Scientists in China are losing touch with patients of gene editing trials: Report
6 years, 2 months ago

Scientists in China are losing touch with patients of gene editing trials: Report

Firstpost  

China has asked hospitals, universities to submit reports on all gene-editing trials since 2013. The technology that powered this boost, a tool called CRISPR-Cas 9 to edit DNA inside living cells, has come under fire from a recent controversy from one such researcher, He Jiankui, whose study led to the birth of twin girls “Lulu and Nana”, who Jiankui claims were given immunity to HIV from having their genes edited. Now, a new Wall Street Journal report claims that another Chinese startup ‘Anhui Kedgene Biotechnology’ has lost touch with at least some of the patients in their gene-editing trials. China is now also asking hospitals and universities to submit thorough reports on all human gene-editing trials conducted since 2013, according to a South China Morning Post report. Jiankui who claimed to have produced the world’s first gene-edited babies works at the Southern University of Science and Technology in Shenzhen, China, and says that he used CRISPR gene-editing technology to alter the DNA in several human embryos.

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History of this topic

The controversial scientist He Jiankui hasn’t given up on gene-edited babies
1 month ago

The controversial scientist He Jiankui hasn’t given up on gene-edited babies

The Economist  

T he world was shocked in 2018 when He Jiankui, a Chinese biophysicist, announced that he had helped to produce two girls whose genetic code he had edited when they had been embryos. Scientists around the world condemned the work as wildly premature and possibly dangerous—the Chinese authorities agreed and Dr He was imprisoned for three years. And he still …

Ethical guideline issued for genome editing
8 months, 2 weeks ago

Ethical guideline issued for genome editing

China Daily  

China has issued a set of ethical rules on human genome editing, reiterating a strict ban on altering germ cells and embryos and clarifying standard ethical practices for gene editing research. "At present, any clinical research involving germline genome editing is irresponsible and not permitted," it said. Regarding clinical research involving genome editing of somatic cells — which are cells …

Guideline sets ethical rules for human genome editing research
8 months, 2 weeks ago

Guideline sets ethical rules for human genome editing research

China Daily  

China on Wednesday released a guideline that lays out a set of ethical rules for human genome editing research. Regarding clinical research involving genome editing of somatic cells — which are cells in the body other than sperm and egg cells, it said that such research should be aimed at preventing or treating diseases and should be carried out after …

Disgraced Chinese scientist He Jiankui who was jailed in 2019 for genetically editing human babies is back in the lab - and claims he's 'proud' of his past work
11 months, 3 weeks ago

Disgraced Chinese scientist He Jiankui who was jailed in 2019 for genetically editing human babies is back in the lab - and claims he's 'proud' of his past work

Daily Mail  

A disgraced Chinese scientist who was jailed for genetically editing human babies reveals he has returned to genetic research. He Jiankui has announced he has returned to the lab after being jailed for genetically editing human babies Dr He says that he intends to develop gene editing techniques for the treatment of rare diseases such as Duchenne muscular dystrophy and …

Chinese court sentences 'gene-editing' scientist to three years in prison
5 years, 2 months ago

Chinese court sentences 'gene-editing' scientist to three years in prison

The Hindu  

A Chinese court sentenced the scientist who created the world's first “gene-edited” babies to three years in prison on December 30, according to the official Xinhua media. The editing process, which he calls gene surgery, “worked safely as intended” and the girls are “as healthy as any other babies”, he said in one video. He did not provide any written …

The World Health Organization Says No More Gene-Edited Babies
55 years, 2 months ago

The World Health Organization Says No More Gene-Edited Babies

Wired  

The world’s largest public health authority has weighed in with the most authoritative statement yet on the use of Crispr to alter the DNA of human babies. Eight months after a rogue Chinese scientist revealed he had secretly created the world’s first gene-edited children, the World Health Organization is asking countries to put a stop to any experiments that would …

Scientists asked disgraced Chinese scientist He Jiankui for help gene-editing human embryos
5 years, 9 months ago

