Op-Ed: Immunity’s down. Infection rates are up. And what happened to everyone’s masks?
LA TimesIn March 2021, a restaurant in Houston informed patrons they must mask up. This is part of a global COVID wave, being seen throughout much of Europe, South America and the Middle East and in China, Japan, South Korea, Australia and New Zealand. By four to six months after vaccination or a booster shot, there is a substantial drop-off of neutralizing antibodies and protection against hospitalization — though that protection is largely restored by a new booster shot. Notably, BQ.1.1 and another variant, XBB, are the two strains most effective at escaping our immune response, so effective that they resist all commercially available monoclonal antibodies and Evusheld, a combination antibody used to prevent the toll of infections in the immunocompromised. We’ve lost the powerful monoclonal antibodies as effective treatment backstops or for helping bolster protection for more than 7 million Americans who are immunocompromised.