Dexamethasone shows promise in treatment of severely ill COVID-19 patients: All you need to know about the steroid drug
4 years, 6 months ago

Dexamethasone shows promise in treatment of severely ill COVID-19 patients: All you need to know about the steroid drug

Firstpost  

The Oxford University announced that dexamethasone, a common steroid drug, has shown promise in the treatment of severely ill COVID-19 patients by improving their survival rate by at least 20 percent The Oxford University announced that dexamethasone, a common steroid drug, has shown promise in the treatment of severely ill COVID-19 patients by improving their survival rate by at least 20 percent. Shortly after the announcement, the government of the UK reportedly announced that the drug would be authorised for the treatment of COVID-19 patients who are on ventilators or receiving oxygen therapy. Congratulating the UK government, researchers and all others involved, WHO’s director-general Dr Tedros Adhanom Ghebreyesus said in a press release on Tuesday that this is great news as it is “the first treatment to be shown to reduce mortality in patients with COVID-19 requiring oxygen or ventilator support”. According to the WHO, dexamethasone is a corticosteroid drug that has been used since the 1960s to treat inflammatory conditions like asthma, atopic dermatitis and conditions of the gut, liver, kidneys and endocrine system and certain cancers.

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History of this topic

High-dose Covid treatment less effective in India than Europe: Lancet study
1 year, 1 month ago

High-dose Covid treatment less effective in India than Europe: Lancet study

Hindustan Times  

A higher dose of the steroid drug, dexamethasone, may have less beneficial effects for COVID-19 patients in India as compared with those in Europe, according to a study published in The Lancet Regional Health - Southeast Asia journal. The study looked at how well a strong dose of dexamethasone worked for COVID-19 patients. The team, including researchers from Copenhagen University …

Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study
2 years, 10 months ago

Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study

Hindustan Times  

An anti-inflammatory drug normally used to treat rheumatoid arthritis reduces the risk of death when given to hospitalised patients with severe Covid-19, according to a study led by researchers at the University of Oxford. Arthritis drug reduces death risk in patients hospitalised with Covid-19: Study The benefit of baricitinib is in addition to those of dexamethasone and tocilizumab, two other …

Health experts clash over use of certain drugs for COVID-19
4 years, 1 month ago

Health experts clash over use of certain drugs for COVID-19

Associated Press  

Health officials around the world are clashing over the use of certain drugs for COVID-19, leading to different treatment options for patients depending on where they live. On Friday, a World Health Organization guidelines panel advised against using the antiviral remdesivir for hospitalized patients, saying there’s no evidence it improves survival or avoids the need for breathing machines. Within the …

WHO advises against use of remdesivir for treating COVID-19
4 years, 1 month ago

WHO advises against use of remdesivir for treating COVID-19

Al Jazeera  

Global health agency says there is no evidence that drug improves survival rates or reduces need for ventilation. A World Health Organization expert panel has advised against the use of the antiviral drug remdesivir for patients admitted to hospital with COVID-19, regardless of how severely ill they are, because there is currently no evidence that it improves survival or the …

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists
4 years, 1 month ago

Steroid Treatment Should Be Reserved for Sickest Covid-19 Patients, Say Scientists

News 18  

Most adults with moderate-to-severe COVID-19 have a suppressed immune response against the novel coronavirus rather than life-threatening hyper-inflammation, according to a study which suggests steroids such as dexamethasone should be reserved for the sickest patients. According to the research, published in the journal Science Advances, fewer than 5 per cent of the COVID-19 patients, including some of the sickest individuals, …

'Proning' Covid Patients Seems to Save Lives. But How Many?
4 years, 1 month ago

'Proning' Covid Patients Seems to Save Lives. But How Many?

