Indian scientists complete sequencing of 10,000 genomes for database
9 months, 3 weeks ago

Indian scientists complete sequencing of 10,000 genomes for database

India TV News  

Scientists have recently completed the sequencing of genomes from 10,000 individuals across diverse Indian communities. Why it matters Sequencing genomes—essentially mapping out an individual's genetic makeup—is crucial for shaping future healthcare strategies worldwide, both in treatment and prevention. The need for Indian solutions Union minister emphasised the importance of finding solutions tailored to Indian needs, given the country's emergence as a leader in scientific advancements. India's vast population comprises numerous distinct groups, making it essential to study their genetic variations.

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History of this topic

India sets up its first diabetes biobank. Why it matters
Top News
6 days, 19 hours ago

India sets up its first diabetes biobank. Why it matters

India Today  

India has launched its first-ever diabetes biobank in Chennai, a major step toward understanding and tackling one of the country's most pressing health concerns. By storing biological samples from across India, the biobank will help scientists study the genetic, lifestyle, and environmental factors behind diabetes. The MDRF biobank addresses this gap by housing over 1,50,000 biological samples, providing critical data …

Bengaluru start-up strives to bridge the indigenous data gap in precision oncology
1 month, 2 weeks ago

Bengaluru start-up strives to bridge the indigenous data gap in precision oncology

The Hindu  

In February this year, Union minister for health and family welfare Mansukh Mandaviya, citing the Indian Council of Medical Research-National Cancer Registry Programme, told the parliament that the estimated incidents of cancer are rising in India. 4baseCare, a Bengaluru based start-up, aims to bridge this data gap and has come up with a gene panel for the Indian population after …

Data — A healthy way to assess progress
8 months, 1 week ago

Data — A healthy way to assess progress

The Hindu  

The undoubtedly biggest story in healthcare in India last week, came of all things, from the Lancet. Going back to the COVID-19 pandemic, the Lancet said that another contentious issue is the lack of credibility of India’s continuing claim that only 0·48 million people died as a result of the COVID-19 pandemic, whereas the World Health Organisation and other estimates …

What can the 10,000 genome project tell us about India’s health | In Focus podcast
8 months, 2 weeks ago

What can the 10,000 genome project tell us about India’s health | In Focus podcast

The Hindu  

India announced recently, that it has completed the 10,000 genome project – a reference database of whole-genome sequences, from people in India. This project is seen as an important step to find out about genetic variants that are unique to India, to customise drugs and gene-based therapies, give us answers about certain diseases, and to provide a deeper insight into …

‘Underwhelming Indian genomics research, and gatekeeping’
8 months, 3 weeks ago

‘Underwhelming Indian genomics research, and gatekeeping’

The Hindu  

On March 9, 2024, Dr. Vinod Scaria wrote an article in science page of The Hindu urging for a strong regulatory crackdown to prevent Indian biological samples from being analyzed by foreign commercial entities. However, this article goes over and beyond patient advocacy, and wants a gatekeeping layer to prevent international commercial offerings from accessing any Indian genomics data. Here, …

Decoding the script: On the Genome India Project and its sequencing 10,000 Indian genomes
9 months, 3 weeks ago

Decoding the script: On the Genome India Project and its sequencing 10,000 Indian genomes

The Hindu  

The Genome India Project, a project funded and coordinated by the Department of Biotechnology, announced that it had finished sequencing 10,000 Indian genomes. This means that the complete genomes — the DNA blueprint that constitutes and maintains human bodies — from 10,000 individuals were analysed to create a ‘reference’ Indian human genome. In a way, the latest enterprise would be …

What is Genome Sequencing? How Study of 10,000 Individuals is a Watershed in India’s Healthcare
9 months, 3 weeks ago

What is Genome Sequencing? How Study of 10,000 Individuals is a Watershed in India’s Healthcare

News 18  

Indian scientists are close to completing reference genome, with sequencing of samples from 10,000 individuals from around 99 communities already done. Union science and technology minister Jitendra Singh said genome study or sequencing will determine the future healthcare strategies across the world, both therapeutically and prophylactically. “It can also help in identifying resistance indicating variants, for examples, genes that might …

Explained | What is genome sequencing and why does the Genome India Project matter?
1 year, 8 months ago

Explained | What is genome sequencing and why does the Genome India Project matter?

The Hindu  

The story so far: The Department of Biotechnology recently said that the exercise to sequence 10,000 Indian human genomes and create a database under the Centre-backed Genome India Project is about two-thirds complete. The process of whole-genome sequencing, made possible by the Human Genome Project, now facilitates the reading of a person’s individual genome to identify differences from the average …

10,000 Indian genomes to be sequenced by year-end
1 year, 8 months ago

10,000 Indian genomes to be sequenced by year-end

The Hindu  

The Genome India Project, a Centre-backed initiative to sequence 10,000 Indian human genomes and create a database, is about two-thirds through, said Rajesh Gokhale, Secretary, Department of Biotechnology. We expect the 10,000 genomes to be completely sequenced by the end of the year,” said Mr. Gokhale at a conference organised by the Association of Biotech-Led Enterprises, an industry group, on …

It feels a lot like 2020: What India is doing to avoid a China-like COVID surge
2 years ago

It feels a lot like 2020: What India is doing to avoid a China-like COVID surge

Firstpost  

The rising cases of coronavirus in China have put India on edge. Prime Minister Narendra Modi has urged people to wear masks in public places though they are not mandatory yet. Union Health Minister Mansukh Mandaviya said in Parliament that India had started a two per cent random sampling of international travellers coming to the country. Also, there will be …

