Crispr: The science behind a 'game-changing' gene-editing technique
9 years, 8 months ago

Crispr: The science behind a 'game-changing' gene-editing technique

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy It has been less than five years since it was first discovered yet it is fair to say that the gene-editing technique known as Crispr-Cas9 has in that time become a recognised “game changer” in the field of genetics. Crispr, which stands for “clustered regularly interspaced short palindromic repeats”, is a guide molecule made of RNA, a close cousin to DNA. Eric Lander, director of the Broad Institute at Harvard University and a pioneer of genomic science, has said that Crispr-Cas9 holds “great therapeutic potential” in human medicine because of its power to edit precise points within the 3bn letters of the human genetic code. “However,” he warned earlier this year, “the technology also raises a more troubling possibility; creating children carrying permanent, heritable changes to the human germ-line DNA.

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History of this topic

Putting the gene editing tool to use
2 months, 2 weeks ago

Putting the gene editing tool to use

The Hindu  

When you edit a letter or a document, you make specific changes in the words and phrases to make the meaning clearer. Gene editing involves changing the sequence of DNA using specific enzymes which can cut DNA at a precise location, thus permitting the removal, addition, or replacement of genetic information within a gene. He then went ahead, obtained a …

RNA editing is the next frontier in gene therapy – here’s what you need to know
4 months ago

RNA editing is the next frontier in gene therapy – here’s what you need to know

Raw Story  

The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA editing. Thanks to recent advances, we now have the tools to directly change someone’s DNA – this has paved the way for gene editing as a type of gene therapy. RNA editing doesn’t permanently change a person’s DNA, but rather alters the …

How CRISPR can edit entire microbial populations in our gut
5 months, 4 weeks ago

How CRISPR can edit entire microbial populations in our gut

NPR  

How CRISPR can edit entire microbial populations in our gut Part 4 of the TED Radio Hour episode Augmenting Humans. Jennifer Doudna's gene-editing technology CRISPR can now manipulate populations of microbes. Together with her collaborator Emmanuelle Charpentier, Doudna has developed a technology called CRISPR-Cas9 that enables genome editing in any living cell. Web Resources Related TED Bio: Jennifer DoudnaRelated TED …

New AI creates molecules not found in nature that can CHANGE human genes to cure even the rarest of diseases
11 months ago

New AI creates molecules not found in nature that can CHANGE human genes to cure even the rarest of diseases

Daily Mail  

AI is used to compose music, suggests recipes and make investment decisions, but a company has designed a system that can edit human genes. The AI was trained on a database of 5.1 million CRISPR-associated proteins, allowing it to create potential molecules that could be used in gene editing ‘Attempting to edit human DNA with an AI-designed biological system was …

Scientists can edit HIV from cells, hinting at cure: Report
1 year ago

Scientists can edit HIV from cells, hinting at cure: Report

India Today  

Scientists can eliminate HIV infection from cells using the powerful CRISPR technology, BBC reported. However, the delivery of these systems remains a significant issue and much more work will be needed to demonstrate results in these cell assays can happen in an entire body for a future therapy," Dr James Dixon told Science Media Centre. Virus expert Dr Jonathan Stoye …

With CRISPR poised to revolutionise therapy, a pause to consider ethical issues
1 year, 1 month ago

With CRISPR poised to revolutionise therapy, a pause to consider ethical issues

The Hindu  

“We will each write a ghost story”, said Lord Byron; and his proposition was acceded to. With the first gene editing technology securing approval for the treatment of sickle cell anemia and beta-thalassemia, we transcend into a new revolutionary phase. Casgevy and Lyfgenia, the two cell-based gene therapies approved by the Food and Drug Administration for sickle cell anemia treatment …

The era of CRISPR therapeutics is here – what can we expect? | Explained
1 year, 3 months ago

