ICMR considers developing vaccine against Nipah
1 year, 3 months ago

ICMR considers developing vaccine against Nipah

Hindustan Times  

The Indian Council of Medical Research is considering developing a vaccine against the Nipah virus, as part of a larger plan to develop a bouquet of essential vaccines. “Our biggest asset at the moment is that we have developed vaccines on diverse platforms such -- DNA vaccine, mRNA vaccine, adenoviral vector vaccine, protein subunit vaccine, and nasal vaccine -- and we can use these diverse platforms also to develop newer vaccines against diseases such as Nipah, which is required,” he added. “There will be hindrances in developing a vaccine against Nipah that we are well aware of which won’t be there in developing vaccines against a disease like dengue as it would have a large market. The US’ National Institutes of Health announced last year that it has launched early stage clinical trial of mRNA Nipah virus vaccine. “The need for a preventive Nipah virus vaccine is significant.” Nipah virus infection is a zoonotic disease that spreads between animals and people.

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History of this topic

ICMR ties up with IIL to develop jab against Zika virus
3 months, 1 week ago

ICMR ties up with IIL to develop jab against Zika virus

Hindustan Times  

The Indian Council of Medical Research has started work on a vaccine against the Zika virus, in collaboration with vaccine manufacturer Indian Immunologicals Limited, people familiar with the matter said. IIL has signed a memorandum of association with ICMR for the clinical development of the vaccine — the country’s first codon de-optimised live attenuated vaccine against Zika — and Phase …

Phase-3 clinical trial of India's first dengue vaccine begins at KIMS-Bhubaneswar
3 months, 2 weeks ago

Phase-3 clinical trial of India's first dengue vaccine begins at KIMS-Bhubaneswar

New Indian Express  

BHUBANESWAR: The phase-3 clinical trial for India's first Indigenous dengue vaccine, ‘DengiAll,’ commenced at the Kalinga Institute of Medical Sciences on Tuesday. This trial aims to evaluate the efficacy of the Indigenous tetravalent dengue vaccine developed by Panacea Biotec in collaboration with the Indian Council of Medical Research. The tetravalent dengue vaccine, originally developed by the National Institutes of Health, …

ICMR, Panacea Biotec begin first-ever phase 3 clinical trial of made-in-India dengue vaccine
4 months, 1 week ago

ICMR, Panacea Biotec begin first-ever phase 3 clinical trial of made-in-India dengue vaccine

New Indian Express  

NEW DELHI: In a significant announcement, the centre on Wednesday said that the first-ever Phase 3 clinical trial for a made-in-India dengue vaccine has been initiated. The Indian Council of Medical Research and Panacea Biotec have announced the initiation of this landmark trial, which will evaluate the efficacy of India’s indigenous tetravalent dengue vaccine, DengiAll, developed by Panacea Biotec. The …

Nipah virus: A recurring, deadly threat in India
5 months ago

Nipah virus: A recurring, deadly threat in India

Hindustan Times  

Health authorities in India face outbreaks of Nipah virus almost every other year. After a 14-year-old boy died of Nipah virus Sunday, July 21, 2024, in the southern Indian state of Kerala, authorities tried to stop a new outbreak — just a year after the last outbreak in 2023. Nipah virus is commonly found in fruit bats, which feed on …

Why the inability to identify the Nipah virus sources is a concern in Kerala
5 months ago

Why the inability to identify the Nipah virus sources is a concern in Kerala

Hindustan Times  

Kerala is on high alert after a 14-year-old boy in the Malappuram district was diagnosed with Nipah virus infection on Sunday. While initiating preventive protocols and steps to contain the virus in the reported area itself, health department officials are said to have zeroed in on a potential cause for the re-emergence of the Nipah virus. Some local doctors cite …

Oxford scientists launch first human vaccine trials for deadly Nipah virus
11 months, 1 week ago

Oxford scientists launch first human vaccine trials for deadly Nipah virus

The Hindu  

Scientists at the University of Oxford in the U.K. have launched first-in-human vaccine trials for the deadly Nipah virus which impacts many Asian countries, including India. "Nipah virus was first identified in 1998, and yet 25 years on the global health community still has no approved vaccines or treatments for this devastating disease," said the trial's Principal Investigator, Brian Angus, …

