AstraZeneca announces positive results from clinical trial of COVID-19 prevention drug
3 years, 4 months ago

AstraZeneca announces positive results from clinical trial of COVID-19 prevention drug

Firstpost  

This trial has 5,197 participants who had not been exposed and showed a 77-percent reduced risk of developing symptomatic disease with no severe cases recorded. Drug firm AstraZeneca on Friday announced positive results from a trial of a treatment for Covid-19 symptoms. A new trial of 5,197 participants who had not been exposed showed a 77-percent reduced risk of developing symptomatic disease, with no severe cases recorded, Astra said in a statement. The data show that one dose could “quickly and effectively prevent symptomatic Covid-19”, said Myron Levin, principal trial investigator.

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AstraZeneca removes its Covid vaccine worldwide after rare and dangerous side effect linked to 80 deaths in Britain was admitted in court papers
8 months ago

AstraZeneca removes its Covid vaccine worldwide after rare and dangerous side effect linked to 80 deaths in Britain was admitted in court papers

Daily Mail  

AstraZeneca is removing its Covid vaccine worldwide, months after the pharmaceutical giant admitted that it can cause a rare and dangerous side effect. The vaccine, once heralded as a 'triumph for British science', has come under intense scrutiny in recent months for a very rare side effect causing blood clots and low blood platelet counts. The AstraZeneca jab was the …

EU regulator advises AstraZeneca’s COVID drug be cleared
2 years, 9 months ago

EU regulator advises AstraZeneca’s COVID drug be cleared

Associated Press  

LONDON — The European Union’s drug regulator said Thursday it was recommending that an antibody medication developed by AstraZeneca be authorized to help some vulnerable people avoid getting sick with the coronavirus. The agency said it had assessed data on the drug from more than 5,000 people and found Evusheld reduced the risk of infection by 77%, with protection estimated …

AstraZeneca asks FDA to authorize COVID antibody treatment
3 years, 3 months ago

AstraZeneca asks FDA to authorize COVID antibody treatment

LA Times  

AstraZeneca has asked the Food and Drug Administration to authorize the emergency use of an antibody treatment to prevent COVID-19. AstraZeneca, the drugmaker that developed one of the first COVID-19 vaccines, has asked the U.S. Food and Drug Administration to authorize the emergency use of a first-of-a-kind antibody treatment to prevent the disease. The Anglo-Swedish company said Tuesday that the …

AstraZeneca Covid-19 vaccine shows 74% efficacy in large US trial
3 years, 3 months ago

AstraZeneca Covid-19 vaccine shows 74% efficacy in large US trial

India Today  

AstraZeneca Plc's Covid-19 vaccine demonstrated 74% efficacy at preventing symptomatic disease, a figure that increased to 83.5% in people aged 65 and older, according to long-awaited results of the company's US clinical trial published on Wednesday. Overall efficacy of 74% was lower than the interim 79% figure reported by the British drugmaker in March, a result AstraZeneca revised days later …

AstraZeneca tests Covid booster shots against Beta-variant
3 years, 6 months ago

AstraZeneca tests Covid booster shots against Beta-variant

India TV News  

British-Swedish biopharmaceutical firm AstraZeneca has in partnership with the University of Oxford rolled out human trials for booster shots against Beta Covid variant. The booster shot, named AZD2816, will be administered to individuals who have previously been fully vaccinated with two doses of AstraZeneca vaccine/Vaxzervia or an mRNA vaccine, at least three months after their last injection. AZD2816 has been …

AstraZeneca revises COVID-19 vaccine efficacy to 76% after US panel flags issues
3 years, 9 months ago

AstraZeneca revises COVID-19 vaccine efficacy to 76% after US panel flags issues

Firstpost  

The revised figures comes a day after an independent panel in the US accused AstraZeneca of cherry-picking data in determining the protection offered by its vaccine Washington: AstraZeneca insists that its COVID-19 vaccine is strongly effective even after counting additional illnesses in its disputed US study, the latest in an extraordinary public rift with American officials. Some experts said the …

New AstraZeneca report says vaccine was 76% effective in preventing Covid-19 symptoms
3 years, 9 months ago

New AstraZeneca report says vaccine was 76% effective in preventing Covid-19 symptoms

CNN  

CNN — Drug giant AstraZeneca updated its data on how well its coronavirus vaccine works, saying late Wednesday the vaccine showed 76% efficacy against symptomatic coronavirus disease and 100% efficacy against severe or critical disease or the need for hospitalization. On Tuesday, the independent Data and Safety Monitoring Board that reviews data from multiple Covid-19 vaccine candidates expressed concern over …

