but infectious diseases expert raises concerns

ABC  

An infectious diseases physician has urged caution over a Queensland Health study comparing the impacts of COVID-19 and influenza, saying it is "very limited" and there is a danger of "downplaying the ongoing significance of COVID". Key points: At 12 weeks, 21 per cent of people with COVID and 23 per cent of people with influenza reported ongoing symptoms according …

Still never had Covid? Thank your genes: Three in 10 people have a gene that blocks infection
2 years, 2 months ago

Still never had Covid? Thank your genes: Three in 10 people have a gene that blocks infection

Daily Mail  

The gene HLA-DQB1*06 will give people more antibodies after Covid shots People escaping Covid infection might have a special gene to help them Some people might never get Covid thanks to their genes, scientists say. The 'never Covid' group might have a gene called HLA-DQB1*06 which gives them even better protection after Covid shots Lead researcher Dr Alexander Mentzer said: …

Why do some people not catch COVID-19, despite exposure? Scientists are trying to solve the puzzle
2 years, 9 months ago

Why do some people not catch COVID-19, despite exposure? Scientists are trying to solve the puzzle

ABC  

When Vanessa Bryant recently managed to dodge COVID-19 despite the rest of her young family getting infected, she felt fortunate — but not entirely surprised. "When we first started doing PCR testing, it was really done on symptomatic people … so we were obviously missing a lot of those asymptomatic people," Professor Tangye said. "Studies have shown a certain amount …

The genetic variants causing severe COVID-19
2 years, 9 months ago

The genetic variants causing severe COVID-19

The Hindu  

The story so far: Scientists in the United Kingdom as part of a research project, GenOMICC, have identified 16 new genetic variants that make a person more susceptible to a severe COVID-19 infection. A single gene variant, the team found, disrupted a key messenger molecule in immune system signalling — called interferon alpha-10 — that increased a patient’s risk of …

Polish scientists find gene that decides how seriously you suffer from Covid, 27% Indians have it
2 years, 11 months ago

Polish scientists find gene that decides how seriously you suffer from Covid, 27% Indians have it

India Today  

Polish scientists have found a gene that they say more than doubles the risk of becoming severely ill with Covid-19, a discovery they hope could help doctors identify people who are most at risk from the disease. With vaccine hesitancy a major factor behind high coronavirus death rates in central and eastern Europe, researchers hope that identifying those at greatest …

Delta variant major cause for COVID in children during second wave: ICMR study
2 years, 11 months ago

Delta variant major cause for COVID in children during second wave: ICMR study

Deccan Chronicle  

New Delhi: The Delta variant was the major cause of coronavirus infection in children's COVID-19 cases during the second wave in India, according to an Indian Council of Medical Research study. The most common lineages observed were Delta, followed by Kappa, Alpha and B.1.36, seen in 65.82 per cent, 9.96 per cent, 6.83 per cent and 4.68 per cent, respectively …

Posts misrepresent Washington University study on COVID-19 immunity
3 years ago

Posts misrepresent Washington University study on COVID-19 immunity

Associated Press  

CLAIM: Researchers from Washington University School of Medicine in St. Louis released data showing that if you have had COVID-19, even a mild case, you are likely protected from the virus for life. “If you’ve had COVID-19, even a mild case, major congratulations to you as you’ve more than likely got long-term immunity, according to a team of researchers from …

Vaccination after Covid infection gives some people ‘superhuman’ immunity, study finds
3 years, 4 months ago

Vaccination after Covid infection gives some people ‘superhuman’ immunity, study finds

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Those with this type of immunity could even have “some degree of protection against the …

Gene link behind asymptomatic Covid-19 identified
3 years, 7 months ago

Gene link behind asymptomatic Covid-19 identified

India TV News  

A team of scientists has identified a genetic link explaining why some people who catch Covid-19 don't become sick. The team led by Newcastle University in the UK demonstrated that the gene HLA-DRB1*04:01 is found three times as often in people who are asymptomatic, suggesting that people carrying this gene have some level of protection from severe Covid. "This is …

Trinity College research finds why COVID 19 is to hard to treat
3 years, 8 months ago

Trinity College research finds why COVID 19 is to hard to treat

India TV News  

Researchers at the Trinity College Dublin showed that a comprehensive review into what we know about Covid 19 and the way it functions suggests that the virus has a unique infectious profile, which explains why it can be so hard to treat and why some people experience a long struggle with the virus, and even after the virus is technically …

