Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients
4 years, 4 months ago

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients

NPR  

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients Enlarge this image toggle caption Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Three new studies strongly support using inexpensive and widely available drugs to treat people who are seriously ill with COVID-19. Sponsor Message "Giving steroids to COVID-19 could have been quite scary," says Dr. Derek Angus, a critical care specialist at the University of Pittsburgh Medical Center. That advance was great news, but those findings created a conundrum for Angus and other researchers who were running their own studies of steroids in COVID-19 patients. Sponsor Message "I think it's good news to have a strong, clear signal on what is a widely available, inexpensive class of therapies," Angus says.

Research Patients Studies Ill Steroids  covid19  research  drugs  seriously  studies  widely  inexpensive  lives  patients  save  angus  trials  ill  steroids

History of this topic

Govt Issues Revised Covid Guidelines on Use of Drugs, Masks for Children
2 years, 11 months ago

Govt Issues Revised Covid Guidelines on Use of Drugs, Masks for Children

News 18  

Use of antivirals or monoclonal antibodies is not recommended for those less than 18 years of age, irrespective of severity of Covid infection, and if steroids are used, they should be tapered over 10 to 14 days, subject to clinical improvement, the government said on Thursday. In the ‘Revised Comprehensive Guidelines for Management of COVID-19 in Children and Adolescents ’, …

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment
2 years, 11 months ago

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment

News 18  

India has cut down on the use of the experimental drug Remdesivir and immunosuppressive drug Tocilizumab for the treatment of Covid-19. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with Covid-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the overuse of steroids, the protocol for …

WHO adds new drugs to COVID treatments amid Omicron surge
2 years, 11 months ago

WHO adds new drugs to COVID treatments amid Omicron surge

Al Jazeera  

Latest recommendations prompt new calls for patent waivers to allow more people access to treatments. The drug baricitinib, which is also used to treat rheumatoid arthritis, is “strongly recommended” for patients with severe or critical COVID-19, in combination with corticosteroids, the UN agency’s panel of international experts said in the guidelines which were published by the British Medical Journal on …

Explained | Why has the Centre revised the protocol for mild COVID-19 cases, and which drugs are not recommended anymore?
3 years, 6 months ago

Explained | Why has the Centre revised the protocol for mild COVID-19 cases, and which drugs are not recommended anymore?

The Hindu  

The story so far: The Union Health Ministry has revised its guidelines for the treatment of COVID-19 patients, particularly for the use of steroids, with doctors reporting a worrying rise in medical complications, such as mucormycosis, due to the abuse of drugs and therapies during treatment. The revised guidelines, issued on May 27, recommend the use of antipyretics for fever …

Govt issues guidelines on Covid in children; suggests rational use of CT scan, discourages Remdesivir
3 years, 7 months ago

Govt issues guidelines on Covid in children; suggests rational use of CT scan, discourages Remdesivir

India Today  

Comprehensive guidelines for the management of Covid-19 among children have been issued by the central government in which Remdesivir has not been recommended and rational use of HRCT imaging has been suggested. "However, any additional information gained from HRCT scan of the chest often has little impact on treatment decisions, which are based almost entirely on clinical severity and physiological …

DGHS issues COVID-19 treatment guidelines: Here is what document recommends on Remdesivir, Tocilizumab
3 years, 7 months ago

DGHS issues COVID-19 treatment guidelines: Here is what document recommends on Remdesivir, Tocilizumab

Firstpost  

Among the drugs and treatment methods that have been removed from the recommendations are Ivermectin, Azithromycin and plasma therapy The Union health ministry has issued guidelines on management of COVID-19 patients, dropping many drugs which have been widely used for treatment until now. While Remdesivir has been granted Emergency Use Authorisation, Tocilizumab has been approved for off-label use only FOLLOW …

Steroids without supplements slow cure for ex-covid patients
3 years, 7 months ago