The era of CRISPR therapeutics is here – what can we expect? | Explained

The Hindu  

Imagine a future where genetic anomalies can be precisely targeted and corrected using genome editing – a giant leap from our ability to sequence or read human genomes two decades ago. The 2020 Nobel Prize didn’t only honour the researchers: it also symbolised the start of a time in which people couldn’t just read human genomes but also edit or …

The First Crispr Medicine Is Now Approved in the US
55 years, 3 months ago

The First Crispr Medicine Is Now Approved in the US

Wired  

“This is a terrible disease,” says Samarth Kulkarni, president and CEO of Crispr Therapeutics. Casgevy uses the Nobel Prize–winning technology Crispr to modify patients’ cells so that they produce healthy hemoglobin instead. Of the 31 patients followed for two years, 29 have been free of pain crises for at least a year after receiving a single dose of their own …

Jennifer Doudna Believes Crispr Is for Everyone
55 years, 3 months ago

Jennifer Doudna Believes Crispr Is for Everyone

Wired  

It’s been a monumental year for Crispr, the molecular tool scientists use to edit genetic material. This November, the United Kingdom authorized the first medical treatment using Crispr gene editing, giving people with sickle cell disease new opportunities to receive a one-time therapy to prevent episodes of terrible pain. “It’s expensive,” Jennifer Doudna, the pioneering biochemist who won a Nobel …

Crispr Wants to Feed the World
2 years, 2 months ago

Crispr Wants to Feed the World

Wired  

Ten years after its discovery, the implications of Crispr genome editing are profound and far-reaching, and we are only getting started. For instance, following on the heels of the initial clinical trial results, the first agricultural applications using Crispr have recently entered the market: A US Food and Drug Administration–approved edit to cattle genes re-creates a slick coat that is …

A Bold Effort to Cure HIV—Using Crispr
2 years, 5 months ago

A Bold Effort to Cure HIV—Using Crispr

Wired  

In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to snip the AIDS-causing virus out of his cells. “What we’re trying to do is return the cell to a near-normal state,” says Daniel Dornbusch, CEO of Excision BioTherapeutics, the San Francisco-based biotech company that’s running the trial. “HIV is a …

A New Kind of Genome Editing Is Here to Fine-Tune DNA
2 years, 9 months ago

A New Kind of Genome Editing Is Here to Fine-Tune DNA

Wired  

By now you’ve heard of Crispr gene editing—the molecular scissors that allow scientists to make targeted changes to an organism’s DNA. While gene editing relies on changing the DNA code itself, epigenetic editing involves dialing the expression of individual genes up or down. The Crispr injection brought Arc expression back up to baseline levels, what Pandey refers to as a …

Can Genetic Modification Technology CRISPR be Applied to Covid-19 diagnostics?
3 years, 7 months ago

Can Genetic Modification Technology CRISPR be Applied to Covid-19 diagnostics?

News 18  

US scientists have repurposed genetic modification technology CRISPR to identify antibodies in patient blood samples in a move that could inspire a new class of medical diagnostics, particularly in the treatment of Covid-19. The technology involves customisable collections of proteins which are attached to a variant of Cas9, the protein at the heart of CRISPR, that will bind to DNA …

New CRISPR tech can revolutionise gene therapy, renew hope for treating genetic diseases
4 years, 1 month ago

New CRISPR tech can revolutionise gene therapy, renew hope for treating genetic diseases

Firstpost  

The day a muddled mob stormed the US Capitol building, a team of American researchers published a paper in Nature that signified a landmark in gene therapy. The head of the US National Institutes of Health, Francis Collins had joined forces with Harvard University professor David Liu and others to tackle progeria, a genetic disorder that causes children to age …

CRISPR gene editing can cause unwanted changes in human embryos, study finds
4 years, 5 months ago

CRISPR gene editing can cause unwanted changes in human embryos, study finds

Firstpost  

Instead of addressing genetic mutations, the CRISPR-Cas9 technology appeared to wreak genetic havoc in about half the specimens that the researchers examined A powerful gene-editing tool called CRISPR-Cas9, which this month nabbed the Nobel Prize in Chemistry for two female scientists, can cause serious side effects in the cells of human embryos, prompting them to discard large chunks of their …

