COVID-19 research roundup: Benefits of steroid for severe COVID-19 confirmed; recovered still susceptible
4 years, 5 months ago

COVID-19 research roundup: Benefits of steroid for severe COVID-19 confirmed; recovered still susceptible

Firstpost  

The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus. Even during a pandemic, they said, when it might be tempting to simply “give all therapies a chance,” in order for patients’ outcomes to improve “there will need to be fewer small or inconclusive studies and more studies such as the dexamethasone trial.” Immune cells may recognize SARS-CoV-2 years later Researchers in Singapore are not worried that antibodies to the novel coronavirus fade quickly. Interferon levels low in severe COVID-19 Low blood levels of a type of interferon could identify COVID-19 patients at high risk for severe pneumonia and acute respiratory distress syndrome. Heart disease could explain odd COVID-19 blood reports Severe COVID-19 predominantly affects the lungs, but elevated blood levels of troponin, a protein released during heart injury, also are common. The main message, Knight added, is that when troponin levels are elevated in COVID-19 patients with no apparent reason, further workup could reveal undiagnosed heart disease.

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History of this topic

Covid19 triggers massive inflammation? Here's what the experts have to say
2 years, 9 months ago

Covid19 triggers massive inflammation? Here's what the experts have to say

India TV News  

US researchers have identified the reason why Covid-19 causes severe inflammation in some people, leading to acute respiratory distress and multi-organ damage. They found that SARS-CoV-2 can infect monocytes - immune cells in the blood that act as "sentinels" or early responders to infection - as well as macrophages, similar immune cells in the lungs. "In the infected patients, about …

Here's why mild Covid-19 infection very unlikely to cause lasting heart damage
3 years, 8 months ago

Here's why mild Covid-19 infection very unlikely to cause lasting heart damage

Hindustan Times  

Mild Covid-19 infection is very unlikely to cause lasting damage to the structure or function of the heart, according to a study. This study of 149 healthcare workers recruited from Barts Health and Royal Free London NHS Trusts is the largest and most detailed study to date into mild Covid-19 infection and its longer-term impact on the heart. It follows …

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists
4 years, 1 month ago

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists

News 18  

Most adults with moderate-to-severe COVID-19 have a suppressed immune response against the novel coronavirus rather than life-threatening hyper-inflammation, according to a study which suggests steroids such as dexamethasone should be reserved for the sickest patients. According to the research, published in the journal Science Advances, fewer than 5 per cent of the COVID-19 patients, including some of the sickest individuals, …

‘Breakthrough finding’ offers clues about why certain COVID-19 patients die
4 years, 1 month ago

‘Breakthrough finding’ offers clues about why certain COVID-19 patients die

LA Times  

What makes some COVID-19 patients so much sicker than others? In an international study published last month in the journal Science, 10% of nearly 1,000 COVID-19 patients who developed life-threatening pneumonia had antibodies that disable key immune system proteins called interferons. “This is one of the most important things we’ve learned about the immune system since the start of the …

Treatment for 6 months needed post Covid-19
4 years, 2 months ago

Treatment for 6 months needed post Covid-19

Deccan Chronicle  

Hyderabad: Fifteen to 20 per cent of Covid-19 recovered patients are coming back to hospitals with complaints of lung fibrosis, clotting in blood vessels, low functioning of kidney and heart and paralytic attack. Gandhi Hospital which has been the main centre in Telangana state for Covid-19 treatment is seeing many patients return with complaints. With so many people getting infected …

Advances In ICU Care Are Saving More Patients Who Have COVID-19
4 years, 3 months ago

Advances In ICU Care Are Saving More Patients Who Have COVID-19

NPR  

Advances In ICU Care Are Saving More Patients Who Have COVID-19 Enlarge this image toggle caption Mark Felix/AFP via Getty Images Mark Felix/AFP via Getty Images If you think all the coronavirus news is bad, consider the uplifting story of Don Ramsayer. "We have very much replicated what's been seen worldwide, which is over time the mortality in ICUs have …

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients
4 years, 4 months ago

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients

NPR  

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients Enlarge this image toggle caption Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Three new studies strongly support using inexpensive and widely available drugs to treat people who are seriously ill with COVID-19. Sponsor Message "Giving steroids to COVID-19 could have been …

COVID-19 can affect almost all organs, say experts at AIIMS
4 years, 4 months ago

COVID-19 can affect almost all organs, say experts at AIIMS

India TV News  

Not just the lungs, COVID-19 can affect almost all organs and the initial symptoms may be totally unrelated to chest complaints, experts at AIIMS in New Delhi said on Wednesday. Experts from the institute, including its director Dr Randeep Guleria, Dr MV Padma Srivastava, head of department of Neurology, Dr Ambuj Roy, Professor of Cardiology and Dr Neeraj Nischal, Associate …

A blood test can tell which COVID-19 patient should get steroid treatment and who would react adversely to it
4 years, 5 months ago

A blood test can tell which COVID-19 patient should get steroid treatment and who would react adversely to it

Firstpost  

The study suggested steroid therapy may benefit patients with severe inflammation, but may negatively impact those with less severe inflammation COVID-19 has affected more than 15 million people in the world so far. Now, a group of researchers at the Albert Einstein College of Medicine say that the levels of CRP may have something to do with the effects of …

Dexamethasone | WHO says more understanding needed on steroid
4 years, 6 months ago

Dexamethasone | WHO says more understanding needed on steroid

The Hindu  

The emergencies chief of the World Health Organization welcomed the news this week that dexamethasone, a cheap steroid, was shown in a British trial to reduce deaths among patients critically ill with the coronavirus, but said it was too soon to change how patients are treated. “It’s one of the breakthroughs we’re going to need to effectively deal with COVID-19, …

How dexamethasone might lead researchers to better COVID-19 treatments
4 years, 6 months ago

How dexamethasone might lead researchers to better COVID-19 treatments

LA Times  

The steroid drug dexamethasone can be lifesaving for patients with severe COVID-19. In preliminary clinical trial results announced Tuesday, patients on mechanical ventilators who were treated with the steroid dexamethasone were 35% less likely to die of COVID-19 than their counterparts who got standard care without the drug. A medication like dexamethasone is a “blunt instrument,” said Dr. Steven J. …

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