Top medical experts welcome move to remove plasma therapy from COVID-19 treatment
3 years, 7 months ago

Top medical experts welcome move to remove plasma therapy from COVID-19 treatment

Deccan Chronicle  

New Delhi: Several top medical experts have welcomed the Indian Council of Medical Research 's updated advisory released on Monday dropping the use of convalescent plasma from recommended treatment protocols for COVID-19. Sir Ganga Ram Hospital chairman Dr DS Rana said plasma therapy has failed to change the "course of mortality" and asserted that some scientists are also of the view that it is helping in promoting mutations and variants. Dr Sheeba Marwah, Assistant Professor and COVID-19 Nodal Officer, Department of Obstetrics and Gynaecology Vardhman Mahavir Medical College and Safdarjung Hospital said: "The current research being done globally using convalescent plasma of patients recovered from COVID-19 for treatment of new COVID-19 patients have not yielded any efficacious results when it comes to modifying the disease course or thwarting its progression to severe disease and averting mortality. As India's daily spike of coronavirus cases witnesses, a dip with only 2,63,533 fresh infections recorded in the last 24 hours, the number of deaths due to COVID-19 continues to remain alarmingly high with 4,329 more fatalities, the highest toll in a single day since the pandemic began.

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History of this topic

FDA revokes authorization for key anti-COVID drug, a blow for vulnerable Americans
1 year, 10 months ago

FDA revokes authorization for key anti-COVID drug, a blow for vulnerable Americans

LA Times  

A two-shot dose of Evusheld at a University of Washington Medicine clinic in Seattle. For her patients, she said, “it was kind of like being told the seat belts in your car won’t work anymore, and we’re not going to be able to replace them with anything.” In recent months, nine new subvariants of the dominant Omicron strain have proven …

Health Matters: Dear Drug Regulator, Silence is Not Always Golden, Esp on WHO Pausing Covaxin Supply
2 years, 8 months ago

Health Matters: Dear Drug Regulator, Silence is Not Always Golden, Esp on WHO Pausing Covaxin Supply

News 18  

On April 2, the World Health Organization suspended the supply of Bharat Biotech’s Covaxin through the UN agencies after finding issues with the “good manufacturing practices”. For the past 15 days, not only health journalists, but even commoners who got Covaxin jabs are hoping to hear from the country’s drug regulatory agency – Central Drugs Standard Control Organization. Eventually, the …

Health Matters: Don't Feel Guilty About Not Finding Remdesivir for Your Loved One. It Hardly Works
2 years, 11 months ago

Health Matters: Don't Feel Guilty About Not Finding Remdesivir for Your Loved One. It Hardly Works

News 18  

It was dinner time when she called for help. They don’t want to use it, but keep it.” Much before the outbreak of second wave, in November 2020, the World Health Organization issued a conditional recommendation against the use of Remdesivir in hospitalised patients, regardless of disease severity saying “there is currently no evidence that Remdesivir improves survival and other …

New COVID-19 treatment rules: India cuts down use of Remdesivir, Tocilizumab, multivitamins, steroids
2 years, 11 months ago

New COVID-19 treatment rules: India cuts down use of Remdesivir, Tocilizumab, multivitamins, steroids

Firstpost  

According to the new guidelines, Remdesivir may be considered only in patients who have completed 10 days since the start of the symptoms and require supplemental oxygen. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with COVID-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the …

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment
2 years, 11 months ago

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment

News 18  

India has cut down on the use of the experimental drug Remdesivir and immunosuppressive drug Tocilizumab for the treatment of Covid-19. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with Covid-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the overuse of steroids, the protocol for …

What you should know about treating Covid-19
3 years ago

What you should know about treating Covid-19

Live Mint  

Within a few weeks, the US could have access to the first antiviral pills to treat Covid-19, either from Pfizer Inc. or Merck & Co. and partner Ridgeback Biotherapeutics LP. Doctors say an initial step is to monitor symptoms to determine whether infected people could be considered at low or high risk for developing severe disease. Patients who don’t respond …

Curing with Blood: the Rise and Fall of Covid Convalescent Plasma Therapy
3 years, 2 months ago

Curing with Blood: the Rise and Fall of Covid Convalescent Plasma Therapy

News 18  

Early in the pandemic, scientists thought convalescent plasma might be a way to treat COVID-19. But growing evidence, including an international study published this week, shows convalescent plasma does not save lives of people critically ill with COVID-19. year more than 100 clinical trials had been conducted with convalescent plasma in people with COVID-19; about one-third of these studies had …