Explained: 2020 Nobel Prize in Chemistry
4 years, 5 months ago

Explained: 2020 Nobel Prize in Chemistry

The Hindu  

Emmanuelle Charpentier and Jennifer Doudna were awarded the Nobel Prize in Chemistry 2020 for discovering one of gene technology’s sharpest tools: the CRISPR/Cas9 genetic scissors. Using components of the CRISPR system, researchers can add, remove, or even alter specific DNA sequences. Emmanuelle Charpentier who was studying a bacteria called Streptococcus pyogenes, noticed a previously unknown molecule called tracrRNA. Further studies …

Crispr: What is genome editing? All you need to know about Nobel-winning controversial technology
4 years, 5 months ago

Crispr: What is genome editing? All you need to know about Nobel-winning controversial technology

India Today  

Two women -- Emmanuelle Charpentier and Jennifer Doudna -- were awarded the 2020 Nobel Prize for chemistry by the Nobel Committee on Wednesday. The duo received the Nobel Prize in chemistry award for developing a method of genome editing, or gene editing, likened to "molecular scissors" that offers the promise of one day curing inherited diseases and even cancer. A …

What is CRISPR and why is it controversial?
4 years, 5 months ago

What is CRISPR and why is it controversial?

CNN  

CNN — Two women have won the Nobel prize in chemistry for the development of a revolutionary gene editing tool that’s been described as “rewriting the code of life.” The technique discovered by Emmanuelle Charpentier, the director at the Max Planck Institute for Infection Biology, and Jennifer A. Doudna, a biochemist at the University of California Berkeley, is known as …

Scientists claim to have uses CRISPR for the first time to treat a patient who was blind
5 years ago

Scientists claim to have uses CRISPR for the first time to treat a patient who was blind

Firstpost  

They said that it will take up to a month to see if this surgery worked and has restored the patient’s vision. Scientists say they have used the gene-editing tool CRISPR inside someone’s body for the first time, a new frontier for efforts to operate on DNA, the chemical code of life, to treat diseases. “We think it could open …

First CRISPR gene editing trial in cancer patients points to safety of technique in medical treatments
5 years, 1 month ago

First CRISPR gene editing trial in cancer patients points to safety of technique in medical treatments

Firstpost  

Back in April 2019, an experimental study underway at the University of Pennsylvania made news for its success in using gene editing to treat a form of malignant cancer. Researchers genetically-altered immune cells to encourage them to attack and destroy cancer cells, and managed to cure a patient of sarcoma – a cancer of the soft tissues like muscle, tendons, …

Never-seen-before extracts from 'outrageous' research of disgraced scientist He Jiankui
5 years, 3 months ago

Never-seen-before extracts from 'outrageous' research of disgraced scientist He Jiankui

Daily Mail  

He Jiankui, the disgraced scientist who was internationally condemned for gene-editing twin girls, may have put the health of the children at risk by adding unintended mutations into their genetic code. Dr Vassena adds: 'The idea that editing-derived embryos may one day be able to 'control the HIV epidemic,' as the authors claim, is preposterous. 'It's almost like not editing …

Molecular Scissors Could Help Keep Some Viral Illnesses At Bay
5 years, 4 months ago

Molecular Scissors Could Help Keep Some Viral Illnesses At Bay

NPR  

Molecular Scissors Could Help Keep Some Viral Illnesses At Bay Enlarge this image Susanna M. Hamilton/Broad Communications Susanna M. Hamilton/Broad Communications It's not easy to treat viral infections. Sponsor Message What's different is that the antiviral approach researchers at the Broad Institute in Cambridge are using involves a form of CRISPR called Cas13 that targets specific regions of RNA, not …

CRISPR Approach To Fighting Cancer Called 'Promising' In 1st Safety Test
5 years, 4 months ago