Scientists asked disgraced Chinese scientist He Jiankui for help gene-editing human embryos

Daily Mail  

A fertility clinic in Dubai asked disgraced scientist He Jiankui for help in controversial experiments modifying the genes of human embryos. Jennifer Doudna, a University of California, Berkeley, co-inventor of the CRISPR gene-editing tool that He Jiankui used, said that she has heard of others who want to edit embryos William Hurlbut of Stanford University speaks to reporters during the …

China draws up tighter rules on human gene and embryo trials
5 years, 11 months ago

China draws up tighter rules on human gene and embryo trials

The Hindu  

China’s top legislature will consider tougher rules on research involving human genes and embryos, the first such move since a Chinese scientist sparked controversy last year by announcing he had made the world’s first “gene-edited” babies. Under the draft laws sent to China’s legislature for review on Saturday, medical and human trials would face closer scrutiny and stricter requirements, such …

Chinese scientists defend implanting human gene into monkeys’ brains
5 years, 11 months ago

Chinese scientists defend implanting human gene into monkeys’ brains

CNN  

Hong Kong CNN — A Chinese researcher who sparked improved cognitive function in monkeys by implanting human genes into their brains has defended his experiment, which has divided the scientific community. In Su’s 2019 study, 11 rhesus monkeys were successfully implanted with copies of the human MCPH1 gene, an important marker for “brain development and brain evolution.” Analysis of the …

Chinese scientist behind gene-edited baby study gets fired for illegal actions
6 years, 2 months ago

Chinese scientist behind gene-edited baby study gets fired for illegal actions

Firstpost  

Experts expressed their hope that the report was just the beginning, & more action would be taken. A Chinese scientist who created what he said were the world’s first “gene-edited” babies evaded oversight and broke ethical boundaries in a quest for fame and fortune, state media said on Monday, as his former university said he had been fired. He had …

Gene-edited babies were illegal, say Chinese authorities
6 years, 2 months ago

Gene-edited babies were illegal, say Chinese authorities

CNN  

CNN — Authorities in China say experiments which led to the birth of the world’s first gene-edited babies broke the country’s laws, state-run Xinhua news reported Monday. On Monday, investigators from Guangdong Province Health Commission said that “the case has been initially identified as an explicitly state-banned human embryo-editing activity for reproductive purposes conducted by He Jiankui,” Xinhua reported. The …

Gene-edited babies: Chinese scientist was told ‘not to proceed’
6 years, 2 months ago

Gene-edited babies: Chinese scientist was told ‘not to proceed’

CNN  

CNN — As 2018 drew to a close, one scientist unveiled research that entered a new era of science. Everyone he talked to – which was not many people – had said “don’t go there,” “don’t do it,” explained Robin Lovell-Badge of the UK research facility the Francis Crick Institute, who organized the scientific summit in Hong Kong during which …

Chinese scientists who edited human genes have lost touch with the patients whose DNA they tweaked
6 years, 2 months ago

Chinese scientists who edited human genes have lost touch with the patients whose DNA they tweaked

Daily Mail  

Chinese scientists who edited human genes have lost touch with the patients they treated, according to a new Wall Street Journal report. The scientific community is concerned about ethics and unintended consequences just weeks after another Chinese scientist claimed he modified the DNA of twin girls to make them resistant to AIDS - and that he is working on another …

Experts urge oversight of experiments
6 years, 3 months ago

Experts urge oversight of experiments

China Daily  

Genetics research, conceptual artwork. CHINA DAILY Scientists, researchers say gene editing project was unnecessary, irresponsible The world urgently needs better international oversight of genome editing in human embryos, and to clarify the boundaries for related research, according to an editorial published in the journal Science on Friday. "To maintain the public's trust that someday genome editing will be able to …

Experts urge oversight of experiments
6 years, 3 months ago

Experts urge oversight of experiments

China Daily  

Genetics research, conceptual artwork. CHINA DAILY Scientists, researchers say gene editing project was unnecessary, irresponsible The world urgently needs better international oversight of genome editing in human embryos, and to clarify the boundaries for related research, according to an editorial published in the journal Science on Friday. "To maintain the public's trust that someday genome editing will be able to …