Use of plasma therapy for Covid may cause adverse events: Study
3 years, 3 months ago

Use of plasma therapy for Covid may cause adverse events: Study

Hindustan Times  

Even with doubtful efficacy, antibody-rich plasma from recovered Covid-19 patients continued to be used for the treatment of those suffering from the infection during the second wave of the pandemic, with people queuing up at plasma banks and looking for donors online. But a recent Canadian study published in the journal Nature has shown that not only did plasma therapy …

Monoclonal antibody treatment for COVID-19 could be a game changer
3 years, 6 months ago

Monoclonal antibody treatment for COVID-19 could be a game changer

The Hindu  

Monoclonal antibody treatment is now seen as a relatively effective and safer alternative in treating COVID-19 patients, with doctors stating that, as with any other drug, timing is very important for the administration of the therapy that’s touted as a game changer. “Monoclonal antibody treatment could prove to be a game changer in times to come if used at the …

Govt Issues Advisory for Rational Use of Remdesivir in Covid-19 Treatment
3 years, 6 months ago

Govt Issues Advisory for Rational Use of Remdesivir in Covid-19 Treatment

News 18  

The government on Monday issued an advisory for rational use of Remdesivir in COVID-19 treatment, underlining that the anti-viral drug must be advised by senior faculty members directly involved in the patient's care. To stop the misuse of Remdesivir, the government further recommended that if the drug is to be advised or ordered during odd hours, it should be done …

No evidence of Remdesivir's effectiveness, might be dropped as COVID-19 treatment: Dr DS Rana
3 years, 7 months ago

No evidence of Remdesivir's effectiveness, might be dropped as COVID-19 treatment: Dr DS Rana

Firstpost  

Ganga Ram hospital Chairperson Dr DS Rana said, “Medicines that do not have any activity to work, will have to be discontinued.” Ganga Ram hospital Chairperson Dr DS Rana on Tuesday said that Remdesivir is also being considered to be dropped from COVID-19 treatment soon as there is no evidence of its effectiveness in treating COVID-19 patients. While talking to …

Does India's trial and error approach to fighting mutating coronavirus need course correction?
3 years, 7 months ago

Does India's trial and error approach to fighting mutating coronavirus need course correction?

India Today  

The second wave continues to wreak havoc in India with over 4,500 deaths recorded in a day on Wednesday. The Indian Council of Medical Research decision came within days of a study published in The Lancet that suggested plasma therapy did not improve survival or other pre-specified clinical outcomes in patients. Interestingly, similar data from ICMR's own trials was released …

Delete and control: On ICMR's dropping of plasma therapy
3 years, 7 months ago

Delete and control: On ICMR's dropping of plasma therapy

The Hindu  

The Indian Council of Medical Research has finally dropped its espousal of convalescent plasma therapy as treatment for moderate COVID-19 in its latest guidelines. Last year, the ICMR, in one of the definitive clinical trials in the world, demonstrated that CPT neither saved lives nor improved patient outcomes but was equivocal about it in public. This gave leeway to some …

Not enough evidence to prove plasma therapy works: Top ICMR scientist on why India changed treatment protocol
3 years, 7 months ago

Not enough evidence to prove plasma therapy works: Top ICMR scientist on why India changed treatment protocol

India Today  

The Centre on Monday revised the clinical guidance for Covid-19 treatment, dropping the off-label use of convalescent plasma from the treatment protocol for adult patients. Dr Samiran Panda, Indian Council of Medical Research scientist who was also a part of the panel that dropped plasma therapy from Covid-19 management guidelines, told India Today that the decision was taken since anecdotal …

Why government has dropped plasma therapy for Covid-19
3 years, 7 months ago

Why government has dropped plasma therapy for Covid-19

India Today  

India has officially removed the use of convalescent plasma, popularly known as the plasma therapy, on Covid-19 patients from its clinical management guidelines for the disease. The previous guidelines allowed “off label” use of plasma therapy on Covid-19 patients during moderate stage within seven days of the onset of symptoms. WHY GOVERNMENT DROPPED PLASMA THERAPY Many a time, the prescription …

Found Ineffective, Plasma Therapy No Longer Recommended For Covid-19 Treatment
3 years, 7 months ago