Steroids without supplements slow cure for ex-covid patients

Deccan Chronicle  

HYDERABAD: Heavy intake of steroids with no vitamin and immune supplementation has led to further deterioration of health of Covid19-recovered patients. They are reporting back to hospitals with complaints of black fungus, urinary tract infection, recurrent diarrhea and compromised lung-functioning. Dr Sai Kumar Katam, president of the Doctor of Pharmacy Association explains, "The highest use of steroids namely dexamethasone and …

Mumbai: Doctors flag indiscriminate use of steroids, antibiotics in Covid-19 treatment
3 years, 8 months ago

Mumbai: Doctors flag indiscriminate use of steroids, antibiotics in Covid-19 treatment

Hindustan Times  

A 43-year-old man from Andheri was prescribed a cocktail of antibiotics, antiviral, and steroids on his first consultation with a local physician when he developed symptoms and was suspected of Covid-19. Indiscriminate use “Starting patients on steroids early is harmful for them,” said infectious disease expert Dr Tanu Singhal from Kokilaben Dhirubhai Ambani Hospital where the 43-year-old man and the …

Delhi hospital sees increase in deadly fungal infection among Covid-19 patients
3 years, 8 months ago

Delhi hospital sees increase in deadly fungal infection among Covid-19 patients

Hindustan Times  

A city hospital has reported an increase in the number of cases of a rare fungal infection triggered by the Coronavirus disease as the cases of the viral infection has increased exponentially in the city. Doctors say that use of steroids in the treatment of Covid-19 patients might weaken the immune system of the already sick patients resulting in the …

Self-medication can increase Covid severity, warn doctors
3 years, 8 months ago

Self-medication can increase Covid severity, warn doctors

India Today  

With the unavailability of Covid emergency treatment across the country due to a surge in cases, the issue of self-medication has become a talking point. Popping antivirals, steroids and antibiotics besides injecting antivirals like remdesivir without consulting a doctor can lead to the severity in Covid-19, doctors at Post Graduate Institute of Medical Education and Research have warned. ONLY 10-15% …

Steroids used in Covid treatmet leading to fungal infections in few patients
4 years ago

Steroids used in Covid treatmet leading to fungal infections in few patients

Deccan Chronicle  

Hyderabad: Steroids used in the treatment of Covid-19 are causing severe side-effects in a few patients which is leading to fungal infection. Among Covid-19 recovered patients, fungal infection is found in those suffering from ENT problems, diabetes, kidney problems, sinusitis and dental problems. Dr Srinivas Kishore Sistla, consultant ENT surgeon and sleep specialist at Star Hospitals, said doctors had seen …

Health experts clash over use of certain drugs for COVID-19
4 years, 1 month ago

Health experts clash over use of certain drugs for COVID-19

Associated Press  

Health officials around the world are clashing over the use of certain drugs for COVID-19, leading to different treatment options for patients depending on where they live. On Friday, a World Health Organization guidelines panel advised against using the antiviral remdesivir for hospitalized patients, saying there’s no evidence it improves survival or avoids the need for breathing machines. Within the …

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists
4 years, 1 month ago

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists

News 18  

Most adults with moderate-to-severe COVID-19 have a suppressed immune response against the novel coronavirus rather than life-threatening hyper-inflammation, according to a study which suggests steroids such as dexamethasone should be reserved for the sickest patients. According to the research, published in the journal Science Advances, fewer than 5 per cent of the COVID-19 patients, including some of the sickest individuals, …

'Proning' Covid Patients Seems to Save Lives. But How Many?
4 years, 1 month ago

'Proning' Covid Patients Seems to Save Lives. But How Many?