Gene editing: WHO panel to address complex issues
6 years, 3 months ago

Gene editing: WHO panel to address complex issues

CNN  

CNN — The World Health Organization is creating a working group to study gene editing and the complex ethical, social and safety issues the procedure raises. Dr. Tedros Adhanom Ghebreyesus, WHO’s director-general, discussed the challenges gene editing technologies bring and the creation of an expert panel during a press conference Monday, where he warned of the potential for “unintended consequences.” …

Chinese gene-editing scientist is missing amid rumours of arrest
6 years, 3 months ago

Chinese gene-editing scientist is missing amid rumours of arrest

Daily Mail  

The whereabouts of Chinese scientist He Jiankui, who claims to have created the world's first gene-edited babies, remain unknown amid rumours that he has been arrested. Reports claimed He was placed under effective house arrest in Shenzhen after making an appearance at the Second International Summit on Human Genome Editing in Hong Kong last Wednesday. His whereabouts remain unknown after …

Gene editing experts discuss whether controversy is rushing the still-young technology
6 years, 3 months ago

Gene editing experts discuss whether controversy is rushing the still-young technology

Firstpost  

A Chinese scientist’s stunning claim he has pioneered the world’s first genetically modified baby has suddenly made the eternal debate over ethics and emerging scientific capabilities pressing and real. “It’s obvious that everything that is technically feasible is not ethically desirable,” said Cynthia Fleury, a member of the French Ethics Committee. “Trying to rush the technology” The concern of the …

‘Extremely abominable’: Chinese gene-editing scientist faces law
6 years, 3 months ago

‘Extremely abominable’: Chinese gene-editing scientist faces law

Al Jazeera  

China condemns the work of He Jiankui as institutions distance themselves from the academic who gene-edited twin girls. Xi said genetically engineering the DNA of twin girls so they would not develop HIV, breached scientific ethics, adding that gene-editing of human embryos for reproduction purposes was “explicitly banned” in China. China’s National Health Commission said He’s activities would be investigated …

China suspends He Jiankui’s research activities
6 years, 3 months ago

China suspends He Jiankui’s research activities

CNN  

Hong Kong CNN — China has suspended the research activities of the scientists who claimed to have created the world’s first gene-edited babies, state-run Xinhua news reported Thursday. “The gene-edited twins matter reported by the media has brazenly violated Chinese laws and regulations and breached the science ethics bottom line, which is both shocking and unacceptable,” said Xu Nanping, vice …

Chinese scientist says a second pregnancy is underway
6 years, 3 months ago

Chinese scientist says a second pregnancy is underway

Daily Mail  

A controversial Chinese scientist who this week claimed to have created the world's first gene-edited babies now says a second pregnancy is underway. Dr He Jiankui revealed the possible pregnancy while making his first public comments about his scandal-hit work at an international genome editing conference in Hong Kong One British scientist, who described the experiment as 'monstrous', said the …

Genetics Summit waits for Chinese baby-editing researcher to take the stage
6 years, 3 months ago

Genetics Summit waits for Chinese baby-editing researcher to take the stage

Firstpost  

This is a great blow to China’s reputation & development of biomedical research: Chinese scientists. ‘Immediate investigation’ Qiu Renzong, formerly the vice president of the Chinese Ministry of Health’s ethics committee, told reporters at the gene editing conference that lax regulations in China mean that scientists who break the rules often face no punishment, and think of the ministry as …

China baby gene-editing scientist defends his research, raises possibility of third embryo
6 years, 3 months ago

China baby gene-editing scientist defends his research, raises possibility of third embryo

CNN  

Hong Kong CNN — The Chinese scientist who sparked an international outcry after alleging to have helped create the world’s first genetically edited babies has raised the possibility of a third child being born, after announcing that a separate woman was pregnant at an early stage with a modified embryo. He said his research has been submitted to a scientific …