Found Ineffective, Plasma Therapy No Longer Recommended For Covid-19 Treatment

News 18  

Days after various studies and expert panels suggested that plasma therapy on Covid-19 patients was found ineffective in reducing the progression to severe disease or death, the treatment protocol has been dropped from the clinical management guidelines, sources said. In the letter, which was also marked to ICMR chief Balram Bhargava and AIIMS Director Randeep Guleria, public health professionals alleged …

Govt removes plasma therapy as treatment for Covid-19 among adults
3 years, 7 months ago

Govt removes plasma therapy as treatment for Covid-19 among adults

India Today  

A government-appointed task force on Covid-19 on Monday removed plasma therapy from the treatment protocol for adult Covid-19 patients. In the revised clinical guidelines for management of adult Covid-19 patients, use of convalescent plasma therapy has been removed even as an 'off label treatment. Until now, India's Covid-19 treatment protocol allowed 'off label' use of convalescent plasma therapy but only …

COVID-19: Plasma therapy not found effective, likely to be dropped from clinical management guidelines
3 years, 7 months ago

COVID-19: Plasma therapy not found effective, likely to be dropped from clinical management guidelines

Firstpost  

The present guidelines allows ‘off label’ use of plasma therapy at the stage of early moderate disease, that is, within seven days of the onset of symptoms New Delhi: Plasma therapy on COVID-19 patients has not been found effective in reducing the progression to severe disease or death and is likely to be dropped from the clinical management guidelines, sources …

Plasma therapy not effective, likely to be dropped from clinical management guidelines on Covid-19
3 years, 7 months ago

Plasma therapy not effective, likely to be dropped from clinical management guidelines on Covid-19

India Today  

Plasma therapy on Covid-19 patients has not been found effective in reducing the progression to severe disease or death and is likely to be dropped from the clinical management guidelines, sources said. In the letter, which was also marked to ICMR chief Balram Bhargava and AIIMS Director Randeep Guleria, public health professionals alleged that the current guidelines on plasma therapy …

Stop irrational use of plasma, may develop more virulent strains of Covid, warn experts
3 years, 7 months ago

Stop irrational use of plasma, may develop more virulent strains of Covid, warn experts

India Today  

A group of doctors, public health officials and experts have written to the Centre’s principal scientific advisor along with the AIIMS chief and ICMR chief, raising concerns over the “irrational and non-scientific use of convalescent plasma for Covid-19”. The letter addressed to Principal Scientific Advisor Dr Vijay Raghavan says, “We are writing to you as concerned clinicians, public health professionals …

What Widespread Recommendation of Remdesivir for COVID-19 and Its Shortage Teach Us
3 years, 7 months ago

What Widespread Recommendation of Remdesivir for COVID-19 and Its Shortage Teach Us

News 18  

Soon after the start of the second wave of COVID-19 pandemic in India, the images of people standing in long queues outside the chemist stores/pharmacies across India, were all over the newspapers. Though clinical trials have not found Remdesivir beneficial in COVID-19 treatment; however, clinicians in India and even the national COVID-19 task force and expert groups in India continue …

Remdesivir Not Magic Bullet, Does Not Reduce Covid-19 Mortality: AIIMS Chief Randeep Guleria
3 years, 8 months ago

Remdesivir Not Magic Bullet, Does Not Reduce Covid-19 Mortality: AIIMS Chief Randeep Guleria

News 18  

Amid a steep spike in COVID-19 cases leading to increased demand for medicines for treating coronavirus, top health experts in the government on Monday said anti-viral drug remdesivir is "not a magic bullet" and does not reduce mortality. Addressing the media, AIIMS Director Dr Randeep Guleria said remdesivir should only be given to patients hospitalised with moderate illness, who had …

No evidence of Remdesivir's effectiveness in treating Covid patients: WHO
3 years, 8 months ago

No evidence of Remdesivir's effectiveness in treating Covid patients: WHO

India Today  

Amid the surge in demand for antiviral drug Remdesivir, the World Health Organization has said that there is still no evidence to suggest that the drug is useful in treating hospitalised Covid-19 patients. WHO's Chief Scientist Dr Soumya Swaminathan and its Technical Lead on Covid, Dr Maria Van Kerkhove on Monday told India Today TV that results from five clinical …

Convalescent Plasma Strikes Out As COVID-19 Treatment
3 years, 9 months ago

Convalescent Plasma Strikes Out As COVID-19 Treatment

NPR  

Convalescent Plasma Strikes Out As COVID-19 Treatment Enlarge this image toggle caption Karen Ducey/Getty Images Karen Ducey/Getty Images More than half a million Americans have received an experimental treatment for COVID-19 called convalescent plasma. Sponsor Message She recalls thinking, "we have this new disease that didn't have any known therapies, and convalescent plasma has been used in new epidemic and …