Wired  

The pandemic continues to rage in the US, and the number of people hospitalized with Covid-19 has now surpassed its prior peaks of about 60,000 in April and July. In 1976, a community ICU nurse in central Michigan named Margaret Piehl and Robert Brown, a doctor who had served in Vietnam, co-authored a paper detailing their observations that prone positioning …

Treatment for 6 months needed post Covid-19
4 years, 2 months ago

Treatment for 6 months needed post Covid-19

Deccan Chronicle  

Hyderabad: Fifteen to 20 per cent of Covid-19 recovered patients are coming back to hospitals with complaints of lung fibrosis, clotting in blood vessels, low functioning of kidney and heart and paralytic attack. Gandhi Hospital which has been the main centre in Telangana state for Covid-19 treatment is seeing many patients return with complaints. With so many people getting infected …

Steroids to Covid-19 Patients Who Don't Require Oxygen May Increase Severity: PGIMER
4 years, 3 months ago

Steroids to Covid-19 Patients Who Don't Require Oxygen May Increase Severity: PGIMER

News 18  

The Post Graduate Institute of Medical Education and Research, Chandigarh has noted that the seriousness of the COVID patients coming to hospitals has surged recently. One of the reasons observed behind the surge is the indiscriminate use of steroids in the cases of COVID-19 at an initial stage, the institute stated on Thursday. “It has been observed by experts here …

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients
4 years, 3 months ago

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients

NPR  

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients Enlarge this image toggle caption Nati Harnik/AP Nati Harnik/AP Editor's note: Since we published this story, Trump's physician said that the president has completed his treatment for COVID-19. The steroid, dexamethasone, is now part of the "standard of care" for COVID-19, said Dr. Celine Gounder, assistant professor …

Dexamethasone: What is the new life-saving coronavirus drug?
4 years, 3 months ago

Dexamethasone: What is the new life-saving coronavirus drug?

The Independent  

Sign up to our free Living Well email for advice on living a happier, healthier and longer life Live your life healthier and happier with our free weekly Living Well newsletter Live your life healthier and happier with our free weekly Living Well newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. …

(Explained) Trump’s Covid-19 treatments: Remdesivir, dexamethasone, antibody therapy, and more
4 years, 3 months ago

(Explained) Trump’s Covid-19 treatments: Remdesivir, dexamethasone, antibody therapy, and more

CNN  

CNN — President Trump’s physicians are giving him several different treatments – including investigational drugs – in the hope of relieving his Covid-19 symptoms and possibly shorten his course of illness. Dexamethasone President Trump was given the corticosteroid drug dexamethasone on Saturday after his oxygen level transiently dipped, White House physician Dr. Sean Conley said during a briefing on Sunday. …

Advances In ICU Care Are Saving More Patients Who Have COVID-19
4 years, 3 months ago

Advances In ICU Care Are Saving More Patients Who Have COVID-19

NPR  

Advances In ICU Care Are Saving More Patients Who Have COVID-19 Enlarge this image toggle caption Mark Felix/AFP via Getty Images Mark Felix/AFP via Getty Images If you think all the coronavirus news is bad, consider the uplifting story of Don Ramsayer. "We have very much replicated what's been seen worldwide, which is over time the mortality in ICUs have …

Steroids can be lifesaving for a few seriously ill COVID-19 patients, new studies suggests
4 years, 4 months ago

Steroids can be lifesaving for a few seriously ill COVID-19 patients, new studies suggests

Firstpost  

WHO warned against indiscriminate use of steroids, emphasizing that patients who are not severely ill are unlikely to benefit and may suffer side effects. International clinical trials published Wednesday confirm the hope that cheap, widely available steroid drugs can help seriously ill patients survive COVID-19, the illness caused by the coronavirus. Based on the new evidence, the World Health Organization …

Steroids Confirmed To Help Severely Ill Coronavirus Patients
4 years, 4 months ago

Steroids Confirmed To Help Severely Ill Coronavirus Patients

News 18  

New studies confirm that multiple types of steroids improve survival for severely ill COVID-19 patients, cementing the cheap drugs as a standard of care. An analysis of pooled results from seven studies, led by the World Health Organization and published Wednesday by the Journal of the American Medical Association, found that steroids reduced the risk of death in the first …

