Rethinking Immunotherapy for Cancer: When Is the Best Time to Stop?
1 year, 3 months ago

Rethinking Immunotherapy for Cancer: When Is the Best Time to Stop?

Live Mint  

Immune-boosting drugs have revolutionized cancer care. He is trying to recruit cancer patients to study whether they could do as well with less of Merck’s Keytruda or Bristol-Myers Squibb’s Opdivo, so-called immune checkpoint inhibitors. A report this month in the journal Cancer Research Communications found that most metastatic colon cancer patients who responded well to their initial treatment didn’t experience a worsening of their disease nearly two years after discontinuing the drugs. “All patients probably don’t need a long duration of therapy to have durable benefits," said Dr. Geoffrey Gibney, a melanoma doctor at the Georgetown Lombardi Comprehensive Cancer Center. An oncologist, Prabhash found that head-and-neck cancer patients experienced a significant survival benefit with chemotherapy plus Opdivo at 6% of the dose used in the U.S., compared with patients who got chemotherapy alone.

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History of this topic

Scientist cures her stage 3 cancer with viruses she grew in a lab - after refusing to go through hell of chemo again
4 months, 2 weeks ago

Scientist cures her stage 3 cancer with viruses she grew in a lab - after refusing to go through hell of chemo again

Daily Mail  

When Beata Halassy discovered that her stage 3 breast cancer had returned despite having undergone a mastectomy, she couldn’t bring herself to go through another brutal round of chemo. She writes: ‘The short-term and middle-term outcome of this unconventional treatment, which was devoid of any significant toxicity, was undoubtedly beneficial.’ Dr Beata Halassy developed viruses in her lab that she …

Early detection of tumours can help treat breast cancer, say experts
1 year, 9 months ago

Early detection of tumours can help treat breast cancer, say experts

The Hindu  

Early detection of tumours can help treat breast cancer, say doctors. In a webinar on ‘Breast Cancer Care – Prevention to Advanced Treatment’ held as part of The Hindu Wellness Series, presented by Naruvi Hospitals, on May 28, the doctors said almost 1.78 lakh individuals had been diagnosed at an advanced stage. T. Allwyn Yabesh, consultant, medical oncologist, Naruvi Hospitals, …

Experimental cancer vaccine combined with immunotherapy delayed return of melanoma, Moderna and Merck say
1 year, 11 months ago

Experimental cancer vaccine combined with immunotherapy delayed return of melanoma, Moderna and Merck say

CNN  

CNN — New data from a trial of an investigational mRNA vaccine shows that it reduced the risk of recurrence of the serious skin cancer melanoma when combined with immunotherapy, according to drugmakers Moderna and Merck. In a trial of 157 people who had had surgery to treat melanoma, 78.6% of those who received the personalized vaccine and the immunotherapy …

Immunotherapy is the new era in cancer treatment: Doctors explain
2 years ago

Immunotherapy is the new era in cancer treatment: Doctors explain

Hindustan Times  

There are several ways to treat cancer – from surgery to chemotherapy. Addressing this, Dr. Sewanti Limaye, Director, Oncology and Precision medicine, Sir HN Reliance Foundation Hospital spoke to HT Lifestyle, and said, “Decoding of the human genome in the early 2000s brought about revolutionary changes in cancer treatment with the discovery of cancer-related genetic pathways that could be targeted …

Targeted therapy shows benefit for people with advanced breast cancer in late-stage trial
2 years, 3 months ago

Targeted therapy shows benefit for people with advanced breast cancer in late-stage trial

CNN  

CNN — An experimental treatment shows promise for people with the most common form of advanced-stage breast cancer, according to results from a Phase 3 clinical trial. It showed that AstraZeneca’s capivasertib – in combination with Faslodex, an endocrine therapy already used to treat advanced breast cancer – gave people a median of 7.2 months without disease progression, compared with …

Indian origin patient among those healed completely of cancer in drug trial
2 years, 9 months ago

Indian origin patient among those healed completely of cancer in drug trial

India TV News  

An Indian origin patient was among those who had a "miracle" cure using a cancer medication that is being tried out by a research centre here achieving an unprecedented healing rate when all 14 patients in the trial had their cancers disappear. In the trial at the Memorial Sloan Kettering Cancer Center in New York using dostarlimab, "the rectal cancer …

"Breakthrough's" James Allison is having fun and curing cancer
5 years, 6 months ago

"Breakthrough's" James Allison is having fun and curing cancer

Salon  

Dr. James Allison doesn't look the part. He's also a Nobel laureate, a man whose unwavering faith in and curiosity about the human immune system led to one of the most revolutionary developments in cancer research in over a century. When you'd get up to the point of saying, "Well, we're going to do immunotherapy," that's when skepticism started coming …

Last resort cancer immunotherapy treatments should become first choice, experts say after trial success
6 years, 5 months ago

Last resort cancer immunotherapy treatments should become first choice, experts say after trial success

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy Cutting edge cancer treatments which are currently held back as a …

​Hyderabad: Immunotherapy out of reach for patients
6 years, 7 months ago

​Hyderabad: Immunotherapy out of reach for patients

Deccan Chronicle  

Hyderabad: There are three molecules of immunotherapy drugs that are available for cancer treatment in India. Immunotherapy or targeted therapy is a personalized treatment where the immune cells in the body are enhanced to fight and destroy the cancer cells. Senior Surgical Oncologist at Omega Hospitals Dr Mohana Vamsy explained, “Immunotherapy has shown good results in treating cancer patients. The …

‘I have definitely hit the jackpot.’ Advanced breast cancer disappears after new immunotherapy
6 years, 9 months ago

‘I have definitely hit the jackpot.’ Advanced breast cancer disappears after new immunotherapy

LA Times  

In the all-hands effort to harness the powers of the immune system to fight cancer, scientists have reported a new approach that eliminated all evidence of advanced-stage breast cancer in a 49-year-old woman who had run out of treatment options. “Now,” Perkins said, “I’m the golden guinea pig.” Indeed, Perkins’ response to the immunotherapy treatment is “unprecedented,” Laszlo G. Radvanyi …

Human trials start with cancer treatment that primes immune system to kill off tumours
7 years, 1 month ago

Human trials start with cancer treatment that primes immune system to kill off tumours

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Please enter a valid email address Please enter a valid email address SIGN UP I would like to be emailed about offers, events and updates from The Independent. Please try again later {{ /verifyErrors }} Human trials …

Killing cancer from the inside out
8 years, 11 months ago

Killing cancer from the inside out

Live Mint  

New York: The cure for cancer has been called the last frontier of medicine. US President Barack Obama recently called for a ‘moonshot’ to find safe and effective ways of eliminating cancer cells from our bodies. But for Dr. Steven Rosenberg of the National Cancer Institute in Bethesda, Maryland, the cure is very near—inside our own bodies, in fact. Instead …

My "truly remarkable" cancer breakthrough
11 years, 10 months ago

My "truly remarkable" cancer breakthrough

Salon  

I've spent my whole career trying to make some kind of a name for myself. But the first abstract from the report my doctor, Jedd Wolchok, will be presenting at the ASCO annual meeting starting May 31 was released Wednesday – and even in a cancer news week dominated by Angelina Jolie and prophylactic mastectomies, the findings still managed to …

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