Study shows Covid-19 evolved during treatment, convalescent plasma therapy patients had UK mutant
3 years, 10 months ago

Study shows Covid-19 evolved during treatment, convalescent plasma therapy patients had UK mutant

India Today  

A recent study has revealed that the dominant variant of the novel coronavirus or Covid-19 that emerged in patients after the convalescent plasma therapy possessed a mutation that is also present in the one first discovered in the UK. ".data reveal strong selection on SARS-CoV-2 during convalescent plasma therapy associated with the emergence of viral variants with evidence of reduced …

Worrying new coronavirus variants could be home grown as well as imported
3 years, 10 months ago

Worrying new coronavirus variants could be home grown as well as imported

CNN  

CNN — The 45-year-old patient had been sick with coronavirus for months. “This patient’s mutations include hallmarks of the new variants, like N501Y and 484K,” Li said. Then, as we saw these new variants emerging from the UK, from South Africa, from Brazil, we saw the same mutations.” The case, which Li and colleagues detailed late last year in a …

COVID-19 patients are being treated with drugs such as itolizumab even though there is insufficient evidence on their efficacy against the disease
4 years ago

COVID-19 patients are being treated with drugs such as itolizumab even though there is insufficient evidence on their efficacy against the disease

The Hindu  

THE COVID-19 caseload continues to rise in India, with State governments, including those of Delhi and the industrial hub Maharashtra, signalling that their States are experiencing new waves of the pandemic. It has been confirmed that during the clinical phase II trial for the drug itolizumab —which is manufactured and marketed by Biocon Biologics, a subsidiary of Biocon Limited, founded …

Coronavirus | ICMR warns against indiscriminate use of convalescent plasma therapy
4 years, 1 month ago

Coronavirus | ICMR warns against indiscriminate use of convalescent plasma therapy

The Hindu  

The Indian Council of Medical Research has warned against indiscriminate use of convalescent plasma therapy for treating COVID-19. On Wednesday, it released report of an open-label phase II multicentre randomised controlled trial conducted across 39 public and private hospitals on the use of CPT in management of cases with moderate infection. The report concluded that the therapy “did not lead …

Indiscriminate Use of Convalescent Plasma Therapy in Covid Patients Not Advisable, Warns ICMR
4 years, 1 month ago

Indiscriminate Use of Convalescent Plasma Therapy in Covid Patients Not Advisable, Warns ICMR

News 18  

The country's apex health research body, ICMR, has issued an advisory statingthat indiscriminate use of convalescent plasma therapy in coronavirus infected patients is not advisable. In an "Evidence Based Advisory to address Inappropriate Use of Convalescent Plasma in COVID-19 Patients", the Indian Council of Medical Research said that a potential donor for convalescent plasma should have sufficient concentration of antibody …

Indiscriminate Use of Plasma Therapy Not Advisable: ICMR
4 years, 1 month ago

Indiscriminate Use of Plasma Therapy Not Advisable: ICMR

The Quint  

Experts in India have long called out the lack of evidence to support this treatment. Speaking to FIT, Dr Sumit Ray, Senior consultant of Critical Care Medicine, Holy Family Hospital, said, “The theoretical benefit of plasma therapy is in helping boost immunity if not enough is developed in the patient. But, the problem with COVID-19 is not of an inadequate …

Dutch Covid medicine made from blood plasma ready for use
4 years, 1 month ago

Dutch Covid medicine made from blood plasma ready for use

NL Times  

Blood bank Sanquin and plasma producer Sanquin Plasma Products produced 4 thousand doses of Covid-19 antibody treatment made from the blood plasma of recovered patients. The plasma medicine will first go towards preventing coronavirus infections in people with weakened immune systems, such as cancer patients and people who have just undergone an organ transplant. Minister Hugo de Jonge of Public …

Treatment Protocols Being Reassessed 10 Months into Covid-19 Pandemic, Focus on Aspirin as Potential Drug
4 years, 1 month ago

Treatment Protocols Being Reassessed 10 Months into Covid-19 Pandemic, Focus on Aspirin as Potential Drug

News 18  

“From today, aspirin will be investigated in the world’s largest clinical trial of treatments for patients hospitalised with COVID-19. The Randomised Evaluation of COVid-19 therapy trial is taking place in 176 hospital sites across the UK, and has so far recruited over 16,000 patients,” read the RECOVERY Trial’s web information page on Aspirin. This is the newest entrant in the …

The plasma dead end?
4 years, 2 months ago

The plasma dead end?