Common steroids reduce deaths among critically ill Covid-19 patients, new analysis confirms
4 years, 4 months ago

Common steroids reduce deaths among critically ill Covid-19 patients, new analysis confirms

CNN  

CNN — New research released on Wednesday confirms that common, affordable steroids can reduce deaths among critically ill Covid-19 patients. “The treatment with corticosteroids reduces mortality of 40% to 32%, that’s a 20% relative reduction, or if you like to a better way to think about it, an easier way to think about, it is that out of every hundred …

A blood test can tell which COVID-19 patient should get steroid treatment and who would react adversely to it
4 years, 5 months ago

A blood test can tell which COVID-19 patient should get steroid treatment and who would react adversely to it

Firstpost  

The study suggested steroid therapy may benefit patients with severe inflammation, but may negatively impact those with less severe inflammation COVID-19 has affected more than 15 million people in the world so far. Now, a group of researchers at the Albert Einstein College of Medicine say that the levels of CRP may have something to do with the effects of …

Seriously ill Covid patients showing major improvement after experimental treatment
4 years, 5 months ago

Seriously ill Covid patients showing major improvement after experimental treatment

NL Times  

Seriously ill Covid-19 patients can greatly benefit from treatment with corticosteroids, possibly in combination with a medicine that slows the functioning of the immune system, according to researchers from the Zuyderland Medical Center in Geleen and Heerlen. In their hospital, this experimental treatment reduced mortality in this patient group by as much as 65 percent, NOS reports. The doctors at …

COVID-19 research roundup: Benefits of steroid for severe COVID-19 confirmed; recovered still susceptible
4 years, 5 months ago

COVID-19 research roundup: Benefits of steroid for severe COVID-19 confirmed; recovered still susceptible

Firstpost  

The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus. Even during a pandemic, they said, when it might be tempting to simply “give all therapies a chance,” in order for patients’ outcomes to improve “there will need …

Centre includes includes dexamethasone drug in COVID-19 treatment protocol for moderate to severe cases
4 years, 6 months ago

Centre includes includes dexamethasone drug in COVID-19 treatment protocol for moderate to severe cases

Firstpost  

The updated protocol includes the advice to use dexamethasone as an alternative choice to methylprednisolone for managing moderate to severe cases of COVID-19. New Delhi: An inexpensive, widely used steroid dexamethasone was included in the treatment protocols for COVID-19 patients in moderate to severe stages of illness among other therapeutic measures by the Union health ministry on Saturday. According to …

The scientific process that Baba Ramdev’s potential Covid-19 medicine has to follow
4 years, 6 months ago

The scientific process that Baba Ramdev’s potential Covid-19 medicine has to follow

Hindustan Times  

Yoga guru Baba Ramdev created a sensation when he announced on Tuesday that his company Patanjali Ayurved has found a medicine for coronavirus disease Covid-19. Yoga guru Baba Ramdev and Patanjali Ayurved CEO Acharya Balkrishna launch an Ayurvedic medicine kit that they claimed can treat coronavirus patients within seven days, in Haridwar on Tuesday. The ministry of Ayurveda, Yoga & …

Dexamethasone: US doctors cast doubt on UK’s coronavirus ‘breakthrough’
4 years, 6 months ago

Dexamethasone: US doctors cast doubt on UK’s coronavirus ‘breakthrough’

The Independent  

Sign up to our free weekly IndyTech newsletter delivered straight to your inbox Sign up to our free IndyTech newsletter Sign up to our free IndyTech newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. Professor Peter Horby of Oxford University said the Recovery Trial project findings show the drug would, on …

Dexamethasone | WHO says more understanding needed on steroid
4 years, 6 months ago

Dexamethasone | WHO says more understanding needed on steroid

The Hindu  

The emergencies chief of the World Health Organization welcomed the news this week that dexamethasone, a cheap steroid, was shown in a British trial to reduce deaths among patients critically ill with the coronavirus, but said it was too soon to change how patients are treated. “It’s one of the breakthroughs we’re going to need to effectively deal with COVID-19, …

