Human testing of first Nipah virus vaccine begins
1 year, 2 months ago

Human testing of first Nipah virus vaccine begins

India Today  

After successful preclinical trials of a vaccine candidate, called ChAdOx1 NiV, for the brain-swelling Nipah virus, it has entered the human testing phase. Conducted by the University of Oxford with 52 participants, the human trial will assess safety and immune response in individuals aged 18 to 55, a spokesperson for the University's Pandemic Sciences Institute told news agency Reuters. While Oxford Vaccine Group is leading the trial, the human testing is being funded by CEPI, a global coalition that supports the development of vaccines against emerging infectious diseases. Nipah virus infection is a zoonotic illness spread to humans through contact with infected animals such as bats and pigs.

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History of this topic

Nipah virus: 17, including deceased victim’s close relatives in Kerala, test negative
8 months ago

Nipah virus: 17, including deceased victim’s close relatives in Kerala, test negative

The Hindu  

The serum samples of 17 people who had contacted a 15-year-old boy who died of Nipah virus at Pandikkad tested negative on Tuesday. Health Minister Veena George said here on Tuesday that legal proceedings would be initiated against those who violate the Nipah protocol. Ms. George said that those tested negative included the close relatives of the Nipah victim. Surveillance …

Nipah test results of 13 people turn -ve, no new cases in state
8 months ago

Nipah test results of 13 people turn -ve, no new cases in state

Hindustan Times  

Kerala breathed a sigh of relief on Monday after the results of the serum tests on 13 people who were in close contact with the 14-year-old boy from Pandikkad in Malappuram turned out to be negative for Nipah virus. The state had been on high alert since the boy died of Nipah virus at a Government Medical College Hospital in …

Oxford scientists launch first human vaccine trials for deadly Nipah virus
1 year, 2 months ago

Oxford scientists launch first human vaccine trials for deadly Nipah virus

The Hindu  

Scientists at the University of Oxford in the U.K. have launched first-in-human vaccine trials for the deadly Nipah virus which impacts many Asian countries, including India. "Nipah virus was first identified in 1998, and yet 25 years on the global health community still has no approved vaccines or treatments for this devastating disease," said the trial's Principal Investigator, Brian Angus, …

Human vaccine trials begin in UK for brain swelling Nipah Virus
1 year, 2 months ago

Human vaccine trials begin in UK for brain swelling Nipah Virus

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy The University of Oxford has launched a new clinical trial to …

The science behind Nipah vaccine: How ChAdOx1 NipahB vaccine works
1 year, 2 months ago

The science behind Nipah vaccine: How ChAdOx1 NipahB vaccine works

India Today  

In a major development toward combating the deadly Nipah virus, scientists have developed a vaccine candidate known as ChAdOx1 NiV, which has shown promising results in preclinical trials and has now entered human testing phases. The ChAdOx1 NiV vaccine uses a replication-deficient chimpanzee adenoviral vector, ChAdOx1, which has been engineered to express the NiV glycoprotein. When challenged with the lethal …

ICMR considers developing vaccine against Nipah
1 year, 6 months ago

ICMR considers developing vaccine against Nipah

Hindustan Times  

The Indian Council of Medical Research is considering developing a vaccine against the Nipah virus, as part of a larger plan to develop a bouquet of essential vaccines. “Our biggest asset at the moment is that we have developed vaccines on diverse platforms such -- DNA vaccine, mRNA vaccine, adenoviral vector vaccine, protein subunit vaccine, and nasal vaccine -- and …

Nipah virus outbreak | India reaches out to Australia for monoclonal antibody doses
1 year, 6 months ago

Nipah virus outbreak | India reaches out to Australia for monoclonal antibody doses

The Hindu  

India has reached out to Australia seeking to restock monoclonal antibody doses to combat the Nipah virus and is expecting 20 more doses soon, Indian Council of Medical Research head Dr. Rajiv Bahl said on Friday. “The mortality among the infected is very high in Nipah — between 40% and 70% — compared to the mortality in COVID, which was …

What is Nipah Virus? Symptoms, diagnosis and treatment
1 year, 6 months ago

What is Nipah Virus? Symptoms, diagnosis and treatment

India Today  

Nipah virus has once again been detected in Kerala's Kozhikode district, marking the third occurrence of the virus in the area since 2018. According to the World Health Organisation, Nipah Virus is defined as a zoonotic illness transmitted from animals to humans and can also be spread through contaminated food or direct person-to-person contact. NIPAH VIRUS SIGNS AND SYMPTOMS: Human …

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak
3 years, 6 months ago

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak

NPR  

Why The World Should Be More Than A Bit Worried About India's Nipah Virus Outbreak Enlarge this image toggle caption C.K. "It's really difficult to establish the cause of the boy's illness," says Dr. Thekkumkara Surendran Anish, associate professor of community medicine at the Government Medical College in Thiruvananthapuram. "We have a very clear understanding of how Nipah virus moves …