Human testing of first Nipah virus vaccine begins
11 months, 1 week ago

Human testing of first Nipah virus vaccine begins

India Today  

After successful preclinical trials of a vaccine candidate, called ChAdOx1 NiV, for the brain-swelling Nipah virus, it has entered the human testing phase. Conducted by the University of Oxford with 52 participants, the human trial will assess safety and immune response in individuals aged 18 to 55, a spokesperson for the University's Pandemic Sciences Institute told news agency Reuters. While …

The science behind Nipah vaccine: How ChAdOx1 NipahB vaccine works
11 months, 1 week ago

The science behind Nipah vaccine: How ChAdOx1 NipahB vaccine works

India Today  

In a major development toward combating the deadly Nipah virus, scientists have developed a vaccine candidate known as ChAdOx1 NiV, which has shown promising results in preclinical trials and has now entered human testing phases. The ChAdOx1 NiV vaccine uses a replication-deficient chimpanzee adenoviral vector, ChAdOx1, which has been engineered to express the NiV glycoprotein. When challenged with the lethal …

Nipah centre will take up pioneering research work, says Veena George
1 year, 1 month ago

Nipah centre will take up pioneering research work, says Veena George

The Hindu  

The Kerala One Health Centre for Nipah Research will be developed to take up pioneering research that will serve as a model for the world, Health Minister Veena George has said. Ms. George said that with Kerala successfully battling recurring cases of the infection, it had unique experiences in containment steps. Ms. George said the centre would also have a …

No new cases of Nipah virus detected in India since September: WHO
1 year, 2 months ago

No new cases of Nipah virus detected in India since September: WHO

Hindustan Times  

The World Health Organization on Tuesday said that no new cases of the brain-damaging Nipah virus were detected in India since September 15, after an outbreak in early September led to two deaths. The Kozhikode district administration lifts restrictions after no fresh cases of Nipah virus were reported in Kerala. Between September 12 and 15, the Union health ministry reported …

No new Nipah virus cases in India since September 15, says WHO
1 year, 2 months ago

No new Nipah virus cases in India since September 15, says WHO

Live Mint  

The World Health Organization on Tuesday said that no new cases of Nipah virus have been detected in India since September 15. From September 12 to 15, India's health ministry reported six laboratory-confirmed Nipah virus cases, including two deaths, in Kozhikode district in the southern state of Kerala. Since September 12, 387 samples have been tested, of which six cases …

WHO says no new cases of Nipah virus detected since Sept 15
1 year, 2 months ago

WHO says no new cases of Nipah virus detected since Sept 15

Firstpost  

In its sixth outbreak in the country since 2001 this year, the virus, known for its 70% mortality rate, has claimed two lives out of the six who were infected in a span of few days in September, sending the Kerala government scrambling to contain the spread No fresh cases of the deadly Nipah virus have been detected since September …

Lessons from Nipah outbreak in Kerala
1 year, 2 months ago

Lessons from Nipah outbreak in Kerala

Hindustan Times  

The Nipah Virus infection reported from Kozhikode, Kerala, coming in the aftermath of the Covid-19 pandemic, has attracted worldwide attention. The World Organisation for Animal Health observed that human cases have occurred sporadically in Bangladesh and India since 2003 without apparent related domestic animal disease outbreaks, suggesting possible human-to-human transmission. Covid-19 prompted the Prime Minister’s Science, Technology, and Innovation Advisory …

Nipah has around 70% mortality rate, Covid had 3%: ICMR
1 year, 3 months ago

Nipah has around 70% mortality rate, Covid had 3%: ICMR

Live Mint  

The mortality rate of the Nipah virus is much higher than Covid-19 viral disease, said ICMR DG Dr Rajeev Bahl on Friday. According to the Indian Council of Medical Research, the mortality rate of Nipah is around 60% as compared to that of Covid which was nearly 3% in the country. Rajeev Bahl emphasized that all the current cases of …

Nipah: Centre to procure 20 more doses of monoclonal antibody from Australia
1 year, 3 months ago

Nipah: Centre to procure 20 more doses of monoclonal antibody from Australia

Deccan Chronicle  

Kozhikode/New Delhi: A fresh case of Nipah virus was confirmed in Kozhikode, where two people were killed by the brain-damaging virus recently, the Kerala government said on Friday. State Health Minister Veena George said a 39-year-old man tested positive for the virus, which was transmitted to him through direct contact with an infected person who died on August 30. George …

To tackle Nipah, India to procure monoclonal antibody from Australia, says ICMR
1 year, 3 months ago

