Body mass index (BMI) plays significant role in progression of multiple sclerosis: Study
5 years, 11 months ago

Body mass index (BMI) plays significant role in progression of multiple sclerosis: Study

Hindustan Times  

A recent study has identified a link between high levels of blood lipids and worsening of disease in multiple sclerosis patients who are overweight or obese. “Our study identifies important correlations between ceramide levels, body mass index, and disease progression in MS patients,” said Patrizia Casaccia, lead author of the study. As part of the study, researchers found that overweight and obese individuals with MS have higher ceramide levels than people with the disease who are not overweight and also those individuals who are overweight or obese but otherwise in healthy conditions. In this study, however, we also detect higher ceramide levels in the blood of overweight and obese MS patients than we did in patients with normal body mass index, suggesting that overabundant lipids can be derived not only from damaged brain cells but also from excessive dietary intake of saturated fats,” Casaccia asserted. Researchers found that MS patients with high body mass indexes had higher ceramide levels and more circulating monocytes than were evident in healthy individuals with the same BMIs.

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