Scientists decode how smoking worsens Covid-19 infection
India TodayScientists have decoded how smoking cigarettes facilitates more severe lung infection by the novel coronavirus, an advance that may lead to new therapeutic strategies to help reduce smokers' chances of developing severe Covid-19. Since these stem cells were taken from the lungs of healthy, non-smoking tissue donors, the researchers replicated the effects of smoking by exposing the airway cultures to cigarette smoke for three minutes per day over four days. According to the researchers, smoking may have resulted in more severe SARS-CoV-2 infection, at least in part, by blocking the activity of immune system messenger proteins called interferons. They said interferons play a critical role in the body's early immune response by triggering infected cells to produce proteins to attack the virus, summoning additional support from the immune system, and alerting uninfected cells to prepare to fight the virus.