To tackle Nipah, India to procure monoclonal antibody from Australia, says ICMR

Hindustan Times  

India is in the process of procuring at least 20 doses of monoclonal antibody from Australia to treat patients infected with the Nipah virus, Indian Council of Medical Research director general Rajiv Bahl said on Friday. “We got some doses of monoclonal antibody from the University of Queensland, Australia, in 2018 when there was an outbreak of the disease. The …

'Antibody Use Not Approved, But...': ICMR on Treatment for Nipah Virus Outbreak
1 year, 3 months ago

'Antibody Use Not Approved, But...': ICMR on Treatment for Nipah Virus Outbreak

The Quint  

Dr Rajiv Bahl explained that the monoclonal antibody treatment was developed in the US and the technology for it was transferred to the University of Queensland in Australia. This is where India acquired a limited number of doses in 2018 when the first Nipah virus outbreak hit Kerala. "In the case of viral infections, monoclonal antibodies are the only 'anti-viral …

India to procure 20 more doses of monoclonal antibody from Australia for Nipah treatment: ICMR chief
1 year, 3 months ago

India to procure 20 more doses of monoclonal antibody from Australia for Nipah treatment: ICMR chief

The Hindu  

India will procure 20 more doses of monoclonal antibody for the treatment of Nipah virus infection from Australia, ICMR Director-General Rajeev Bahl said on Friday. Mr. Bahl also said mortality among the infected is very high in the case of Nipah virus compared to the mortality of COVID-19, which was 2-3%. It always happens in the rainy season.” He said …

Nipah Virus In India Mortality Rate 40-70 Percent ICMR DG Rajiv Bahl On Precautions Monoclonal Antibody Doses Nipah Virus Kerala
1 year, 3 months ago

Nipah Virus In India Mortality Rate 40-70 Percent ICMR DG Rajiv Bahl On Precautions Monoclonal Antibody Doses Nipah Virus Kerala

ABP News  

In the face of the ongoing Nipah virus threat, Dr. Rajiv Bahl, the Director-General of the Indian Council of Medical Research, has emphasised a series of precautionary measures aimed at containing the virus's spread. Dr. Bahl notes a stark contrast between Nipah and COVID-19, with the former exhibiting a mortality rate ranging between 40% and 70%, far surpassing the relatively …

Nipah virus outbreak | India reaches out to Australia for monoclonal antibody doses
1 year, 3 months ago

Nipah virus outbreak | India reaches out to Australia for monoclonal antibody doses

The Hindu  

India has reached out to Australia seeking to restock monoclonal antibody doses to combat the Nipah virus and is expecting 20 more doses soon, Indian Council of Medical Research head Dr. Rajiv Bahl said on Friday. “The mortality among the infected is very high in Nipah — between 40% and 70% — compared to the mortality in COVID, which was …

Nipah virus outbreak in India: What do we know so far?
1 year, 3 months ago

Nipah virus outbreak in India: What do we know so far?

Hindustan Times  

Authorities in India are scrambling to contain a rare outbreak of Nipah, a virus spread from animals to humans that causes deadly fever with a high mortality rate. Health workers collect blood samples from goats in the neighborhood for testing after a 12-year-old boy died of the Nipah virus in Kozhikode, Kerala. The first Nipah outbreak was recorded in 1998 …

Nipah Virus Updates: Educational institutions in Kozhikode shut till Sep 24
1 year, 3 months ago

Nipah Virus Updates: Educational institutions in Kozhikode shut till Sep 24

Hindustan Times  

With six confirmed cases of Nipah virus, Kerala has stepped up control measures to contain the deadly outbreak. Addressing a press conference the ICMR DG said on Friday that the mortality rate is high in Nipah virus cases compared to Covid cases. A five-member central team comprising experts from the National Centre for Disease Control, RML Hospital and NIMHANS has …

Nipah Virus's mortality is higher compared to Covid infection, says ICMR
1 year, 3 months ago

Nipah Virus's mortality is higher compared to Covid infection, says ICMR

India TV News  

In a press conference conducted by the Indian Council of Medical Research, Director General Rajeev Bahl said that the Nipah virus' cases mortality rate is higher in comparison to Covid cases. The Nipah virus mortality rate is 40-70% as the Covid virus' is 2-3%. The Director General Rajeev Bahl said that India will be procuring 20 more doses of monoclonal …