Wired  

The pandemic continues to rage in the US, and the number of people hospitalized with Covid-19 has now surpassed its prior peaks of about 60,000 in April and July. In 1976, a community ICU nurse in central Michigan named Margaret Piehl and Robert Brown, a doctor who had served in Vietnam, co-authored a paper detailing their observations that prone positioning …

Steroids to Covid-19 Patients Who Don't Require Oxygen May Increase Severity: PGIMER
4 years, 3 months ago

Steroids to Covid-19 Patients Who Don't Require Oxygen May Increase Severity: PGIMER

News 18  

The Post Graduate Institute of Medical Education and Research, Chandigarh has noted that the seriousness of the COVID patients coming to hospitals has surged recently. One of the reasons observed behind the surge is the indiscriminate use of steroids in the cases of COVID-19 at an initial stage, the institute stated on Thursday. “It has been observed by experts here …

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients
4 years, 3 months ago

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients

NPR  

Trump Was Treated With Steroids: How These Drugs Are Used For COVID-19 Patients Enlarge this image toggle caption Nati Harnik/AP Nati Harnik/AP Editor's note: Since we published this story, Trump's physician said that the president has completed his treatment for COVID-19. The steroid, dexamethasone, is now part of the "standard of care" for COVID-19, said Dr. Celine Gounder, assistant professor …

Dexamethasone: What is the new life-saving coronavirus drug?
4 years, 3 months ago

Dexamethasone: What is the new life-saving coronavirus drug?

The Independent  

Sign up to our free Living Well email for advice on living a happier, healthier and longer life Live your life healthier and happier with our free weekly Living Well newsletter Live your life healthier and happier with our free weekly Living Well newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. …

Steroids can be lifesaving for a few seriously ill COVID-19 patients, new studies suggests
4 years, 4 months ago

Steroids can be lifesaving for a few seriously ill COVID-19 patients, new studies suggests

Firstpost  

WHO warned against indiscriminate use of steroids, emphasizing that patients who are not severely ill are unlikely to benefit and may suffer side effects. International clinical trials published Wednesday confirm the hope that cheap, widely available steroid drugs can help seriously ill patients survive COVID-19, the illness caused by the coronavirus. Based on the new evidence, the World Health Organization …

Covid-19 drug treatment evaluated by EMA & Dutch regulator
4 years, 4 months ago

Covid-19 drug treatment evaluated by EMA & Dutch regulator

NL Times  

A name brand version of a cheap and widely available anti-inflammatory steroid will be assessed by the European Medicines Agency to determine if it can be recommended as a treatment option for adult patients suffering from Covid-19. Its use was also being researched by the Dutch Medicines Evaluation Board, according to AD, which previously evaluated remdesivir, an anti-viral intravenous drug …

Common steroids reduce deaths among critically ill Covid-19 patients, new analysis confirms
4 years, 4 months ago

Common steroids reduce deaths among critically ill Covid-19 patients, new analysis confirms

CNN  

CNN — New research released on Wednesday confirms that common, affordable steroids can reduce deaths among critically ill Covid-19 patients. “The treatment with corticosteroids reduces mortality of 40% to 32%, that’s a 20% relative reduction, or if you like to a better way to think about it, an easier way to think about, it is that out of every hundred …

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients
4 years, 4 months ago

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients

NPR  

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients Enlarge this image toggle caption Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images Three new studies strongly support using inexpensive and widely available drugs to treat people who are seriously ill with COVID-19. Sponsor Message "Giving steroids to COVID-19 could have been …

A blood test can tell which COVID-19 patient should get steroid treatment and who would react adversely to it
4 years, 5 months ago

A blood test can tell which COVID-19 patient should get steroid treatment and who would react adversely to it

Firstpost  

The study suggested steroid therapy may benefit patients with severe inflammation, but may negatively impact those with less severe inflammation COVID-19 has affected more than 15 million people in the world so far. Now, a group of researchers at the Albert Einstein College of Medicine say that the levels of CRP may have something to do with the effects of …

Seriously ill Covid patients showing major improvement after experimental treatment
4 years, 5 months ago

Seriously ill Covid patients showing major improvement after experimental treatment