A top health official warned relaxing Covid-19 measures threatens progress. A day later, more states said they were easing restrictions
3 years, 9 months ago

A top health official warned relaxing Covid-19 measures threatens progress. A day later, more states said they were easing restrictions

CNN  

CNN — The emergence of Covid-19 variants makes reopening efforts in the United States a riskier proposition, an infectious disease expert said Wednesday. A month ago, the seven-day average was about 1.5 million doses per day, according to a CNN analysis of CDC data. Philadelphia cancels at least 11,000 invalid vaccine appointments Philadelphia canceled thousands of Covid-19 vaccine appointments at …

AstraZeneca lowers COVID-19 vaccine efficacy slightly to 76% after U.S. criticism
3 years, 9 months ago

AstraZeneca lowers COVID-19 vaccine efficacy slightly to 76% after U.S. criticism

LA Times  

AstraZeneca reported a slightly lower efficacy rate for its COVID-19 vaccine after the results of an American clinical trial were criticized as outdated, raising further questions over the controversial shot and whether it will be approved in the U.S. The company said the shot was 76% effective in its U.S. trial in a statement Thursday, after an independent monitoring board …

AstraZeneca COVID-19 Vaccine Trial Data Questioned By Safety Board
3 years, 9 months ago

AstraZeneca COVID-19 Vaccine Trial Data Questioned By Safety Board

NPR  

AstraZeneca COVID-19 Vaccine Trial Data Questioned By Safety Board Enlarge this image toggle caption Matthias Schrader/AP Matthias Schrader/AP A safety board overseeing AstraZeneca's COVID-19 vaccine trial is raising concerns about the company's data. If the pharmaceutical company did include outdated information from that trial, that could provide an "incomplete view of the efficacy data," the NIAID said. The pharmaceutical company …

AstraZeneca may have used outdated info in Covid-19 vaccine trial, says US
3 years, 9 months ago

AstraZeneca may have used outdated info in Covid-19 vaccine trial, says US

India Today  

Results from a US trial of AstraZeneca's Covid-19 vaccine may have included "outdated information" and that could mean the company provided an incomplete view of efficacy data, American federal health officials said early Tuesday. AstraZeneca reported Monday that its Covid-19 vaccine provided strong protection among adults of all ages in a long-anticipated US study, a finding that some experts hoped …

AstraZeneca vaccine trial results may have included outdated info, U.S. officials say
3 years, 9 months ago

AstraZeneca vaccine trial results may have included outdated info, U.S. officials say

LA Times  

AstraZeneca may have included “outdated information” in touting the effectiveness of its COVID-19 vaccine in a U.S. study, federal health officials said Tuesday in an unusual public rift that could further erode confidence in the shot. But shortly after midnight, the National Institutes of Health issued a statement saying the independent monitors that oversee the study had “expressed concern that …

Oxford-AstraZeneca Vaccine Effective Against Severe Covid-19, New Trial in US Confirms
3 years, 9 months ago

Oxford-AstraZeneca Vaccine Effective Against Severe Covid-19, New Trial in US Confirms

News 18  

A large trial in the US and two South American countries of the Oxford-AstraZeneca vaccine has shown 79 per cent efficacy rate at preventing symptomatic COVID-19 and 100 per cent effectiveness in stopping severe disease and hospitalisation, the biotech firm said on Monday. The vaccine’s efficacy was consistent across ethnicity and age, and in participants aged 65 years and over, …

U.S. data shows AstraZeneca’s vaccine is effective for all ages
3 years, 9 months ago

U.S. data shows AstraZeneca’s vaccine is effective for all ages

The Hindu  

A phase 3 trial of the AstraZeneca vaccine candidate in the United States has revealed an efficacy of 79%, when both doses were administered 4 weeks apart. ‘No safety concerns’ The U.S. trial, which recruited over 32,000 volunteers across all age groups, showed that the vaccine is 79% effective against symptomatic COVID-19, and 100% effective against severe, or critical symptomatic …

AstraZeneca vaccine is 79% effective against symptomatic Covid-19, company says
3 years, 9 months ago