Chinese scientist’s risky experiment with gene-editing babies (opinion)
6 years, 3 months ago

Chinese scientist’s risky experiment with gene-editing babies (opinion)

CNN  

Editor’s Note: Ford Vox is a physician specializing in rehabilitation medicine. But the CRISPR technique isn’t perfect, and in every few hundred cases, in what is referred to as “off-target events,” it can edit the wrong portion of DNA, potentially creating unwanted mutations. Rice’s spokesperson told me in an email that “this work as described in press reports, violates scientific …

Facing Backlash, Chinese Scientist Defends Gene-Editing Research On Babies
6 years, 3 months ago

Facing Backlash, Chinese Scientist Defends Gene-Editing Research On Babies

NPR  

Facing Backlash, Chinese Scientist Defends Gene-Editing Research On Babies Enlarge this image toggle caption Kin Cheung/AP Kin Cheung/AP Updated at 6:15 a.m. Enlarge this image toggle caption Kin Cheung/AP Kin Cheung/AP She spoke after Harvard Medical School Dean George Daley alluded to He's claims as "missteps" that he worried might set back a highly promising field of research. "Just because …

Inventor of CRISPR calls for a global moratorium on gene-edited embryos, humans
6 years, 3 months ago

Inventor of CRISPR calls for a global moratorium on gene-edited embryos, humans

Firstpost  

The risks of such an experiment are still far greater than its benefits, Zhang said in a statement. A Harvard and MIT member, renowned genetic research Feng Zhang made the statement after a Chinese researcher claimed having helped create the world’s first babies with modified genes using CRISPR. The researcher claiming to have contributed to the success of the gene-editing …

Scientists, officials in China abhor gene editing that geneticist claims
6 years, 3 months ago

Scientists, officials in China abhor gene editing that geneticist claims

Live Mint  

Beijing/Shanghai: Chinese officials and scientists denounced on Tuesday the claims of a geneticist who said he had created the first gene-edited babies, and a hospital linked to his research suggested its ethical approval had been forged. China’s Genetics Society and the Chinese Society for Stem Cell Research said in a statement He had acted as an “individual” and his work …

World's first CRISPR gene-edited babies claimed by Chinese researcher as success
6 years, 3 months ago

World's first CRISPR gene-edited babies claimed by Chinese researcher as success

Firstpost  

Society will decide what to do next in terms of allowing or forbidding such science: Researcher. It’s “unconscionable … an experiment on human beings that is not morally or ethically defensible,” said Dr Kiran Musunuru, a University of Pennsylvania gene editing expert and editor of a genetics journal. It’s a big deal.” However, one famed geneticist, Harvard University’s George Church, …

Gene-edited baby claim sparks outrage
6 years, 3 months ago

Gene-edited baby claim sparks outrage

The Hindu  

More than 100 scientists, most of them in China, have condemned as “crazy” and unethical a geneticist's claim that he altered the genes of twin girls born this month to create the first gene-edited babies. China's National Health Commission said on Monday it was ”highly concerned” and had ordered provincial health officials “to immediately investigate and clarify the matter”. The …

Chinese academic claims to have gene-edited twins
6 years, 3 months ago

Chinese academic claims to have gene-edited twins

The Hindu  

Chinese health and medical ethics authorities started an investigation on Monday into claims by a scientist who released videos on YouTube, saying he had altered the genes of twins born earlier this month, creating the first gene edited babies. The editing process, which he calls gene surgery, “worked safely as intended” and the girls are “as healthy as any other …

China orders an inquiry into the 'world's first gene-edited babies'
6 years, 3 months ago

China orders an inquiry into the 'world's first gene-edited babies'

Daily Mail  

More than 100 scientists, most of them in China, have condemned a geneticist's claim that he altered the genes of twin girls born this month as 'crazy' and unethical. A US scientist said he took part in the work in China, but this kind of gene editing is banned in the United States due to risks that altered DNA will …

China orders probe into first ‘gene-edited babies’
6 years, 3 months ago

China orders probe into first ‘gene-edited babies’