NL Times  

Seriously ill Covid-19 patients can greatly benefit from treatment with corticosteroids, possibly in combination with a medicine that slows the functioning of the immune system, according to researchers from the Zuyderland Medical Center in Geleen and Heerlen. In their hospital, this experimental treatment reduced mortality in this patient group by as much as 65 percent, NOS reports. The doctors at …

COVID-19 RECOVERY trial: HIV medicine found ineffective in treating hospitalised COVID-19 patients
4 years, 6 months ago

COVID-19 RECOVERY trial: HIV medicine found ineffective in treating hospitalised COVID-19 patients

Firstpost  

The HIV combination treatment lopinavir-ritonavir is also being studied in a trial by the World Health Organization. A combination of antiviral drugs used to treat HIV had no beneficial effect in patients hospitalised with COVID-19 in a large-scale randomised trial, British scientists said on Monday. Scientists running the RECOVERY trial at the University of Oxford said that the results “convincingly …

Centre includes includes dexamethasone drug in COVID-19 treatment protocol for moderate to severe cases
4 years, 6 months ago

Centre includes includes dexamethasone drug in COVID-19 treatment protocol for moderate to severe cases

Firstpost  

The updated protocol includes the advice to use dexamethasone as an alternative choice to methylprednisolone for managing moderate to severe cases of COVID-19. New Delhi: An inexpensive, widely used steroid dexamethasone was included in the treatment protocols for COVID-19 patients in moderate to severe stages of illness among other therapeutic measures by the Union health ministry on Saturday. According to …

Dutch pharma sees dexametasone demand rising after Covid-19 treatment study
4 years, 6 months ago

Dutch pharma sees dexametasone demand rising after Covid-19 treatment study

NL Times  

A spike in demand for anti-inflammatory steroid dexamethasone could send prices of the drug higher after researchers at Oxford University showed it could provide relief to some Covid-19 patients. A drug price comparison tool provided by the Dutch government shows that dexamethasone costs about 11 cents per day for tablets, while in liquid form for use intravenously, prices start at …

Doctor’s Note: Can dexamethasone treat COVID-19?
4 years, 6 months ago

Doctor’s Note: Can dexamethasone treat COVID-19?

Al Jazeera  

With the coronavirus pandemic tightening its grip on the world and economies grinding to a standstill, the race is on to find a vaccine. In March, the World Health Organization announced a large global trial, called Solidarity, to find out whether any existing drugs can treat infections caused by COVID-19. What we do know about patients that suffer the worst …

A step towards recovery
4 years, 6 months ago

A step towards recovery

The Hindu  

At a time when COVID-19 has claimed over 4,40,000 lives worldwide and a vaccine or cure is still a long way off, a breakthrough finding in the United Kingdom randomised trial presents a slender ray of hope. From among the trials of six drugs for treating COVID-19, one trial that used low-dose dexamethasone, a commonly available steroid used to reduce …

Dexamethasone: US doctors cast doubt on UK’s coronavirus ‘breakthrough’
4 years, 6 months ago

Dexamethasone: US doctors cast doubt on UK’s coronavirus ‘breakthrough’

The Independent  

Sign up to our free weekly IndyTech newsletter delivered straight to your inbox Sign up to our free IndyTech newsletter Sign up to our free IndyTech newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. Professor Peter Horby of Oxford University said the Recovery Trial project findings show the drug would, on …

Dexamethasone | WHO says more understanding needed on steroid
4 years, 6 months ago

Dexamethasone | WHO says more understanding needed on steroid

The Hindu  

The emergencies chief of the World Health Organization welcomed the news this week that dexamethasone, a cheap steroid, was shown in a British trial to reduce deaths among patients critically ill with the coronavirus, but said it was too soon to change how patients are treated. “It’s one of the breakthroughs we’re going to need to effectively deal with COVID-19, …

WHO moves to update Covid-19 guidance after ’major breakthrough’ in drug study
4 years, 6 months ago

WHO moves to update Covid-19 guidance after ’major breakthrough’ in drug study

Live Mint  

The World Health Organization said it was moving to update its guidelines on treating people stricken with Covid-19 to reflect results of a clinical trial that showed a cheap, common steroid can help save critically ill patients. Trial results announced on Tuesday by researchers in Britain showed dexamethasone, used since the 1960s to reduce inflammation in diseases such as arthritis, …

Steroid dexamethasone approved for use in COVID-19 treatment in U.K.
4 years, 6 months ago

Steroid dexamethasone approved for use in COVID-19 treatment in U.K.