WHO moves to update Covid-19 guidance after ’major breakthrough’ in drug study
4 years, 6 months ago

WHO moves to update Covid-19 guidance after ’major breakthrough’ in drug study

Live Mint  

The World Health Organization said it was moving to update its guidelines on treating people stricken with Covid-19 to reflect results of a clinical trial that showed a cheap, common steroid can help save critically ill patients. Trial results announced on Tuesday by researchers in Britain showed dexamethasone, used since the 1960s to reduce inflammation in diseases such as arthritis, …

Dexamethasone shows promise in treatment of severely ill COVID-19 patients: All you need to know about the steroid drug
4 years, 6 months ago

Dexamethasone shows promise in treatment of severely ill COVID-19 patients: All you need to know about the steroid drug

Firstpost  

The Oxford University announced that dexamethasone, a common steroid drug, has shown promise in the treatment of severely ill COVID-19 patients by improving their survival rate by at least 20 percent The Oxford University announced that dexamethasone, a common steroid drug, has shown promise in the treatment of severely ill COVID-19 patients by improving their survival rate by at least …

COVID-19 'RECOVERY' Trial: Dexamethasone found life-saving in seriously-ill patients in preliminary tests
4 years, 6 months ago

COVID-19 'RECOVERY' Trial: Dexamethasone found life-saving in seriously-ill patients in preliminary tests

Firstpost  

As part of the Recovery trial, a range of potential treatments is being tested in consenting COVID-19 patients admitted to NHS hospitals in the UK. “This is the most important trial result for COVID-19 so far,” Chris Whitty, England’s Chief Medical Officer, said on Twitter about the findings of the UK-led clinical trial known as ‘RECOVERY’. “This is the first …

‘Breakthrough’: WHO hails steroid treatment for coronavirus
4 years, 6 months ago

‘Breakthrough’: WHO hails steroid treatment for coronavirus

Al Jazeera  

UK study shows dexamethasone reduces deaths by about 30 percent in critical COVID patients, some US doctors sceptical. The World Health Organization plans to update its guidelines on treating people stricken with coronavirus to reflect results of a clinical trial that showed a cheap, common steroid could help save critically ill patients. ‘Best piece of news’ Britain’s health minister on …

How dexamethasone might lead researchers to better COVID-19 treatments
4 years, 6 months ago

How dexamethasone might lead researchers to better COVID-19 treatments

LA Times  

The steroid drug dexamethasone can be lifesaving for patients with severe COVID-19. In preliminary clinical trial results announced Tuesday, patients on mechanical ventilators who were treated with the steroid dexamethasone were 35% less likely to die of COVID-19 than their counterparts who got standard care without the drug. A medication like dexamethasone is a “blunt instrument,” said Dr. Steven J. …

Dexamethasone could be the miracle drug to reduce COVID-19 mortality rate
4 years, 6 months ago

Dexamethasone could be the miracle drug to reduce COVID-19 mortality rate

Deccan Chronicle  

New Delhi: For countries battling high mortality rate due to the coronavirus pandemic, steroid Dexamethasone can be a boon, as researchers in England have claimed that it can reduce COVID-19 deaths by one-third in severely ill hospitalised patients. The chief investigators of the randomised evaluation of COVID -19 therapy trial said low-cost Dexamethasone reduces death by up to one-third in …

Indian doctors express cautious endorsement for dexamethasone for COVID-19
4 years, 6 months ago

Indian doctors express cautious endorsement for dexamethasone for COVID-19

The Hindu  

Indian doctors have said the reported success of dexamethasone — an inexpensive steroid that retails for less than ₹10 for 10 ml and is made by several Indian manufacturers — at curing COVID-19 patients on ventilators is good news for India. Scientists administering the WHO-administered RECOVERY trial — the largest global clinical trial — that is checking the ability of …