AstraZeneca vaccine is 79% effective against symptomatic Covid-19, company says

CNN  

CNN — AstraZeneca’s Covid-19 vaccine showed 79% efficacy against symptomatic disease and 100% efficacy against severe disease and hospitalization in a new, US-based clinical trial, the company said Monday. Evans called previous assertions that the vaccine may be ineffective in older ages”totally unjustified.” The Oxford-AstraZeneca vaccine became the subject of controversy earlier in the month when a number of European …

AstraZeneca Vaccine Can Prevent COVID-19, Late-Stage Study Says
3 years, 9 months ago

AstraZeneca Vaccine Can Prevent COVID-19, Late-Stage Study Says

NPR  

AstraZeneca Vaccine Can Prevent COVID-19, Late-Stage Study Says Enlarge this image toggle caption Finnbarr Webster/Getty Images Finnbarr Webster/Getty Images Preliminary results from a late-stage study examining the efficacy of the Oxford-AstraZeneca vaccine indicate it is significantly effective at preventing severe illness from COVID-19. Results of the trial, which involved more than 32,000 volunteers, showed two doses of the vaccine administered …

AstraZeneca’s vaccine found to be 79% effective, with no safety issues, in U.S. trial
3 years, 9 months ago

AstraZeneca’s vaccine found to be 79% effective, with no safety issues, in U.S. trial

LA Times  

AstraZeneca’s vaccine was 79% effective at preventing any COVID-19 symptoms and 100% at preventing severe ones, and had no safety issues with blood clots in large-scale U.S. trials, the company said Monday. “The vaccine was well-tolerated, and the independent data safety monitoring board identified no safety concerns related to the vaccine,” the company said in a statement, adding: “The DSMB …

AstraZeneca, US agree 500,000 more supplies of COVID-19 antibody cocktail
3 years, 9 months ago

AstraZeneca, US agree 500,000 more supplies of COVID-19 antibody cocktail

Live Mint  

AstraZeneca will supply up to half a million extra doses of its experimental antibody-based COVID-19 combination therapy to the United States, in a bright spot for the company after more governments suspended use of its vaccine over safety fears. The Anglo-Swedish drugmaker said on Tuesday the $205 million U.S. extension for 500,000 antibody doses builds on a contract agreed with …

AstraZeneca suspensions: What you should know, in 500 words
3 years, 9 months ago

AstraZeneca suspensions: What you should know, in 500 words

Al Jazeera  

Which countries have stopped using the vaccine? Several countries, mostly European, have temporarily suspended the use of AstraZeneca’s COVID-19 vaccine over fears it may have caused some recipients to develop blood clots. Norway announced it was also suspending AstraZeneca over reports of possible serious side effects, including bleeding, blood clots and a low blood platelet count. In response to the …

EU drug agency chief insists AstraZeneca COVID-19 vaccine benefit outweighs risk
3 years, 9 months ago

EU drug agency chief insists AstraZeneca COVID-19 vaccine benefit outweighs risk

LA Times  

The European Union’s drug regulator insisted Tuesday that there is “no indication” the AstraZeneca vaccine causes blood clots as governments around the world faced the grimmest of dilemmas: push on with a vaccine known to save lives or suspend its use over reports of clotting in some recipients. “We are still firmly convinced that the benefits of the AstraZeneca vaccine …

AstraZeneca expects updated COVID-19 vaccine by autumn
3 years, 10 months ago

AstraZeneca expects updated COVID-19 vaccine by autumn

Associated Press  

LONDON — AstraZeneca said Thursday it expects to have a new version of its COVID-19 vaccine ready for use by this autumn as drugmakers respond to concerns about emerging variants of the disease that may be more transmissible or resistant to existing vaccines. The comments came as CEO Pascal Soriot defended the company’s efforts to develop and ramp up production …

AstraZeneca says its coronavirus vaccine can stop severe disease despite 'limited' success against South African variant
3 years, 11 months ago

AstraZeneca says its coronavirus vaccine can stop severe disease despite 'limited' success against South African variant

ABC  

British company AstraZeneca says it believes its COVID-19 vaccine developed with Oxford University can protect against severe disease caused by the South African variant of the virus. Key points: Around 2,000 people took part in the trial Around 2,000 people took part in the trial None of the participants were hospitalised or died after receiving the vaccine None of the …

AstraZeneca says its vaccine should work against new coronavirus strain
4 years ago

AstraZeneca says its vaccine should work against new coronavirus strain

LA Times  

The head of drugmaker AstraZeneca, whose COVID-19 vaccine candidate is expected to be authorized this week for use in Britain, says researchers believe the shot will be effective against the new coronavirus strain driving a rapid surge in infections in the U.K. AstraZeneca Chief Executive Pascal Soriot also told the Sunday Times of London that its researchers have figured out …