Why easing COVID-19 restrictions too soon could be a boon for coronavirus variants
3 years, 10 months ago

Why easing COVID-19 restrictions too soon could be a boon for coronavirus variants

LA Times  

Pam Nestande shops at Hemline Austin on Wednesday, the day Texas lifted its COVID-19 mask mandate. So while we’re vaccinating people, we want to make sure there’s less and less virus circulating that doesn’t put our vaccine efficacy at risk.” March and April “are critical periods here,” Walensky added. “This finding underscores the need to limit subsequent waves of infection …

Dangerous new coronavirus strains may incubate in COVID-19’s sickest
3 years, 11 months ago

Dangerous new coronavirus strains may incubate in COVID-19’s sickest

LA Times  

A nurse brings medication to a COVID-19 patient in an hospital intensive care unit. Among the sickest of COVID-19 patients, this population of “long haulers” appears to play a key role in incubating new variants of the coronavirus, some of which could change the trajectory of the pandemic. Indeed, situations in which patients can’t clear a viral infection are “the …

Pre-existing antibodies may protect some people against novel coronavirus, says study
4 years, 2 months ago

Pre-existing antibodies may protect some people against novel coronavirus, says study

India TV News  

Scientists have found that some antibodies, created by the immune system during infection with common cold coronaviruses, can also target the COVID-19 causing SARS-CoV-2, and may confer a degree of protection against the new virus. "Our results show that children are much more likely to have these cross-reactive antibodies than adults," said Kevin Ng, lead author of the study from …

People With Previous Infection of 'Common Cold' Coronavirus Likely to Contract Less Severe Covid-19
4 years, 3 months ago

People With Previous Infection of 'Common Cold' Coronavirus Likely to Contract Less Severe Covid-19

News 18  

Being previously infected with coronaviruses that cause the ‘common cold’ may decrease the severity of infections, the virus behind Covid-19, say researchers, including one of Indian-origin. “Our results show that people with evidence of a previous infection from a “common cold” coronavirus have less severe Covid-19 symptoms,” said study author Manish Sagar from Boston University in the US. After adjusting …

Majority of COVID-19 cases developed symptoms, only 20 pc asymptomatic: Study
4 years, 3 months ago

Majority of COVID-19 cases developed symptoms, only 20 pc asymptomatic: Study

India TV News  

Most people who are infected by the SARS-CoV-2 virus, that causes COVID-19, are not asymptomatic throughout the course of infection, a review of studies carried early in the pandemic suggests. Some people with the virus may experience severe infections resulting in viral pneumonia, respiratory distress syndrome, and death, while others remain completely asymptomatic or develop mild, nonspecific symptoms. The researchers …

Scientists document cases of asymptomatic COVID-19 reinfection
4 years, 3 months ago

Scientists document cases of asymptomatic COVID-19 reinfection

The Hindu  

Researchers have reported what may possibly the first instance of people in India being infected twice over by sars-cov2 but remaining asymptomatic. “Our analysis suggests that asymptomatic reinfection may be a potentially under-reported entity,” say the rep where IGIB is involved but we haven't finished the genome sequences are 16. There are several more research studies forthcoming where we have …

August 31 coronavirus news
4 years, 4 months ago

August 31 coronavirus news

CNN  

Many frontline health care workers who care for Covid-19 patients may be infected and not even know it, researchers led by the Centers for Disease Control and Prevention reported Monday. “A high proportion of SARS-CoV-2 infections among healthcare personnel appear to go undetected,” the team at academic medical centers across the country, including the CDC Covid-19 Response Team, wrote in …

There are now three known cases of patients contracting COVID-19 twice
4 years, 4 months ago

There are now three known cases of patients contracting COVID-19 twice

Salon  

There are now three known cases around the world of patients who had been previously afflicted by COVID-19 who contracted the virus a second time, months after clearing the first infection. "Our understanding of the interaction of the SARS-CoV-2 virus with the human immune system is at a very early stage," Medford explained by email. Medford said the next step …

Singapore Scientists Find Coronavirus Variant Which Causes Milder Infections, Elicits Robust Immune Response
4 years, 4 months ago

Singapore Scientists Find Coronavirus Variant Which Causes Milder Infections, Elicits Robust Immune Response

