Booster dose of six Covid vaccines safe, increases immunity: Lancet study
Deccan ChronicleNew Delhi: Six different COVID-19 boosters are safe and elicit strong immune response in people who have previously received a two-dose course of AstraZeneca or Pfizer vaccines, according to a study published in The Lancet journal. Two doses of AstraZeneca and Pfizer vaccines have shown 79 per cent and 90 per cent protection, respectively, against hospitalisation and death after six months in several studies, the researchers said. "The side effect data show all seven vaccines are safe to use as 3rd doses, with acceptable levels of inflammatory side effects like injection site pain, muscle soreness, fatigue," said Professor Saul Faust, trial lead from the University Hospital Southampton NHS Foundation Trust, UK. "Whilst all boosted spike protein immunogenicity after two doses of AstraZeneca, only AstraZeneca, Pfizer-BioNTech, Moderna, Novavax, Janssen and Curevac did so after two doses of Pfizer-BioNTech," Faust said. A randomised, phase 2 trial of the seven booster vaccines was conducted, with the third doses given 10-12 weeks after initial two-dose courses of AstraZeneca or Pfizer-BioNTech.