Explained | Does data support booster dose of same vaccine?
The story so far: On January 5, five days before the rollout of the ‘precaution dose’, scientifically called a third or booster dose, for people older than 60 years with comorbidities, health-care and frontline workers, the Government announced that all eligible individuals will receive a homologous — the same vaccine as used in the primary vaccination— vaccine as the third dose. On December 10, the Subject Expert Committee had asked the Serum Institute of India to submit a proposal to generate clinical trial data for a booster dose. According to the minutes of the meeting, based on Serum Institute’s request for permission to administer the Covishield booster dose six months after the second dose, the SEC noted that the company has “not presented any data from the Indian population for the requirement of booster dose based on demographical profile and waning immunogenicity”. The COV-BOOST study by researchers at the University of Southampton, U.K., evaluated seven different vaccines as a booster dose in participants who had received either two doses of the Oxford vaccine or the Pfizer vaccine.
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