News 18  

Researchers in Singapore have discovered a new variant of the COVID-19 coronavirus that causes milder infections, according to a study published in The Lancet medical journal this week. The study showed that COVID-19 patients infected with a new variant of SARS-CoV-2 had better clinical outcomes, including a lower proportion developing low blood oxygen or requiring intensive care. The study also …

Asymptomatic people with COVID-19 are just as contagious as those showing symptoms, key study finds
4 years, 5 months ago

Asymptomatic people with COVID-19 are just as contagious as those showing symptoms, key study finds

Firstpost  

The findings have implications in many countries including India, where new reported cases are fluctuating, but overall, still on the rise. In a new study of over 300 COVID-19 patients in South Korea, researchers have found that those with and without symptoms are equally likely to transmit the SARS-CoV-2 coronavirus. The study offers evidence in the consequential debate about how …

Coronavirus | What role do people without symptoms play in spreading COVID-19?
4 years, 6 months ago

Coronavirus | What role do people without symptoms play in spreading COVID-19?

The Hindu  

The story so far: On June 8, the technical lead of the World Health Organisation, on the COVID-19 pandemic, said transmission by people without symptoms is “very rare”. On Monday, June 8, at a virtual press conference, Dr. Maria van Kerkhove, WHO’s technical lead on the COVID-19 pandemic, said in response to a question by a journalist, that current evidence …

Up to 45 per cent of coronavirus infections may be asymptomatic: Study
4 years, 6 months ago

Up to 45 per cent of coronavirus infections may be asymptomatic: Study

India TV News  

As much as 45 per cent of people infected by the novel coronavirus behind the ongoing COVID-19 pandemic never show symptoms of the disease, according to a review of studies which suggests that the virus may silently damage the bodies of these asymptotic individuals. Scientists, including Eric Topol from the Scripps Research Translational Institute in the US, analysed public datasets …

WHO Creates 'Confusion' About Asymptomatic Spread. Here's What We Know
4 years, 7 months ago

WHO Creates 'Confusion' About Asymptomatic Spread. Here's What We Know

NPR  

WHO Creates 'Confusion' About Asymptomatic Spread. "From the data we have it still seems to be rare that an asymptomatic actually transmits onward to a secondary individual," said Maria Van Kerkhove, technical lead for WHO's health emergencies program. Sponsor Message Here's what we currently know and do not know about asymptomatic transmission: 1) How many people who get infected with …

Why Does Covid-19 Make Some People So Sick? Ask Their DNA
55 years ago

Why Does Covid-19 Make Some People So Sick? Ask Their DNA

Wired  

SARS-CoV-2, the pandemic coronavirus that surfaced for the first time in China last year, is an equal opportunity invader. To understand what accounts for these differences, scientists have been scouring the patchy epidemiological data coming out of hotspots like China, Italy, and the US, looking for patterns in patients’ age, race, sex, socioeconomic status, behaviors, and access to health care. …

Is It Possible That You Had The Coronavirus Earlier This Year?
4 years, 9 months ago

Is It Possible That You Had The Coronavirus Earlier This Year?

Huff Post  

nadia_bormotova via Getty Images Wondering if that bad cold or respiratory illness you had earlier this year was really COVID-19? Many urgent care centers, testing sites and doctors’ offices can take patients’ blood and send it to a lab to analyze for a previous COVID-19 infection. Some people have also reported contracting the coronavirus again after they’ve been sick one …

Immune response from Australia's first COVID-19 cases shows body's ability to fight and recover from virus
4 years, 9 months ago

Immune response from Australia's first COVID-19 cases shows body's ability to fight and recover from virus

Firstpost  

More than 80 percent of COVID-19 cases are mild-to-moderate, understanding the immune response in these cases are important for research. “We looked at the whole breadth of the immune response in this patient using the knowledge we have built over many years of looking at immune responses in patients hospitalized with influenza,” Dr Nguyen said. “Three days after the patient …

Australian researchers discover how body's immune system fights coronavirus COVID-19
4 years, 9 months ago

Australian researchers discover how body's immune system fights coronavirus COVID-19

ABC  

Understanding how an enemy works is the first step towards defeating it. "It's the first paper that shows the body can give immunity and fight back and recover," researcher Carolien van de Sandt said. "This information will allow us to evaluate any vaccine candidate as in an ideal world the vaccine should mimic our body's immune response," Professor Kedzierska said. …

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