AstraZeneca Covid-19 vaccine has ‘winning formula’: chief executive Pascal Soriot
4 years ago

AstraZeneca Covid-19 vaccine has ‘winning formula’: chief executive Pascal Soriot

Hindustan Times  

The Covid-19 vaccine developed by the British drugs group AstraZeneca and the University of Oxford has achieved a “winning formula” for efficacy, the company’s chief executive said on Sunday. The vaccine, currently being evaluated by Britain’s independent medicines regulator, provides “100 percent protection” against severe Covid disease requiring hospitalisation, Pascal Soriot said in an interview with the Sunday Times newspaper. …

AstraZeneca's dosage error casts a cloud of doubt around the entire COVID-19 clinical trial
4 years, 1 month ago

AstraZeneca's dosage error casts a cloud of doubt around the entire COVID-19 clinical trial

Firstpost  

Experts say the relatively small number of people in the low dose group makes it difficult to know if the effectiveness seen in the group is real or a statistical quirk. In the group that got two full doses, the vaccine appeared to be 62 percent effective. In a statement Wednesday, Oxford University said some of the vials used in …

AstraZeneca defends dosing error in covid-19 vaccine trial
4 years, 1 month ago

AstraZeneca defends dosing error in covid-19 vaccine trial

Live Mint  

A top executive at AstraZeneca PLC pushed back on Wednesday against criticism that the company failed to disclose enough data from a clinical trial of its Covid-19 vaccine earlier this week, and acknowledged skepticism about the vaccine’s 90% effectiveness in a group of patients who were accidentally given a lower dose than intended. The half-dose was only given to volunteers …

Does the AstraZeneca Vaccine Also Stop Covid Transmission?
55 years ago

Does the AstraZeneca Vaccine Also Stop Covid Transmission?

Wired  

Three Mondays in a row have now yielded three apparently effective and safe vaccines against the pandemic disease Covid-19. That protein helps the SARS-CoV-2 virus attack people’s cells; the mRNA, enfolded in proprietary bubbles of fat, teaches the human immune system to fight the virus instead. Pfizer’s version has an efficacy of above 90 percent, says a company press release; …

AstraZeneca-Oxford University's COVID-19 vaccine shows average efficacy of 70%, says manufacturer
4 years, 1 month ago

AstraZeneca-Oxford University's COVID-19 vaccine shows average efficacy of 70%, says manufacturer

Firstpost  

Additionally, the drug manufacturer said that another regiment of a half dose, followed by a full dose at least one month apart was 90 percent effective London: AstraZeneca said Monday that late-stage trials showed that its COVID-19 vaccine with Oxford University was up to 90 percent effective in preventing disease. A half dose of the vaccine followed by a full …

AstraZeneca Says Covid-19 Vaccine Shows Average 70% Efficacy
4 years, 1 month ago

AstraZeneca Says Covid-19 Vaccine Shows Average 70% Efficacy

News 18  

British drugs group AstraZeneca and the University of Oxford on Monday said their jointly-developed vaccine against Covid-19 has shown “an average efficacy of 70 percent” in trials. “This vaccine’s efficacy and safety confirm that it will be highly effective against Covid-19 and will have an immediate impact on this public health emergency,” AstraZeneca chief executive Pascal Soriot said in a …

AstraZeneca COVID-19 vaccine can be 90% effective, results show
4 years, 1 month ago

AstraZeneca COVID-19 vaccine can be 90% effective, results show

Al Jazeera  

UK group is the latest drugmaker to unveil positive interim data in a scientific race to curb a global pandemic. “This vaccine’s efficacy and safety confirm that it will be highly effective against COVID-19 and will have an immediate impact on this public health emergency,” AstraZeneca chief executive Pascal Soriot said in a statement on Monday. Monday’s statement said: “Positive …

AstraZeneca Oxford vaccine is 70% effective on average, data shows
4 years, 1 month ago

AstraZeneca Oxford vaccine is 70% effective on average, data shows

CNN  

CNN — Drugmaker AstraZeneca announced on Monday that its experimental coronavirus vaccine has shown an average efficacy of 70% in large-scale trials – the latest of several vaccine trials worldwide to post their results this month. AstraZeneca has pledged to “ensure broad and equitable access to the vaccine at no profit for the duration of the pandemic.” Speaking on CNBC …