India Today  

Since ILBS Hospital, in New Delhi, inaugurated its plasma bank in early July, requests have poured in ceaselessly. Many examples of adverse reactions and the inability of plasma treatment to reduce Covid mortality have been recorded in the ICMR’s PLACID trial too. As a result, the ICMR has announced the possibility of removing convalescent plasma therapy as one of the …

Plasma Therapy Doesn't Reduce COVID Mortality: ICMR Study in BMJ
4 years, 2 months ago

Plasma Therapy Doesn't Reduce COVID Mortality: ICMR Study in BMJ

The Quint  

In India, the treatment first made news in mid-April when a patient in Delhi received experimental plasma therapy and was weaned off from ventilator support. Delhi’s Max Hospital gave a 49-year-old male COVID-19 patient plasma treatment on compassionate grounds. In the experimental treatment, antibodies from the blood of patients who have recovered from coronavirus are given to those battling the …

’Plasma therapy has saved lives of many including mine’: Jain on ICMR’s decision
4 years, 2 months ago

’Plasma therapy has saved lives of many including mine’: Jain on ICMR’s decision

Live Mint  

Delhi health minister Satyender Jain on Wednesday said that plasma therapy treatment has saved lives of many from the novel coronavirus in the past months, after the Indian Council of Medical Research on Tuesday said that it considers removing it from Covid-19 national treatment protocol. "Lives of more than 2000 people, including mine, have been saved through plasma therapy, so …

Mumbai local trains to allow women travellers from today; Centre mulls removing plasma therapy as treatment
4 years, 2 months ago

Mumbai local trains to allow women travellers from today; Centre mulls removing plasma therapy as treatment

Firstpost  

Currently only those engaged in frontline duties and falling in the essential staff category of the Maharashtra government are allowed to travel in the local trains run by Central Railway and Western Railway As daily coronavirus cases in India dropped below 50,000 for the first time in nearly three months, Railway minister Piyush Goyal announced that women passengers will be …

ICMR may remove plasma therapy from Covid-19 treatment guidelines
4 years, 2 months ago

ICMR may remove plasma therapy from Covid-19 treatment guidelines

Live Mint  

New Delhi: The government is planning to delete convalescent plasma therapy from the national guidelines for covid-19 treatment after the Indian Council of Medical Research’s clinical trial showed that the therapy did not significantly benefit patients suffering from the disease, ICMR DG Balram Bhargava said on Tuesday. ICMR, which is the government’s apex bio-medical research agency, had conducted a 464 …

The Rise & Fall of Plasma Therapy as COVID-19 Treatment in India
4 years, 2 months ago

The Rise & Fall of Plasma Therapy as COVID-19 Treatment in India

The Quint  

On a daily basis, one gets at least two to three messages of desperate family members searching for a plasma donor for their loved ones battling COVID-19. Delhi set up a plasma bank in June to cater to the increasing demand of COVID-19 patients, with several states following the example. In June, the Union Health Ministry, in their clinical guidelines …

WHO trial results show remdesivir has little or no effect for covid-19 patients
4 years, 2 months ago

WHO trial results show remdesivir has little or no effect for covid-19 patients

Live Mint  

Interim results from the World Health Organization’s solidarity trial showed that Gilead Sciences Inc’s remdesivir showed little or no effect for covid-19 patients, a result which was significantly different from the positive results shown by Gilead’s own trial. “These remdesivir, hydroxychloroquine, lopinavir and interferon regimens appeared to have little or no effect on hospitalized covid-19 patients, as indicated by overall …

Coronavirus | Repurposed drugs did not cut down mortality, says WHO
4 years, 2 months ago

Coronavirus | Repurposed drugs did not cut down mortality, says WHO

The Hindu  

Interim results from the Solidarity Therapeutics Trial, coordinated by the World Health Organization, have indicated that remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon regimens appeared to have little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalised patients as per information released by the World Health Organisation. Speaking exclusively to The Hindu, about the outcome Prof. K …

DCGI Nod to Phase-1 Human Trials of 'Antisera' with Potential to Treat Covid-19
4 years, 2 months ago

