Q&A: Why CRISPR-Cas9 is being hailed as the scientific ‘Breakthrough of the Year’
CRISPR is having a moment. Scientists who use this technology say it has made targeting and changing genes in a cell’s DNA easier and more precise than ever before. Paul Knoepfler, a stem cell researcher at UC Davis, describes CRISPR as a molecular Swiss army knife: It’s part genome scanner, part scissors to cut the DNA, and part pencil to re-write the genetic code. However, as the technology continues to get better CRISPR could be used to correct the faulty DNA that’s responsible for genetic diseases like cystic fibrosis, sickle cell anemia, hemophilia and perhaps muscular dystrophy. Scientists from around the world recently gathered for the International Summit for Gene Editing in Washington, D.C., to discuss technologies like CRISPR and the ethics of using them.


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