Al Jazeera  

Scientists denounce claims by Chinese geneticist as concerns are raised about its safety and ethics. We still might have a glimmer of hope to close it before it's too late by Scientists say in an open letter The government’s medical ethics committee in Shenzhen said it was investigating the case, as was the Guangdong provincial health commission, according to Southern …

Chinese researcher claims first gene-edited babies
6 years, 3 months ago

Chinese researcher claims first gene-edited babies

Associated Press  

HONG KONG — A Chinese researcher claims that he helped make the world’s first genetically edited babies — twin girls born this month whose DNA he said he altered with a powerful new tool capable of rewriting the very blueprint of life. It’s a big deal.” However, one famed geneticist, Harvard University’s George Church, defended attempting gene editing for HIV, …

Chinese scientist claims world’s first gene-edited babies; hospital casts doubt
6 years, 4 months ago

Chinese scientist claims world’s first gene-edited babies; hospital casts doubt

CNN  

Hong Kong CNN — The Chinese government has ordered an “immediate investigation” into the alleged delivery of the world’s first genetically edited babies, as experts worldwide voiced outrage at such use of the technology. But in a statement posted Tuesday morning, China’s National Health Commission said that it had “immediately requested the Guangdong Provincial Health Commission to seriously investigate and …

Doctors In China Lead Race To Treat Cancer By Editing Genes
7 years, 1 month ago

Doctors In China Lead Race To Treat Cancer By Editing Genes

NPR  

Doctors In China Lead Race To Treat Cancer By Editing Genes Enlarge this image toggle caption Yuhan Xu/NPR Yuhan Xu/NPR Shaorong Deng is sitting up in bed at the Hangzhou Cancer Hospital waiting for his doctor. "This is the T-cell infusion," says Dr. Shixiu Wu, who's president of the cancer hospital in Hangzhou, a little over 100 miles southwest of …

WHAT IS CRISPR-CAS9?
7 years, 3 months ago

WHAT IS CRISPR-CAS9?

Daily Mail  

The approach has been used previously to edit the HBB gene responsible for a condition called β-thalassaemia. Get ready for genetically engineered 'super chocolate': Scientists use gene editing tools to make cacao trees resistant to disease Gene-editing tool CRISPR-Cas9 could help breed cacao trees that exhibit desirable traits such as enhanced resistance to diseases, a Penn. Revolutionary gene-editing tool CRISPR …

Team pulls its paper on gene editing
7 years, 7 months ago

Team pulls its paper on gene editing

China Daily  

Chinese biologists to conduct more research at another lab A biological research team from China said on Thursday it has withdrawn a controversial paper on a new gene-editing technique and will carry out further research at a third-party laboratory. The team, led by Han Chunyu of Hebei University of Science and Technology, published the paper in May last year in …

Team pulls its paper on gene editing
7 years, 7 months ago

Team pulls its paper on gene editing

China Daily  

Chinese biologists to conduct more research at another lab A biological research team from China said on Thursday it has withdrawn a controversial paper on a new gene-editing technique and will carry out further research at a third-party laboratory. The team, led by Han Chunyu of Hebei University of Science and Technology, published the paper in May last year in …

Scientists edit disease-causing gene mutation in human embryos
7 years, 7 months ago

Scientists edit disease-causing gene mutation in human embryos

CNN  

Story highlights In first-of-its-kind study, scientists describe correcting a gene mutation tied to genetic heart conditions The researchers say they could face political barriers when it comes to further studies CNN — Scientists are getting one step closer to snipping inherited genetic diseases out of human offspring using a gene-editing technique called CRISPR. For the first time, scientists said, they …

Report: Scientists edit human embryos for first time in US
7 years, 7 months ago

Report: Scientists edit human embryos for first time in US

CNN  

Story highlights A first in the US, scientists reportedly edit the genes of human embryos using CRISPR Yet the research hasn't been published and researchers remain tight-lipped CNN — America reportedly has moved ahead in a controversial race to tinker with human DNA – but the scientific feat is shrouded in unanswered questions. “I’m not surprised that they were looking …

