Decoding the script: On the Genome India Project and its sequencing 10,000 Indian genomes
9 months, 3 weeks ago

Decoding the script: On the Genome India Project and its sequencing 10,000 Indian genomes

The Hindu  

The Genome India Project, a project funded and coordinated by the Department of Biotechnology, announced that it had finished sequencing 10,000 Indian genomes. This means that the complete genomes — the DNA blueprint that constitutes and maintains human bodies — from 10,000 individuals were analysed to create a ‘reference’ Indian human genome. In a way, the latest enterprise would be akin to the creation of the first ever detailed map of India — with all political units, key geographical and topographical features — as opposed to a world map prepared elsewhere, with India just one of several countries and devoid of granular detail. When the Human Genome Project published its reference ‘human genome’ in 2003, at a cost of nearly $3 billion, it rang with a ‘brave-new-world’ promise of humanity having finally decoded the secrets of the genome, mapping every awry gene to a disease and a future of ‘personalised medicine’.

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History of this topic

Data — A healthy way to assess progress
8 months, 1 week ago

Data — A healthy way to assess progress

The Hindu  

The undoubtedly biggest story in healthcare in India last week, came of all things, from the Lancet. Going back to the COVID-19 pandemic, the Lancet said that another contentious issue is the lack of credibility of India’s continuing claim that only 0·48 million people died as a result of the COVID-19 pandemic, whereas the World Health Organisation and other estimates …

What can the 10,000 genome project tell us about India’s health | In Focus podcast
8 months, 2 weeks ago

What can the 10,000 genome project tell us about India’s health | In Focus podcast

The Hindu  

India announced recently, that it has completed the 10,000 genome project – a reference database of whole-genome sequences, from people in India. This project is seen as an important step to find out about genetic variants that are unique to India, to customise drugs and gene-based therapies, give us answers about certain diseases, and to provide a deeper insight into …

What is Genome Sequencing? How Study of 10,000 Individuals is a Watershed in India’s Healthcare
9 months, 3 weeks ago

What is Genome Sequencing? How Study of 10,000 Individuals is a Watershed in India’s Healthcare

News 18  

Indian scientists are close to completing reference genome, with sequencing of samples from 10,000 individuals from around 99 communities already done. Union science and technology minister Jitendra Singh said genome study or sequencing will determine the future healthcare strategies across the world, both therapeutically and prophylactically. “It can also help in identifying resistance indicating variants, for examples, genes that might …

Indian scientists complete sequencing of 10,000 genomes for database
9 months, 3 weeks ago

Indian scientists complete sequencing of 10,000 genomes for database

India TV News  

Scientists have recently completed the sequencing of genomes from 10,000 individuals across diverse Indian communities. Why it matters Sequencing genomes—essentially mapping out an individual's genetic makeup—is crucial for shaping future healthcare strategies worldwide, both in treatment and prevention. The need for Indian solutions Union minister emphasised the importance of finding solutions tailored to Indian needs, given the country's emergence as …

‘At least 10% of the human genome is unchanged across mammal species’
1 year, 7 months ago

‘At least 10% of the human genome is unchanged across mammal species’

The Hindu  

By comparing the genetic blueprints of an array of animals, scientists are gaining new insights into our own species and all we share with other creatures. One study found that at least 10% of the human genome is largely unchanged across species. “One of the really cool things about mammals is that at this point in time, they’ve basically adapted …

Explained | What is genome sequencing and why does the Genome India Project matter?
1 year, 8 months ago

Explained | What is genome sequencing and why does the Genome India Project matter?

The Hindu  

The story so far: The Department of Biotechnology recently said that the exercise to sequence 10,000 Indian human genomes and create a database under the Centre-backed Genome India Project is about two-thirds complete. The process of whole-genome sequencing, made possible by the Human Genome Project, now facilitates the reading of a person’s individual genome to identify differences from the average …

10,000 Indian genomes to be sequenced by year-end
1 year, 8 months ago

10,000 Indian genomes to be sequenced by year-end

The Hindu  

The Genome India Project, a Centre-backed initiative to sequence 10,000 Indian human genomes and create a database, is about two-thirds through, said Rajesh Gokhale, Secretary, Department of Biotechnology. We expect the 10,000 genomes to be completely sequenced by the end of the year,” said Mr. Gokhale at a conference organised by the Association of Biotech-Led Enterprises, an industry group, on …

Scientists condemn project to study ‘racial purity’ of Indian population
2 years, 6 months ago

Scientists condemn project to study ‘racial purity’ of Indian population

The Hindu  

Over a 100 leading biologists, historians, anthropologists and intellectuals have written a joint letter to the Ministry of Culture protesting its purported plans to fund a project to study “genetic similarities and differences in the DNA profiles of Indian population groups.” Last month media reports surfaced of a plan involving the Anthropological Survey of India, some scientists at the Lucknow-based …

EXPLAINED: Why Genome Sequencing Results Take So Long, the Cost and its Importance in Public Health
2 years, 11 months ago

EXPLAINED: Why Genome Sequencing Results Take So Long, the Cost and its Importance in Public Health

News 18  

Omicron, the latest coronavirus variant fuelling the third wave of the pandemic in India, can be identified only through genome sequencing. But, as of now, genome sequencing results take anywhere between five and 12 days after samples are submitted. Highly equipped labs capable of carrying out a genome sequencing will need at least 300 samples to begin the process. Hence, …

Goa to Get Genome Sequencing Machine Under USAID Project
3 years ago

Goa to Get Genome Sequencing Machine Under USAID Project

News 18  

Goa will get a genome sequencing machine free of cost under an international programme dealing with epidemic control and the equipment is likely to become operational by mid-February, state Health Minister Vishwajit Rane said on Thursday. Talking to reporters, he said the coastal state will get the genome sequencing machine funded by the United States Agency for International Development ’s …

Genomic sequencing hubs must be made a permanent part of India’s pandemic response
3 years, 4 months ago

Genomic sequencing hubs must be made a permanent part of India’s pandemic response

Firstpost  

Public labs put into action by the INSACOG for this purpose are not adequately funded and have the capacity to process only 30,000 samples a month. To achieve the five percent sequencing target, India must process 75,000 samples a month which is 2.5 times the current scale. Making private sector labs a part of the genome sequencing process can help …

B.1.617.2 becoming dominant variant in India, finds genome sequencing
3 years, 7 months ago

B.1.617.2 becoming dominant variant in India, finds genome sequencing

India Today  

The United Kingdom has been closely watching the movement of the sub-lineages of the B.1.617 variant that originated in India - B1617.1, B1617.2, and B.617.3. Experts in genomic sequencing of Covid-19 variants in India have now revealed that cases which show B.1.617.2 are slowly eclipsing almost all other variants, including B.1.1.7 -- the Kent variant that originated in the UK. …

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