CRISPR Approach To Fighting Cancer Called 'Promising' In 1st Safety Test

NPR  

CRISPR Approach To Fighting Cancer Called 'Promising' In 1st Safety Test Enlarge this image toggle caption Jure Gasparic/EyeEm/Getty Images Jure Gasparic/EyeEm/Getty Images The powerful gene-editing technique known as CRISPR has raised a lot of hope in recent years for its potential to offer new ways to treat many diseases, including cancer. On Wednesday, researchers revealed data from the first study …

Scientists Create New, More Powerful Technique To Edit Genes
5 years, 5 months ago

Scientists Create New, More Powerful Technique To Edit Genes

NPR  

Scientists Create New, More Powerful Technique To Edit Genes Scientists have created a new way to edit DNA that appears to make it even easier to precisely and safely re-write genes. "It's proven difficult to use these molecular scissors to make precise DNA changes in most cell types," says David Liu, a biologist at Harvard, MIT and the Broad Institute …

CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows
5 years, 6 months ago

CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows

NPR  

CRISPR Gene Editing May Offer Path To Cure For HIV, First Published Report Shows Enlarge this image MOLEKUUL/SCIENCE PHOTO LIBRARY/Getty Images/Science Photo Libra MOLEKUUL/SCIENCE PHOTO LIBRARY/Getty Images/Science Photo Libra There's been a lot of excitement lately that the powerful gene-editing technique CRISPR could offer a new way to treat health problems ranging from cancer to blindness. Chinese scientists have published …

For the first time, researchers use gene editing to cure mice of HIV
5 years, 8 months ago

For the first time, researchers use gene editing to cure mice of HIV

Salon  

For the first time in history, researchers have successfully eliminated HIV from infected mice DNA. In a study published on Tuesday in Nature Communications, researchers reported a potential new way to cure HIV, a disease that affects an estimated 1.1 million people in the United States. Fortunately, life expectancy for those living with AIDS has greatly improved over the last …

CRISPR will bring huge shifts to agriculture, food sectors in next 5 years says founder
5 years, 11 months ago

CRISPR will bring huge shifts to agriculture, food sectors in next 5 years says founder

Firstpost  

Gene editing technology CRISPR has found itself in the news a whole lot since it was first invented and used in living systems in 2012 and 2013, respectively. “In the next five years, the most profound thing we’ll see in terms of CRISPR’s effects on everyday lives will be in the agricultural sector,” she told Business Insider. Memphis Meats, a …

CRISPR used to treat two human cancer patients for the first time in UPenn study
5 years, 11 months ago

CRISPR used to treat two human cancer patients for the first time in UPenn study

Firstpost  

Gene-editing technology CRISPR is finally moving out laboratories and into clinical settings around the world. Three years after have passed since the National Institute of Health gave a research team at the University of Pennsylvania the green-light to begin trials for gene-editing technology CRISPR in humans. Researchers at UPenn have used CRISPR to treat two cancer patients so far, the …

First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway
5 years, 11 months ago

First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway

NPR  

Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway Enlarge this image toggle caption Molekuul/Getty Images/Science Photo Library Molekuul/Getty Images/Science Photo Library The powerful gene-editing technique called CRISPR has been in the news a lot. Sponsor Message Research News Scientists Plan To Start Human Trials Testing CRISPR Soon Scientists Plan To Start Human Trials Testing CRISPR Soon 4:30 One …

Preparing to Unleash Crispr on an Unprepared World
6 years ago

Preparing to Unleash Crispr on an Unprepared World

Wired  

Back in the 1980s, researchers began to notice a strange pattern in the genes of many microbes. In 2011, a microbiologist named Emmanuelle Charpentier determined that the Crispr scheme has three key ingredients: an enzyme that acts like a scissors, snipping the strands of the DNA double helix; a guide RNA, which tells the scissors where to cut; and a …