Scientists condemn project to study ‘racial purity’ of Indian population
2 years, 6 months ago

Scientists condemn project to study ‘racial purity’ of Indian population

The Hindu  

Over a 100 leading biologists, historians, anthropologists and intellectuals have written a joint letter to the Ministry of Culture protesting its purported plans to fund a project to study “genetic similarities and differences in the DNA profiles of Indian population groups.” Last month media reports surfaced of a plan involving the Anthropological Survey of India, some scientists at the Lucknow-based …

India to Revise Genome Sequencing Strategy to Gauge Severity of Omicron Variant in Population
2 years, 11 months ago

India to Revise Genome Sequencing Strategy to Gauge Severity of Omicron Variant in Population

News 18  

A top official from the union health ministry has indicated that there has been an increasing trend in Covid-19 hospitalisations across the country as overall cases continue to rise. Therefore, a decision has been taken to sequence the genomes of all the patients admitted to the intensive care unit due to the infection and of those who have died because …

EXPLAINED: Why Genome Sequencing Results Take So Long, the Cost and its Importance in Public Health
2 years, 11 months ago

EXPLAINED: Why Genome Sequencing Results Take So Long, the Cost and its Importance in Public Health

News 18  

Omicron, the latest coronavirus variant fuelling the third wave of the pandemic in India, can be identified only through genome sequencing. But, as of now, genome sequencing results take anywhere between five and 12 days after samples are submitted. Highly equipped labs capable of carrying out a genome sequencing will need at least 300 samples to begin the process. Hence, …

Here's Why an Indian Gene Panel is the Need of the Hour in Cancer Treatment
3 years, 3 months ago

Here's Why an Indian Gene Panel is the Need of the Hour in Cancer Treatment

The Quint  

Despite advancements in precision-based cancer care, the standards of cancer treatment for patients in India have largely been limited to surgery, chemotherapy and radiation. This research is believed to be India’s largest and first population-specific tumour study derived from Whole Exome and Whole Transcriptome data of over 1500 cancer patients across 28 different cancer types. To discuss this milestone, The …

Genomic sequencing hubs must be made a permanent part of India’s pandemic response
3 years, 4 months ago

Genomic sequencing hubs must be made a permanent part of India’s pandemic response

Firstpost  

Public labs put into action by the INSACOG for this purpose are not adequately funded and have the capacity to process only 30,000 samples a month. To achieve the five percent sequencing target, India must process 75,000 samples a month which is 2.5 times the current scale. Making private sector labs a part of the genome sequencing process can help …

From sequencing to surveillance: How India's INSACOG track mutations in Covid-19
3 years, 5 months ago

From sequencing to surveillance: How India's INSACOG track mutations in Covid-19

Live Mint  

The Indian SARS-CoV-2 Genomics Consortium which is a national multi-agency consortium of Genome Sequencing Laboratories laboratories established by the Government of India on 30th December 2020. {{^adFree}} {{/adFree}} INSACOG has the following specific objectives: To ascertain the status of Variants of Interest and Variants of Concern in the country To establish sentinel surveillance and surge surveillance mechanisms for early detection …

Bring genomic sequencing into the pandemic fight
3 years, 6 months ago

Bring genomic sequencing into the pandemic fight

The Hindu  

If there is one tool in the COVID-19 pandemic response, which India has been slow in adoption and has used sub-optimally, it is genomic sequencing. Based upon the analysis of nearly 3,600 genomic sequence samples from November 2020 to April 2021, the authors have reported that by April 2021, the Delta variant became the most circulating variant in Delhi and …

B.1.617.2 becoming dominant variant in India, finds genome sequencing
3 years, 7 months ago

B.1.617.2 becoming dominant variant in India, finds genome sequencing

India Today  

The United Kingdom has been closely watching the movement of the sub-lineages of the B.1.617 variant that originated in India - B1617.1, B1617.2, and B.617.3. Experts in genomic sequencing of Covid-19 variants in India have now revealed that cases which show B.1.617.2 are slowly eclipsing almost all other variants, including B.1.1.7 -- the Kent variant that originated in the UK. …

‘Variant tracking an essential part of long-term strategy’: Satyajit Rath
3 years, 7 months ago

‘Variant tracking an essential part of long-term strategy’: Satyajit Rath

The Hindu  

Satyajit Rath was trained as a physician and a pathologist and has worked on mechanisms involved in the development and functioning of the immune system, in India and overseas, and later as a faculty member at the National Institute of Immunology in New Delhi. There is quite good evidence for SARS-CoV-2 virus that such ‘neutralising’ antibodies do protect better than …

Covid-19: What you need to know today
4 years ago

Covid-19: What you need to know today

Hindustan Times  

At the end of a year that’s been defined by the coronavirus disease pandemic, it is strange that governments around the world need to be reminded of this: the coronavirus does not follow their rules. Since December 1, for instance, according to the New York Times, the UK has sequenced 3,700 viral genomes, and the US “fewer than 40”. India …

Genome sequencing takes a hit in India
4 years ago

Genome sequencing takes a hit in India

Deccan Chronicle  

HYDERABAD: Beset with problems of importing the required chemicals, there was a decline in genome sequencing in India in October and November. It is not known if the United Kingdom variant of SARS-Cov 2 – VUI-202012/01 is in India while another variant 501.V2 has been identified in South Africa. We will have to aggressively take up sequencing again to verify.” …

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