Chinese scientist participates in human gene editing committee
8 years, 1 month ago

Chinese scientist participates in human gene editing committee

China Daily  

Chinese scientist participates in human gene editing committee Xinhua | Updated: 2017-02-16 17:18 BEIJING -- A Chinese scientist has participated in making recommendations for human gene editing that cover basic laboratory research, and somatic and germline genome editing, according to the Chinese Academy of Sciences. The report titled "Human Gene Editing: Science, Ethics, and Governance," suggests using "existing regulatory processes …

Chinese scientist participates in human gene editing committee
8 years, 1 month ago

Chinese scientist participates in human gene editing committee

China Daily  

Chinese scientist participates in human gene editing committee Xinhua | Updated: 2017-02-16 17:18 BEIJING -- A Chinese scientist has participated in making recommendations for human gene editing that cover basic laboratory research, and somatic and germline genome editing, according to the Chinese Academy of Sciences. The report titled "Human Gene Editing: Science, Ethics, and Governance," suggests using "existing regulatory processes …

To prevent serious medical conditions, scientists should be able to edit people’s DNA, panel says
8 years, 1 month ago

To prevent serious medical conditions, scientists should be able to edit people’s DNA, panel says

LA Times  

Scientists should be allowed to alter a person’s DNA in ways that will be passed on to future generations, but only to prevent serious and strongly heritable diseases, according to a new report from the National Academy of Sciences and the National Academy of Medicine. As such, the National Academies’ report acknowledges that changing heritable DNA in eggs, sperm and …

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial
8 years, 4 months ago

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial

Live Mint  

New Delhi: Close to a month ago, a team led by oncologist Lu You at Sichuan University’s West China Hospital in Chengdu injected a patient with cells containing genes that were edited using the revolutionary CRISPR–Cas9 technique. The nascent trials are part of the process of understanding how the cutting edge gene-editing technique can boost scientists’ ability to combat cancer …

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial
8 years, 4 months ago

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial

Live Mint  

New Delhi: Close to a month ago, a team led by oncologist Lu You at Sichuan University’s West China Hospital in Chengdu injected a patient with cells containing genes that were edited using the revolutionary CRISPR–Cas9 technique. The nascent trials are part of the process of understanding how the cutting edge gene-editing technique can boost scientists’ ability to combat cancer …

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial
8 years, 4 months ago

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial

Live Mint  

New Delhi: Close to a month ago, a team led by oncologist Lu You at Sichuan University’s West China Hospital in Chengdu injected a patient with cells containing genes that were edited using the revolutionary CRISPR–Cas9 technique. The nascent trials are part of the process of understanding how the cutting edge gene-editing technique can boost scientists’ ability to combat cancer …

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial
8 years, 4 months ago

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial

Live Mint  

New Delhi: Close to a month ago, a team led by oncologist Lu You at Sichuan University’s West China Hospital in Chengdu injected a patient with cells containing genes that were edited using the revolutionary CRISPR–Cas9 technique. The nascent trials are part of the process of understanding how the cutting edge gene-editing technique can boost scientists’ ability to combat cancer …

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial
8 years, 4 months ago

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial

Live Mint  

New Delhi: Close to a month ago, a team led by oncologist Lu You at Sichuan University’s West China Hospital in Chengdu injected a patient with cells containing genes that were edited using the revolutionary CRISPR–Cas9 technique. The nascent trials are part of the process of understanding how the cutting edge gene-editing technique can boost scientists’ ability to combat cancer …

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial
8 years, 4 months ago

Gene editing the new ‘Sputnik’ race as CRISPR technique begins clinical trial

Live Mint  

New Delhi: Close to a month ago, a team led by oncologist Lu You at Sichuan University’s West China Hospital in Chengdu injected a patient with cells containing genes that were edited using the revolutionary CRISPR–Cas9 technique. The nascent trials are part of the process of understanding how the cutting edge gene-editing technique can boost scientists’ ability to combat cancer …

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