Antibiotics Are Failing Us. Crispr Is Our Glimmer of Hope
6 years, 2 months ago

Antibiotics Are Failing Us. Crispr Is Our Glimmer of Hope

Wired  

Humans and antibiotics have had a good run. According to an analysis of more than 19 million privately insured outpatients in the US, published today in The British Medical Journal, one in seven people were prescribed at least one course of pointless antibiotics in 2016. “Despite decades of investment in education about antibiotic stewardship, providers are still recommending drugs for …

Screening the human future: YouTube, persuasion and genetically engineered children
6 years, 3 months ago

Screening the human future: YouTube, persuasion and genetically engineered children

Salon  

On Sunday, Nov. 25, the scientist He Jiankui claimed the birth of the world’s first genetically engineered children: twins, created by IVF, their DNA altered at fertilization. Instead of “CRISPR-Cas9,” the common name, he insists on the phrase “gene surgery.” It’s a naked attempt to make CRISPR sound precise, like a molecular scalpel. CRISPR is improving in accuracy, but as …

CRISPR: The genetic editing tool that holds promise & peril
6 years, 4 months ago

CRISPR: The genetic editing tool that holds promise & peril

Live Mint  

Chinese researcher He Jiankui has claimed that he used CRISPR to produce the world’s first “designer babies”. Jiankui said he used CRISPR—Clustered Regularly Interspaced Short Palindromic Repeats—to alter the genes of a pair of twins while they were embryos to make the babies resistant to HIV, the virus that causes AIDS. In 2017, a US science and medicine advisory group …

Baby-editing geneticist says a second volunteer in controversial study is pregnant
6 years, 4 months ago

Baby-editing geneticist says a second volunteer in controversial study is pregnant

Firstpost  

He said he used a gene-editing technology known as CRISPR-Cas9 to alter the embryonic genes. A Chinese scientist at the centre of an ethical storm over what he claims are the world’s first genetically edited babies said on 28 November he is proud of his work and revealed that another volunteer is pregnant as part of the research. He Jiankui, …

CRISPR发明者演讲：当我们开始“定制婴儿”，世界会陷入怎样的疯狂？
6 years, 4 months ago

CRISPR发明者演讲：当我们开始“定制婴儿”，世界会陷入怎样的疯狂？

China Daily  

首例人类基因编辑婴儿诞生事件一经出现在网络，便引发争议，其原因并不是这项技术的突破性，而是在人类毫无准备的情况下，为“人类物种”打开了一个面临巨大进化和道德风险的疯狂世界入口。 遗传学专家詹妮弗·道娜（Jennifer Doudna）与同事共同发明了突破性的新技术“基因编辑技术”，被称为CRISPR-Cas9。该工具允许科学家们对DNA进行精确的编辑，这可能对遗传性疾病的治疗有帮助.但也可能会被用来创造所谓的“订制婴儿”。道娜展示了CRISPR-Cas9的作用原理——并要求科学界暂缓脚步，来讨论这个新工具背后的伦理问题。 一起来看看她有关这一问题的演讲： A few years ago, with my colleague, Emmanuelle Charpentier, I invented a new technology for editing genomes. The CRISPR technology allows scientists to make changes to the DNA in cells that could allow us to cure genetic disease. 你可能有兴趣想知道，CRISPR技术其实来自于一个基础的科学研究， 它的主要目的是了解细菌如何与病毒感染进行对抗。 细菌必须在它们的环境里对付病毒。 我们可以这么想， 病毒感染像是个定时炸弹， 细菌在被消灭前， 只有几分钟时间可以拆除炸弹。 很多细菌在它们的细胞里有一种适应力免疫系统叫做"CRISPR"， 它可以使细菌侦测到病毒DNA并消灭它。 Part of the CRISPR system is a protein called …