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease
3 years, 6 months ago

Twelve-yr-old in Kerala succumbs to Nipah virus infection; symptoms, origin, causes of disease

Firstpost  

Nipah virus or, which was first identified during an outbreak in Kampung Sungai Nipah, Malaysia in 1998, is primarily a zoonotic disease carried by fruit bats of the Pteropodidae family Indian state of Kerala, which has seen a previous outbreak of Nipah virus in 2018 and stray cases going back to as far as 2001, has again reported a case …

Potential Oxford vaccine fails to prevent coronavirus spread in monkeys, but protects from pneumonia
4 years, 10 months ago

Potential Oxford vaccine fails to prevent coronavirus spread in monkeys, but protects from pneumonia

The Hindu  

A high-profile potential vaccine for COVID-19 being tested by researchers at Oxord University failed to protect vaccinated monkeys from being infected by the virus. The vaccine candidate, ChAdOx1 nCoV-19, being tested is a weakened form a common cold virus that affects chimpanzees but has been neutered to prevent replication in humans. Rajesh Gokhle, Faculty, National Institute of Immunology and former …

Human Trials Of Oxford University Coronavirus Vaccine To Begin From Tomorrow
4 years, 11 months ago

Human Trials Of Oxford University Coronavirus Vaccine To Begin From Tomorrow

ABP News  

London: The UK government on Tuesday announced that the human trial of a potential COVID-19 candidate vaccine being developed by researchers at the University of Oxford will begin from Thursday. UK Health Secretary Matt Hancock, during the daily press conference at 10 Downing Street, said the government will provide 20 million pounds to the Oxford research team to help fund …

Coronavirus: First human trial of vaccine begins in US
5 years ago

Coronavirus: First human trial of vaccine begins in US

India Today  

Supported by a global coalition founded by India and Norway, the US has begun the phase one clinical trial of an investigational vaccine designed to protect against the coronavirus disease which has claimed the lives of over 7,000 people globally. "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director …

Nipah virus: Experimental antiviral drug shows promise
5 years, 8 months ago

Nipah virus: Experimental antiviral drug shows promise

The Hindu  

In a new study published last month, researchers from the National Institutes of Health, U.S., have shown that Remdesivir was able to treat four African green monkeys which were given a lethal dose of Nipah virus. Eight monkeys were inoculated with a lethal dose of Nipah virus Bangladesh strain, and, 24 hours later, four of them were treated intravenously with …

Nipah kills one more in Kerala's Kozhikode as death toll rises to 17; victim had tested negative for virus on first occasion
6 years, 9 months ago

Nipah kills one more in Kerala's Kozhikode as death toll rises to 17; victim had tested negative for virus on first occasion

Firstpost  

With the death toll rising to 17, one more person who contracted the Nipah Virus infection passed away in Khozikode, Kerala on 1 June. The Nipah virus killed one more person in Kerala’s Kozhikode district on Friday, taking the death toll to 17, reports said. Nipah virus infection is a newly emerging zoonosis that causes severe disease in both animals …

Nipah virus: India seeks Austraila's help as death toll reaches 12, asks for antibody to test 'neutralisation' of virus
6 years, 10 months ago

Nipah virus: India seeks Austraila's help as death toll reaches 12, asks for antibody to test 'neutralisation' of virus

Firstpost  

In the wake of Nipah virus cases in Kerala, the Indian Council for Medical Research has written to the Queensland government in Australia asking it to provide an antibody developed to test if it can “neutralise” the virus in humans. New Delhi: In the wake of Nipah virus cases in Kerala, the Indian Council for Medical Research has written to …

No new Nipah deaths, one more tested positive
6 years, 10 months ago

No new Nipah deaths, one more tested positive

The Hindu  

One more person undergoing treatment at the Government Medical College Hospital here has been tested positive for the Nipah virus infection. Of the three people currently undergoing treatment at hospitals and whose blood and body fluid samples have been tested positive for the Nipah infection so far, one is from Malappuram district and two are from Kozhikode district. It may …

Human trials of Ebola vaccine to start next week
10 years, 6 months ago

Human trials of Ebola vaccine to start next week

India TV News  

Washinton: The US government announced on Thursday that it will start initial human trials of Ebola vaccine next week. The US National Institutes of Health said in a statement that the phase one clinical trial will determine if a vaccine, co-developed by the National Institute of Allergy and Infectious Diseases and GlaxoSmithKline, is safe and induces an adequate immune response, …

NIH to launch Ebola vaccine trials in humans
10 years, 7 months ago

NIH to launch Ebola vaccine trials in humans

LA Times  

The National Institutes of Health has announced the first clinical trial of a vaccine to protect healthy people from infection by the Ebola virus, which is responsible for an estimated 1,550 deaths throughout West Africa. NIH director Francis Collins on Thursday called the human safety trials, which are to start next week in Bethesda, Md., the latest in a series …

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