The Hindu  

The U.K. government on Wednesday authorised the State-funded National Health Service to use steroid, the world’s first coronavirus treatment proven to reduce the risk of death among severely ill patients. The Department of Health said the cheap and widely available anti-inflammatory steroid has been immediately approved to treat all hospitalised COVID-19 patients requiring oxygen, including those on ventilators, after an …

COVID-19 'RECOVERY' Trial: Dexamethasone found life-saving in seriously-ill patients in preliminary tests
4 years, 6 months ago

COVID-19 'RECOVERY' Trial: Dexamethasone found life-saving in seriously-ill patients in preliminary tests

Firstpost  

As part of the Recovery trial, a range of potential treatments is being tested in consenting COVID-19 patients admitted to NHS hospitals in the UK. “This is the most important trial result for COVID-19 so far,” Chris Whitty, England’s Chief Medical Officer, said on Twitter about the findings of the UK-led clinical trial known as ‘RECOVERY’. “This is the first …

Dexamethasone: A magical Corona drug that you should take only on prescription
4 years, 6 months ago

Dexamethasone: A magical Corona drug that you should take only on prescription

India Today  

Before a Covid-19 specific drug formula is found, a magical cure has been found to treat novel coronavirus infection. The researchers administered dexamethasone to around 2,100 patients in hospitals and compared their recovery with another set of over 4,300 patients who were not given the drug. They found dexamethasone to be a life-saving drug for Covid-19 patients. The researchers at …

‘Breakthrough’: WHO hails steroid treatment for coronavirus
4 years, 6 months ago

‘Breakthrough’: WHO hails steroid treatment for coronavirus

Al Jazeera  

UK study shows dexamethasone reduces deaths by about 30 percent in critical COVID patients, some US doctors sceptical. The World Health Organization plans to update its guidelines on treating people stricken with coronavirus to reflect results of a clinical trial that showed a cheap, common steroid could help save critically ill patients. ‘Best piece of news’ Britain’s health minister on …

How dexamethasone might lead researchers to better COVID-19 treatments
4 years, 6 months ago

How dexamethasone might lead researchers to better COVID-19 treatments

LA Times  

The steroid drug dexamethasone can be lifesaving for patients with severe COVID-19. In preliminary clinical trial results announced Tuesday, patients on mechanical ventilators who were treated with the steroid dexamethasone were 35% less likely to die of COVID-19 than their counterparts who got standard care without the drug. A medication like dexamethasone is a “blunt instrument,” said Dr. Steven J. …

Dexamethasone could be the miracle drug to reduce COVID-19 mortality rate
4 years, 6 months ago

Dexamethasone could be the miracle drug to reduce COVID-19 mortality rate

Deccan Chronicle  

New Delhi: For countries battling high mortality rate due to the coronavirus pandemic, steroid Dexamethasone can be a boon, as researchers in England have claimed that it can reduce COVID-19 deaths by one-third in severely ill hospitalised patients. The chief investigators of the randomised evaluation of COVID -19 therapy trial said low-cost Dexamethasone reduces death by up to one-third in …

Dexamethasone: UK approves NHS use of life-saving drug for severely ill coronavirus patients
4 years, 6 months ago

Dexamethasone: UK approves NHS use of life-saving drug for severely ill coronavirus patients

The Independent  

Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our privacy policy The government has authorised the use of a drug which has …

Indian doctors express cautious endorsement for dexamethasone for COVID-19
4 years, 6 months ago