CRISPR发明者演讲：当我们开始“定制婴儿”，世界会陷入怎样的疯狂？
6 years, 4 months ago

CRISPR发明者演讲：当我们开始“定制婴儿”，世界会陷入怎样的疯狂？

China Daily  

首例人类基因编辑婴儿诞生事件一经出现在网络，便引发争议，其原因并不是这项技术的突破性，而是在人类毫无准备的情况下，为“人类物种”打开了一个面临巨大进化和道德风险的疯狂世界入口。 遗传学专家詹妮弗·道娜（Jennifer Doudna）与同事共同发明了突破性的新技术“基因编辑技术”，被称为CRISPR-Cas9。该工具允许科学家们对DNA进行精确的编辑，这可能对遗传性疾病的治疗有帮助.但也可能会被用来创造所谓的“订制婴儿”。道娜展示了CRISPR-Cas9的作用原理——并要求科学界暂缓脚步，来讨论这个新工具背后的伦理问题。 一起来看看她有关这一问题的演讲： A few years ago, with my colleague, Emmanuelle Charpentier, I invented a new technology for editing genomes. The CRISPR technology allows scientists to make changes to the DNA in cells that could allow us to cure genetic disease. 你可能有兴趣想知道，CRISPR技术其实来自于一个基础的科学研究， 它的主要目的是了解细菌如何与病毒感染进行对抗。 细菌必须在它们的环境里对付病毒。 我们可以这么想， 病毒感染像是个定时炸弹， 细菌在被消灭前， 只有几分钟时间可以拆除炸弹。 很多细菌在它们的细胞里有一种适应力免疫系统叫做"CRISPR"， 它可以使细菌侦测到病毒DNA并消灭它。 Part of the CRISPR system is a protein called …

Scientists, officials in China abhor gene editing that geneticist claims
6 years, 4 months ago

Scientists, officials in China abhor gene editing that geneticist claims

Live Mint  

Beijing/Shanghai: Chinese officials and scientists denounced on Tuesday the claims of a geneticist who said he had created the first gene-edited babies, and a hospital linked to his research suggested its ethical approval had been forged. China’s Genetics Society and the Chinese Society for Stem Cell Research said in a statement He had acted as an “individual” and his work …

Editing our genes
6 years, 6 months ago

Editing our genes

The Hindu  

American biochemist Jennifer Doudna, one of the pioneers of the gene editing tool Crispr-Cas9, woke up in a cold sweat after she dreamt of Adolf Hitler. In the book she co-authored, A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution, Doudna recounts the dream, and acknowledges the “truly incredible power” of the technology, “one that could …

Why DNA Is the Most Exciting Programming Language Today
6 years, 6 months ago

Why DNA Is the Most Exciting Programming Language Today

Wired  

WIRED ICON Sean Parker, Napster cofounder NOMINATES Alex Marson, biologist and infectious disease doctor at UC San Francisco When Sean Parker was young, he cofounded Napster and changed the way we listen to music. The Parker Institute for Cancer Immunotherapy, which he founded in 2016, has dedicated $250 million toward using new technologies like Crispr to teach the human body …

HOW DOES CRISPR DNA EDITING WORK?
6 years, 6 months ago

HOW DOES CRISPR DNA EDITING WORK?

Daily Mail  

The CRISPR gene editing technique is being used an increasing amount in health research because it can change the building blocks of the body. Technically called CRISPR-Cas9, the process involves sending new strands of DNA and enzymes into organisms to edit their genes. Cas9 enzymes can then cut strands of DNA, effectively turning off a gene, or remove sections of …

How safe is CRISPR?
6 years, 8 months ago

How safe is CRISPR?