Mortality rate way higher for Nipah virus than coronavirus, warns government panel
1 year, 3 months ago

Mortality rate way higher for Nipah virus than coronavirus, warns government panel

India Today  

The Director General of the Indian Council of Medical Research Rajeev Bahl on Friday warned that the mortality rate in Nipah virus infection cases is very high compared to the Covid-19 infection. The mortality rate in Nipah virus cases is between 40 and 70 per cent, as compared to the mortality in Covid, which was 2-3 per cent, he said. …

Nipah virus outbreak: Kerala gets antibody, mobile lab to combat the virus
1 year, 3 months ago

Nipah virus outbreak: Kerala gets antibody, mobile lab to combat the virus

Live Mint  

The Indian Council of Medical Research Thursday delivered the monoclonal antibody to Kozhikode requested by Kerala to combat the Nipah outbreak in the district, PTI reported. The report said a five-member central team comprising experts from the National Centre for Disease Control, RML Hospital and NIMHANS has been stationed in Kerala to take stock of the situation and assist the …

Nipah: NIV teams to reach Kerala, virus is Bangladesh variant, says health minister
1 year, 3 months ago

Nipah: NIV teams to reach Kerala, virus is Bangladesh variant, says health minister

Deccan Chronicle  

Thiruvananthapuram: Teams from National Institute of Virology, Pune would arrive in Kerala during the day to set up a mobile lab at Kozhikode Medical College to test for Nipah and carry out survey of bats, the state government said in the assembly on Wednesday. Responding to a query regarding the Nipah infection in the assembly, State Health Minister Veena George …

Dengue vaccine: India moves closer to getting its first indigenous vaccine
1 year, 7 months ago

Dengue vaccine: India moves closer to getting its first indigenous vaccine

The Hindu  

Moving closer to being able to develop the country’s first vaccine against dengue, drug-makers Serum Institute of India and Panacea Biotec have applied to the Indian Council of Medical Research’s call for ‘Expression of Interest’ for collaborative Phase-III clinical trials for indigenous manufacturers. Phase-III clinical trial is being done for evaluation of efficacy, along with safety and immunogenicity of tetravalent …

Defanging Dengue: India Moving A Step Closer in Achieving Its First Vaccine for Dreaded Disease
2 years, 7 months ago

Defanging Dengue: India Moving A Step Closer in Achieving Its First Vaccine for Dreaded Disease

News 18  

The country’s first vaccine for dengue is now getting a step closer, as the Indian Council of Medical Research is planning to submit the clinical trial protocol to the nation’s drug regulator by June, News18.com has learnt. “Trials may start by October this year.” Role of ICMR in dengue vaccine project According to the expression of interest floated by ICMR, …

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak
3 years, 3 months ago

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak

NPR  

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak Enlarge this image toggle caption C.K. "It's really difficult to establish the cause of the boy's illness," says Dr. Thekkumkara Surendran Anish, associate professor of community medicine at the Government Medical College in Thiruvananthapuram. "We have a very clear understanding of how Nipah virus moves …

Nipah amidst a pandemic
3 years, 3 months ago

Nipah amidst a pandemic

The Hindu  

India is far from being anywhere near the finish line with regard to the coronavirus pandemic, even as fears of a Nipah virus outbreak have surfaced in Kerala with one confirmed death in Kozhikode. Outbreaks fanned by exotic viruses are not foreign to India: a glance at the weekly reports compiled by the Integrated Disease Surveillance Programme shows the diversity …

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease
3 years, 3 months ago

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease

Firstpost  

Nipah virus or, which was first identified during an outbreak in Kampung Sungai Nipah, Malaysia in 1998, is primarily a zoonotic disease carried by fruit bats of the Pteropodidae family Indian state of Kerala, which has seen a previous outbreak of Nipah virus in 2018 and stray cases going back to as far as 2001, has again reported a case …

What 2020 Gave Science: Medical Advances and Learnings from COVID
4 years ago

What 2020 Gave Science: Medical Advances and Learnings from COVID

The Quint  

The vaccines developed by Pfizer and Moderna - both use a technology that has never been used to create a vaccine so far. It involves using genetic material from the virus called mRNA, short for messenger RNA, which directs the body’s cells to stimulate the immune system. India’s first indigenous mRNA vaccine candidate, developed by Pune-based Gennova Biopharmaceuticals, has also …

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