AstraZeneca Covid vaccine: Experts have questions about the Phase 3 trial data
4 years, 1 month ago

AstraZeneca Covid vaccine: Experts have questions about the Phase 3 trial data

CNN  

CNN — Vaccine experts – including those who serve on advisory committees for the US Food and Drug Administration and the US Centers for Disease Control and Prevention – have questions about data released Monday by AstraZeneca about its Covid-19 vaccine. In its press release, AstraZeneca said a total of 131 study participants developed Covid-19 but did not say how …

Regeneron, Used to Treat Trump's Covid-19, Announces More Positive Results for Covid-19 Treatment
4 years, 2 months ago

Regeneron, Used to Treat Trump's Covid-19, Announces More Positive Results for Covid-19 Treatment

News 18  

Regeneron, the US biotech firm that supplied synthetic antibodies to treat President Donald Trump’s Covid-19, announced Wednesday it had more positive results to show from an ongoing clinical trial. The company had previously announced results for 275 people in its late-stage study of non-hospitalized Covid-19 patients on REGN-COV2, and said data from an additional 524 people bore out the trend. …

AstraZeneca Resumes Its COVID-19 Vaccine Trials In The U.K.
4 years, 3 months ago

AstraZeneca Resumes Its COVID-19 Vaccine Trials In The U.K.

NPR  

AstraZeneca Resumes Its COVID-19 Vaccine Trials In The U.K. Enlarge this image toggle caption Alastair Grant/AP Alastair Grant/AP Drugmaker AstraZeneca announced Saturday that its COVID-19 vaccine studies have resumed in the United Kingdom, though not yet in the United States. The vaccine trials had been placed on hold around the world earlier in the week after a U.K. participant in …

Coronavirus | Vaccine trial volunteer had neurological symptoms, says AstraZeneca CEO
4 years, 4 months ago

Coronavirus | Vaccine trial volunteer had neurological symptoms, says AstraZeneca CEO

The Hindu  

AstraZeneca said a woman in the United Kingdom had symptoms consistent with a rare but serious spinal inflammatory disorder, which led to the British drugmaker's decision to stop its clinical study of the new coronavirus vaccine, Stat News reported on Wednesday. The participant was recovering and will likely be discharged from the hospital as early as today, according to Stat …

Oxford Covid Vaccine: Trial volunteer had neurological symptoms, says AstraZeneca CEO
4 years, 4 months ago

Oxford Covid Vaccine: Trial volunteer had neurological symptoms, says AstraZeneca CEO

India Today  

AstraZeneca said a woman in the United Kingdom had symptoms consistent with a rare but serious spinal inflammatory disorder, which led to the British drugmaker's decision to stop its clinical study of the new coronavirus vaccine, Stat News reported on Wednesday. The participant was recovering and will likely be discharged from the hospital as early as today, according to Stat …

Oxford Covid-19 vaccine trial on hold in UK after unexplained illness in volunteer
4 years, 4 months ago

Oxford Covid-19 vaccine trial on hold in UK after unexplained illness in volunteer

India Today  

AstraZeneca Plc on Tuesday said it has paused a late-stage trial of one of the leading Covid-19 vaccine candidates after an unexplained illness in a study participant. "Our standard review process was triggered and we voluntarily paused vaccination to allow review of safety data by an independent committee," company spokeswoman Michele Meixell said in an emailed statement. The companies, including …

Britain's AstraZeneca Tops Estimates as Coronavirus Vaccine Hopes Persist
4 years, 5 months ago

Britain's AstraZeneca Tops Estimates as Coronavirus Vaccine Hopes Persist

News 18  

Britain's AstraZeneca bettered second-quarter sales and profit estimates on Thursday, thanks to strong sales during the lockdowns from the drugmaker's diverse product line-up, which now includes a front-running coronavirus vaccine candidate. Shares of London's most valuable listed company on Thursday rose 3% at 88.6 pounds after product sales of $6.05 billion in the three months ended June 30 surpassed analysts' …

COVID-19 vaccine candidates with early human-trial data
4 years, 6 months ago

COVID-19 vaccine candidates with early human-trial data

Live Mint  

A COVID-19 vaccine developed by German biotech firm BioNTech and US pharmaceutical giant Pfizer has shown potential and was found to be well tolerated in early-stage human trials, the companies said on Wednesday. The following rivals have released early-stage trial data for potential COVID-19 vaccines, or are expected to publish soon: Moderna Moderna Inc said in May that its vaccine …

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