The Hindu  

The clustered, regularly interspaced, short palindromic repeats, or CRISPR/CRISPR-associated protein 9 system has revolutionised genetic manipulations and made gene editing simpler, faster and easily accessible to most laboratories. On the contrary, a defective P53 protein is ideal for Cas9-mediated editing but makes the cells cancer-prone by introducing genetic changes elsewhere in the genome. Like in the earlier study, the Novartis …

Scared of CRISPR? 40 years on, IVF shows how fears of new medical technology can fade
6 years, 8 months ago

Scared of CRISPR? 40 years on, IVF shows how fears of new medical technology can fade

Salon  

The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. So while the intense media coverage at the time helped inform the public of this new development, the insensitive labeling of Louise Brown as a “test-tube baby” and warnings about dystopian results didn’t stop Americans …

What is Crispr Gene Editing? The Complete WIRED Guide
6 years, 11 months ago

What is Crispr Gene Editing? The Complete WIRED Guide

Wired  

But we won’t get there with the tools we’ve currently got, which is why researchers are now racing to chart the full expanses of the Crispr universe. Each new enzyme will not only advance Crispr’s gene editing powers but also extend its capabilities far beyond DNA manipulation. Because Crispr doesn’t use plant pathogens to manipulate DNA, the USDA has given …

CRISPR: offering a new hope for gene editing in plants, animals and humans
7 years ago

CRISPR: offering a new hope for gene editing in plants, animals and humans

Live Mint  

Even in times as grim as the current global scenario, a few science stories offer hope and optimism. Although CRISPR-Cas9 is primarily known for its use in treating diseases like AIDS, amyotrophic lateral sclerosis and Huntington’s disease, researchers are now looking at furthering its use to tackle famine, lending a hand in creating antibiotics, and even wiping out an entire …

Crispr Isn’t Enough Any More. Get Ready for Gene Editing 2.0
7 years, 3 months ago

Crispr Isn’t Enough Any More. Get Ready for Gene Editing 2.0

Wired  

In fewer than five years, the gene-editing technology known as Crispr has revolutionized the face and pace of modern biology. Since its ability to find, remove, and replace genetic material was first reported in 2012, scientists have published more than 5,000 papers mentioning Crispr. Usually, when we’ve referred to Crispr, we’ve really meant Crispr/Cas9—a riboprotein complex composed of a short …

WHAT IS CRISPR-CAS9?
7 years, 3 months ago

WHAT IS CRISPR-CAS9?

Daily Mail  

The approach has been used previously to edit the HBB gene responsible for a condition called β-thalassaemia. Get ready for genetically engineered 'super chocolate': Scientists use gene editing tools to make cacao trees resistant to disease Gene-editing tool CRISPR-Cas9 could help breed cacao trees that exhibit desirable traits such as enhanced resistance to diseases, a Penn. Revolutionary gene-editing tool CRISPR …

New RNA editing tool can eradicate genetic diseases
7 years, 5 months ago

New RNA editing tool can eradicate genetic diseases

Live Mint  

Boston: Scientists have created a new gene editing tool that tweaks the individual RNA ‘letters’ in human cells without making changes to the entire genome, paving the way for therapies that can reverse disease-causing mutations. “The ability to correct disease-causing mutations is one of the primary goals of genome editing,” said Feng Zhang, from MIT. “This new ability to edit …

Gene editing breakthrough allows precise fixes of humans and could destroy thousands of most deadly diseases
7 years, 5 months ago

Gene editing breakthrough allows precise fixes of humans and could destroy thousands of most deadly diseases

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy A new gene editing breakthrough allows scientists to easily snip out …

CRISPR gene editing technique sheds light on key gene for human embryo development
7 years, 6 months ago

CRISPR gene editing technique sheds light on key gene for human embryo development

Firstpost  

The findings could help scientists to better understand the biology of our early development and lead to new treatment for infertile couples. In a first, researchers have used the CRISPR-Cas9 gene-editing technique to reveal the role of a key gene in human embryos in the first few days of development. The findings published in the journal Nature could help scientists …

Gene editing of human embryos in UK reveals new fertility clue
7 years, 6 months ago

Gene editing of human embryos in UK reveals new fertility clue

CNN  

Story highlights UK scientists have edited human embryos for the first time A key gene has been identified that helps determine the healthy development of human embryos CNN — The DNA of human embryos has been altered and studied for the first time in the UK, offering new insight into the early stages of human development. “We were surprised to …

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