Human testing of first Nipah virus vaccine begins
11 months, 1 week ago

Human testing of first Nipah virus vaccine begins

India Today  

After successful preclinical trials of a vaccine candidate, called ChAdOx1 NiV, for the brain-swelling Nipah virus, it has entered the human testing phase. Conducted by the University of Oxford with 52 participants, the human trial will assess safety and immune response in individuals aged 18 to 55, a spokesperson for the University's Pandemic Sciences Institute told news agency Reuters. While Oxford Vaccine Group is leading the trial, the human testing is being funded by CEPI, a global coalition that supports the development of vaccines against emerging infectious diseases. Nipah virus infection is a zoonotic illness spread to humans through contact with infected animals such as bats and pigs.

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History of this topic

Nipah test results of 13 people turn -ve, no new cases in state
5 months ago

Nipah test results of 13 people turn -ve, no new cases in state

Hindustan Times  

Kerala breathed a sigh of relief on Monday after the results of the serum tests on 13 people who were in close contact with the 14-year-old boy from Pandikkad in Malappuram turned out to be negative for Nipah virus. The state had been on high alert since the boy died of Nipah virus at a Government Medical College Hospital in …

Oxford scientists launch first human vaccine trials for deadly Nipah virus
11 months, 1 week ago

Oxford scientists launch first human vaccine trials for deadly Nipah virus

The Hindu  

Scientists at the University of Oxford in the U.K. have launched first-in-human vaccine trials for the deadly Nipah virus which impacts many Asian countries, including India. "Nipah virus was first identified in 1998, and yet 25 years on the global health community still has no approved vaccines or treatments for this devastating disease," said the trial's Principal Investigator, Brian Angus, …

The science behind Nipah vaccine: How ChAdOx1 NipahB vaccine works
11 months, 1 week ago

The science behind Nipah vaccine: How ChAdOx1 NipahB vaccine works

India Today  

In a major development toward combating the deadly Nipah virus, scientists have developed a vaccine candidate known as ChAdOx1 NiV, which has shown promising results in preclinical trials and has now entered human testing phases. The ChAdOx1 NiV vaccine uses a replication-deficient chimpanzee adenoviral vector, ChAdOx1, which has been engineered to express the NiV glycoprotein. When challenged with the lethal …

ICMR considers developing vaccine against Nipah
1 year, 3 months ago

ICMR considers developing vaccine against Nipah

Hindustan Times  

The Indian Council of Medical Research is considering developing a vaccine against the Nipah virus, as part of a larger plan to develop a bouquet of essential vaccines. “Our biggest asset at the moment is that we have developed vaccines on diverse platforms such -- DNA vaccine, mRNA vaccine, adenoviral vector vaccine, protein subunit vaccine, and nasal vaccine -- and …

Nipah virus outbreak | India reaches out to Australia for monoclonal antibody doses
1 year, 3 months ago

Nipah virus outbreak | India reaches out to Australia for monoclonal antibody doses

The Hindu  

India has reached out to Australia seeking to restock monoclonal antibody doses to combat the Nipah virus and is expecting 20 more doses soon, Indian Council of Medical Research head Dr. Rajiv Bahl said on Friday. “The mortality among the infected is very high in Nipah — between 40% and 70% — compared to the mortality in COVID, which was …

What is Nipah Virus? Symptoms, diagnosis and treatment
1 year, 3 months ago

What is Nipah Virus? Symptoms, diagnosis and treatment

India Today  

Nipah virus has once again been detected in Kerala's Kozhikode district, marking the third occurrence of the virus in the area since 2018. According to the World Health Organisation, Nipah Virus is defined as a zoonotic illness transmitted from animals to humans and can also be spread through contaminated food or direct person-to-person contact. NIPAH VIRUS SIGNS AND SYMPTOMS: Human …

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak
3 years, 3 months ago

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak

NPR  

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak Enlarge this image toggle caption C.K. "It's really difficult to establish the cause of the boy's illness," says Dr. Thekkumkara Surendran Anish, associate professor of community medicine at the Government Medical College in Thiruvananthapuram. "We have a very clear understanding of how Nipah virus moves …

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease
3 years, 3 months ago

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease

Firstpost  

Nipah virus or, which was first identified during an outbreak in Kampung Sungai Nipah, Malaysia in 1998, is primarily a zoonotic disease carried by fruit bats of the Pteropodidae family Indian state of Kerala, which has seen a previous outbreak of Nipah virus in 2018 and stray cases going back to as far as 2001, has again reported a case …

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