Major COVID-19 breakthrough: A cheap Dexamethasone drug 'reduces risk of death in ventilated patients'
4 years, 6 months ago

Major COVID-19 breakthrough: A cheap Dexamethasone drug 'reduces risk of death in ventilated patients'

India TV News  

A cheap, widely available steroid called dexamethasone reduced deaths by up to one third in severely ill hospitalized patients. “Dexamethasone must now be rolled out and accessed by thousands of critically ill patients around the world,” said Cammack, who had no role in the study. Researchers estimated that the drug would prevent one death for every eight patients treated while …

Coronavirus | Dexamethasone reduces deaths from COVID-19, say researchers in U.K.
4 years, 6 months ago

Coronavirus | Dexamethasone reduces deaths from COVID-19, say researchers in U.K.

The Hindu  

Researchers in the U.K. say they have the first evidence that a drug can improve COVID-19 survival: A steroid called dexamethasone reduced deaths by up to one third in severely ill hospitalised patients. The study is a large, strict test that randomly assigned 2,104 patients to get the drug and compared them with 4,321 patients getting only usual care. “The …

Coronavirus: £5 steroid dexamethasone 'reduces risk of death'
4 years, 6 months ago

Coronavirus: £5 steroid dexamethasone 'reduces risk of death'

Daily Mail  

Prime Minister Boris Johnson today hailed the 'biggest breakthrough yet' in the UK's coronavirus fight as officials announced they have found a drug that could save up to a third of critically-ill Covid-19 patients. In other coronavirus developments in Britain today: Two women travelling to New Zealand to visit a dying parent tested positive for Covid-19, ending the country's 24-day …

Dexamethasone reduces death risk in severe COVID-19 cases: Trial
4 years, 6 months ago

Dexamethasone reduces death risk in severe COVID-19 cases: Trial

Al Jazeera  

Steroid cuts risk of death by a third for patients on ventilators, by a fifth for those on oxygen, researchers say. “Based on these results, one death would be prevented by treatment of around 8 ventilated patients or around 25 patients requiring oxygen alone,” a University of Oxford statement said. Dexamethasone is inexpensive, on the shelf, and can be used …

Steroid drug: A ‘breakthrough’ in the fight against coronavirus?
4 years, 6 months ago

Steroid drug: A ‘breakthrough’ in the fight against coronavirus?

Al Jazeera  

UK has approved the drug use in the state-run health service and stockpiled 200,000 courses of the treatment. A cheap and widely-used steroid called dexamethasone has become the first drug shown to be able to save lives among COVID-19 patients in what scientists said is a “major breakthrough” in the coronavirus pandemic. “This is a result that shows that if …

Dexamethasone can improve COVID-19 survival, study shows
4 years, 6 months ago

Dexamethasone can improve COVID-19 survival, study shows

LA Times  

In a development that could dramatically shrink the death toll of the COVID-19 pandemic, British researchers have found that a cheap and readily available steroid prevented more than a third of the sickest patients from dying. If people are tempted to use it inappropriately, it “will cause much sicker patients,” said Dr. Steven J. O’Day, director of regional research at …

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients
4 years, 6 months ago

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients

NPR  

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients toggle caption John Minchillo/AP A low-cost anti-inflammatory drug appears to reduce the risk of death in patients with COVID-19. Sponsor Message "Dexamethasone reduced deaths by one-third in ventilated patients," according to a news release from the RECOVERY trial organizers, "and by one fifth in other patients receiving oxygen only." …

Why Covid-19 kills some young people
4 years, 9 months ago

Why Covid-19 kills some young people

CNN  

CNN — When 30-year-old Ben Luderer started to feel sick, he wasn’t that surprised. Brandy Luderer “Ben always said the nights had been the worst for him, he would sweat and when he laid down a certain way,” Brandy said. At one point, Ben texted his wife and said, “I’m struggling.” Brandy asked him if he needed to go back …

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