Indian doctors express cautious endorsement for dexamethasone for COVID-19

The Hindu  

Indian doctors have said the reported success of dexamethasone — an inexpensive steroid that retails for less than ₹10 for 10 ml and is made by several Indian manufacturers — at curing COVID-19 patients on ventilators is good news for India. Scientists administering the WHO-administered RECOVERY trial — the largest global clinical trial — that is checking the ability of …

Major COVID-19 breakthrough: A cheap Dexamethasone drug 'reduces risk of death in ventilated patients'
4 years, 6 months ago

Major COVID-19 breakthrough: A cheap Dexamethasone drug 'reduces risk of death in ventilated patients'

India TV News  

A cheap, widely available steroid called dexamethasone reduced deaths by up to one third in severely ill hospitalized patients. “Dexamethasone must now be rolled out and accessed by thousands of critically ill patients around the world,” said Cammack, who had no role in the study. Researchers estimated that the drug would prevent one death for every eight patients treated while …

Coronavirus | Dexamethasone reduces deaths from COVID-19, say researchers in U.K.
4 years, 6 months ago

Coronavirus | Dexamethasone reduces deaths from COVID-19, say researchers in U.K.

The Hindu  

Researchers in the U.K. say they have the first evidence that a drug can improve COVID-19 survival: A steroid called dexamethasone reduced deaths by up to one third in severely ill hospitalised patients. The study is a large, strict test that randomly assigned 2,104 patients to get the drug and compared them with 4,321 patients getting only usual care. “The …

Coronavirus: £5 steroid dexamethasone 'reduces risk of death'
4 years, 6 months ago

Coronavirus: £5 steroid dexamethasone 'reduces risk of death'

Daily Mail  

Prime Minister Boris Johnson today hailed the 'biggest breakthrough yet' in the UK's coronavirus fight as officials announced they have found a drug that could save up to a third of critically-ill Covid-19 patients. In other coronavirus developments in Britain today: Two women travelling to New Zealand to visit a dying parent tested positive for Covid-19, ending the country's 24-day …

Steroid drug: A ‘breakthrough’ in the fight against coronavirus?
4 years, 6 months ago

Steroid drug: A ‘breakthrough’ in the fight against coronavirus?

Al Jazeera  

UK has approved the drug use in the state-run health service and stockpiled 200,000 courses of the treatment. A cheap and widely-used steroid called dexamethasone has become the first drug shown to be able to save lives among COVID-19 patients in what scientists said is a “major breakthrough” in the coronavirus pandemic. “This is a result that shows that if …

Dexamethasone reduces death risk in severe COVID-19 cases: Trial
4 years, 6 months ago

Dexamethasone reduces death risk in severe COVID-19 cases: Trial

Al Jazeera  

Steroid cuts risk of death by a third for patients on ventilators, by a fifth for those on oxygen, researchers say. “Based on these results, one death would be prevented by treatment of around 8 ventilated patients or around 25 patients requiring oxygen alone,” a University of Oxford statement said. Dexamethasone is inexpensive, on the shelf, and can be used …

Dexamethasone can improve COVID-19 survival, study shows
4 years, 6 months ago

Dexamethasone can improve COVID-19 survival, study shows

LA Times  

In a development that could dramatically shrink the death toll of the COVID-19 pandemic, British researchers have found that a cheap and readily available steroid prevented more than a third of the sickest patients from dying. If people are tempted to use it inappropriately, it “will cause much sicker patients,” said Dr. Steven J. O’Day, director of regional research at …

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients
4 years, 6 months ago

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients

NPR  

Early Results Show Benefit Of Steroid For Very Sick COVID-19 Patients toggle caption John Minchillo/AP A low-cost anti-inflammatory drug appears to reduce the risk of death in patients with COVID-19. Sponsor Message "Dexamethasone reduced deaths by one-third in ventilated patients," according to a news release from the RECOVERY trial organizers, "and by one fifth in other patients receiving oxygen only." …

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