California doctor says arthritis drug improved coronavirus patients' symptoms within 72 hours
4 years, 8 months ago

California doctor says arthritis drug improved coronavirus patients' symptoms within 72 hours

Daily Mail  

Dr Imran Sharief, a pulmonologist from California, gave tocilizumab, a drug used to treat rheumatoid arthritis, to severely ill COVID-19 patients A California physician says a rheumatoid arthritis drug could be an effective treatment for coronavirus. Dr Imran Sharief, a pulmonologist based in Santa Ana, told Fox News that he treated COVID-19 patients on ventilators with tocilizumab, sold under the brand names RoAcemtra and Actemra, Within 72 hours, their conditions began to improve and, after five days, he was able to extubate patients and move them out of the ICU. Pictured: Tocilizumab Researchers believe the drug mitigates cytokine storms, which occur when the body doesn't just fight off the virus but also attacks its own cells and tissues. Pictured: US Army service members transport a patient to the ICU at the Javits New York Medical Station, April 18 He said that if certain critically ill patients are treated with the drug early, organ damage could be prevented.

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History of this topic

Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study
2 years, 10 months ago

Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study

Hindustan Times  

An anti-inflammatory drug normally used to treat rheumatoid arthritis reduces the risk of death when given to hospitalised patients with severe Covid-19, according to a study led by researchers at the University of Oxford. Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study The benefit of baricitinib is in addition to those of dexamethasone and tocilizumab, two other …

Govt Advises Covid Patients to Avoid Steroids, Says 'Go for TB Test If Cough Persists for Over 2-3 Weeks'
2 years, 11 months ago

Govt Advises Covid Patients to Avoid Steroids, Says 'Go for TB Test If Cough Persists for Over 2-3 Weeks'

News 18  

The Centre has advised people infected with Covid-19 to go for tests for tuberculosis and other conditions if cough persists for more than two-three weeks. “If cough persists for more than two-three weeks, one should opt for investigation for tuberculosis and other conditions,” the revised guidelines read and recommended emergency use authorization or off-label use of remdesivir in patients with …

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment
2 years, 11 months ago

India Cuts Use of Remdesivir, Tocilizumab, Multivitamins, Steroids in Covid-19 Treatment

News 18  

India has cut down on the use of the experimental drug Remdesivir and immunosuppressive drug Tocilizumab for the treatment of Covid-19. While it states that doctors can “consider Remdesivir for five days to treat hospitalised patients with Covid-19”, it also mentions that “no evidence of benefit for treatment more than five days”. Discouraging the overuse of steroids, the protocol for …

Utrecht researchers find new treatment for intubated Covid-19 patients
4 years, 1 month ago

Utrecht researchers find new treatment for intubated Covid-19 patients

NL Times  

Researchers found that existing medicine Tocilizumab, used for rheumatoid arthritis, can shorten the length of time seriously ill Covid-19 patients have to be intubated and in intensive care. Doctor and microbiologist at the Utrecht hospital Marc Bonten called it "really good news" for patients, speaking to ANP. "It is precisely for the group of seriously ill people in intensive care …

Timely treatment with tocilizumab likely to improve clinical outcomes in severe COVID-19 patients, finds study
4 years, 2 months ago

Timely treatment with tocilizumab likely to improve clinical outcomes in severe COVID-19 patients, finds study

Firstpost  

The drug is already approved and is used for the treatment of rheumatoid arthritis, an autoimmune disease that leads to joint inflammation and pain Patients with severe COVID-19 are likely to have short-term mortality rates between 35 percent to 62 percent, according to a study published in the journal JAMA Internal Medicine. A group of researchers at US’ Birmingham and …

Could we cure coronavirus?
4 years, 5 months ago

Could we cure coronavirus?

ABC  

In the quest to find life-saving COVID-19 treatments, scientists are trying everything from using the blood of coronavirus survivors to recycling old HIV drugs. All have shown promise, but this virus is also proving hard to outsmart: The century-old 'bag of blood' approach relying on altruistic people like Damian The century-old 'bag of blood' approach relying on altruistic people like …

Coronavirus | No evidence yet that itolizumab, tocilizumab reduces deaths: ICMR head
4 years, 5 months ago

Coronavirus | No evidence yet that itolizumab, tocilizumab reduces deaths: ICMR head

The Hindu  

There is yet no evidence from trials that itolizumab and tocilizumab, two drugs, one of which has been developed by Bengaluru-based Biocon Biologics, reduce death in severely ill coronavirus patients, Director-General of the ICMR Balram Bhargava said at a Health Ministry press briefing on Tuesday. Biocon’s COVID-19 drug tested on too few patients to reliably conclude on benefits, say experts …

COVID-19 treatments: Which drugs, therapies are proven to work, and which ones don’t?
4 years, 6 months ago

COVID-19 treatments: Which drugs, therapies are proven to work, and which ones don’t?

Firstpost  

We have made amazing progress in the treatment of COVID-19. Ritonavir increases the level of Lopinavir in the blood so the lopinavir/ritonavir combination was tested in a randomized controlled clinical trial for COVID-19. Steroids – yes for almost all COVID-19 patients When a synthetic steroid hormone, called dexamethasone, was given to patients with COVID-19 the drug decreased 28-day mortality by …

Health ministry recommends tocilizumab, HCQ, plasma therapy for patients in the moderate stage of COVID-19
4 years, 6 months ago

Health ministry recommends tocilizumab, HCQ, plasma therapy for patients in the moderate stage of COVID-19

Firstpost  

HCQ has demonstrated in-vitro activity against SARS-CoV-2 and shown to be clinically beneficial in several small single-centre studies with significant limitations. The Health Ministry on Saturday recommended the use of antiviral drug in the moderate stage of COVID-19 while backtracking from its earlier stance on hydroxychloroquine, saying the anti-malarial drug should be used in the early course of the disease …

Coronavirus | U.K. trial to test efficacy of five drugs
4 years, 7 months ago

Coronavirus | U.K. trial to test efficacy of five drugs

The Hindu  

With a range of approved drugs now being tested on COVID-19 patients, there is no clarity on which one will turn out to be more effective in treatment compared with the standard of hospital care that all patients receive. The recovery trial, coordinated by the Nuffield Department of Population Health at University of Oxford, will randomise patients to receive either …

Arthritis drug may improve coronavirus patients - but experts warn effects are far from proven
4 years, 8 months ago

Arthritis drug may improve coronavirus patients - but experts warn effects are far from proven

Daily Mail  

An arthritis drug may better the conditions of severely ill coronavirus patients, a new small study suggests. Researchers tested 29 Italian coronavirus patients with anakinra, an arthritis drug, and compared them to 16 control patients In the study, 72% showed improved respiratory health and reduced signs of cytokine storms, which occur when the body attacks not just the virus but …

Coronavirus update: Decade-old medicine emerges as hope for COVID-19 victims
4 years, 10 months ago

Coronavirus update: Decade-old medicine emerges as hope for COVID-19 victims

Live Mint  

China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide. China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with …

Coronavirus outbreak: Cocktail of flu, HIV drugs appears to help fight virus, say Thai doctors
4 years, 11 months ago

Coronavirus outbreak: Cocktail of flu, HIV drugs appears to help fight virus, say Thai doctors

India Today  

Thai doctors have seen success in treating severe cases of the new coronavirus with combination of medications for flu and HIV, with initial results showing vast improvement 48 hours after applying the treatment, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their …

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