DCGI Nod to Phase-1 Human Trials of 'Antisera' with Potential to Treat Covid-19

News 18  

The Drugs Controller General of India has given permission for conducting Phase-1 human clinical trial for an "antisera" that was developed by injecting inactivated SARS-CoV-2 in horses and can be a potential treatment for COVID-19, ICMR officials said on Tuesday. "With Biological E Limited we have developed an horse 'antisera' and we have just got clearance for conducting clinical trials …

Coronavirus | India far from herd immunity, says Health Minister
4 years, 2 months ago

Coronavirus | India far from herd immunity, says Health Minister

The Hindu  

Union Health Minister Harsh Vardhan on Sunday cautioned that the Indian Council of Medical Research’s COVID-19 first sero-survey should not create a sense of complacency in people with regard to the virus. Speaking in his social media interaction Sunday Samvaad-3, Mr. Vardhan said indications from the up-coming second sero survey “are that India is far from having achieved any kind …

Covid-19: Plasma therapy to start in eight north Bengal districts
4 years, 3 months ago

Covid-19: Plasma therapy to start in eight north Bengal districts

Hindustan Times  

The West Bengal government will start plasma therapy for coronavirus disease patients in eight districts in north Bengal next week. Indian Council of Medical Research has allowed convalescent plasma to be used for moderately ill Covid-19 patients. Convalescent plasma therapy involves extraction of plasma from the blood of Covid-19 patients four weeks after they have been cured of their viral …

SC Says Centre Approved Use of Remdesivir and Fabiparivir to Treat Coronavirus Patients
4 years, 3 months ago

SC Says Centre Approved Use of Remdesivir and Fabiparivir to Treat Coronavirus Patients

News 18  

The Supreme Court on Wednesday said there was an approval by the Central government on use of Remdesivir and Fabiparivir as medicines to treat COVID-19. The top court was hearing a plea seeking registration of an FIR by the CBI against ten Indian pharmaceutical firms for manufacturing and selling these two medicines for treating COVID-19 patients allegedly without valid licences. …

Delhi to Continue Plasma Therapy for Coronavirus Patients Despite ICMR Study Showing No Benefit
4 years, 3 months ago

Delhi to Continue Plasma Therapy for Coronavirus Patients Despite ICMR Study Showing No Benefit

News 18  

Covid-19 patients in national capital will continue to be treated with blood plasma donated by survivors of the novel coronavirus, Delhi’s health minister Satyendar Jain said on Thursday despite clinical trials not proving whether plasma therapy can help people fighting the infection. A trial conducted across 39 hospitals in India and spearheaded by the Indian Council of Medical Research found …

Coronavirus | Plasma therapy didn’t help COVID-19 patients: ICMR
4 years, 3 months ago

Coronavirus | Plasma therapy didn’t help COVID-19 patients: ICMR

The Hindu  

Convalescent plasma therapy failed to benefit coronavirus patients, the largest trial conducted across 39 hospitals in India and spearheaded by the Indian Council of Medical Research found. The trial spanning April-July enrolled 464 hospitalised patients with “moderate” COVID-19 and administered convalescent plasma — antibodies derived from plasma filtered from the blood of those who have recovered from COVID-19 — on …

Coronavirus: Plasma therapy not beneficial in reducing mortality, shows ICMR study
4 years, 3 months ago

Coronavirus: Plasma therapy not beneficial in reducing mortality, shows ICMR study

The Hindu  

Convalescent plasma therapy failed to benefit coronavirus patients, the largest trial conducted across 39 hospitals in India and spearheaded by the Indian Council of Medical Research found. The trial spanning April-July enrolled 464 hospitalised patients with “moderate” COVID-19 and administered convalescent plasma — antibodies derived from plasma filtered from the blood of those who have recovered from COVID-19 — on …

Plasma Therapy Ineffective in Reducing COVID Mortality: ICMR Study
4 years, 3 months ago

Plasma Therapy Ineffective in Reducing COVID Mortality: ICMR Study

The Quint  

This means that at best, plasma therapy is not getting at the crux of the problem. “Here you are giving plasma for a disease which is procoagulant or prone to causing clots.” Convalescent plasma was used in certain diseases where the immune response was poor or antibodies were not produced. So if there is already lung damage due to COVID, …

Convalescent plasma not proven for coronavirus, panel says
4 years, 3 months ago

Convalescent plasma not proven for coronavirus, panel says

CNN  

CNN — A National Institutes of Health panel said there’s no evidence backing the use of convalescent plasma to treat coronavirus patients and that doctors should not treat it as a standard of care until more study has been done. “Convalescent plasma should not be considered standard of care for the treatment of patients with COVID-19,” the committee, which evaluates …

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